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1,256 listings
    • 18,521 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • Lexus of Knoxville (124 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Knoxville, TN / 124 miles away from Greenville, SC

    Clean CARFAX. **FULLY SERVICED BY A FACTORY TRAINED TECHNICIAN.The Optional Features Included on this are: Premium Package, 12.3 Navigation System, 18...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA7NC239836
    Stock: P12523
    Certified Pre-Owned: No
    Listed since: 08-14-2025

  • Stock photo**
    $41,990
    fair price
    $67 above market
    • 57,627 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • Butler Lexus of South Atlanta (149 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Union City, GA / 149 miles away from Greenville, SC

    **OEM CERTIFIED** Thank you for choosing BUTLER LEXUS OF SOUTH ATLANTA, this Atomic Silver 2022 Lexus RX 350 is a great choice! Check out the followin...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA6NC252500
    Stock: GC8138
    Certified Pre-Owned: Yes
    Listed since: 08-28-2025

    • 21,933 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Lexus of Knoxville (124 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Knoxville, TN / 124 miles away from Greenville, SC

    CARFAX One-Owner. Clean CARFAX. **FULLY SERVICED BY A FACTORY TRAINED TECHNICIAN.The Optional Features Included on this are: Premium Package, 18 x 8 A...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA8NC223967
    Stock: P12521
    Certified Pre-Owned: No
    Listed since: 08-13-2025

  • Price Drop
    $38,900
    fair price
    $1,082 above market
    • 55,928 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • Nalley Lexus Smyrna (135 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Smyrna, GA / 135 miles away from Greenville, SC

    RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2AZMAA8NC235585
    Stock: NLS257468A
    Certified Pre-Owned: Yes
    Listed since: 08-22-2025

  • New Listing
    • 26,328 miles
    • No accidents, 3 owners, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Carvana - Atlanta (136 mi away)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Atlanta, GA / 136 miles away from Greenville, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA3NC330906
    Stock: 2004022988
    Certified Pre-Owned: No
    Listed since: 09-04-2025

  • Price Drop
    • 33,279 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Jim Hudson Toyota Sumter (128 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sumter, SC / 128 miles away from Greenville, SC

    Priced below KBB Fair Purchase Price! Odometer is 1317 miles below market average!AWD, Black Artificial Leather, 12.3" Navigation System, 20" x 8" A...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA1NC352807
    Stock: SP352
    Certified Pre-Owned: No
    Listed since: 08-15-2025

    • 41,546 miles
    • No accidents, 3 owners, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Stokes Hodges Ford (93 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Graniteville, SC / 93 miles away from Greenville, SC

    RX 350, 3.5L V6 DOHC 24V, AWD, Glazed Caramel w/NuLuxe Seat Trim, 12.3" Navigation System, 3500 lbs Tow Prep Package, Auto Recirculation Air Condition...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA8NC339584
    Stock: PC6230
    Certified Pre-Owned: No
    Listed since: 07-14-2025

  • New Listing
    • 27,807 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • Jim Hudson Lexus (93 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Columbia, SC / 93 miles away from Greenville, SC

    L/Certified Details: * Roadside Assistance * Vehicle History * 161 Point Inspection * Limited Warranty: 24 Month/Unlimited Mile * CERTIFIED WARRANTY: ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA8NC231213
    Stock: C35785A
    Certified Pre-Owned: Yes
    Listed since: 09-01-2025

    • 46,635 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 20 City / 27 Hwy MPG
    • Flow Lexus of Greensboro (166 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Greensboro, NC / 166 miles away from Greenville, SC

    The car you've always wanted! Check out this 2022! The more time you spend in this vehicle, the more you'll appreciate the engineering that went into ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA6NC250519
    Stock: 6901A
    Certified Pre-Owned: Yes
    Listed since: 08-15-2025

  • New Listing
    Stock photo**
    $42,998
    fair price
    $1,315 above market
    • 59,117 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • Flow Lexus of Winston Salem (145 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Winston Salem, NC / 145 miles away from Greenville, SC

    You won't want to miss this excellent value! It'll satisfy drivers and passengers seeking the ultimate in comfort and refinement. This vehicle has ach...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTJHZMDA4N2058883
    Stock: 39319A
    Certified Pre-Owned: Yes
    Listed since: 09-02-2025

  • $47,702
    great price
    $6,261 below market
    • 42,164 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 22 City / 29 Hwy MPG
    • Jim Hudson Acura (91 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Augusta, GA / 91 miles away from Greenville, SC

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA2PC006106
    Stock: RM2166A
    Certified Pre-Owned: No
    Listed since: 04-17-2025

  • Price Drop
    • 27,893 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 19 City / 26 Hwy MPG
    • John Hiester Chrysler Dodge Jeep Ram of Sanford (188 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sanford, NC / 188 miles away from Greenville, SC

    ONE OWNER, BALANCE OF FACTORY WARRANTY, LIFETIME ENGINE GUARANTEE, AWD, POWER SUNROOF, FAST AND EASY FINANCING, THE NEW PRICE OUTLET, AWD, Red Artific...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2YZMDA1NC338843
    Stock: 12485U
    Certified Pre-Owned: No
    Listed since: 08-22-2025

    • 57,847 miles
    • 1 accident, 2 owners, personal use
    • 5 Seats, 20 City / 27 Hwy MPG
    • John Miles Chevrolet Buick GMC (122 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Conyers, GA / 122 miles away from Greenville, SC

