Skip to FiltersReport abuse
184 listings
- Price Drop$43,590great price$8,500 below market
- 37,221 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Las Vegas, NV / 1,214 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA1NC089127
Stock: 2003775711
Certified Pre-Owned: No
Listed since: 05-30-2025 - Price Drop$39,545great price$6,278 below market
- 62,077 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Fort Wayne (438 mi away)
Close
Located in Fort Wayne, IN / 438 miles away from Des Moines, IA
Experience true luxury at Lexus of Fort Wayne. From personalized service to world-class hospitality, your journey to exceptional driving begins here.T...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA6NC089963
Stock: FL1539P
Certified Pre-Owned: Yes
Listed since: 08-02-2025 - Price Drop$40,300great price$5,101 below market
- 68,600 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Spirit Lexus (264 mi away)
Close
Located in St. Louis, MO / 264 miles away from Des Moines, IA
Certified. Grecian Water 2022 Lexus RX 450h F Sport AWD eCVT 3.5L V6 DOHC VVT-i 24V ** LOCAL TRADE **, **ANDROID AUTO**, **APPLE CARPLAY**, **AWD**, *...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA0NC076013
Stock: P8N076013
Certified Pre-Owned: Yes
Listed since: 08-09-2025 - New Listing$41,716great price$4,276 below market
- 53,866 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
Close
Located in Lexington, KY / 550 miles away from Des Moines, IA
Rare Find,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Lane K...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA3NC088898
Stock: NC088898A
Certified Pre-Owned: No - New Listing$43,500great price$5,082 below market
- 46,800 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Serra Lexus Lansing (476 mi away)
Close
Located in Okemos, MI / 476 miles away from Des Moines, IA
CARFAX One-Owner. Clean CARFAX.RX 450h, 4D Sport Utility, 3.5L V6 DOHC VVT-i 24V, eCVT, AWD, Black w/NuLuxe Seat Trim, 12.3 Navigation System w/Mark L...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA5NC088692
Stock: L25635B
Certified Pre-Owned: No
Listed since: 09-08-2025 - $45,500good price$4,090 below market
- 52,835 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Lux Cars Chicago (294 mi away)
Close
Located in Buffalo Grove, IL / 294 miles away from Des Moines, IA
2022 LEXUS RX 450H AWD HYBRID SUV WITH 3.5L V6 HYBRID DRIVE SYSTEM AND CVT TRANSMISSION WITH PADDLE SHIFTERS. SOPHISTICATED NEBULA GRAY PEARL EXTERIOR...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA8NC094776
Stock: 9910
Certified Pre-Owned: No
Listed since: 08-13-2025 - New Listing$47,448good price$2,180 below market
- 22,127 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Golden Circle Ford Lincoln (485 mi away)
Close
Located in Jackson, TN / 485 miles away from Des Moines, IA
FREE 20 YEAR / 200,000 MILE POWERTRAIN WARRANTY, ONE OWNER, CLEAN CARFAX, AWD ALL WHEEL DRIVE, BLUETOOTH, SIRIUS XM SATELLITE RADIO, APPLE CARPLAY, GO...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA9NC074180
Stock: 1574238A
Certified Pre-Owned: No
Listed since: 09-17-2025 - $43,788good price$2,251 below market
- 45,449 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Frank Leta Acura (274 mi away)
Close
Located in Saint Louis, MO / 274 miles away from Des Moines, IA
Certified! 90 Day/3,000 Mile Limited Comprehensive Warranty and a 7 Year/100,000 Mile Limited Powertrain Warranty! One Owner/CARFAX No Accidents! Comp...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA5NC090120
Stock: PJK2104
Certified Pre-Owned: No
Listed since: 09-06-2025 - $43,998fair price$75 above market
- 35,187 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
Close
Located in Middletown, NY / 992 miles away from Des Moines, IA
CarFax No Accidents Reported,CarFax 1-Owner,Green Vehicle,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated S...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA6NC087324
Stock: NC087324T
Certified Pre-Owned: No - Price Drop$27,491good price$1,343 below market
- 89,811 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
Close
Located in Medford, OR / 1,491 miles away from Des Moines, IA
Rare Find,Green Vehicle,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Hands-Free Liftgate,Heated Seats,Heated Steering Wheel,Keyless Start,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA6JC027240
Stock: JC027240H
Certified Pre-Owned: No - $47,998fair price$3 below market
- 29,195 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from VA to IA*
Close
Located in Roanoke, VA / 784 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA5NC090215
Stock: 27842395
Certified Pre-Owned: No - $46,990fair price
- 29,287 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Dallas, TX / 631 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA5NC081130
Stock: 2003978237
Certified Pre-Owned: No
Listed since: 08-27-2025 - Price Drop$44,988fair price$1,102 below market
- 44,536 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Landers Toyota (480 mi away)
