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1,513 listings
- 51,183 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Zimmerman Honda (165 mi away)
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Located in Moline, IL / 165 miles away from Des Moines, IA
*Take a look at this good looking 2022 Lexus RX 350 AWD!* Fully powered with seat memory, integrated navigation, AM/FM stereo, satellite radio, USB, b...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5NC333550
Stock: S1114C
Certified Pre-Owned: No
Listed since: 09-10-2025- 73,590 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Bergstrom Auto (344 mi away)
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Located in Green Bay, WI / 344 miles away from Des Moines, IA
Recent Arrival! 2022 Lexus RX 350 CARFAX One-Owner. Clean CARFAX. Eminent White Pearl AWD 3.5L V6 DOHC 24V 19/26 City/Highway MPG Bergstrom Lexus of A...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC332792
Stock: 250549A
Certified Pre-Owned: No
Listed since: 08-29-2025- 49,852 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (288 mi away)
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Located in Schaumburg, IL / 288 miles away from Des Moines, IA
**ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, ** Local Trade**, **Lexus Safety System Plus**, ** Lane De...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2AZMDA6NC318945
Stock: 251364A
Certified Pre-Owned: Yes
Listed since: 07-31-2025- 52,348 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Victory Toyota of St. Louis (274 mi away)
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Located in Saint Louis, MO / 274 miles away from Des Moines, IA
This **luxurious** 2022 Lexus RX 350 with **52k miles** was a **privately acquired vehicle** here at Victory Toyota St. Louis. Known for its refined r...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC349793
Stock: 86E09501
Certified Pre-Owned: No
Listed since: 09-05-2025- Price Drop
- 42,770 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Brookfield (297 mi away)
- Five Star Dealer
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Located in Brookfield, WI / 297 miles away from Des Moines, IA
**L/Certified** Clean CARFAX. CARFAX One-Owner. Certified. Caviar 2022 Lexus RX 350 8-Speed Automatic AWDColor Head Up Display!Luxury Package!Pa...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2JZMDAXNC342634
Stock: 28749A
Certified Pre-Owned: Yes
Listed since: 09-12-2025 - Price Drop
- 60,440 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Brookfield (297 mi away)
- Five Star Dealer
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Located in Brookfield, WI / 297 miles away from Des Moines, IA
**L/Certified** Clean CARFAX. CARFAX One-Owner. Ultra White 2022 Lexus RX 350 F Sport Handling 8-Speed Automatic AWD19/26 City/Highway MPGCold Wea...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA8NC322431
Stock: PWS2818
Certified Pre-Owned: No
Listed since: 09-15-2025 - New ListingNot Priced
- 33,804 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Highland Park (301 mi away)
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Located in Highland Park, IL / 301 miles away from Des Moines, IA
2022 Lexus RX 350 Silver AWD 3.5L V6 DOHC 24VOur process of Lexus Complete offers a seamless buying experience with upfront pricing and a single po...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC368367
Stock: 251026A
Certified Pre-Owned: No
Listed since: 09-22-2025 - 45,270 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Patriot Chrysler Dodge Jeep Ram of Tulsa (398 mi away)
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Located in Tulsa, OK / 398 miles away from Des Moines, IA
GREAT PRICE ALERT!! Welcome to Patriot CDJR of Tulsa! We are here to provide the absolute best selection, best prices, and best service in Oklahoma!! ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC339616
Stock: PTTM293
Certified Pre-Owned: No
Listed since: 08-20-2025- New Listing
- 41,712 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (288 mi away)
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Located in Schaumburg, IL / 288 miles away from Des Moines, IA
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDAXNC357414
Stock: Q3695
Certified Pre-Owned: No
Listed since: 09-23-2025 - Price Drop$43,999great price$3,535 below market
- 47,802 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Maplewood (240 mi away)
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Located in Maplewood, MN / 240 miles away from Des Moines, IA
L/Certified by Lexus, CarFax One Owner and No Accidents, AWD, Apple CarPlay, Android Auto, Heated and Ventilated Front Seats, Heated Steering Wheel, P...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA4PC035427
Stock: RSL291234A
Certified Pre-Owned: Yes
Listed since: 07-30-2025 - New ListingNot Priced
- 36,157 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Walser Auto Campus (329 mi away)
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Located in Wichita, KS / 329 miles away from Des Moines, IA
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC322140
Stock: 54L1006LR
Certified Pre-Owned: No
Listed since: 09-22-2025 - New Listing$42,995fair price$39 above market
- 62,363 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Baha Auto (305 mi away)
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Located in Chicago, IL / 305 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA4NC317551
Stock: N23024
Certified Pre-Owned: No - $43,499great price$3,653 below market
- 14,380 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Brookfield (297 mi away)
- Five Star Dealer
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Located in Brookfield, WI / 297 miles away from Des Moines, IA
Cold Weather Package!F Sport!12.3" Touchscreen Navigation!Color Heads Up Display!**L/Certified** CARFAX One-Owner. Certified. Ultra White 2021...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA4MC283356
Stock: 28522A
Certified Pre-Owned: Yes
Listed since: 08-22-2025 - $48,900good price$3,820 below market
