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1,523 listings
- New Listing$37,200good price$1,953 below market
- 70,112 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Milwaukee (310 mi away)
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Located in Milwaukee, WI / 310 miles away from Des Moines, IA
L/Certified Details: * Vehicle History * Limited Warranty: 24 Month/Unlimited Mile * Roadside Assistance * 161 Point Inspection * CERTIFIED...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5NC315751
Stock: L21189A
Certified Pre-Owned: Yes
Listed since: 09-19-2025 - $33,998fair price$709 below market
- 48,797 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- CarMax (In-stock online)
- Transfer available from NM to IA*
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Located in Albuquerque, NM / 828 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA6LC175446
Stock: 27479818
Certified Pre-Owned: No - New Listing$42,291good price$1,909 below market
- 39,133 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Ed Martin Toyota (414 mi away)
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Located in Noblesville, IN / 414 miles away from Des Moines, IA
RX 350 F Sport, 4D Sport Utility, 3.5L V6 DOHC 24V, 8-Speed Automatic, AWD, Ultra White, Circuit Red Artificial Leather.19/26 City/Highway MPGWireless...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA7NC315833
Stock: 621404A
Certified Pre-Owned: No
Listed since: 09-19-2025 - $42,990fair price$733 below market
- 22,033 miles
- 1 accident, 1 owner, corporate fleet vehicle
- 5 Seats, 20 City / 27 Hwy MPG
- Unlimited Motors Westfield (404 mi away)
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Located in Westfield, IN / 404 miles away from Des Moines, IA
Back Up Camera, Bluetooth, Sun/Moon Roof, Heated Seats, Touch Screen, Cooled Heats, Blind Spot, Heated Steering Wheel, RX 350, 4D Sport Utility, 3.5L ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA4NC233248
Stock: STK233248
Certified Pre-Owned: No
Listed since: 08-29-2025 - $49,995fair price$1,153 above market
- 31,696 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (288 mi away)
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Located in Schaumburg, IL / 288 miles away from Des Moines, IA
**ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, **Lexus Safety System Plus**, ** Lane Departure Warning, *...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA1NC367680
Stock: Q3689
Certified Pre-Owned: Yes
Listed since: 09-09-2025 - $43,887fair price$178 above market
- 36,836 miles
- No accidents, 1 owner, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Serra Chevrolet (487 mi away)
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Located in Bartlett, TN / 487 miles away from Des Moines, IA
AWD. CARFAX One-Owner.AWD, 20 x 8 Aluminum Wheels, 3.33 Axle Ratio, 4-Wheel Disc Brakes, 9 Speakers, ABS brakes, Air Conditioning, Alloy wheels, AM/FM...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA6NC337709
Stock: PNC337709
Certified Pre-Owned: No
Listed since: 07-30-2025 - $43,990fair price$128 above market
- 26,131 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Unlimited Motors Westfield (404 mi away)
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Located in Westfield, IN / 404 miles away from Des Moines, IA
Back Up Camera, Bluetooth, Sun/Moon Roof, Heated Seats, Touch Screen, Cooled Heats, Blind Spot, Heated Steering Wheel, RX 350 F Sport, 4D Sport Utilit...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA6NC331683
Stock: STK331683
Certified Pre-Owned: No
Listed since: 08-22-2025 - Price Drop$41,999fair price$1,074 above market
- 30,788 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Tom Kadlec Honda (178 mi away)
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Located in Rochester, MN / 178 miles away from Des Moines, IA
Lexus RX 350 3.5L V6 DOHC 24V Carfax 1 owner, AWD, Parchment Artificial Leather, Air Conditioning, AM/FM/CD Radio, Apple CarPlay/Android Auto, Automat...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA3NC344353
Stock: P12157
Certified Pre-Owned: No
Listed since: 09-11-2025 - Price Drop$45,499fair price$516 above market
- 28,365 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wayzata (234 mi away)
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Located in Wayzata, MN / 234 miles away from Des Moines, IA
Recent Arrival! CARFAX One-Owner. Certified. Caviar 2022 Lexus RX 4D Sport Utility 350 3.5L V6 DOHC 24V AWD 19/26 City/Highway MPG Odometer is 4365 mi...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA9NC320638
Stock: PRS507
Certified Pre-Owned: Yes
Listed since: 09-09-2025 - New Listing$23,900good price$965 below market
- 109,133 miles
- 1 accident, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Unlimited Motors Fishers (414 mi away)
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Located in Fishers, IN / 414 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2BZMCA2JC157378
Stock: STK157378
Certified Pre-Owned: No
Listed since: 09-09-2025 - $41,984fair price$920 above market
- 29,376 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Tom Wood Volkswagen Noblesville (414 mi away)
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Located in Noblesville, IN / 414 miles away from Des Moines, IA
*** SOPHISTICATED LUXURY & STRONG PERFORMANCE IN A MIDSIZE SUV! ***2022 Lexus RX 350 9 Speakers, Apple CarPlay/Android Auto, Compass, Emergency comm...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA9NC228594
Stock: VNI228594
Certified Pre-Owned: No
Listed since: 08-20-2025 - New Listing$43,500good price$2,173 below market
- 43,666 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Reliable Superstore (305 mi away)
