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77 listings
    • 38,355 miles
    • No accidents, 3 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of North Miami (12 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in North Miami, FL / 12 miles away from Miami, FL

    RX 450h F Sport Mark Levinson, AWD, Nebula Gray Pearl, Circuit Red w/F SPORT NuLuxe Seat Trim, 12.3" Navigation System w/Mark Levinson Audio, Adaptive...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA6NC086383
    Stock: 25361902
    Certified Pre-Owned: Yes
    Listed since: 07-16-2025

  • $46,250
    good price
    $2,888 below market
    • 20,055 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Rick Case Kia (24 mi away)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sunrise, FL / 24 miles away from Miami, FL

    Priced below KBB Fair Purchase Price! CARFAX One-Owner. Clean CARFAX. 10 year or 100,000 mile Powertrain Warranty, 150 Point Inspection, Unlimited Car...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA0NC093300
    Stock: TNC093300
    Certified Pre-Owned: No
    Listed since: 08-24-2025

  • Price Drop
    $39,999
    good price
    $3,406 below market
    • 45,685 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Holman INEOS Grenadier (26 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fort Lauderdale, FL / 26 miles away from Miami, FL

    Holman INEOS Grenadier is pleased to offer this great 2022 Lexus RX Eminent White Pearl 450h with the following features:Apple CarPlay/Android Auto, A...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA1NC092639
    Stock: NC092639
    Certified Pre-Owned: No
    Listed since: 07-25-2025

  • Price Drop
    $45,295
    fair price
    $173 above market
    • 26,893 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Fort Myers (110 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fort Myers, FL / 110 miles away from Miami, FL

    CARFAX 1-Owner, L/ Certified. Heated Seats, Sunroof, All Wheel Drive, Satellite Radio, Hybrid, Back-Up Camera, Power Liftgate, HEATED LEATHER STEERING...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA7NC083539
    Stock: NC083539
    Certified Pre-Owned: Yes
    Listed since: 08-08-2025

  • New Listing
    Photos not available
    $43,136
    good price
    $2,654 below market
    • 43,750 miles
    • 5 Seats, 31 City / 28 Hwy MPG
    • Starling GMC (196 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Titusville, FL / 196 miles away from Miami, FL

    2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V 3.5L V6 DOHC VVT-i 24V, AWD.Recent Arrival! 31/28 City/Highway MPG

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA2NC089846
    Stock: 089846T
    Certified Pre-Owned: No
    Listed since: 09-23-2025

  • Price Drop
    • 42,236 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • BMW of South Miami (13 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Miami, FL / 13 miles away from Miami, FL

    2020 Lexus RX 450h For sale in. Eminent White Pearl Standout Features are, Blind Spot Monitor and Rear cross traffic Alert with braking, Pre-Collision...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA9LC048904
    Stock: 9Z05018A
    Certified Pre-Owned: No
    Listed since: 09-01-2025

  • $40,998
    great price
    $4,035 below market
    • 49,920 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from AZ to FL*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Gilbert, AZ / 1,952 miles away from Miami, FL

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA1MC064694
    Stock: 27621349
    Certified Pre-Owned: No

  • New Listing
    $39,990
    great price
    $2,221 below market
    • 53,059 miles
    • No accidents, 2 owners, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Sacramento, CA / 2,536 miles away from Miami, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2SGMDA1MC057409
    Stock: 2004094723
    Certified Pre-Owned: No
    Listed since: 09-20-2025

  • New Listing
    $43,998
    good price
    $3,107 below market
    • 34,764 miles
    • 1 accident, 3 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from NV to FL*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Henderson, NV / 2,164 miles away from Miami, FL

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA9MC060505
    Stock: 26477403
    Certified Pre-Owned: No

  • Price Drop
    $38,500
    fair price
    $1,215 below market
    • 51,143 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Mercedes-Benz of Palm Beach (64 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in West Palm Beach, FL / 64 miles away from Miami, FL

    CARFAX One-Owner. Clean CARFAX. Alloy wheels, AM/FM radio: SiriusXM, Apple CarPlay/Android Auto, Driver Seat and Steering Wheel Memory, Exterior Parki...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5MC058718
    Stock: MB61341A
    Certified Pre-Owned: No
    Listed since: 08-06-2025

  • Price Drop
    • 24,922 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from SC to FL*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Columbia, SC / 573 miles away from Miami, FL

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA1MC072048
    Stock: 27872896
    Certified Pre-Owned: No

  • Price Drop
    • 41,600 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Medford, OR / 2,652 miles away from Miami, FL

    CarFax No Accidents Reported,Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steeri...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA1MC057095
    Stock: MC057095H
    Certified Pre-Owned: No

