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1,525 listings
- Price Drop$38,899good price$1,603 below market
- 46,277 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Unlimited Motors Noblesville (410 mi away)
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Located in Noblesville, IN / 410 miles away from Des Moines, IA
4x4, AWD, Back Up Camera, Bluetooth, Heated Seats, Navigation/GPS, Sun/Moon Roof, Push Button Start, and much more ..., Touch Screen, RX 350, 4D Sport...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC326978
Stock: STK326978
Certified Pre-Owned: No
Listed since: 08-28-2025 - $35,690good price$1,634 below market
- 80,453 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (308 mi away)
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Located in Chicago, IL / 308 miles away from Des Moines, IA
Recent Arrival! Caviar 2022 Lexus RX 350 **APPLE CARPLAY & ANDROID AUTO, **NAVIGATION, **HEATED & COOLED SEATS, **HEATED STEERING WHEEL, **SUNROOF/MOO...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC368000
Stock: S1120B
Certified Pre-Owned: No
Listed since: 06-28-2025 - $37,541fair price$616 below market
- 61,897 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Biggers Mazda (279 mi away)
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Located in Elgin, IL / 279 miles away from Des Moines, IA
🚗 THE BIGGERS PROMISE! ✔ 100% TRANSPARENT PROCESS! ✔ NO JUNK FEES OR EXTRAS!! ✔ NO LAST-MINUTE PRICE ADD-ONS! ✔ NO SURPRISES — EVER! ✔ NO GAMES, JUST...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC335074
Stock: PMB1020
Certified Pre-Owned: No
Listed since: 07-03-2025 - $32,025good price$1,265 below market
- 101,498 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Patriot Chrysler Dodge Jeep Ram of Tulsa (398 mi away)
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Located in Tulsa, OK / 398 miles away from Des Moines, IA
GREAT PRICE ALERT!! Welcome to Patriot CDJR of Tulsa! We are here to provide the absolute best selection, best prices, and best service in Oklahoma!! ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA4NC233637
Stock: PTDP056
Certified Pre-Owned: No
Listed since: 07-15-2025 - Price Drop$42,999fair price$254 below market
- 35,754 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wayzata (234 mi away)
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Located in Wayzata, MN / 234 miles away from Des Moines, IA
Lexus Certified Pre-Owned — Exceptional Quality, Unmatched Peace of MindEvery Lexus Certified Pre-Owned vehicle undergoes a comprehensive 161-point i...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXNC342941
Stock: PRS503
Certified Pre-Owned: Yes
Listed since: 08-27-2025 - 13,506 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (266 mi away)
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Located in Manchester, MO / 266 miles away from Des Moines, IA
L/CERTIFIED, Bluetooth Handsfree Link, Backup Camera, Power Sunroof, Intuitive Parking Assist, Blind Spot Monitoring, Lexus Safety System+, Lexus Enfo...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC327850
Stock: P1463
Certified Pre-Owned: Yes
Listed since: 08-08-2025- New Listing$48,908fair price$83 below market
- 19,279 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Orland (300 mi away)
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Located in Orland Park, IL / 300 miles away from Des Moines, IA
Atomic Silver 2022 Lexus RX 350 AWD 8-Speed Automatic 3.5L V6 DOHC 24V NAVIGATION!, LOCAL TRADE!, ONE OWNER!, GREAT VEHICLE HISTORY!, BACK UP CAMERA, ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC366500
Stock: LX10591
Certified Pre-Owned: Yes
Listed since: 09-19-2025 - Price Drop$44,243fair price$36 above market
- 22,159 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Acura of Westmont (293 mi away)
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Located in Westmont, IL / 293 miles away from Des Moines, IA
Silver 2022 Lexus RX 350 F Sport AWD 8-Speed Automatic 3.5L V6 DOHC 24V. $4035 IN ADDED OPTIONS! **ONE OWNER**, **ACCIDENT FREE CARFAX**, **AWD**, *N...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5NC339886
Stock: PJ12450
Certified Pre-Owned: No
Listed since: 07-18-2025 - New Listing$41,995good price$1,703 below market
