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1,523 listings
  • $39,990
    great price
    $4,452 below market
    • 17,482 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Phoenix, AZ / 1,148 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2AZMAA0NC238674
    Stock: 2003988793
    Certified Pre-Owned: No
    Listed since: 09-16-2025

  • New Listing
    Stock photo**
    • 15,652 miles
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Milwaukee (310 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Milwaukee, WI / 310 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCAXPC031852
    Stock: PWS8127
    Certified Pre-Owned: No
    Listed since: 09-23-2025

  • Price Drop
    $37,186
    great price
    $4,876 below market
    • 51,003 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Jones Chevrolet Humboldt (479 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Humboldt, TN / 479 miles away from Des Moines, IA

    Free Warranty for Life, Bluetooth, SiriusXM Radio, Wireless Charging, Power Driver Seat, Power Passenger Seat, Heated/Cooled Leather Seats, Sunroof/Mo...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA7NC258144
    Stock: H5952
    Certified Pre-Owned: No
    Listed since: 08-02-2025

  • $33,998
    great price
    $5,930 below market
    • 70,531 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CA to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Visalia, CA / 1,426 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA1NC356629
    Stock: 27788641
    Certified Pre-Owned: No

  • New Listing
    • 11,839 miles
    • 5 Seats, 20 City / 27 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Dallas, TX / 631 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA5NC232061
    Stock: 2004100014
    Certified Pre-Owned: No
    Listed since: 09-22-2025

  • $40,000
    great price
    $4,942 below market
    • 49,209 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • York Chrysler Dodge Jeep Ram Fiat (368 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Crawfordsville, IN / 368 miles away from Des Moines, IA

    2022 Lexus RX 350 F Sport 3.5L V6 DOHC 24V 8-Speed Automatic!!!NO ACCIDENTS!!!, FRESH OIL CHANGE AND DETAIL, HANDS FREE BLUETOOTH, LEATHER, NON SMOKER...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2SZMDA5NC360379
    Stock: 25152A
    Certified Pre-Owned: No
    Listed since: 09-10-2025

  • New Listing
    $41,998
    great price
    $5,972 below market
    • 33,087 miles
    • 5 Seats, 20 City / 27 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from NV to IA*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Henderson, NV / 1,210 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2JZMAA1NC226369
    Stock: 27658706
    Certified Pre-Owned: No

  • Price Drop
    $36,455
    great price
    $3,616 below market
    • 64,718 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Kenny Kent Lexus of Evansville (410 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Evansville, IN / 410 miles away from Des Moines, IA

    RX 350 F Sport, 4D Sport Utility, AWD, 12.3' Navigation System, 20' x 8' Aluminum Wheels, Auto Recirculation Air Conditioner, Color Heads-Up Display, ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2SZMDAXNC327510
    Stock: 2530816A
    Certified Pre-Owned: Yes
    Listed since: 08-12-2025

  • Price Drop
    $37,998
    great price
    $4,649 below market
    • 19,249 miles
    • 1 accident, 1 owner, corporate fleet vehicle
    • 5 Seats, 19 City / 26 Hwy MPG
    • Signature Auto Enterprises (286 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Schaumburg, IL / 286 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA4NC314293
    Stock: P61268
    Certified Pre-Owned: No
    Listed since: 08-21-2025

  • New Listing
    Stock photo**
    • 96,849 miles
    • 5 Seats, 19 City / 26 Hwy MPG
    • Walser Auto Campus (329 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Wichita, KS / 329 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDAXMC264305
    Stock: 54L1368T
    Certified Pre-Owned: No
    Listed since: 09-22-2025

  • New Listing
    $41,998
    good price
    $4,609 below market
    • 39,498 miles
    • 5 Seats, 19 City / 26 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CO to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Parker, CO / 602 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA6NC361468
    Stock: 27490828
    Certified Pre-Owned: No

  • Price Drop
    $37,850
    great price
    $3,539 below market
    • 77,564 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Forest Lake Ford (256 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Forest Lake, MN / 256 miles away from Des Moines, IA

    Certified. 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V CaviarThis vehicle comes with a wide range of features including, AWD, Black w/NuL...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA6NC310570
    Stock: FP1587
    Certified Pre-Owned: No
    Listed since: 09-04-2025

  • $35,300
    great price
    $3,294 below market
    • 76,607 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Spirit Lexus (264 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in St. Louis, MO / 264 miles away from Des Moines, IA

