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1,525 listings
- $42,999fair price$655 above market
- 41,919 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wayzata (234 mi away)
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Located in Wayzata, MN / 234 miles away from Des Moines, IA
Lexus Certified Pre-Owned — Exceptional Quality, Unmatched Peace of MindEvery Lexus Certified Pre-Owned vehicle undergoes a comprehensive 161-point i...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC347436
Stock: PRS505
Certified Pre-Owned: Yes
Listed since: 08-29-2025 - $36,958fair price$257 above market
- 60,675 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Carlson Toyota (250 mi away)
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Located in Coon Rapids, MN / 250 miles away from Des Moines, IA
Introducing the 2022 Lexus RX 350, a luxurious and sophisticated SUV that embodies elegance, performance, and cutting-edge technology. This exceptiona...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC337057
Stock: P11810
Certified Pre-Owned: No
Listed since: 07-15-2025 - $41,988fair price$4 below market
- 50,506 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (308 mi away)
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Located in Chicago, IL / 308 miles away from Des Moines, IA
Recent Arrival! Nightfall Mica 2022 Lexus RX 350 **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES, **APPL...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC356143
Stock: S1615A
Certified Pre-Owned: Yes
Listed since: 08-18-2025 - New Listing$40,998fair price$1,230 above market
- 45,640 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Hillside (Eisenhower Expy) (296 mi away)
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Located in Hillside, IL / 296 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC318912
Stock: 27628054
Certified Pre-Owned: No - $29,555fair price$93 above market
- 120,500 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- BMW of Louisville (488 mi away)
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Located in Louisville, KY / 488 miles away from Des Moines, IA
2022 Lexus RX 350 F Sport Caviar CARFAX One-Owner. Clean CARFAX.AWD, Black Artificial Leather. 19/26 City/Highway MPGBMW of Louisville is Louisville's...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA3NC351566
Stock: P351566
Certified Pre-Owned: No
Listed since: 07-15-2025 - New Listing$40,994fair price$215 below market
- 50,807 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Napleton Hyundai of Carmel (410 mi away)
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Located in Indianapolis, IN / 410 miles away from Des Moines, IA
Recent Arrival! CARFAX One-Owner. Gray 2022 Lexus RX 4D Sport Utility 350 F Sport 3.5L V6 DOHC 24V AWD 8-Speed Automatic Clean CARFAX.AWD, Red Artific...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA3NC309480
Stock: HRS5945
Certified Pre-Owned: No
Listed since: 09-17-2025 - Price Drop$44,230fair price$526 above market
- 31,082 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (266 mi away)
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Located in Manchester, MO / 266 miles away from Des Moines, IA
L/CERTIFIED, Bluetooth Handsfree Link, Leather Seats, Backup Camera, Power Sunroof, Heated/Ventilated seats, Premium Package, Intuitive Parking Assist...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA7NC338779
Stock: 35564A
Certified Pre-Owned: Yes
Listed since: 08-15-2025 - Price Drop$40,301fair price$269 above market
- 60,898 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Burnsville Toyota (218 mi away)
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Located in Burnsville, MN / 218 miles away from Des Moines, IA
NAVIGATION SYSTEM*, *AWD*, *CRUISE CONTROL*, *HARD TO FIND*, *HEATED FRONT SEATS*, LEATHER SEATS*, MOONROOF*, ALLOY WHEELS*, BLUETOOTH*, 3.5L V6 DOHC ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC342985
Stock: 1036761
Certified Pre-Owned: No
Listed since: 08-20-2025 - Price Drop
- 53,935 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Burnsville Toyota (218 mi away)
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Located in Burnsville, MN / 218 miles away from Des Moines, IA
*CRUISE CONTROL*, *HEATED FRONT SEATS*, LEATHER SEATS*, BACKUP CAMERA*, MOONROOF*, ALLOY WHEELS*, BLUETOOTH*, RX 350, AWD. CARFAX One-Owner.2022 Lex...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5NC344399
Stock: 1036675
Certified Pre-Owned: No
Listed since: 08-05-2025 - Price Drop$41,698fair price$1,491 above market
- 42,770 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Brookfield (297 mi away)
- Five Star Dealer
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Located in Brookfield, WI / 297 miles away from Des Moines, IA
**L/Certified** Clean CARFAX. CARFAX One-Owner. Certified. Caviar 2022 Lexus RX 350 8-Speed Automatic AWDColor Head Up Display!Luxury Package!Pa...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2JZMDAXNC342634
Stock: 28749A
Certified Pre-Owned: Yes
Listed since: 09-12-2025 - $39,992fair price$1,008 above market
- 69,576 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Brookfield (297 mi away)
- Five Star Dealer
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Located in Brookfield, WI / 297 miles away from Des Moines, IA
**L/Certified** Clean CARFAX. CARFAX One-Owner. Certified. Caviar 2022 Lexus RX 350 8-Speed Automatic AWDPanorama Moonroof!Heated and Ventilated S...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC337381
Stock: PWS2809
Certified Pre-Owned: Yes
Listed since: 09-03-2025 - Price Drop
- 27,267 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Burnsville Toyota (218 mi away)
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Located in Burnsville, MN / 218 miles away from Des Moines, IA
