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174 listings
- New Listing$39,995great price$4,927 below market
- 78,627 miles
- 5 Seats, 31 City / 28 Hwy MPG
- BMW of Columbia (193 mi away)
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Located in Columbia, MO / 193 miles away from Des Moines, IA
Recent Arrival! Back Up Camera, Heated Seats, Moonroof, Leather, Carfax One Owner, Head-Up Display, RX 450h, 4D Sport Utility, 3.5L V6 DOHC VVT-i 24V,...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA9NC075914
Stock: B21027A
Certified Pre-Owned: No
Listed since: 09-19-2025 - Price Drop$43,999good price$3,658 below market
- 36,457 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Tom Kadlec Honda (178 mi away)
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Located in Rochester, MN / 178 miles away from Des Moines, IA
Lexus RX 450h 3.5L V6 DOHC VVT-i 24V Carfax 1 owner, Clean Vehicle History Report, 3.5L V6 DOHC VVT-i 24V, AWD, Black Artificial Leather, Apple CarPla...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA5NC086262
Stock: P12129
Certified Pre-Owned: No
Listed since: 08-28-2025 - $44,560fair price$28 below market
- 47,174 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Zeigler Buick GMC of Lincolnwood (306 mi away)
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Located in Lincolnwood, IL / 306 miles away from Des Moines, IA
Recent Arrival! 2022 Lexus RX 450h Black AWD*, 3.5L V6 DOHC VVT-i 24V, AWD. 31/28 City/Highway MPGAt Zeigler Buick GMC of Lincolnwood, we take pride ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA5NC073611
Stock: PA8212
Certified Pre-Owned: No
Listed since: 09-09-2025 - Price Drop$42,211fair price$137 below market
- 39,772 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Audi Creve Couer (263 mi away)
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Located in Creve Coeur, MO / 263 miles away from Des Moines, IA
RECALL NOTICE: Some vehicles offered for sale may be subject to unrepaired manufacturer safety recalls. To determine the recall status of a vehicle, v...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA7NC083606
Stock: PLAP220818
Certified Pre-Owned: No
Listed since: 06-30-2025 - Price Drop$45,999fair price$203 above market
- 19,468 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Tom Kadlec Honda (178 mi away)
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Located in Rochester, MN / 178 miles away from Des Moines, IA
Lexus RX 450h 3.5L V6 DOHC VVT-i 24V Carfax 1 owner, Clean Vehicle History Report, 3.5L V6 DOHC VVT-i 24V, AWD, Black Artificial Leather, Air Conditio...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2NC086834
Stock: P12126
Certified Pre-Owned: No
Listed since: 08-25-2025 - Price Drop$46,990fair price$277 above market
- 20,261 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Unlimited Motors Westfield (404 mi away)
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Located in Westfield, IN / 404 miles away from Des Moines, IA
Back Up Camera, Bluetooth, Sun/Moon Roof, Heated Seats, Touch Screen, Cooled Heats, Blind Spot, Heated Steering Wheel, RX 450h F Sport, 4D Sport Utili...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2SGMDAXNC083993
Stock: STK083993
Certified Pre-Owned: No
Listed since: 07-18-2025 - Price Drop$43,250fair price$913 below market
- 37,087 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Unlimited Motors Elwood (417 mi away)
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Located in Elwood, IN / 417 miles away from Des Moines, IA
Navigation, Back Up Camera, Sunroof, Bluetooth, Touch Screen, Heated Seats, Heated Steering Wheel, Power Lift Gate, Blind Spot, Low Miles, Lane Assist...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA7NC092919
Stock: STK092919
Certified Pre-Owned: No
Listed since: 07-18-2025 - 37,097 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Fields Lexus Glenview (302 mi away)
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Located in Glenview, IL / 302 miles away from Des Moines, IA
JUST IN! This one-owner, clean CARFAX, GORGEOUS, Black / Black RX450H Hybrid AWD! Meticulously maintained and exquisitely equipped, with Luxury, cold ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA0NC083156
Stock: L251293A
Certified Pre-Owned: Yes
Listed since: 09-04-2025- 44,351 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Unlimited Motors Noblesville (410 mi away)
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Located in Noblesville, IN / 410 miles away from Des Moines, IA
4x4, AWD, Back Up Camera, Bluetooth, Heated Seats, Sun/Moon Roof, Push Button Start, and much more ..., Touch Screen, RX 450h, 4D Sport Utility, 3.5L ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2NC084338
Stock: STK084338
Certified Pre-Owned: No
Listed since: 07-28-2025- New ListingNot Priced
- 81,747 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Twins Chrysler Dodge Jeep RAM of Wayland (416 mi away)
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Located in Wayland, MI / 416 miles away from Des Moines, IA
Twins Chrysler Dodge Jeep Ram is proud to offer all new vehicles at ZERO MARKUP to our customers! All new vehicles are priced at or below our cost! Br...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDAXNC076584
Stock: U02040
Certified Pre-Owned: No
Listed since: 09-19-2025 - New Listing$38,995fair price$257 above market
- 63,603 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Arlington (292 mi away)
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Located in Arlington Heights, IL / 292 miles away from Des Moines, IA
Elevate your driving experience with the exceptional 2021 Lexus RX 450h. This captivating SUV combines luxury, performance, and efficiency, making it ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA7MC060891
Stock: AL1192SA
Certified Pre-Owned: No
Listed since: 09-16-2025 - Price Drop
- 49,890 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Walser Toyota (226 mi away)
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Located in Bloomington, MN / 226 miles away from Des Moines, IA
At Walser, you’ll get an exceptional car-buying experience. Our *streamlined process* means you’ll work with one dedicated customer specialist to help...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA4MC058081
Stock: 3T2955T
Certified Pre-Owned: No
Listed since: 09-05-2025 - New Listing$43,590great price$8,528 below market
- 37,221 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
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Located in Las Vegas, NV / 1,214 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA1NC089127
Stock: 2003775711
Certified Pre-Owned: No
Listed since: 05-30-2025 - $44,997great price$5,278 below market
- 20,796 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Old Orchard Nissan (304 mi away)
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Located in Skokie, IL / 304 miles away from Des Moines, IA
2022 Lexus RX eCVT 3.5L V6 DOHC VVT-i 24V, AWD, Black Artificial Leather, 18" Aluminum Wheels, Power driver seat, Power Liftgate, Rain sensing wipers....
