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1,523 listings
    • 29,661 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Walser Auto Campus (329 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Wichita, KS / 329 miles away from Des Moines, IA

    2021 Lexus RX 350, located at Lexus of Wichita. Original MSRP $55,070. Atomic Silver with Black Leather interior. This RX is equipped with the Premium...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA5MC187802
    Stock: 54L1142P
    Certified Pre-Owned: No
    Listed since: 07-30-2025

    • 23,782 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • Bergstrom Auto (344 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Green Bay, WI / 344 miles away from Des Moines, IA

    * Carfax One Owner * Apple Carplay/Android Auto * Power Liftgate * Rear Backup Camera * Keyless Entry * Lexus Certified Certified. L/Certified Details...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3PC032602
    Stock: I5200
    Certified Pre-Owned: No
    Listed since: 05-21-2025

    • 17,313 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 22 City / 29 Hwy MPG
    • Lexus of Louisville (488 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Louisville, KY / 488 miles away from Des Moines, IA

    2023 Lexus RX 350 Clean CARFAX. **ACCIDENT FREE CARFAX**, **BLUETOOTH**, **CARFAX ONE OWNER**, **ELECTRONIC STABILITY CONTROL**, **HEATED MIRRORS**, *...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA6PC008991
    Stock: S043148A
    Certified Pre-Owned: Yes
    Listed since: 08-16-2025

    • 33,090 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • BMW of Omaha (132 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Omaha, NE / 132 miles away from Des Moines, IA

    This OPEN ROAD CERTIFIED 2023 Lexus RX RX 350 Luxury, has a Caviar exterior and an Black w/Black Open Pore interior color. 33,090 miles. Stock Number ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA5PC013601
    Stock: X03696A
    Certified Pre-Owned: No
    Listed since: 07-12-2025

    • 33,434 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • Mungenast Lexus of St Louis (266 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Manchester, MO / 266 miles away from Des Moines, IA

    L/CERTIFIED, Navigation, Bluetooth Handsfree Link, Backup Camera, Power Sunroof, Intuitive Parking Assist, Blind Spot Monitoring, Lexus Safety System+...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA9PC008496
    Stock: P1474
    Certified Pre-Owned: Yes
    Listed since: 08-22-2025

    • 27,430 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • Bergstrom Auto (344 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Green Bay, WI / 344 miles away from Des Moines, IA

    * Carfax One Owner * Apple Carplay/Android Auto * Heated Seats * Rear Backup Camera * Power Moonroof * Lexus Certified Certified. L/Certified Details:...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA6PC015518
    Stock: 250531A
    Certified Pre-Owned: No
    Listed since: 08-29-2025

    • 27,020 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 22 City / 29 Hwy MPG
    • City Auto Memphis (486 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Memphis, TN / 486 miles away from Des Moines, IA

    Vehicle DetailsDiscover the exceptional quality and sophisticated design of the 2023 Lexus RX 350 Premium. This luxury SUV boasts 27,020 miles...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA4PC015213
    Stock: 510872
    Certified Pre-Owned: No
    Listed since: 06-12-2025

  • Price Drop
    • 31,148 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 21 City / 28 Hwy MPG
    • Unlimited Motors Noblesville (410 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Noblesville, IN / 410 miles away from Des Moines, IA

    AWD, Back Up Camera, Bluetooth, Heated Seats, Navigation/GPS, Sun/Moon Roof, Push Button Start, Memory Seats, Keyless entry, and much more ..., Touch ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA4PC020197
    Stock: STK020197
    Certified Pre-Owned: No
    Listed since: 08-29-2025

  • New Listing
    • 29,918 miles
    • No accidents, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • Jay Wolfe Acura of Overland Park (188 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Overland Park, KS / 188 miles away from Des Moines, IA

    RX 350 Premium Plus, 2.4L I4 PDI Turbocharged DOHC 16V LEV3-SULEV30 275hp, AWD, Balance of factory warranty still applies**, Electronic Stability Cont...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA8PC025693
    Stock: K05216A
    Certified Pre-Owned: No
    Listed since: 09-19-2025

    • 34,502 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Bergstrom Auto (344 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Green Bay, WI / 344 miles away from Des Moines, IA

    Recent Arrival! 2021 Lexus RX 350 CARFAX One-Owner. Clean CARFAX. AWD 3.5L V6 DOHC 24V Odometer is 21607 miles below market average! 19/26 City/Highwa...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2JZMDA0MC300486
    Stock: 250543A
    Certified Pre-Owned: No
    Listed since: 08-27-2025

    • 10,780 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • CarMax Hillside (Eisenhower Expy) (296 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Hillside, IL / 296 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA5PC032228
    Stock: 26950056
    Certified Pre-Owned: No

  • Stock photo**
    • 21,541 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • Walser Auto Campus (329 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wichita, KS / 329 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7PC035230
    Stock: 54L1375T
    Certified Pre-Owned: No
    Listed since: 09-17-2025

  • New Listing
    Stock photo**
    • 27,490 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 21 City / 28 Hwy MPG
    • Walser Auto Campus (329 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wichita, KS / 329 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA4PC003304
    Stock: 54L1005LR
    Certified Pre-Owned: No
    Listed since: 09-19-2025

