Skip to FiltersReport abuse
3,047 listings
- $37,331fair price$284 above market
- 44,325 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Towson (441 mi away)
Close
Located in Towson, MD / 441 miles away from Columbia, SC
CARFAX One-Owner. 2021 Lexus RX 350 Nebula Gray Pearl AWD 8-Speed Automatic 3.5L V6 DOHC 24V---VERY WELL EQUIPPED---, ---FREE CARWASHES---, ---BEAUTIF...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1MC278965
Stock: BT1494
Certified Pre-Owned: No
Listed since: 02-14-2025 - $40,388fair price$407 above market
- 53,239 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Johnson Lexus of Durham (172 mi away)
Close
Located in Durham, NC / 172 miles away from Columbia, SC
L/CERTIFIED SALES EVENT! PRICED WAY BELOW JD POWER CERTIFIED RETAIL VALUE OF $42,675 FOR A QUICK AND HASSLE-FREE SALE! 5.75% FINANCING UP TO 72 MONTHS...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA7MC280140
Stock: DP10893
Certified Pre-Owned: Yes
Listed since: 06-05-2025 - New Listing$40,473fair price$1,079 above market
- 41,364 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- AutoNation Hyundai Savannah (144 mi away)
Close
Located in Savannah, GA / 144 miles away from Columbia, SC
12.3" Navigation SystemIntuitive Parking Assist W/Panoramic View MonitorTilt & Slide MoonroofWheels: 20" Split 5-Spoke Machined AlloyHeated & Vent...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA3MC214902
Stock: MC214902
Certified Pre-Owned: No
Listed since: 06-20-2025 - $32,498fair price$885 above market
- 80,886 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Lexus of Clearwater (432 mi away)
Close
Located in Clearwater, FL / 432 miles away from Columbia, SC
The following items have been reconditioned on this vehicle: all new tires! 12.3" Navigation SystemIntuitive Parking Assist W/Panoramic View Monit...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA2MC217550
Stock: MC217550
Certified Pre-Owned: No
Listed since: 06-13-2025 - $39,985fair price$504 above market
- 51,610 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Germain Lexus of Dublin (430 mi away)
Close
Located in Dublin, OH / 430 miles away from Columbia, SC
L/CERTIFIED 2021 LEXUS RX 350 WITH A PERFECT 1-OWNER CARFAX!!! *PREMIUM PACKAGE *COLD WEATHER PACKAGE *LEXUS SAFETY SYSTEM+ 2.0 *A...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6MC270473
Stock: 54797A
Certified Pre-Owned: Yes
Listed since: 06-09-2025 - $36,257fair price$12 above market
- 46,658 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Lexus of Tampa Bay (430 mi away)
Close
Located in Tampa, FL / 430 miles away from Columbia, SC
The following items have been reconditioned on this vehicle: new battery! Tilt & Slide MoonroofWheels: 20" Split 5-Spoke Machined AlloyHeated & V...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA1MC192432
Stock: MC192432
Certified Pre-Owned: Yes
Listed since: 06-18-2025 - Price Drop$34,750fair price$991 below market
- 51,405 miles
- 1 accident, 3 owners, rental vehicle
- 5 Seats, 20 City / 27 Hwy MPG
- Ourisman Chevrolet of Rockville (406 mi away)
Close
Located in Rockville, MD / 406 miles away from Columbia, SC
This 2021 Caviar Lexus RX 350 FWD is well equipped and includes these features and benefits:.Parchment w/Semi-Aniline Leather Seat Trim. 3.5L V6 DOHC ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA7MC213946
Stock: N5287
Certified Pre-Owned: No
Listed since: 06-05-2025 - $38,465fair price$996 below market
- 37,748 miles
- 1 accident, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Walker Chevrolet (303 mi away)
Close
Located in Nitro, WV / 303 miles away from Columbia, SC
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA8MC291279
Stock: GMR643A
Certified Pre-Owned: No
Listed since: 02-06-2025 - New Listing
- 14,748 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Asheville (133 mi away)
Close
Located in Asheville, NC / 133 miles away from Columbia, SC
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8MC299425
Stock: 27082450
Certified Pre-Owned: No - Price Drop$30,609fair price$582 above market
- 102,787 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Honda of Mansfield (468 mi away)
Close
Located in Ontario, OH / 468 miles away from Columbia, SC
2021 Lexus RX 350 F Sport Silver 3.5L V6 DOHC 24V 8-Speed Automatic AWD ***CAR FAX 1 OWNER***, Accident free CARFAX, 9 Speakers, Apple CarPlay/Android...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA6MC299610
Stock: L256346PA
Certified Pre-Owned: No
Listed since: 05-24-2025 - Price Drop$42,458fair price$280 above market
- 39,435 miles
- 2 accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Johnson Lexus of Raleigh (185 mi away)
Close
Located in Raleigh, NC / 185 miles away from Columbia, SC
Experience luxury and advanced technology in this Certified 2021 Lexus RX 350, with only 39,337 miles. This meticulously maintained midsize SUV offers...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA4MC198712
Stock: R35616A
Certified Pre-Owned: Yes
Listed since: 05-31-2025 - 14,925 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Lynchburg (247 mi away)
Close
Located in Lynchburg, VA / 247 miles away from Columbia, SC
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5MC267368
Stock: 27239510
Certified Pre-Owned: No- New Listing$35,998fair price$211 above market
- 37,153 miles
- 5 Seats, 20 City / 27 Hwy MPG
- CarMax Roswell (188 mi away)
Close
Located in Roswell, GA / 188 miles away from Columbia, SC
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAA3MC213735
Stock: 27386417
