Skip to FiltersReport abuse
208 listings
- Price Drop$46,597fair price$207 below market
- 15,613 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Fort Wayne (436 mi away)
Close
Located in Fort Wayne, IN / 436 miles away from Des Moines, IA
Driver Seat & Steering Wheel Memory, Heated & Ventilated Front Seats, Moonroof & Aluminum Roof Rails, Premium Package, Radio: AM/FM/HD w/9-Speaker Pre...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA4NC078699
Stock: FL1499P
Certified Pre-Owned: Yes
Listed since: 03-28-2025 - $44,833good price$1,314 below market
- 37,426 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Lupient Chevrolet (225 mi away)
Close
Located in Minneapolis, MN / 225 miles away from Des Moines, IA
Sale prices include convenient and competitive financing through our lenders.ONE OWNER, NO ACCIDENTS, 3.5L V6 DOHC VVT-i 24V, AWD, Black w/NuLuxe Seat...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA0NC073239
Stock: LHP8454
Certified Pre-Owned: No
Listed since: 02-14-2025 - $34,697fair price$772 above market
- 51,579 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Napleton's Arlington Heights Chrysler Jeep Dodge Ram (290 mi away)
Close
Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
2018 Lexus RX 450h Caviar AWD** Navigation Package, Power Tilt & Slide Sun/Moon Roof, Premium Package, Tow Prep Package **Automatic Temperature Contro...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCAXJC027662
Stock: PM7241
Certified Pre-Owned: No
Listed since: 04-21-2025 - $47,972fair price$272 below market
- 20,752 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Old Orchard Nissan (302 mi away)
Close
Located in Skokie, IL / 302 miles away from Des Moines, IA
Recent Arrival!Odometer is 13947 miles below market average! 31/28 City/Highway MPG 31/28 City/Highway MPG450h2022 Lexus RX 450hAtomic Silver 3.5L V...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA3NC085756
Stock: T1344
Certified Pre-Owned: No
Listed since: 02-12-2025 - New Listing$50,990fair price$1,784 below market
- 28,511 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Philadelphia, PA / 971 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA9NC077243
Stock: 2003709137
Certified Pre-Owned: No
Listed since: 05-02-2025 - New Listing$38,998fair price$610 below market
- 32,810 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax Madison (232 mi away)
Close
Located in Madison, WI / 232 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA1JC023001
Stock: 26509847
Certified Pre-Owned: No - 29,876 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from TX to IA*
Close
Located in Corpus Christi, TX / 984 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA0NC077999
Stock: 26403175
Certified Pre-Owned: No- Price Drop$46,111fair price$46 below market
- 38,501 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Stew Hansen's Dodge Chrysler Jeep Ram City (10 mi away)
Close
Located in Urbandale, IA / 10 miles away from Des Moines, IA
Stew Hansen Dodge Ram Chrysler Jeep RAM Fiat is pumped up to offer this attractive-looking 2022 Lexus RX. 450h AWD31/28 City/Highway MPGCall now to ge...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA9NC092467
Stock: G25H0301
Certified Pre-Owned: No
Listed since: 04-02-2025 - Price Drop$50,998fair price$1,474 above market
- 14,297 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from CO to IA*
Close
Located in Federal Heights, CO / 609 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2NC093637
Stock: 26550007
Certified Pre-Owned: No - New Listing$51,998fair price$1,356 above market
- 14,596 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from CO to IA*
Close
Located in Littleton, CO / 613 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2NC089068
Stock: 27129981
Certified Pre-Owned: No - New Listing$37,998good price
- 57,304 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from TX to IA*
Close
Located in Houston, TX / 808 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2LC044726
Stock: 27480412
Certified Pre-Owned: No - Price Drop$39,495fair price$35 below market
- 61,129 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- INFINITI of Naperville (279 mi away)
Close
Located in Naperville, IL / 279 miles away from Des Moines, IA
New Price! *** INFINITI CERTIFIED ***, ***APPLE CARPLAY and ANDROID AUTO***, ***BLUETOOTH/HANDSFREE CONNECTION***, ***ALL WHEEL DRIVE / 4X4***, * NEW ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA7NC081080
