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585 listings
  • Price Drop
    $41,250
    great price
    $4,771 below market
    • 45,050 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • NOLA Motorcars (49 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Metairie, LA / 49 miles away from Picayune, MS

    Color Heads Up Display, Cold Weather Package, Power Folding Heated Rear Seats, Heated/Ventilated Front Seats, LUXURY Package, Navigation System w/ Mar...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2JZMAA6NC229168
    Stock: 229168
    Certified Pre-Owned: No
    Listed since: 07-07-2025

  • Price Drop
    $38,650
    fair price
    $21 below market
    • 48,900 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • NOLA Motorcars (49 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Metairie, LA / 49 miles away from Picayune, MS

    The 2022 Lexus RX includes a suite of advanced safety features, such as adaptive cruise control, lane departure warning, and automatic emergency braki...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA2NC230655
    Stock: 230655a
    Certified Pre-Owned: No
    Listed since: 06-12-2025

  • Price Drop
    $20,900
    fair price
    $757 below market
    • 121,261 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • Ralph Sellers Hyundai (79 mi away)
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Gonzales, LA / 79 miles away from Picayune, MS

    Heated Seats, Moonroof, Aluminum Wheels, CD Player, Bluetooth®, iPod/MP3 Input, Satellite Radio, Back-Up Camera, HEATED ESPRESSO WALNUT STEERING WHEEL...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA5HC057185
    Stock: 25H0652A
    Certified Pre-Owned: No
    Listed since: 07-23-2025

  • New Listing
    $15,217
    fair price
    $40 below market
    • 142,621 miles
    • 5 Seats, 18 City / 25 Hwy MPG
    • Honda of Slidell (22 mi away)
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • USB Inputs
    • Power Liftgate/Trunk
    Close

    Located in Slidell, LA / 22 miles away from Picayune, MS

    Heated Seats, Sunroof, Navigation, Dual Zone A/C, Keyless Start, Multi-CD Changer, iPod/MP3 Input, Power Liftgate, WOOD & LEATHER-TRIMMED STEERING WHE...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    21 Combined MPG (18 City/25 Highway)

    Listing Information:

    VIN: 2T2ZK1BA3EC137567
    Stock: EC137567
    Certified Pre-Owned: No
    Listed since: 08-14-2025

  • $22,882
    good price
    $1,339 below market
    • 70,973 miles
    • 1 accident, 4 owners, corporate fleet vehicle
    • 5 Seats, 20 City / 28 Hwy MPG
    • AutoNation Ford Mobile (92 mi away)
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Mobile, AL / 92 miles away from Picayune, MS

    12.3" Navigation SystemWheels: 20" X 8" Split 5-Spoke Dark SilverPower Tilt & Slide MoonroofPremium PackageHeated & Ventilated Front SeatsLexus S...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: 2T2ZZMCA1GC031701
    Stock: GC031701
    Certified Pre-Owned: No
    Listed since: 06-10-2025

  • Price Drop
    $40,500
    fair price
    $1,147 above market
    • 39,600 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • NOLA Motorcars (49 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Metairie, LA / 49 miles away from Picayune, MS

    The 2022 Lexus RX includes a suite of advanced safety features, such as adaptive cruise control, lane departure warning, and automatic emergency braki...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA0NC229035
    Stock: 229035
    Certified Pre-Owned: No
    Listed since: 07-21-2025

  • $28,998
    fair price
    $632 above market
    • 58,419 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • CarMax North Shore (26 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Covington, LA / 26 miles away from Picayune, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA6HC064910
    Stock: 27568456
    Certified Pre-Owned: No

    • 9,235 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • CarMax Kenner (52 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Kenner, LA / 52 miles away from Picayune, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA8MC202535
    Stock: 27204905
    Certified Pre-Owned: No

  • New Listing
    • 107,785 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • CarMax Baton Rouge (84 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Power Driver Seat
    Close

    Located in Baton Rouge, LA / 84 miles away from Picayune, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA4JC094539
    Stock: 27541052
    Certified Pre-Owned: No

  • New Listing
    • 57,220 miles
    • No accidents, 3 owners, personal use
    • 5 Seats, 20 City / 28 Hwy MPG
    • Lakeside Toyota (49 mi away)
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Metairie, LA / 49 miles away from Picayune, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: 2T2ZZMCA6GC027630
    Stock: 13873K1
    Certified Pre-Owned: No
    Listed since: 08-06-2025

  • New Listing
    • 50,109 miles
    • No accidents, 3 owners, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • CarMax Mobile (92 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Mobile, AL / 92 miles away from Picayune, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2ZZMCA9HC043354
    Stock: 27113118
    Certified Pre-Owned: No

    • 46,000 miles
    • 1 accident, 2 owners, personal use only
    • 5 Seats, 18 City / 25 Hwy MPG
    • CarMax North Shore (26 mi away)
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • USB Inputs
    • Power Liftgate/Trunk
    Close

    Located in Covington, LA / 26 miles away from Picayune, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    21 Combined MPG (18 City/25 Highway)

    Listing Information:

    VIN: 2T2ZK1BA4DC095327
    Stock: 26951659
    Certified Pre-Owned: No

    • 104,274 miles
    • 2 accidents, 4 owners, personal use
    • 5 Seats, 18 City / 25 Hwy MPG
    • CarMax Baton Rouge (84 mi away)
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • USB Inputs
    • Power Liftgate/Trunk
    Close