Close
Located in Little Rock, AR / 480 miles away from Des Moines, IA
Heated Seats, Moonroof, Nav System, iPod/MP3 Input, Satellite Radio, Hybrid, Power Liftgate, All Wheel Drive, PANORAMIC-VIEW MONITOR W/RR CROSS-TRA. P...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDAXNC081414
Stock: C081414L
Certified Pre-Owned: No
Listed since: 04-13-2025 - Price Drop$27,990fair price$246 below market
- 103,514 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Richmond, VA / 893 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA6JC024175
Stock: 2004054402
Certified Pre-Owned: No
Listed since: 09-09-2025 - $27,998fair price$257 below market
- 92,445 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from VA to IA*
Close
Located in Newport News, VA / 961 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA6JC023219
Stock: 27844353
Certified Pre-Owned: No - New Listing$50,998fair price$905 above market
- 17,441 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from CO to IA*
Close
Located in Colorado Springs, CO / 613 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA4NC088830
Stock: 27630420
Certified Pre-Owned: No - $36,975fair price$738 below market
- 31,534 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Hiland Toyota (164 mi away)
Close
Located in Moline, IL / 164 miles away from Des Moines, IA
This vehicle won't be on the lot long! It just arrived on our lot, and surely won't be here long! With just over 30,000 miles on the odometer, this 4 ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA7JC028168
Stock: T528168
Certified Pre-Owned: No
Listed since: 09-12-2025 - $45,795fair price$1,377 below market
- 38,950 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- The Car Buying Center (240 mi away)
Close
Located in Loretto, MN / 240 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDAXNC088959
Stock: 088959
Certified Pre-Owned: No
Listed since: 09-03-2025 - $33,644fair price$835 above market
- 60,379 miles
- No accidents, 3 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Hendrick Lexus Kansas City (187 mi away)
Close
Located in Merriam, KS / 187 miles away from Des Moines, IA
EPA 28 MPG Hwy/31 MPG City! LOW MILES - 60,379! Heated Seats, Moonroof, Nav System, Lane Keeping Assist, Keyless Start, iPod/MP3 Input, Hybrid, All Wh...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA5JC021459
Stock: P21459
Certified Pre-Owned: No
Listed since: 08-01-2025 - New Listing$21,600good price$825 below market
- 120,120 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 30 City / 28 Hwy MPG
- Lexus of Milwaukee (310 mi away)
Close
Located in Milwaukee, WI / 310 miles away from Des Moines, IA
Rare Hard To Find RX450H Hybrid!Triple Beam Headlights!Heated & Cooled Seats!Recent Arrival! CARFAX One-Owner. Gray 2016 Lexus RX 4D Sport Utili...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (30 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA1GC005915
Stock: PWS8102A
Certified Pre-Owned: No
Listed since: 09-19-2025 - New Listing
- 41,532 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from NC to IA*
Close
Located in Charlotte, NC / 826 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA8NC077569
Stock: 26262259
Certified Pre-Owned: No
Showing 64 - 84 out of 184 listings
Consumer Reviews for the Lexus RX 450h
Read recent reviews for the Lexus RX 450h
My Atomic Silver Ride!
markh, 11/25/2019
2020 Lexus RX 450h F SPORT Performance 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I graduated from a 2017 RX 350 to the 2020 RX 450h Performance F Sport and love it! I love the feel and sound when I put it in Sport mode, but most of the time I keep it in Eco Mode for improved mileage. In Sport mode the gas pedal is soft, whereas in Eco mode it seems as the pedal is harder to push, saving fuel? The car is very similar to my 2017 inside, except the speedometer … area. There is no space under the back seats to stick my car wash rags or umbrella since the battery is in that area. (not a problem). The RX 450h has a smaller fuel tank then the RX 350 but I am getting around a 100 miles more between fill ups with the RX 450h. The only drawback is the RX 450h does require 93 octane which compared to an RX 350 that burns 87 octane there is only a slight cost savings on fuel. Currently I am getting exactly what the estimated mileage on the sticker says....
Used 2022 Lexus RX 450h in Des Moines, IA Values
Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $33,752 | $34,865 | $36,023 |
| Clean | $33,302 | $34,382 | $35,505 |
| Average | $32,553 | $33,577 | $34,642 |
| Rough | $31,579 | $32,531 | $33,520 |
The average list price of a used 2022 Lexus RX 450h in Des Moines, Iowa is $40,326. The average mileage on a used Lexus RX 450h 2022 for sale in Des Moines, Iowa is 53,472. Based on the average mileage of 53,472 for used 2022 Lexus RX 450h for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Des Moines, Iowa to be $32,553.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.