Stock: JA0722
Certified Pre-Owned: No
Listed since: 02-05-2025 - New Listing$39,906fair price$116 below market
- 58,066 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Watertown Chrysler Dodge Jeep Ram (287 mi away)
Close
Located in Watertown, SD / 287 miles away from Des Moines, IA
3.5L V6 DOHC VVT-i 24V, AWD, Parchment w/Semi-Aniline Leather Seat Trim.2022 Lexus RX 450h Eminent White Pearl AWD eCVT 3.5L V6 DOHC VVT-i 24V 31...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA9NC080692
Stock: Z5029A
Certified Pre-Owned: No
Listed since: 10-20-2024 - New Listing
- 25,410 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from CO to IA*
Close
Located in Colorado Springs, CO / 615 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA8NC093710
Stock: 27084898
Certified Pre-Owned: No - Price Drop$31,577fair price$1,544 above market
- 87,297 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 31 City / 28 Hwy MPG
- Mercedes-Benz of St Charles (272 mi away)
Close
Located in Saint Charles, IL / 272 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA4JC024014
Stock: Q1108
Certified Pre-Owned: No
Listed since: 04-13-2025 - New Listing$47,395fair price$159 above market
- 28,831 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Jackie Cooper INFINITI (404 mi away)
Close
Located in Tulsa, OK / 404 miles away from Des Moines, IA
The 2022 Lexus RX 450h is a luxury midsize hybrid SUV that offers a smooth, fuel-efficient ride with upscale comfort. It features a 3.5L V6 hybrid pow...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA1NC090468
Stock: MS90468A
Certified Pre-Owned: No
Listed since: 03-22-2025 - Price Drop$41,687good price$1,980 below market
- 60,090 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Fort Wayne (436 mi away)
Close
Located in Fort Wayne, IN / 436 miles away from Des Moines, IA
2022 Lexus RX 450h Black AWDAt Bob Rohrman Dealerships Our selection is Outstanding. We believe that we truly have a certified preowned vehicle for ev...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2NC080418
Stock: FL1520P
Certified Pre-Owned: No
Listed since: 04-10-2025 - New Listing$49,990fair price$1,422 above market
- 29,655 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Birmingham, AL / 671 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA9NC081163
Stock: 2003713293
Certified Pre-Owned: No
Listed since: 05-07-2025 - Price Drop$45,101fair price$752 above market
- 50,687 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- McLaughlin Cadillac (162 mi away)
Close
Located in Moline, IL / 162 miles away from Des Moines, IA
2022 Lexus RX 450h Black AWD eCVT 3.5L V6 DOHC VVT-i 24V3.5L V6 DOHC VVT-i 24V, AWD, Birch Artificial Leather, 4-Wheel Disc Brakes, ABS brakes, Alloy ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA0NC078151
Stock: C2582A
Certified Pre-Owned: No
Listed since: 03-10-2025 - $45,998fair price$162 above market
- 40,362 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from PA to IA*
Close
Located in Mechanicsburg, PA / 869 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA9NC092307
Stock: 27459841
Certified Pre-Owned: No - $45,901fair price$1,115 above market
- 47,999 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Nelson Mazda Tulsa (405 mi away)
Close
Located in Tulsa, OK / 405 miles away from Des Moines, IA
Recent Arrival!Blue 2022 Lexus RX 450h 4D Sport Utility AWD 3.5L V6 DOHC VVT-i 24V eCVT 31/28 City/Highway MPG CARFAX One-Owner.NON-Commissioned Sales...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA1NC088932
Stock: P18048
Certified Pre-Owned: No
Listed since: 04-26-2025
Showing 43 - 63 out of 208 listings
Consumer Reviews for the Lexus RX 450h
Read recent reviews for the Lexus RX 450h
My Atomic Silver Ride!
markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
Used 2022 Lexus RX 450h in Des Moines, IA Values
Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $34,078 | $35,101 | $36,165 |
| Clean | $33,624 | $34,615 | $35,645 |
| Average | $32,868 | $33,804 | $34,779 |
| Rough | $31,884 | $32,751 | $33,652 |
The average list price of a used 2022 Lexus RX 450h in Des Moines, Iowa is $44,678. The average mileage on a used Lexus RX 450h 2022 for sale in Des Moines, Iowa is 39,561. Based on the average mileage of 39,561 for used 2022 Lexus RX 450h for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Des Moines, Iowa to be $32,868.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.