Certified Pre-Owned: No - 55,714 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Stone Mountain Nissan (175 mi away)
Close
Located in Lilburn, GA / 175 miles away from Columbia, SC
Safety Inspected, Fully detailed, Leather, Backup Camera, Bluetooth, AWD, Circuit Red w/F SPORT NuLuxe Seat Trim, 3.329 Axle Ratio, 4-Wheel Disc Brake...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA6MC287005
Stock: PN10869A
Certified Pre-Owned: No
Listed since: 04-29-2025- Price Drop$40,700fair price$1,021 above market
- 32,822 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lindsay Manassas Chrysler Dodge Jeep Ram (380 mi away)
Close
Located in Manassas, VA / 380 miles away from Columbia, SC
*LOW MILEAGE*, POWER SUNROOF / SUNROOF / POWER TILT SLIDING ROOF, GPS/ NAVIGATION, APPLE CARPLAY/ANDROID AUTO, BLUETOOTH, STEERING WHEEL AUDIO CONTROL...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA1MC262023
Stock: MR1304
Certified Pre-Owned: No
Listed since: 05-06-2025 - $37,301fair price$1,140 above market
- 72,898 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Germain Lexus of Easton (424 mi away)
Close
Located in Columbus, OH / 424 miles away from Columbia, SC
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1MC260692
Stock: 50935A
Certified Pre-Owned: Yes
Listed since: 06-09-2025 - 25,902 miles
- No accidents, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Lexus of Tampa Bay (430 mi away)
Close
Located in Tampa, FL / 430 miles away from Columbia, SC
The following items have been reconditioned on this vehicle: new pair of tires! Accessory PackageTouch-Free Power Rear Door W/Kick SensorLane Kee...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAA0MC195579
Stock: MC195579
Certified Pre-Owned: Yes
Listed since: 06-04-2025- 33,568 miles
- No accidents, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Audi Indianapolis (490 mi away)
Close
Located in Indianapolis, IN / 490 miles away from Columbia, SC
Fully Inspected and Serviced. Odometer is 17809 miles below market average! Awards: * JD Power Initial Quality Study (IQS) * ALG Residual Value Awards...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAA6MC210912
Stock: AIT210912
Certified Pre-Owned: No
Listed since: 06-17-2025- 47,357 miles
- No accidents, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Carvana - Charlotte (79 mi away)
- Home delivery*
Close
Located in Charlotte, NC / 79 miles away from Columbia, SC
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAA3MC194068
Stock: 2003812711
Certified Pre-Owned: No
Listed since: 06-11-2025- Price Drop$39,990great price$7,572 below market
- 42,759 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Butler Lexus of South Atlanta (203 mi away)
Close
Located in Union City, GA / 203 miles away from Columbia, SC
**OEM CERTIFIED** Thank you for choosing BUTLER LEXUS OF SOUTH ATLANTA, this Matador Red Mica 2022 Lexus RX 350 is a great choice! Check out the follo...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA3NC243091
Stock: 2025365A
Certified Pre-Owned: Yes
Listed since: 04-30-2025 - 32,305 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Dayton (422 mi away)
Close
Located in West Carrollton, OH / 422 miles away from Columbia, SC
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA2MC277047
Stock: 27111515
Certified Pre-Owned: No
Showing 22 - 42 out of 3,047 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Always go back to a Lexus
Jim R., 10/28/2020
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A)
While I’ve only had the car a week now, first impressions have settled in. First, the RX is a noticeable improvement from my 2018 Volvo XC60. It’s quieter, smoother, and much more comfortable. The features I gained over the Volvo are all little things that appeal to me. For example, the electrically adjustable steering wheel as part of the memory seating position. The fact that the seat … adjusts to my driving position when starting and retracts when stopping are features the Volvo lacked. The Mark Levenson sound system is the best I’ve ever heard in any car. The sometimes maligned trackpad is extremely easy to use, just adding to the excellent user interface overall. I expected the RX to be quiet and it doesn’t disappoint. The ride is so smooth that I deliberately drove over a small section of a local road that is just a mess of badly done patchwork. The Volvo felt like a stagecoach over this small section, the RX is like a pillow top mattress over the same section. The 20” Michelin tires add to the comfort.
My RX included the luxury package, heads up display, heated and cooled seats, triple beam LED headlights, panoramic moonroof and leather upholstery. Overall it is well put together package with more than enough luxury features for what I wanted without the price of the German cars.
This is the fourth Lexus over many years, I always seem to come back the brand.
Used 2021 Lexus RX 350 in Columbia, SC Values
Estimated values
2021 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $31,848 | $34,287 | $36,729 |
| Clean | $31,350 | $33,742 | $36,137 |
| Average | $30,521 | $32,835 | $35,149 |
| Rough | $29,443 | $31,656 | $33,865 |
The average list price of a used 2021 Lexus RX 350 in Columbia, South Carolina is $38,816. The average mileage on a used Lexus RX 350 2021 for sale in Columbia, South Carolina is 45,696. Based on the average mileage of 45,696 for used 2021 Lexus RX 350 for sale in Columbia, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2021 in Columbia, South Carolina to be $30,521.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.