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175 listings
  • New Listing
    $48,998
    fair price
    $113 below market
    • 25,397 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from MD to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Hagerstown, MD / 846 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA7NC093620
    Stock: 27751074
    Certified Pre-Owned: No

  • $47,998
    fair price
    $105 below market
    • 29,195 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from VA to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Roanoke, VA / 784 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5NC090215
    Stock: 27842395
    Certified Pre-Owned: No

  • Price Drop
    $44,988
    fair price
    $1,203 below market
    • 44,536 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Landers Toyota (480 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Little Rock, AR / 480 miles away from Des Moines, IA

    Heated Seats, Moonroof, Nav System, iPod/MP3 Input, Satellite Radio, Hybrid, Power Liftgate, All Wheel Drive, PANORAMIC-VIEW MONITOR W/RR CROSS-TRA. P...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXNC081414
    Stock: C081414L
    Certified Pre-Owned: No
    Listed since: 04-13-2025

  • $44,519
    fair price
    $525 above market
    • 35,187 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Middletown, NY / 992 miles away from Des Moines, IA

    CarFax No Accidents Reported,CarFax 1-Owner,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated S...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA6NC087324
    Stock: NC087324T
    Certified Pre-Owned: No

  • New Listing
    $48,000
    fair price
    $1,847 below market
    • 22,127 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Golden Circle Ford Lincoln (485 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Jackson, TN / 485 miles away from Des Moines, IA

    FREE 20 YEAR / 200,000 MILE POWERTRAIN WARRANTY, ONE OWNER, CLEAN CARFAX, AWD ALL WHEEL DRIVE, BLUETOOTH, SIRIUS XM SATELLITE RADIO, APPLE CARPLAY, GO...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA9NC074180
    Stock: 1574238A
    Certified Pre-Owned: No
    Listed since: 09-17-2025

  • New Listing
    $46,994
    fair price
    $7 below market
    • 18,135 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Van Nuys, CA / 1,440 miles away from Des Moines, IA

    Low Mileage,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Lane...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA3NC092738
    Stock: NC092738T
    Certified Pre-Owned: No

  • $45,795
    fair price
    $1,461 below market
    • 38,950 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • The Car Buying Center (240 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Loretto, MN / 240 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDAXNC088959
    Stock: 088959
    Certified Pre-Owned: No
    Listed since: 09-03-2025

  • Price Drop
    $39,544
    fair price
    $539 above market
    • 68,345 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Tom Roush Lincoln (414 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fishers, IN / 414 miles away from Des Moines, IA

    Nebula Gray Pearl 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V**ONE OWNER**, **NO ACCIDENTS**, **LEATHER SEATS**, **PANORAMIC SUNROOF/MOONROOF**...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4NC083161
    Stock: L25096A
    Certified Pre-Owned: No
    Listed since: 05-31-2025

  • New Listing
    $42,987
    fair price
    $346 above market
    • 62,546 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Portland, OR / 1,476 miles away from Des Moines, IA

    CarFax No Accidents Reported,Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Keyless Start,Lane Keeping...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA7NC075442
    Stock: NC075442P
    Certified Pre-Owned: No

  • New Listing
    $50,998
    fair price
    $832 above market
    • 17,441 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CO to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Colorado Springs, CO / 613 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4NC088830
    Stock: 27630420
    Certified Pre-Owned: No

    • 21,095 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Schoepp Motors Middleton West (235 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Middleton, WI / 235 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4NC079528
    Stock: VIN
    Certified Pre-Owned: No
    Listed since: 06-24-2025

    • 16,924 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from FL to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Ocola, FL / 1,073 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA7NC084481
    Stock: 27496594
    Certified Pre-Owned: No

    • 9,450 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • The Car Buying Center (240 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Loretto, MN / 240 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2NC075462
    Stock: 075462
    Certified Pre-Owned: No
    Listed since: 09-03-2025

  • New Listing
    • 37,207 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Hendrick Lexus Kansas City North (170 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Kansas City, MO / 170 miles away from Des Moines, IA

    2 yr L/ Certified Warranty, UNLIMITED miles, Very well maintained, we have the records to prove it! CARFAX 1-Owner, L/ Certified, Spotless, GREAT MILE...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5NC083670
    Stock: P7695
    Certified Pre-Owned: Yes
    Listed since: 09-18-2025

    • 45,907 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Smart Lexus (158 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Davenport, IA / 158 miles away from Des Moines, IA

    Certified. Caviar 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V For more info. please call TJ Deere Manager 5**-4**-4***, 3.5L V6 DOHC VVT-i 24V,...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA9NC086198
    Stock: L1N086198
    Certified Pre-Owned: No
    Listed since: 01-23-2025

  • New Listing
    • 28,063 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Omaha (131 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Omaha, NE / 131 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA6NC082108
    Stock: L034567A
    Certified Pre-Owned: No
    Listed since: 09-10-2025

  • Price Drop
    $39,998
    fair price
    $664 above market
    • 60,587 miles
    • 1 accident, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from CA to IA*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Costa Mesa, CA / 1,430 miles away from Des Moines, IA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA7NC072492
    Stock: 27769824
    Certified Pre-Owned: No

  • $39,591
    great price
    $5,673 below market
    • 44,164 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Roadshow MINI (492 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Cordova, TN / 492 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA3MC067404
    Stock: 32481H
    Certified Pre-Owned: No
    Listed since: 08-03-2025

  • New Listing
    • 78,854 miles
    • 1 accident, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Lincoln (169 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Lincoln, NE / 169 miles away from Des Moines, IA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA1NC089015
    Stock: ST012713A
    Certified Pre-Owned: No
    Listed since: 09-07-2025

  • $36,724
    good price
    $2,797 below market
    • 91,656 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Hendrick Lexus Kansas City North (170 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Kansas City, MO / 170 miles away from Des Moines, IA

    3 month / 3k mile Hendrick Affordable Warranty, Very well maintained, we have the records to prove it! Originally purchased new from our store. Just t...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDAXMC070588
    Stock: S58662A
    Certified Pre-Owned: No
    Listed since: 09-14-2025

  • New Listing
    $39,990
    great price
    $2,256 below market
    • 53,059 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Sacramento, CA / 1,480 miles away from Des Moines, IA

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDA1MC057409
    Stock: 2004094723
    Certified Pre-Owned: No
    Listed since: 09-20-2025

Showing 22 - 42 out of 175 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.3 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (61%)
  • 4 star
    (21%)
  • 3 star
    (12%)
  • 2 star
    (3%)
  • 1 star
    (3%)
5 out of 5 stars

My Atomic Silver Ride!

markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
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Used 2022 Lexus RX 450h in Des Moines, IA Values

Estimated values
2022 Lexus RX 450h F SPORT Handling 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$38,626$39,847$41,119
Clean$38,112$39,295$40,527
Average$37,254$38,375$39,542
Rough$36,139$37,179$38,261

The average list price of a used 2022 Lexus RX 450h in Des Moines, Iowa is $45,735. The average mileage on a used Lexus RX 450h 2022 for sale in Des Moines, Iowa is 40,420. Based on the average mileage of 40,420 for used 2022 Lexus RX 450h for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Des Moines, Iowa to be $37,254.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.