Skip to FiltersReport abuse
1,523 listings
- $38,999fair price$853 below market
- 42,926 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Enterprise Car Sales (In-stock online)
- Home delivery*
Close
Located in Reseda, CA / 1,445 miles away from Des Moines, IA
Transfer of vehicle from another location to your neighborhood Enterprise Car Sales may require payment of a non-refundable transfer fee to begin the ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA6NC254182
Stock: 8DH3TM
Certified Pre-Owned: No
Listed since: 08-13-2025 - Price Drop$35,995fair price$249 below market
- 75,520 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
Close
Located in Knoxville, TN / 650 miles away from Des Moines, IA
CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Keyless Start,Lane Keeping Assist,Remote Start,Satellite Radio,W...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAA0NC221647
Stock: NC221647P
Certified Pre-Owned: No - $47,934fair price$1,753 above market
- 10,696 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Toyota of Naperville (281 mi away)
Close
Located in Naperville, IL / 281 miles away from Des Moines, IA
2022 LEXUS RX 350 ONLY 10,696 MILES AWD ELEVATE YOUR DRIVING EXPERIENCE WITH THIS LOW-MILEAGE 2022 LEXUS RX 350. FINISHED IN ATOMIC SILVER WITH A LUXU...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC355165
Stock: T41332A
Certified Pre-Owned: No
Listed since: 09-10-2025 - New Listing$35,898fair price$318 below market
- 82,057 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Classic Toyota (300 mi away)
Close
Located in Waukegan, IL / 300 miles away from Des Moines, IA
Atomic Silver 2022 Lexus RX 350 AWD 8-Speed Automatic 4-Wheel Disc Brakes, 9 Speakers, ABS brakes, Air Conditioning, Alloy wheels, AM/FM radio: Sirius...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC317064
Stock: U3807
Certified Pre-Owned: No
Listed since: 05-30-2025 - $33,500good price$1,864 below market
- 45,286 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
Close
Located in Valencia, CA / 1,440 miles away from Des Moines, IA
Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Keyless Start,Lane Keeping Assist,Remote Start,Satellite Radio,WiF...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAAXNC255210
Stock: NC255210P
Certified Pre-Owned: No - New Listing$42,998fair price$585 above market
- 11,149 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- CarMax (In-stock online)
- Transfer available from AZ to IA*
Close
Located in Tolleson, AZ / 1,162 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA6NC245479
Stock: 27452060
Certified Pre-Owned: No - New Listing$41,990fair price$334 above market
- 51,340 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Atlanta, GA / 736 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA4NC348217
Stock: 2004037343
Certified Pre-Owned: No
Listed since: 09-22-2025 - $32,988fair price$424 below market
- 64,853 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Perillo BMW (310 mi away)
Close
Located in Chicago, IL / 310 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4LC227099
Stock: B48058B
Certified Pre-Owned: No
Listed since: 09-10-2025 - Price Drop$40,742good price$3,462 below market
- 40,721 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
Close
Located in Ramsey, NJ / 1,010 miles away from Des Moines, IA
CarFax No Accidents Reported,CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA2NC365856
Stock: L18112T
Certified Pre-Owned: No - $34,488good price$1,689 below market
- 63,956 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
Close
Located in Los Angeles, CA / 1,436 miles away from Des Moines, IA
CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Lane Keeping As...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA5NC249054
Stock: TU12393R
Certified Pre-Owned: No - Price Drop$40,590fair price$660 above market
- 40,016 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Charlotte, NC / 821 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC317328
Stock: 2004059843
Certified Pre-Owned: No
Listed since: 09-16-2025 - $40,995fair price$563 below market
- 52,419 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Perkins Motor Plex Mayfield (427 mi away)
Close
Located in Mayfield, KY / 427 miles away from Des Moines, IA
**FULLY SERVICED AND INSPECTED** **30 DAY POWERTRAIN PLUS WARRANTY**.....ALL WHEEL DRIVE.....PREFERRED ACCESSORY PACKAGE.....20 INCH SPLIT FIVE SPOKE ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXNC326819
Stock: 326819
Certified Pre-Owned: No
Listed since: 08-21-2025 - $40,000good price$2,942 below market
- 60,869 miles
- 1 accident, 2 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Olathe Toyota (196 mi away)
Close
Located in Olathe, KS / 196 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA0NC343659
Stock: T34612A
Certified Pre-Owned: No
Listed since: 07-11-2025 - New Listing$30,990fair price$90 below market
- 74,528 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Carvana - Memphis (491 mi away)