    Located in Baton Rouge, LA / 84 miles away from Picayune, MS

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    21 Combined MPG (18 City/25 Highway)

    Listing Information:

    VIN: 2T2ZK1BA0EC136764
    Stock: 27540922
    Certified Pre-Owned: No

  • New Listing
    $34,871
    fair price
    $1,081 below market
    • 55,001 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Royal Nissan (84 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Baton Rouge, LA / 84 miles away from Picayune, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAAXMC185639
    Stock: XS41350A
    Certified Pre-Owned: No

  • New Listing
    • 73,563 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 18 City / 25 Hwy MPG
    • Carvana - New Orleans (48 mi away)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Power Driver Seat
    • Tire Pressure Warnin...
    Close

    Located in New Orleans, LA / 48 miles away from Picayune, MS

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    21 Combined MPG (18 City/25 Highway)

    Listing Information:

    VIN: 2T2ZK1BA8FC191853
    Stock: 2003898572
    Certified Pre-Owned: No
    Listed since: 07-26-2025

  • Price Drop
    • 119,568 miles
    • 1 accident, 2 owners, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Supreme Chevrolet (78 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Gonzales, LA / 78 miles away from Picayune, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA3HC065562
    Stock: SC18638B
    Certified Pre-Owned: No
    Listed since: 06-06-2025

  • $13,995
    good price
    $910 below market
    • 118,725 miles
    • 2 accidents, 4 owners, personal use only
    • 5 Seats, 18 City / 25 Hwy MPG
    • Dean Mitchell Auto Mall (92 mi away)
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • USB Inputs
    • Power Liftgate/Trunk
    Close

    Located in Mobile, AL / 92 miles away from Picayune, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    21 Combined MPG (18 City/25 Highway)

    Listing Information:

    VIN: 2T2ZK1BA4DC106679
    Stock: AL106679
    Certified Pre-Owned: No

  • $11,995
    fair price
    $151 below market
    • 144,053 miles
    • 1 accident, 3 owners, personal use only
    • 5 Seats, 18 City / 25 Hwy MPG
    • Dean Mitchell Auto Mall (92 mi away)
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • USB Inputs
    • Multi-Zone Climate C...
    Close

    Located in Mobile, AL / 92 miles away from Picayune, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    21 Combined MPG (18 City/25 Highway)

    Listing Information:

    VIN: 2T2ZK1BA1CC078645
    Stock: AL078645
    Certified Pre-Owned: No

  • $20,995
    fair price
    $952 above market
    • 161,212 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Dean Mitchell Auto Mall (92 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Mobile, AL / 92 miles away from Picayune, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2BZMCA0GC053044
    Stock: AL053044
    Certified Pre-Owned: No

    • 189,313 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 18 City / 24 Hwy MPG
    • Dean Mitchell Auto Mall (92 mi away)
    • AWD/4WD
    • Bluetooth
    • Power Driver Seat
    • Tire Pressure Warnin...
    • USB Inputs
    Close

    Located in Mobile, AL / 92 miles away from Picayune, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    20 Combined MPG (18 City/24 Highway)

    Listing Information:

    VIN: 2T2BK1BA2DC200352
    Stock: AL200352
    Certified Pre-Owned: No

    • 130,850 miles
    • 2 accidents, 2 owners, personal use
    • 5 Seats, 18 City / 25 Hwy MPG
    • Ethan Hunt Automotive (86 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Power Driver Seat
    • Tire Pressure Warnin...
    Close

    Located in Mobile, AL / 86 miles away from Picayune, MS

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    21 Combined MPG (18 City/25 Highway)

    Listing Information:

    VIN: 2T2ZK1BA7FC186143
    Stock: M186143
    Certified Pre-Owned: No

Showing 1 - 21 out of 585 listings

Consumer Reviews for the Lexus RX 350

Read recent reviews for the Lexus RX 350
Overall Consumer Rating
4.2 out of 5 stars1,209 Reviews
Write a vehicle reviewSee all 1209 reviews
  • 5 star
    (60%)
  • 4 star
    (17%)
  • 3 star
    (10%)
  • 2 star
    (7%)
  • 1 star
    (6%)
4.75 out of 5 stars

Way better than new EPA mpg

Bob in Texas, 07/14/2008
2007 Lexus RX 350
I characterize the RX-350 as a luxury small SUV (most call it a medium size. With 270 hp it keeps the lead footers mostly pleased and for the more average to docile drivers the 26.8 mpg that I recorded on a 330 mile stint on interstate 10 on cruise control at 71 mph is EPA busting. On a 1040 mile trip I recorded an average of 25.8 mpg. Now mind you I never exceeded 75 mph on this trip, … but for the economy fan, where else are you going with that kind of power.
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More about the Lexus RX 350

Edmunds has 585 Used Lexus RX 350s for sale near you, including a 2012 RX 350 SUV and a 2021 RX 350 SUV ranging in price from $11,995 to $43,998.

How much is the used Lexus RX 350?

There are 585 used Lexus RX 350 vehicles for sale near you, with an average cost of $25,559.
Edmunds found one or more Great deals on a used Lexus RX 350 near you, starting at $41,250.

Is the used Lexus RX 350 a good car?

The used Lexus RX 350 received an average score of 4.2 out of 5 based on 1,209 consumer reviews at Edmunds. If you want to learn more about the Lexus RX 350, read Edmunds' expert review.
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