Skip to FiltersReport abuse
3,047 listings
- $44,988good price$1,812 below market
- 27,587 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Johnson Lexus of Durham (172 mi away)
Close
Located in Durham, NC / 172 miles away from Columbia, SC
L-CERTIFIED SALES EVENT! 5.75% FINANCING FOR UP TO 72 MONTHS! LEXUS CERTIFIED UNLIMITED MILEAGE WARRANTY WITH $0 DEDUCTIBLE UNTIL 11/12/2028! YOU ALSO...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA0NC252458
Stock: DP10805
Certified Pre-Owned: Yes
Listed since: 05-21-2025 - New Listing$38,989good price$2,368 below market
- 50,495 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Jim Ellis Chevrolet of Atlanta (187 mi away)
Close
Located in Atlanta, GA / 187 miles away from Columbia, SC
CARFAX One-Owner. Clean CARFAX. Atomic Silver 2022 Lexus RX 350 w/ Premium Package FWD 8-Speed Automatic 3.5L V6 DOHC 24V Glazed Caramel w/Semi-Anilin...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAAXNC246070
Stock: T15251A
Certified Pre-Owned: No
Listed since: 06-21-2025 - $43,500fair price$620 below market
- 17,474 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Mercedes-Benz of Catonsville (429 mi away)
Close
Located in Baltimore, MD / 429 miles away from Columbia, SC
Recent Arrival! CARFAX One-Owner. 2022 Lexus RX 350, 4D Sport Utility, 3.5L V6 DOHC 24V, AWD, Caviar, Parchment w/NuLuxe Seat Trim, Accessory Package,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC351972
Stock: 000P7502
Certified Pre-Owned: No
Listed since: 05-21-2025 - $46,662fair price$397 below market
- 28,793 miles
- No accidents, 2 owners, corporate fleet vehicle
- 5 Seats, 20 City / 27 Hwy MPG
- Jim Hudson Lexus (5 mi away)
Close
Located in Columbia, SC / 5 miles away from Columbia, SC
L/Certified Details: * CERTIFIED WARRANTY: Unlimited-mileage warranty up to 6 years. Balance of new car warranty (4 Year/50K Miles) plus 2 Year/Unlimi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA4NC249885
Stock: CP9783
Certified Pre-Owned: Yes
Listed since: 04-05-2025 - Price Drop$42,792good price$1,629 below market
- 19,167 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Clearwater (432 mi away)
Close
Located in Clearwater, FL / 432 miles away from Columbia, SC
Tilt & Slide MoonroofHeated & Ventilated Front SeatsIntuitive Parking Assist & Rr Cross Traffic AlertSun/MoonroofPremium Paint (Pj)Premium Packag...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC365790
Stock: NC365790
Certified Pre-Owned: No
Listed since: 06-16-2025 - $40,000good price$2,328 below market
- 44,288 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Koons Tysons Chevy GMC (394 mi away)
Close
Located in Vienna, VA / 394 miles away from Columbia, SC
POWER MOONROOF / SUNROOF / SINGLE PANE ROOF, NAVIGATION / GPS / NAV, BLIND SPOT MONITORING / BLIND SPOT ALERT, DYNAMIC RADAR CRUISE CONTROL / ADAPTIVE...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA6NC335717
Stock: K6953
Certified Pre-Owned: No
Listed since: 05-24-2025 - $45,500good price$1,478 below market
- 18,467 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Passport INFINITI of Alexandria (391 mi away)
Close
Located in Alexandria, VA / 391 miles away from Columbia, SC
***F SPORT***Recent Arrival! 2022 Lexus RX 350 F Sport Grey AWD 3.5L V6 DOHC 24V*AWD, Black Artificial Leather*Clean CARFAX!!Introducing our PASSPOR...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA1NC353901
Stock: 118215A
Certified Pre-Owned: No
Listed since: 05-10-2025 - Price Drop$48,662fair price$87 below market
- 28,033 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Jim Hudson Lexus (5 mi away)
Close
Located in Columbia, SC / 5 miles away from Columbia, SC
L/Certified Details: * 161 Point Inspection * Roadside Assistance * Vehicle History * Limited Warranty: 24 Month/Unlimited Mile * Warranty Deductible:...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA2NC240800
Stock: CP9839
Certified Pre-Owned: Yes
Listed since: 06-03-2025 - $43,493fair price$1,345 below market