- Home delivery*
Close
Located in Memphis, TN / 491 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA5LC153275
Stock: 2004070436
Certified Pre-Owned: No
Listed since: 09-13-2025 - $40,000fair price$102 above market
- 18,879 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
Close
Located in Ramsey, NJ / 1,010 miles away from Des Moines, IA
CarFax No Accidents Reported,CarFax 1-Owner,Low Mileage,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Keyless St...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2AZMDA2NC362134
Stock: T26155P
Certified Pre-Owned: No - Price Drop$41,975fair price$966 below market
- 26,812 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Arlington Heights Buick GMC (293 mi away)
Close
Located in Arlington Heights, IL / 293 miles away from Des Moines, IA
RX 350!! F-SPORT!! AWD!! CARFAX 1-OWNER!! LED FRONT FOG LAMPS!! HEATED & COOLED LEATHER SEATING!! POWER GLASS SUNROOF!! F-SPORT HEATED PERFORATED LEAT...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA3NC344021
Stock: BP3419
Certified Pre-Owned: No
Listed since: 05-22-2025 - New Listing$47,988fair price$46 below market
- 21,023 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Naperville (281 mi away)
Close
Located in Naperville, IL / 281 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA4NC335571
Stock: 260018A
Certified Pre-Owned: No
Listed since: 09-20-2025 - Price Drop$37,776fair price$285 below market
- 63,913 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Everett Buick GMC (486 mi away)
Close
Located in Bryant, AR / 486 miles away from Des Moines, IA
CARFAX One-Owner. 3.5L V6 DOHC 24V CALL 501-315-7100 AND DISCOVER THE DIFFERENCE! @ EverettBGMC.com, ONE OWNER, CLEAN CARFAX, BACKUP CAMERA, BLUETOOTH...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA5NC222002
Stock: NC222002
Certified Pre-Owned: No
Listed since: 09-01-2025 - Price Drop$40,041good price$2,193 below market
- 66,438 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Kenny Kent Lexus of Evansville (410 mi away)
Close
Located in Evansville, IN / 410 miles away from Des Moines, IA
Recent Arrival! CARFAX One-Owner. Clean CARFAX. Certified. L/Certified Details: * Warranty Deductible: $0 * Vehicle History * CERTIFIED WARRANTY: Unli...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3NC365588
Stock: 2530884A
Certified Pre-Owned: Yes
Listed since: 09-16-2025 - $42,939fair price$1,011 below market
- 19,610 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Smart Ford (499 mi away)
Close
Located in Malvern, AR / 499 miles away from Des Moines, IA
This vehicle won't be on the lot long! You'll be impressed by a spectacular blend of technology, style and refinement. With less than 20,000 miles on ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA4NC244847
Stock: NC244847
Certified Pre-Owned: No
Listed since: 06-25-2025 - $45,000fair price$619 below market
- 32,854 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Rockford (244 mi away)
Close
Located in Loves Park, IL / 244 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA4NC359045
Stock: B359045A
Certified Pre-Owned: No
Listed since: 03-18-2025
Showing 190 - 210 out of 1,523 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Exhaust drones/vibrates between 1400/1900 RPM
AlanB, 09/30/2022
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A)
I have a new 2022 but the exhaust noise and corresponding vibration in the pedals and steering wheel is very annoying. Test drove another new 2022 today that did not have these issues. After two visits, a total of 11 days in the shop, and replacement of several parts the issue remains and Lexus has now washed their hands and told me that’s just too bad. It’s operating as intended in … their words, but obviously not, or they would not have worked on it two times and replaced parts. Very disappointed in Lexus quality and there their response to customer issues. If they don’t deal with this in a better fashion, they can put me down as a never again customer, and I warn everyone looking at ANY RX 350 to carefully check for this issue. All you have to do is leave the car in park, and very slowly rev the engine between idle and about 2000 RPM . If you hear any abnormal, droning , rumbling or vibrations run from the car, because Lexus will not fix it!
Used 2022 Lexus RX 350 in Des Moines, IA Values
Estimated values
2022 Lexus RX 350 4dr SUV (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $31,859 | $33,685 | $35,590 |
| Clean | $31,435 | $33,219 | $35,078 |
| Average | $30,727 | $32,441 | $34,225 |
| Rough | $29,807 | $31,430 | $33,116 |
The average list price of a used 2022 Lexus RX 350 in Des Moines, Iowa is $39,706. The average mileage on a used Lexus RX 350 2022 for sale in Des Moines, Iowa is 45,994. Based on the average mileage of 45,994 for used 2022 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Des Moines, Iowa to be $30,727.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.