*CLEAN 1-OWNER CARFAX*, *CRUISE CONTROL*, *HEATED FRONT SEATS*, LEATHER SEATS*, BACKUP CAMERA*, MOONROOF*, ALLOY WHEELS*, BLUETOOTH*, RX 350, AWD. Cle...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3NC363159
Stock: 1036705
Certified Pre-Owned: No
Listed since: 08-15-2025 - Price Drop
- 63,755 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Brookfield (297 mi away)
- Five Star Dealer
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Located in Brookfield, WI / 297 miles away from Des Moines, IA
**L/Certified** Clean CARFAX. Caviar 2022 Lexus RX 350 F Sport Handling 8-Speed Automatic AWDCold Weather Package!Mark Levinson Premium Sound!12...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA4NC309126
Stock: PWS2760A
Certified Pre-Owned: Yes
Listed since: 08-15-2025 - New Listing
- 27,673 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Orland (300 mi away)
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Located in Orland Park, IL / 300 miles away from Des Moines, IA
Eminent White Pearl 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V NAVIGATION!, BOUGHT HERE SERVICED HERE!, LOCAL TRADE!, ONE OWNER!, GREAT ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3NC318366
Stock: PB7884
Certified Pre-Owned: Yes
Listed since: 09-17-2025 - Price Drop$40,990fair price$588 above market
- 42,928 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Unlimited Motors Noblesville (410 mi away)
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Located in Noblesville, IN / 410 miles away from Des Moines, IA
4x4, AWD, Back Up Camera, Bluetooth, Heated Seats, Sun/Moon Roof, Push Button Start, and much more ..., Touch Screen, RX 350 F Sport, 4D Sport Utility...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDAXNC355503
Stock: STK355503
Certified Pre-Owned: No
Listed since: 08-22-2025 - New Listing
- 23,948 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Waukesha (296 mi away)
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Located in Waukesha, WI / 296 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA0NC332456
Stock: 27346918
Certified Pre-Owned: No - 26,002 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Ray Skillman Mazda West (405 mi away)
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Located in Indianapolis, IN / 405 miles away from Des Moines, IA
Silver 2022 Lexus RX 350 F Sport Handling
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDAXNC354006
Stock: JJ2444
Certified Pre-Owned: No
Listed since: 06-05-2025- New Listing
- 32,440 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Walser Polar Mazda (242 mi away)
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Located in White Bear Lake, MN / 242 miles away from Des Moines, IA
At Walser, you’ll get an exceptional car-buying experience. Our *streamlined process* means you’ll work with one dedicated customer specialist to help...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC354353
Stock: 23M1668T
Certified Pre-Owned: No
Listed since: 09-19-2025 - 29,707 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Inver Grove Toyota (229 mi away)
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Located in Inver Grove Heights, MN / 229 miles away from Des Moines, IA
Caviar 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24VRecent Arrival! 19/26 City/Highway MPG
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2AZMDA9NC335948
Stock: A14683
Certified Pre-Owned: No
Listed since: 07-07-2025- 59,654 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Fields Lexus Glenview (302 mi away)
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Located in Glenview, IL / 302 miles away from Des Moines, IA
CARFAX One-Owner. Clean CARFAX.Certified. L/Certified Details: * Vehicle History * Warranty Deductible: $0 * CERTIFIED WARRANTY: Unlimited-mi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDAXNC326003
Stock: P1785
Certified Pre-Owned: Yes
Listed since: 08-18-2025- New Listing
- 38,186 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Springfield (242 mi away)
Close
Located in Springfield, IL / 242 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA8NC342646
Stock: 27243236
Certified Pre-Owned: No
Showing 43 - 63 out of 1,525 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Exhaust drones/vibrates between 1400/1900 RPM
AlanB, 09/30/2022
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A)
I have a new 2022 but the exhaust noise and corresponding vibration in the pedals and steering wheel is very annoying. Test drove another new 2022 today that did not have these issues. After two visits, a total of 11 days in the shop, and replacement of several parts the issue remains and Lexus has now washed their hands and told me that’s just too bad. It’s operating as intended in … their words, but obviously not, or they would not have worked on it two times and replaced parts. Very disappointed in Lexus quality and there their response to customer issues. If they don’t deal with this in a better fashion, they can put me down as a never again customer, and I warn everyone looking at ANY RX 350 to carefully check for this issue. All you have to do is leave the car in park, and very slowly rev the engine between idle and about 2000 RPM . If you hear any abnormal, droning , rumbling or vibrations run from the car, because Lexus will not fix it!
Used 2022 Lexus RX 350 in Des Moines, IA Values
Estimated values
2022 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $32,395 | $34,518 | $36,731 |
| Clean | $31,964 | $34,040 | $36,203 |
| Average | $31,244 | $33,243 | $35,323 |
| Rough | $30,309 | $32,207 | $34,179 |
The average list price of a used 2022 Lexus RX 350 in Des Moines, Iowa is $42,566. The average mileage on a used Lexus RX 350 2022 for sale in Des Moines, Iowa is 47,613. Based on the average mileage of 47,613 for used 2022 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Des Moines, Iowa to be $31,244.
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