- 20,570 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 22 City / 29 Hwy MPG
- Volkswagen of Downtown Chicago (310 mi away)
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Located in Chicago, IL / 310 miles away from Des Moines, IA
Our One Owner 2023 Lexus RX 350 Premium is engineered to invoke impressive power and grace in Caviar! Powered by a TurboCharged 2.4 Liter 4 Cylinder o...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
25 Combined MPG (22 City/29 Highway)
Listing Information:
VIN: 2T2BAMBA5PC001255
Stock: 1255K
Certified Pre-Owned: No
Listed since: 08-26-2025 - $49,999good price$3,462 below market
- 13,956 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 21 City / 28 Hwy MPG
- Rosen Hyundai of Algonquin (275 mi away)
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Located in Algonquin, IL / 275 miles away from Des Moines, IA
Priced below KBB Fair Purchase Price! Iridium 2023 Lexus RX 350 F Sport Handling AWD 8-Speed Automatic 2.4L I4 PDI Turbocharged DOHC 16V LEV3-SULEV30 ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA7PC009226
Stock: Q37452A
Certified Pre-Owned: No
Listed since: 07-19-2025 - 63,455 miles
- No accidents, 1 owner, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Baha Auto (301 mi away)
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Located in Palos Hills, IL / 301 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5NC339306
Stock: S32019
Certified Pre-Owned: No- $49,910good price$2,603 below market
- 12,195 miles
- No accidents, 2 owners, rental vehicle
- 5 Seats, 21 City / 28 Hwy MPG
- Mungenast Lexus of St Louis (266 mi away)
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Located in Manchester, MO / 266 miles away from Des Moines, IA
L/CERTIFIED, Navigation, Bluetooth Handsfree Link, Backup Camera, Power Sunroof, Intuitive Parking Assist, Blind Spot Monitoring, Lexus Safety System+...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA9PC032846
Stock: P1414
Certified Pre-Owned: Yes
Listed since: 07-02-2025 - Price Drop$50,555good price$2,876 below market
- 10,094 miles
- No accidents, 2 owners, personal use
- 5 Seats, 22 City / 29 Hwy MPG
- BMW of Louisville (488 mi away)
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Located in Louisville, KY / 488 miles away from Des Moines, IA
2023 Lexus RX 350 Caviar Odometer is 16619 miles below market average! Clean CARFAX.Palomino w/Ash Bamboo w/Leather Seat Trim, Cold Area Package, Navi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
25 Combined MPG (22 City/29 Highway)
Listing Information:
VIN: JTJCHMAA4P2004004
Stock: PJ61247A
Certified Pre-Owned: No
Listed since: 07-18-2025 - $57,000good price$3,332 below market
- 25,328 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Louisville (488 mi away)
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Located in Louisville, KY / 488 miles away from Des Moines, IA
2023 Lexus RX 350 Luxury Clean CARFAX. CARFAX One-Owner. **ACCIDENT FREE CARFAX**, **BLUETOOTH**, **CARFAX ONE OWNER**, **ELECTRONIC STABILITY CONTROL...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA8PC010420
Stock: S046956A
Certified Pre-Owned: Yes
Listed since: 09-01-2025 - $46,000good price$1,417 below market
- 34,341 miles
- No accidents, 1 owner, personal use
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Highland Park (301 mi away)
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Located in Highland Park, IL / 301 miles away from Des Moines, IA
Experience refined luxury and confidence on the road with this L/Certified 2023 Lexus RX 350 Premium AWD, showing just 34,341 miles. Backed by a clean...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA8PC011499
Stock: 250717A
Certified Pre-Owned: Yes
Listed since: 08-05-2025 - $55,490fair price$157 below market
- 29,606 miles
- No accidents, 1 owner, personal use
- 5 Seats, 21 City / 28 Hwy MPG
- McGrath Lexus of Chicago (308 mi away)
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Located in Chicago, IL / 308 miles away from Des Moines, IA
Recent Arrival! Eminent White Pearl 2023 Lexus RX 350 Luxury **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERV...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA3PC030932
Stock: U4782
Certified Pre-Owned: Yes
Listed since: 08-12-2025
Showing 64 - 84 out of 1,513 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Exhaust drones/vibrates between 1400/1900 RPM
AlanB, 09/30/2022
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A)
I have a new 2022 but the exhaust noise and corresponding vibration in the pedals and steering wheel is very annoying. Test drove another new 2022 today that did not have these issues. After two visits, a total of 11 days in the shop, and replacement of several parts the issue remains and Lexus has now washed their hands and told me that’s just too bad. It’s operating as intended in … their words, but obviously not, or they would not have worked on it two times and replaced parts. Very disappointed in Lexus quality and there their response to customer issues. If they don’t deal with this in a better fashion, they can put me down as a never again customer, and I warn everyone looking at ANY RX 350 to carefully check for this issue. All you have to do is leave the car in park, and very slowly rev the engine between idle and about 2000 RPM . If you hear any abnormal, droning , rumbling or vibrations run from the car, because Lexus will not fix it!
Used 2022 Lexus RX 350 in Des Moines, IA Values
Estimated values
2022 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $33,433 | $35,566 | $37,788 |
| Clean | $32,988 | $35,073 | $37,245 |
| Average | $32,245 | $34,252 | $36,340 |
| Rough | $31,280 | $33,184 | $35,162 |
The average list price of a used 2022 Lexus RX 350 in Des Moines, Iowa is $45,635. The average mileage on a used Lexus RX 350 2022 for sale in Des Moines, Iowa is 39,106. Based on the average mileage of 39,106 for used 2022 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Des Moines, Iowa to be $32,245.
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