- 21,627 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Byers Mazda (430 mi away)
Close
Located in Columbus, OH / 430 miles away from Columbia, SC
2022 Gray Lexus RX 350 3.5L V6 DOHC 24V This Lexus RX has many features and is well equipped including, Collision Avoidance System, Collision Warning ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC359980
Stock: M255700A
Certified Pre-Owned: No
Listed since: 05-08-2025 - $42,500fair price$1,300 below market
- 22,784 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Koons Westminster Toyota (440 mi away)
Close
Located in Westminster, MD / 440 miles away from Columbia, SC
**** Balance of Factory Warranty ****, Bluetooth, Hands-Free, Leather, Sunroof, Keyless Entry, Keyless Start, Satellite Radio, AWD, Parchment Artifici...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC360898
Stock: KTWP220514
Certified Pre-Owned: No
Listed since: 05-08-2025 - $42,888good price$2,053 below market
- 40,034 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Johnson Lexus of Durham (172 mi away)
Close
Located in Durham, NC / 172 miles away from Columbia, SC
L-CERTIFIED SALES EVENT! 5.75% FINANCING FOR UP TO 72 MONTHS! LEXUS CERTIFIED UNLIMITED MILEAGE WARRANTY WITH $0 DEDUCTIBLE UNTIL AUG/2028! YOU ALSO G...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA7NC257737
Stock: D42407A
Certified Pre-Owned: Yes
Listed since: 05-24-2025 - $43,804good price$1,566 below market
- 35,673 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Honda of Indian Trail (70 mi away)
Close
Located in Indian Trail, NC / 70 miles away from Columbia, SC
2022 Lexus RX 350 Atomic Silver FWDBirch w/Semi-Aniline Leather Seat Trim. 20/27 City/Highway MPGClean CARFAX. CARFAX One-Owner.So visit www.h...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2AZMAA5NC228206
Stock: ANC228206
Certified Pre-Owned: No
Listed since: 05-23-2025 - $42,988good price$1,873 below market
- 36,248 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Johnson Lexus of Durham (172 mi away)
Close
Located in Durham, NC / 172 miles away from Columbia, SC
L-CERTIFIED SALES EVENT! 5.75% FINANCING FOR UP TO 72 MONTHS! LEXUS CERTIFIED UNLIMITED MILEAGE WARRANTY WITH $0 DEDUCTIBLE UNTIL 05/27/2028! YOU ALSO...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA9NC246223
Stock: DP10852
Certified Pre-Owned: Yes
Listed since: 05-30-2025 - $37,000good price$1,466 below market
- 59,601 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Hall Toyota Elizabeth City (310 mi away)
Close
Located in Elizabeth City, NC / 310 miles away from Columbia, SC
We are currently offering Vehicle Purchase Home Delivery by appointment. Please contact for details., AWD, Black w/NuLuxe Seat Trim. Nebula Gray Pearl...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXNC347489
Stock: 2251746A
Certified Pre-Owned: No
Listed since: 04-15-2025 - New Listing$43,920good price$2,292 below market
- 23,793 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- ALM Marietta (199 mi away)
Close
Located in Marietta, GA / 199 miles away from Columbia, SC
F SPORT APPEARANCE PKG..HEATED SEATS..COOLED SEATS..MEMORY SEATS..NAVIGATION..CROSS-TRAFFIC ALERT..BLIND SPOT MONITOR..LANE DEPARTURE WARNING..LANE KE...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA8NC362370
Stock: NC362370
Certified Pre-Owned: No
Listed since: 06-20-2025 - New Listing$46,590good price$2,313 below market
- 7,339 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Carvana - Indianapolis (484 mi away)
- Home delivery*
Close
Located in Indianapolis, IN / 484 miles away from Columbia, SC
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA6NC366380
Stock: 2003843015
Certified Pre-Owned: No
Listed since: 06-26-2025 - $35,998good price$2,262 below market
- 50,110 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Indianapolis (490 mi away)
Close
Located in Indianapolis, IN / 490 miles away from Columbia, SC
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1LC223785
Stock: 27351035
Certified Pre-Owned: No - $45,998fair price$1,332 below market