- 35,939 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Arlington (292 mi away)
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Located in Arlington Heights, IL / 292 miles away from Des Moines, IA
Discover the ultimate driving experience with this stunning 2022 Lexus RX 350. Boasting a sleek silver exterior and a spacious, well-appointed interio...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXNC362266
Stock: AL4322A
Certified Pre-Owned: No
Listed since: 09-18-2025 - New Listing$37,200good price$1,737 below market
- 70,112 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Milwaukee (310 mi away)
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Located in Milwaukee, WI / 310 miles away from Des Moines, IA
L/Certified Details: * Vehicle History * Limited Warranty: 24 Month/Unlimited Mile * Roadside Assistance * 161 Point Inspection * CERTIFIED...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5NC315751
Stock: L21189A
Certified Pre-Owned: Yes
Listed since: 09-19-2025 - $49,995fair price$1,137 above market
- 31,696 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (288 mi away)
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Located in Schaumburg, IL / 288 miles away from Des Moines, IA
**ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, **Lexus Safety System Plus**, ** Lane Departure Warning, *...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA1NC367680
Stock: Q3689
Certified Pre-Owned: Yes
Listed since: 09-09-2025 - $42,990fair price$554 below market
- 22,033 miles
- 1 accident, 1 owner, corporate fleet vehicle
- 5 Seats, 20 City / 27 Hwy MPG
- Unlimited Motors Westfield (404 mi away)
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Located in Westfield, IN / 404 miles away from Des Moines, IA
Back Up Camera, Bluetooth, Sun/Moon Roof, Heated Seats, Touch Screen, Cooled Heats, Blind Spot, Heated Steering Wheel, RX 350, 4D Sport Utility, 3.5L ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA4NC233248
Stock: STK233248
Certified Pre-Owned: No
Listed since: 08-29-2025 - New Listing$42,291good price$1,647 below market
- 39,133 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Ed Martin Toyota (414 mi away)
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Located in Noblesville, IN / 414 miles away from Des Moines, IA
RX 350 F Sport, 4D Sport Utility, 3.5L V6 DOHC 24V, 8-Speed Automatic, AWD, Ultra White, Circuit Red Artificial Leather.19/26 City/Highway MPGWireless...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA7NC315833
Stock: 621404A
Certified Pre-Owned: No
Listed since: 09-19-2025 - Price Drop$43,887fair price$106 above market
- 36,836 miles
- No accidents, 1 owner, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Serra Chevrolet (487 mi away)
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Located in Bartlett, TN / 487 miles away from Des Moines, IA
AWD. CARFAX One-Owner.AWD, 20 x 8 Aluminum Wheels, 3.33 Axle Ratio, 4-Wheel Disc Brakes, 9 Speakers, ABS brakes, Air Conditioning, Alloy wheels, AM/FM...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA6NC337709
Stock: PNC337709
Certified Pre-Owned: No
Listed since: 07-30-2025 - $43,990fair price$431 above market
- 26,131 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Unlimited Motors Westfield (404 mi away)
Close
Located in Westfield, IN / 404 miles away from Des Moines, IA
Back Up Camera, Bluetooth, Sun/Moon Roof, Heated Seats, Touch Screen, Cooled Heats, Blind Spot, Heated Steering Wheel, RX 350 F Sport, 4D Sport Utilit...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA6NC331683
Stock: STK331683
Certified Pre-Owned: No
Listed since: 08-22-2025 - Price Drop$41,999fair price$1,045 above market
- 30,788 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Tom Kadlec Honda (178 mi away)
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Located in Rochester, MN / 178 miles away from Des Moines, IA
Lexus RX 350 3.5L V6 DOHC 24V Carfax 1 owner, AWD, Parchment Artificial Leather, Air Conditioning, AM/FM/CD Radio, Apple CarPlay/Android Auto, Automat...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3NC344353
Stock: P12157
Certified Pre-Owned: No
Listed since: 09-11-2025 - Price Drop$45,499fair price$493 above market