    *Vehicle Details*Discover the luxury and performance of the 2022 Lexus RX 350 BASE, now available at an unbeatable price. This sophisticated SUV, equi...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2AZMAAXNC226211
    Stock: P6931
    Certified Pre-Owned: No
    Listed since: 08-07-2025

  • Price Drop
    • 83,910 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 19 City / 26 Hwy MPG
    • Harper INFINITI (123 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Knoxville, TN / 123 miles away from Greenville, SC

    Recent Arrival! CARFAX One-Owner. 2022 Lexus RX 350 in Caviar, Premium Package, Wheels: 20" Dark Silver Alloy w/Machined Finish. 19/26 City/Highway MP...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: 2T2HZMDA8NC328228
    Stock: 253701
    Certified Pre-Owned: No
    Listed since: 08-28-2025

  • $53,499
    great price
    $3,533 below market
    • 16,450 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 22 City / 29 Hwy MPG
    • Nalley Lexus Roswell (122 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Roswell, GA / 122 miles away from Greenville, SC

    RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA4PC011453
    Stock: NLRP232467
    Certified Pre-Owned: No
    Listed since: 05-29-2025

  • New Listing
    • 30,271 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 22 City / 29 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Houston, TX / 843 miles away from Greenville, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA5PC006519
    Stock: 2003995954
    Certified Pre-Owned: No
    Listed since: 09-03-2025

  • New Listing
    Stock photo**
    • 32,089 miles
    • 5 Seats, 20 City / 27 Hwy MPG
    • Butler Lexus of South Atlanta (149 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Union City, GA / 149 miles away from Greenville, SC

    **OEM CERTIFIED** Thank you for choosing BUTLER LEXUS OF SOUTH ATLANTA, this 2022 Lexus RX RX 350 is a great choice! Check out the following:City 20/...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA2NC249545
    Stock: GC8148
    Certified Pre-Owned: Yes
    Listed since: 09-04-2025

  • New Listing
    Stock photo**
    • 37,857 miles
    • 5 Seats, 20 City / 27 Hwy MPG
    • Lexus of Knoxville (124 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Knoxville, TN / 124 miles away from Greenville, SC

    **FULLY SERVICED BY A FACTORY TRAINED TECHNICIAN.The Optional Features Included on this are: Premium Package, 12.3 Navigation System, 18 x 8 Aluminum ...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    23 Combined MPG (20 City/27 Highway)

    Listing Information:

    VIN: 2T2HZMAA2NC227593
    Stock: P12540
    Certified Pre-Owned: No
    Listed since: 09-04-2025

  • New Listing
    $42,997
    great price
    $6,113 below market
    • 41,954 miles
    • 5 Seats, 22 City / 29 Hwy MPG
    • EchoPark Automotive (94 mi away)
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Charlotte, NC / 94 miles away from Greenville, SC

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: JTJCHMAA3P2007489
    Stock: PP2007489
    Certified Pre-Owned: No
    Listed since: 07-31-2025

  • New Listing
    Stock photo**
    $51,900
    great price
    $3,788 below market
    • 15,944 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 22 City / 29 Hwy MPG
    • Clark Chevrolet (168 mi away)
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Pinehurst, NC / 168 miles away from Greenville, SC

    2023 LEXUS RX 350 LUXURY***SAVE $$$ NO DOC FEE**CONTACT US TODAY TO CONFIRM AVAILABILITY AND TO GET THIS SPECIAL ONLINE PRICING OR DISCOUNT. WE WI...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA3PC019012
    Stock: 17976A
    Certified Pre-Owned: No
    Listed since: 09-03-2025

  • Price Drop
    $50,990
    good price
    $2,833 below market
    • 6,871 miles
    • No accidents, 1 owner, corporate fleet vehicle
    • 5 Seats, 21 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Sacramento, CA / 2,163 miles away from Greenville, SC

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3PC037413
    Stock: 2003936427
    Certified Pre-Owned: No
    Listed since: 08-04-2025

Showing 85 - 105 out of 1,256 listings

Consumer Reviews for the Lexus RX 350

Read recent reviews for the Lexus RX 350
Overall Consumer Rating
3.3 out of 5 stars72 Reviews
Write a vehicle reviewSee all 72 reviews
  • 5 star
    (39%)
  • 4 star
    (13%)
  • 3 star
    (7%)
  • 2 star
    (18%)
  • 1 star
    (24%)
2 out of 5 stars

Nice interior; terrible engine.

DV, 06/25/2023
2023 Lexus RX 350 Luxury 4dr SUV (2.4L 4cyl Turbo 8A)
The 4 cylinder engines are loud and vibrate a lot.
Report abuse

Used 2022 Lexus RX 350 in Greenville, SC Values

Estimated values
2022 Lexus RX 350 4dr SUV (3.5L 6cyl 8A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$32,744$34,647$36,633
Clean$32,307$34,168$36,107
Average$31,580$33,368$35,229
Rough$30,635$32,328$34,087

The average list price of a used 2022 Lexus RX 350 in Greenville, South Carolina is $45,306. The average mileage on a used Lexus RX 350 2022 for sale in Greenville, South Carolina is 37,237. Based on the average mileage of 37,237 for used 2022 Lexus RX 350 for sale in Greenville, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Greenville, South Carolina to be $31,580.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.