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA3NC085756
Stock: T1344
Certified Pre-Owned: No
Listed since: 08-16-2025 - Price Drop$39,545great price$6,385 below market
- 62,077 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Fort Wayne (438 mi away)
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Located in Fort Wayne, IN / 438 miles away from Des Moines, IA
Experience true luxury at Lexus of Fort Wayne. From personalized service to world-class hospitality, your journey to exceptional driving begins here.T...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA6NC089963
Stock: FL1539P
Certified Pre-Owned: Yes
Listed since: 08-02-2025 - $40,300great price$5,735 below market
- 68,600 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Spirit Lexus (264 mi away)
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Located in St. Louis, MO / 264 miles away from Des Moines, IA
Certified. Grecian Water 2022 Lexus RX 450h F Sport AWD eCVT 3.5L V6 DOHC VVT-i 24V ** LOCAL TRADE **, **ANDROID AUTO**, **APPLE CARPLAY**, **AWD**, *...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA0NC076013
Stock: P8N076013
Certified Pre-Owned: Yes
Listed since: 08-09-2025 - New Listing$41,716great price$4,278 below market
- 53,866 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
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Located in Lexington, KY / 550 miles away from Des Moines, IA
Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Lane K...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA3NC088898
Stock: NC088898A
Certified Pre-Owned: No - $45,500good price$4,135 below market
- 52,835 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Lux Cars Chicago (294 mi away)
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Located in Buffalo Grove, IL / 294 miles away from Des Moines, IA
2022 LEXUS RX 450H AWD HYBRID SUV WITH 3.5L V6 HYBRID DRIVE SYSTEM AND CVT TRANSMISSION WITH PADDLE SHIFTERS. SOPHISTICATED NEBULA GRAY PEARL EXTERIOR...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA8NC094776
Stock: 9910
Certified Pre-Owned: No
Listed since: 08-13-2025 - $45,777good price$2,539 below market
- 18,332 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Old Orchard Nissan (304 mi away)
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Located in Skokie, IL / 304 miles away from Des Moines, IA
2022 Lexus RX eCVT 3.5L V6 DOHC VVT-i 24V, AWD, Glazed Caramel Artificial Leather, 12.3" Navigation System, Auto Recirculation Air Conditioner, Driver...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA0NC091028
Stock: B1011
Certified Pre-Owned: No
Listed since: 07-25-2025 - $43,788good price$2,439 below market
- 45,449 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Frank Leta Acura (274 mi away)
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Located in Saint Louis, MO / 274 miles away from Des Moines, IA
Certified! 90 Day/3,000 Mile Limited Comprehensive Warranty and a 7 Year/100,000 Mile Limited Powertrain Warranty! One Owner/CARFAX No Accidents! Comp...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA5NC090120
Stock: PJK2104
Certified Pre-Owned: No
Listed since: 09-06-2025 - New Listing$48,998fair price$171 below market
- 25,397 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from MD to IA*
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Located in Hagerstown, MD / 846 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA7NC093620
Stock: 27751074
Certified Pre-Owned: No
Showing 1 - 21 out of 174 listings
Consumer Reviews for the Lexus RX 450h
Read recent reviews for the Lexus RX 450h
My Atomic Silver Ride!
markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
Used 2022 Lexus RX 450h in Des Moines, IA Values
Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $34,254 | $35,751 | $37,311 |
| Clean | $33,797 | $35,256 | $36,774 |
| Average | $33,037 | $34,430 | $35,880 |
| Rough | $32,048 | $33,357 | $34,718 |
The average list price of a used 2022 Lexus RX 450h in Des Moines, Iowa is $43,975. The average mileage on a used Lexus RX 450h 2022 for sale in Des Moines, Iowa is 44,767. Based on the average mileage of 44,767 for used 2022 Lexus RX 450h for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Des Moines, Iowa to be $33,037.
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