- 28,365 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wayzata (234 mi away)
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Located in Wayzata, MN / 234 miles away from Des Moines, IA
Recent Arrival! CARFAX One-Owner. Certified. Caviar 2022 Lexus RX 4D Sport Utility 350 3.5L V6 DOHC 24V AWD 19/26 City/Highway MPG Odometer is 4365 mi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC320638
Stock: PRS507
Certified Pre-Owned: Yes
Listed since: 09-09-2025 - $41,984fair price$1,104 above market
- 29,376 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Tom Wood Volkswagen Noblesville (414 mi away)
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Located in Noblesville, IN / 414 miles away from Des Moines, IA
*** SOPHISTICATED LUXURY & STRONG PERFORMANCE IN A MIDSIZE SUV! ***2022 Lexus RX 350 9 Speakers, Apple CarPlay/Android Auto, Compass, Emergency comm...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA9NC228594
Stock: VNI228594
Certified Pre-Owned: No
Listed since: 08-20-2025 - $49,988fair price$1,020 below market
- 12,432 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (308 mi away)
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Located in Chicago, IL / 308 miles away from Des Moines, IA
Recent Arrival! Caviar 2022 Lexus RX 350 F Sport **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES, **APPL...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA4NC368330
Stock: S1777A
Certified Pre-Owned: Yes
Listed since: 09-08-2025 - 30,165 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Jack Schmitt Chevrolet of O'Fallon (285 mi away)
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Located in O Fallon, IL / 285 miles away from Des Moines, IA
Clean CARFAX. Odometer is 5448 miles below market average! This 2022 Lexus RX comes equipped with the following - AWD, 18' x 8' Aluminum Wheels, 3.33 ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC351611
Stock: 16386P
Certified Pre-Owned: No
Listed since: 08-07-2025- New Listing$43,500good price$1,911 below market
- 43,666 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Reliable Superstore (305 mi away)
Close
Located in Springfield, MO / 305 miles away from Des Moines, IA
Recent Arrival! Clean CARFAX. 2022 Lexus RX 350 F Sport Blue 4D Sport Utility 3.5L V6 DOHC 24V 8-Speed Automatic AWD 19/26 City/Highway MPG
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA2NC360940
Stock: NC360940P
Certified Pre-Owned: No
Listed since: 09-22-2025
Showing 22 - 42 out of 1,525 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Exhaust drones/vibrates between 1400/1900 RPM
AlanB, 09/30/2022
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A)
I have a new 2022 but the exhaust noise and corresponding vibration in the pedals and steering wheel is very annoying. Test drove another new 2022 today that did not have these issues. After two visits, a total of 11 days in the shop, and replacement of several parts the issue remains and Lexus has now washed their hands and told me that’s just too bad. It’s operating as intended in … their words, but obviously not, or they would not have worked on it two times and replaced parts. Very disappointed in Lexus quality and there their response to customer issues. If they don’t deal with this in a better fashion, they can put me down as a never again customer, and I warn everyone looking at ANY RX 350 to carefully check for this issue. All you have to do is leave the car in park, and very slowly rev the engine between idle and about 2000 RPM . If you hear any abnormal, droning , rumbling or vibrations run from the car, because Lexus will not fix it!
Used 2022 Lexus RX 350 in Des Moines, IA Values
Estimated values
2022 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $33,357 | $35,543 | $37,822 |
| Clean | $32,913 | $35,051 | $37,278 |
| Average | $32,172 | $34,230 | $36,372 |
| Rough | $31,209 | $33,163 | $35,194 |
The average list price of a used 2022 Lexus RX 350 in Des Moines, Iowa is $42,781. The average mileage on a used Lexus RX 350 2022 for sale in Des Moines, Iowa is 38,928. Based on the average mileage of 38,928 for used 2022 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Des Moines, Iowa to be $32,172.
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