  • New Listing
    $43,590
    great price
    $8,305 below market
    • 37,221 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Phoenix, AZ / 1,972 miles away from Miami, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA1NC089127
    Stock: 2003775711
    Certified Pre-Owned: No
    Listed since: 05-30-2025

  • $50,208
    great price
    $5,308 below market
    • 25,926 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • JM Lexus (34 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Margate, FL / 34 miles away from Miami, FL

    CARFAX One-Owner. Clean CARFAX.NO DEALER FEES!!!!!, LEXUS CERTIFIED, Mark Levinson Premium Audio Package, 3.5L V6 DOHC VVT-i 24V, AWD, Birch w/Semi-An...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA7NC090850
    Stock: P27601
    Certified Pre-Owned: Yes
    Listed since: 09-07-2025

  • New Listing
    $41,716
    good price
    $4,143 below market
    • 53,866 miles
    • No accidents, 2 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Lexington, KY / 876 miles away from Miami, FL

    Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Lane K...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA3NC088898
    Stock: NC088898A
    Certified Pre-Owned: No

  • Price Drop
    $27,991
    great price
    $3,796 below market
    • 60,625 miles
    • 1 accident, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Tamiami Hyundai (96 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Naples, FL / 96 miles away from Miami, FL

    CARFAX One-Owner.2018 Lexus RX Caviar 4D Sport Utility 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V NAVIGATION, BACK UP CAMERA, THIRD ROW SEATING, PUSH BUTTON...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2BGMCA7JC025657
    Stock: JC025657
    Certified Pre-Owned: No
    Listed since: 07-10-2025

  • Price Drop
    $40,990
    good price
    $3,273 below market
    • 38,147 miles
    • No accidents, 1 owner, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Columbus, OH / 992 miles away from Miami, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA9LC050928
    Stock: 2003964728
    Certified Pre-Owned: No
    Listed since: 08-28-2025

  • Price Drop
    $41,887
    good price
    $2,508 below market
    • 27,972 miles
    • No accidents, 3 owners, personal use
    • 5 Seats, 31 City / 28 Hwy MPG
    • Lexus of Sarasota (168 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sarasota, FL / 168 miles away from Miami, FL

    **LEXUS L/CERTIFIED VEHICLE * 6 YEARS UNLIMITED MILEAGE FACTORY WARRANTY** Clean CARFAX. LEATHER, REAR-VIEW CAMERA, BLIND SPOT WARNING, POWER MOONROOF...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4LC051985
    Stock: 2031420A
    Certified Pre-Owned: Yes
    Listed since: 09-07-2025

  • $48,000
    fair price
    $1,096 below market
    • 27,054 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • DeVoe Buick GMC of Naples (97 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Naples, FL / 97 miles away from Miami, FL

    Vehicle DetailsIntroducing the 2022 Lexus RX 450h F SPORT Handling, an exquisite blend of luxury and performance. With only 27,054 miles, this meticul...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2YGMDA8NC094839
    Stock: T26029A
    Certified Pre-Owned: No
    Listed since: 08-29-2025

  • Price Drop
    $43,998
    fair price
    $246 above market
    • 35,187 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Driveway (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Middletown, NY / 1,132 miles away from Miami, FL

    CarFax No Accidents Reported,CarFax 1-Owner,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated S...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA6NC087324
    Stock: NC087324T
    Certified Pre-Owned: No

    • 29,287 miles
    • No accidents, 1 owner, personal use only
    • 5 Seats, 31 City / 28 Hwy MPG
    • Carvana (In-stock online)
    • Home delivery*
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Dallas, TX / 1,102 miles away from Miami, FL

    At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA5NC081130
    Stock: 2003978237
    Certified Pre-Owned: No
    Listed since: 08-27-2025

Showing 1 - 21 out of 77 listings

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.4 out of 5 stars33 Reviews
Write a vehicle reviewSee all 33 reviews
  • 5 star
    (67%)
  • 4 star
    (18%)
  • 3 star
    (9%)
  • 2 star
    (0%)
  • 1 star
    (6%)
5 out of 5 stars

My Atomic Silver Ride!

markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
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Used 2022 Lexus RX 450h in Miami, FL Values

Estimated values
2022 Lexus RX 450h F SPORT Handling 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$37,323$38,502$39,730
Clean$36,826$37,969$39,159
Average$35,997$37,080$38,207
Rough$34,919$35,924$36,969

The average list price of a used 2022 Lexus RX 450h in Miami, Florida is $42,727. The average mileage on a used Lexus RX 450h 2022 for sale in Miami, Florida is 38,460. Based on the average mileage of 38,460 for used 2022 Lexus RX 450h for sale in Miami, FL and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Miami, Florida to be $35,997.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.