- 33,013 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax Winston-Salem (142 mi away)
Close
Located in Winston Salem, NC / 142 miles away from Columbia, SC
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA4NC368449
Stock: 27321196
Certified Pre-Owned: No - $31,999good price$1,354 below market
- 69,881 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 20 City / 27 Hwy MPG
- Automaxx of the Carolinas (89 mi away)
Close
Located in Summerville, SC / 89 miles away from Columbia, SC
Certified.Certification Program Details: 3 month/3000 Miles Certified Warranty2020 Lexus RX 350 FWDCurrent Odometer 69881, *Certified Pre-Owned 3 ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA8LC154517
Stock: B015
Certified Pre-Owned: No
Listed since: 06-17-2025 - New Listing$39,000good price$1,588 below market
- 62,243 miles
- No accidents, 2 owners, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- TLC Motors (78 mi away)
Close
Located in Moore, SC / 78 miles away from Columbia, SC
Clean CARFAX. 20/27 City/Highway MPGWhy pay more?? Experience Stress-Free Buying with No Haggle Pricing and buy with confidence from TLC Motors, you...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA6NC249712
Stock: SB9712
Certified Pre-Owned: No
Listed since: 06-21-2025 - New Listing$43,750fair price$201 below market
- 19,777 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Driver's Way (334 mi away)
Close
Located in Pelham, AL / 334 miles away from Columbia, SC
AWD, 19K LOW LOW MILES!, Alloy wheels, Apple CarPlay/Android Auto, Auto High-beam Headlights, Automatic temperature control, Collision Mitigation, Ext...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5NC351773
Stock: D63612
Certified Pre-Owned: No
Listed since: 12-13-2024
Showing 106 - 126 out of 3,047 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Always go back to a Lexus
Jim R., 10/28/2020
2021 Lexus RX 350 4dr SUV (3.5L 6cyl 8A)
While I’ve only had the car a week now, first impressions have settled in. First, the RX is a noticeable improvement from my 2018 Volvo XC60. It’s quieter, smoother, and much more comfortable. The features I gained over the Volvo are all little things that appeal to me. For example, the electrically adjustable steering wheel as part of the memory seating position. The fact that the seat … adjusts to my driving position when starting and retracts when stopping are features the Volvo lacked. The Mark Levenson sound system is the best I’ve ever heard in any car. The sometimes maligned trackpad is extremely easy to use, just adding to the excellent user interface overall. I expected the RX to be quiet and it doesn’t disappoint. The ride is so smooth that I deliberately drove over a small section of a local road that is just a mess of badly done patchwork. The Volvo felt like a stagecoach over this small section, the RX is like a pillow top mattress over the same section. The 20” Michelin tires add to the comfort.
My RX included the luxury package, heads up display, heated and cooled seats, triple beam LED headlights, panoramic moonroof and leather upholstery. Overall it is well put together package with more than enough luxury features for what I wanted without the price of the German cars.
This is the fourth Lexus over many years, I always seem to come back the brand.
Used 2022 Lexus RX 350 in Columbia, SC Values
Estimated values
2022 Lexus RX 350 4dr SUV (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $35,031 | $36,971 | $38,993 |
| Clean | $34,565 | $36,459 | $38,432 |
| Average | $33,787 | $35,606 | $37,498 |
| Rough | $32,775 | $34,496 | $36,283 |
The average list price of a used 2022 Lexus RX 350 in Columbia, South Carolina is $42,430. The average mileage on a used Lexus RX 350 2022 for sale in Columbia, South Carolina is 34,116. Based on the average mileage of 34,116 for used 2022 Lexus RX 350 for sale in Columbia, SC and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Columbia, South Carolina to be $33,787.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.