  • Price Drop
    $32,933
    great price
    $4,837 below market
    • 80,188 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Ames Ford Lincoln (28 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Ames, IA / 28 miles away from Des Moines, IA

    1-Owner 2022 Lexus RX350 F Sport that was owned locally and is in very good condition.The following was completed during our multipoint inspection:- R...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2SZMDA4NC362432
    Stock: 55604X
    Certified Pre-Owned: No
    Listed since: 05-15-2025

    • 30,279 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Fields Lexus Glenview (302 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Glenview, IL / 302 miles away from Des Moines, IA

    Just in! This CARFAX one-owner, SUPER LOW MILEAGE, Black / Black RX350 AWD! Perfectly equipped; with premium and cold area packages, power moonroof, A...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA6MC267668
    Stock: L251348A
    Certified Pre-Owned: Yes
    Listed since: 09-05-2025

  • Price Drop
    • 31,976 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Orland (300 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Orland Park, IL / 300 miles away from Des Moines, IA

    Certified. Caviar 2023 Lexus RX 350 Premium Plus AWD 8-Speed Automatic 2.4L I4 PDI Turbocharged DOHC 16V LEV3-SULEV30 275hp BOUGHT HERE SERVICED HERE!...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCAXPC020205
    Stock: PB78661
    Certified Pre-Owned: Yes
    Listed since: 08-22-2025

  • Price Drop
    $40,590
    good price
    $2,825 below market
    • 25,372 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Atlanta, GA / 736 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA8NC250134
    Stock: 2004015902
    Certified Pre-Owned: No
    Listed since: 09-04-2025

  • New Listing
    Stock photo**
    • 15,073 miles
    • 5 Seats, 21 City / 28 Hwy MPG
    • Fields Lexus Glenview (302 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Glenview, IL / 302 miles away from Des Moines, IA

    CARFAX One-Owner. Odometer is 12094 miles below market average!Certified. L/Certified Details: * CERTIFIED WARRANTY: Unlimited-mileage warranty u...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA8PC008862
    Stock: L251030A
    Certified Pre-Owned: Yes
    Listed since: 09-22-2025

  • New Listing
    Stock photo**
    • 20,018 miles
    • 5 Seats, 21 City / 28 Hwy MPG
    • Woodfield Lexus (288 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Schaumburg, IL / 288 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA0PC030046
    Stock: Q3696
    Certified Pre-Owned: No
    Listed since: 09-23-2025

  • $40,333
    great price
    $5,038 below market
    • 31,195 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Old Orchard Nissan (304 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Skokie, IL / 304 miles away from Des Moines, IA

    2022 Lexus RX 8-Speed Automatic AWD, Circuit Red Artificial Leather, 12.3" Navigation System, Auto Recirculation Air Conditioner, F SPORT Handling Pac...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA2NC313689
    Stock: Z2384
    Certified Pre-Owned: No
    Listed since: 12-31-2024

  • New Listing
    Stock photo**
    • 21,258 miles
    • 5 Seats, 21 City / 28 Hwy MPG
    • Woodfield Lexus (288 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Schaumburg, IL / 288 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA5PC016093
    Stock: Q3697
    Certified Pre-Owned: No
    Listed since: 09-23-2025

Showing 127 - 147 out of 1,523 listings

Consumer Reviews for the Lexus RX 350

Read recent reviews for the Lexus RX 350
Overall Consumer Rating
4.2 out of 5 stars44 Reviews
Write a vehicle reviewSee all 44 reviews
  • 5 star
    (66%)
  • 4 star
    (11%)
  • 3 star
    (7%)
  • 2 star
    (5%)
  • 1 star
    (11%)
1 out of 5 stars

Exhaust drones/vibrates between 1400/1900 RPM

AlanB, 09/30/2022
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A)
I have a new 2022 but the exhaust noise and corresponding vibration in the pedals and steering wheel is very annoying. Test drove another new 2022 today that did not have these issues. After two visits, a total of 11 days in the shop, and replacement of several parts the issue remains and Lexus has now washed their hands and told me that’s just too bad. It’s operating as intended in … their words, but obviously not, or they would not have worked on it two times and replaced parts. Very disappointed in Lexus quality and there their response to customer issues. If they don’t deal with this in a better fashion, they can put me down as a never again customer, and I warn everyone looking at ANY RX 350 to carefully check for this issue. All you have to do is leave the car in park, and very slowly rev the engine between idle and about 2000 RPM . If you hear any abnormal, droning , rumbling or vibrations run from the car, because Lexus will not fix it!
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Used 2021 Lexus RX 350 in Des Moines, IA Values

Estimated values
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$31,558$33,794$36,033
Clean$31,065$33,258$35,452
Average$30,243$32,363$34,483
Rough$29,175$31,201$33,223

The average list price of a used 2021 Lexus RX 350 in Des Moines, Iowa is $49,090. The average mileage on a used Lexus RX 350 2021 for sale in Des Moines, Iowa is 28,689. Based on the average mileage of 28,689 for used 2021 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2021 in Des Moines, Iowa to be $30,243.

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