    Nebula Gray Pearl 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V ** LOCAL TRADE **, ** ONE OWNER **, **ANDROID AUTO**, **APPLE CARPLAY**, ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA9NC356538
    Stock: P8N356538
    Certified Pre-Owned: No
    Listed since: 08-19-2025

    • 45,224 miles
    • Frame damage reported, 2 owners, corporate fleet vehicle
    • 5 Seats, 20 City / 27 Hwy MPG
    • Baha Auto (305 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Chicago, IL / 305 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: Yes

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA1MC215997
    Stock: N23059TRTR
    Certified Pre-Owned: No

  • $43,990
    fair price
    $1,773 below market
    • 7,058 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Charlotte, NC / 821 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA4NC248123
    Stock: 2003721850
    Certified Pre-Owned: No
    Listed since: 07-22-2025

  • Price Drop
    $32,990
    great price
    $3,087 below market
    • 89,173 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • Lexus of Memphis (494 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Memphis, TN / 494 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA2NC258147
    Stock: 85054B
    Certified Pre-Owned: No
    Listed since: 08-09-2025

  • $31,995
    fair price
    $225 above market
    • 97,854 miles
    • 1 accident, 2 owners, corporate fleet vehicle
    • 5 Seats, 19 City / 26 Hwy MPG
    • Baha Auto (301 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Palos Hills, IL / 301 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2SZMDA8MC273848
    Stock: S32080
    Certified Pre-Owned: No

  • New Listing
    • 13,328 miles
    • Frame damage reported, 1 owner, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • Baha Auto (301 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Burbank, IL / 301 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: Yes

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3PC007151
    Stock: B32330
    Certified Pre-Owned: No

    • 32,362 miles
    • No accidents, 1 owner, corporate fleet vehicle
    • 5 Seats, 21 City / 28 Hwy MPG
    • Baha Auto (305 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Chicago, IL / 305 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7PC028178
    Stock: N22984
    Certified Pre-Owned: No

  • Price Drop
    $34,452
    great price
    $3,064 below market
    • 98,745 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Lexus of Tulsa (398 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Tulsa, OK / 398 miles away from Des Moines, IA

    Recent Arrival! CARFAX One-Owner. Clean CARFAX.Caviar Fresh Oil Change, Two Sets of Keys, Recently Detailed, AWD, Black Artificial Leather, 12.3" Navi...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA5NC355175
    Stock: SC117545A
    Certified Pre-Owned: No
    Listed since: 09-04-2025

  • New Listing
    • 18,904 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in San Antonio, TX / 884 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA2NC364593
    Stock: 2004089010
    Certified Pre-Owned: No
    Listed since: 09-22-2025

Showing 148 - 168 out of 1,523 listings

Consumer Reviews for the Lexus RX 350

Read recent reviews for the Lexus RX 350
Overall Consumer Rating
4.2 out of 5 stars44 Reviews
Write a vehicle reviewSee all 44 reviews
  • 5 star
    (66%)
  • 4 star
    (11%)
  • 3 star
    (7%)
  • 2 star
    (5%)
  • 1 star
    (11%)
1 out of 5 stars

Exhaust drones/vibrates between 1400/1900 RPM

AlanB, 09/30/2022
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A)
I have a new 2022 but the exhaust noise and corresponding vibration in the pedals and steering wheel is very annoying. Test drove another new 2022 today that did not have these issues. After two visits, a total of 11 days in the shop, and replacement of several parts the issue remains and Lexus has now washed their hands and told me that’s just too bad. It’s operating as intended in … their words, but obviously not, or they would not have worked on it two times and replaced parts. Very disappointed in Lexus quality and there their response to customer issues. If they don’t deal with this in a better fashion, they can put me down as a never again customer, and I warn everyone looking at ANY RX 350 to carefully check for this issue. All you have to do is leave the car in park, and very slowly rev the engine between idle and about 2000 RPM . If you hear any abnormal, droning , rumbling or vibrations run from the car, because Lexus will not fix it!
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Used 2022 Lexus RX 350 in Des Moines, IA Values

Estimated values
2022 Lexus RX 350 4dr SUV (3.5L 6cyl 8A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$31,569$33,378$35,265
Clean$31,148$32,916$34,758
Average$30,447$32,145$33,913
Rough$29,536$31,144$32,814

The average list price of a used 2022 Lexus RX 350 in Des Moines, Iowa is $39,228. The average mileage on a used Lexus RX 350 2022 for sale in Des Moines, Iowa is 48,854. Based on the average mileage of 48,854 for used 2022 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Des Moines, Iowa to be $30,447.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.