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Located in Springfield, MO / 305 miles away from Des Moines, IA
Recent Arrival! Odometer is 2352 miles below market average! CARFAX One-Owner. Clean CARFAX. 2022 Lexus RX 350 F Sport Nightfall Mica 4D Sport Utility...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA2NC360940
Stock: NC360940P
Certified Pre-Owned: No
Listed since: 09-22-2025 - $25,799fair price$821 above market
- 99,831 miles
- No accidents, 3 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- KNB Motors (297 mi away)
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Located in Northlake, IL / 297 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2BZMCA5JC138453
Stock: 12230
Certified Pre-Owned: No - Price Drop$36,464fair price$675 above market
- 38,115 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Kayser Chrysler Center (230 mi away)
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Located in Sauk City, WI / 230 miles away from Des Moines, IA
* PREMIUM PACKAGE ** COLD WEATHER PACKAGE ** AWD ** POWER MOONROOF ** INTUITIVE PARKING ASSIST W/ BRAKING ** LANE DEPARTURE WARNING W/ STEERING ASSIST...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5LC238810
Stock: UAS11310
Certified Pre-Owned: No
Listed since: 08-15-2025 - $49,988fair price$1,041 below market
- 12,432 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (308 mi away)
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Located in Chicago, IL / 308 miles away from Des Moines, IA
Recent Arrival! Caviar 2022 Lexus RX 350 F Sport **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES, **APPL...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA4NC368330
Stock: S1777A
Certified Pre-Owned: Yes
Listed since: 09-08-2025 - $36,590fair price
- 31,989 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
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Located in Dallas, TX / 631 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0LC242859
Stock: 2003789071
Certified Pre-Owned: No
Listed since: 06-11-2025 - New Listing$32,998good price$1,156 below market
- 52,779 miles
- 5 Seats, 19 City / 26 Hwy MPG
- CarMax (In-stock online)
- Transfer available from MD to IA*
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Located in Laurel, MD / 899 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1LC249013
Stock: 27919890
Certified Pre-Owned: No - 30,165 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Jack Schmitt Chevrolet of O'Fallon (285 mi away)
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Located in O Fallon, IL / 285 miles away from Des Moines, IA
Clean CARFAX. Odometer is 5448 miles below market average! This 2022 Lexus RX comes equipped with the following - AWD, 18' x 8' Aluminum Wheels, 3.33 ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC351611
Stock: 16386P
Certified Pre-Owned: No
Listed since: 08-07-2025- Price Drop$42,999fair price$654 above market
- 41,919 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Wayzata (234 mi away)
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Located in Wayzata, MN / 234 miles away from Des Moines, IA
Lexus Certified Pre-Owned — Exceptional Quality, Unmatched Peace of MindEvery Lexus Certified Pre-Owned vehicle undergoes a comprehensive 161-point i...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA0NC347436
Stock: PRS505
Certified Pre-Owned: Yes
Listed since: 08-29-2025 - $29,495fair price$123 below market
- 67,815 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Schepel Cadillac (324 mi away)
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Located in Merrillville, IN / 324 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2BZMCA3JC139701
Stock: SC514A
Certified Pre-Owned: No
Listed since: 05-31-2025 - New Listing$32,998fair price$698 below market
- 50,823 miles
- 5 Seats, 20 City / 27 Hwy MPG
- CarMax (In-stock online)
- Transfer available from SC to IA*
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Located in Charleston, SC / 962 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA0LC152289
Stock: 27607462
Certified Pre-Owned: No
Showing 106 - 126 out of 1,523 listings
Consumer Reviews for the Lexus RX 350
Read recent reviews for the Lexus RX 350
Avid RX owner
Wendy, 12/08/2019
2020 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 8A)
I drive extensively and this is my fifth RX. Yes number 5, when you drive to remote areas it all about realizability. Previously I had the 2015 RX which drove fine but had slot of temperamental electronics. The new 2020 has premium package offers every safety feature, brake hold, cross traffic front and rear, blind spot warning you name it. I do love the heated steering wheel, and the … auto heated seats. The app works great for remote start and locking. My only comment is I think the car sounds a bit tinny when you run it through the car was and at times when closing the doors, I hope the body is still as rugged as my previous models. Highly recommend.
Used 2022 Lexus RX 350 in Des Moines, IA Values
Estimated values
2022 Lexus RX 350 F SPORT 4dr SUV AWD (3.5L 6cyl 8A) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $34,815 | $37,088 | $39,458 |
| Clean | $34,351 | $36,574 | $38,891 |
| Average | $33,578 | $35,718 | $37,945 |
| Rough | $32,573 | $34,605 | $36,716 |
The average list price of a used 2022 Lexus RX 350 in Des Moines, Iowa is $39,191. The average mileage on a used Lexus RX 350 2022 for sale in Des Moines, Iowa is 44,854. Based on the average mileage of 44,854 for used 2022 Lexus RX 350 for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 350 2022 in Des Moines, Iowa to be $33,578.
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