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135 listings
  • $35,998
    great price
    $4,599 below market
    • 70,338 miles
    • No accidents, 2 owners, personal use only
    • 20 City / 28 Hwy MPG
    • Toyota of Lancaster (146 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Lancaster, CA / 146 miles away from San Diego, CA

    Clean CARFAX.2021 Lexus IS 350 F SPORT20/28 City/Highway MPGAwards:* ALG Residual Value Awards, Residual Value AwardsWe make it easy for you with a ri...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B26M5041779
    Stock: 4256
    Certified Pre-Owned: No
    Listed since: 09-01-2025

  • $37,152
    good price
    $5,064 below market
    • 52,727 miles
    • No accidents, 1 owner, personal use
    • 19 City / 26 Hwy MPG
    • Culver City Chevrolet (112 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Culver City, CA / 112 miles away from San Diego, CA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E20M5022463
    Stock: P50509
    Certified Pre-Owned: No
    Listed since: 06-24-2025

    • 48,721 miles
    • Insurance loss reported, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Convoy Motors (5 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in National City, CA / 5 miles away from San Diego, CA

    2021 Lexus IS IS 350 F SPORT SEDAN 4D THIS IS PRICED WAY BELOW THE MARKET VALUE BECAUSE IT HAS SALVAGED TITLE V6, 3.5-Liter Engine with 8-Speed Auto...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Issue reported

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B2XM5042188
    Stock: SALVAGED042188
    Certified Pre-Owned: No
    Listed since: 09-12-2025

  • New Listing
    Stock photo**
    $36,799
    fair price
    $611 above market
    • 42,316 miles
    • 2 accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • California Motors Direct Montclair (97 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Montclair, CA / 97 miles away from San Diego, CA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B23M5039715
    Stock: M5039715A
    Certified Pre-Owned: No
    Listed since: 07-24-2025

  • New Listing
    • 85,627 miles
    • No accidents, 2 owners, corporate fleet vehicle
    • 20 City / 28 Hwy MPG
    • Driveway (156 mi away)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Oxnard, CA / 156 miles away from San Diego, CA

    CarFax No Accidents Reported,Rare Find,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyle...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: No

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B29M5041629
    Stock: M5041629P
    Certified Pre-Owned: No

    • 49,944 miles
    • No accidents, 3 owners, personal use
    • 20 City / 28 Hwy MPG
    • Sunrise Ford Fontana (94 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fontana, CA / 94 miles away from San Diego, CA

    Recent Arrival! IS 350 F SPORT, 3.5L V6 DOHC Dual VVT-i 24V, 8-Speed Automatic, Black Artificial Leather, Apple CarPlay/Android Auto.20/28 City/High...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B25M5042907
    Stock: V67885
    Certified Pre-Owned: No
    Listed since: 09-11-2025

  • Price Drop
    • 45,355 miles
    • 1 accident, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • California Motors Direct Montclair (97 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Montclair, CA / 97 miles away from San Diego, CA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B25M5044429
    Stock: M5044429
    Certified Pre-Owned: No
    Listed since: 08-18-2025

  • New Listing
    • 52,527 miles
    • 1 accident, 3 owners, personal use
    • 20 City / 28 Hwy MPG
    • Keyes Lexus (125 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Van Nuys, CA / 125 miles away from San Diego, CA

    Recent Arrival! 2021 Lexus IS 20/28 City/Highway MPG Complimentary Maintenance for one (1) year or 15,000 miles, whichever occurs first.Awards: * A...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B28M5042674
    Stock: M5042674T
    Certified Pre-Owned: No
    Listed since: 09-20-2025

  • $36,821
    great price
    $3,191 below market
    • 51,292 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Envision Toyota of West Covina (102 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in West Covina, CA / 102 miles away from San Diego, CA

    Infrared 2022 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V White w/Black w/F SPORT NuLuxe Seat Trim, 10 Speakers, 4-Wheel Di...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B2XN5051510
    Stock: 5051510P
    Certified Pre-Owned: No
    Listed since: 06-23-2025

    • 39,281 miles
    • 1 accident, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • Auto City (12 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in El Cajon, CA / 12 miles away from San Diego, CA

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B29M5044241
    Stock: 044241
    Certified Pre-Owned: No

  • New Listing
    $40,998
    good price
    $2,216 below market
    • 23,810 miles
    • 20 City / 28 Hwy MPG
    • CarMax Murrieta (57 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Murrieta, CA / 57 miles away from San Diego, CA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B20N5055095
    Stock: 27769132
    Certified Pre-Owned: No

  • Price Drop
    $41,100
    fair price
    $230 above market
    • 25,747 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • Sunrise Ford North Hollywood (122 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in North Hollywood, CA / 122 miles away from San Diego, CA

    Priced below KBB Fair Purchase Price!Detail Interior/Exterior, New Feature, IS 350 F SPORT, 3.5L V6 DOHC Dual VVT-i 24V, 8-Speed Automatic, Red Arti...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B28N5053630
    Stock: B50243
    Certified Pre-Owned: No
    Listed since: 07-22-2025

  • Price Drop
    $40,951
    fair price
    $1,403 above market
    • 33,898 miles
    • No accidents, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • Lexus of Cerritos (95 mi away)
    • Five Star Dealer
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Cerritos, CA / 95 miles away from San Diego, CA

    Power Tilt & Slide MoonroofIntuitive Park Assist W/Auto BrakingSun/MoonroofAccessory PackageDoor Edge Film By 3MLane Keeping AssistKeyless Start...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B22N5057351
    Stock: N5057351
    Certified Pre-Owned: No
    Listed since: 08-26-2025

  • $40,951
    fair price
    $1,121 above market
    • 35,208 miles
    • No accidents, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • Lexus of Cerritos (95 mi away)
    • Five Star Dealer
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Cerritos, CA / 95 miles away from San Diego, CA

    Power Tilt & Slide MoonroofIntuitive Park Assist W/Auto BrakingSun/MoonroofPremium Paint (Pj)Illuminated Door SillsCarpet Trunk MatDoor Edge Fil...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B24N5052474
    Stock: N5052474
    Certified Pre-Owned: No
    Listed since: 09-08-2025

  • $42,250
    fair price
    $1,173 above market
    • 23,858 miles
    • No accidents, 2 owners, personal use
    • 20 City / 28 Hwy MPG
    • Driveway (130 mi away)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Mission Hills, CA / 130 miles away from San Diego, CA

    Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Lane Keeping Assist,Premium So...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B2XN5055587
    Stock: N5055587P
    Certified Pre-Owned: No

  • New Listing
    $39,336
    good price
    $1,958 below market
    • 31,281 miles
    • 1 accident, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • Lexus of Cerritos (95 mi away)
    • Five Star Dealer
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Cerritos, CA / 95 miles away from San Diego, CA

    Navigation PackagePower Tilt & Slide MoonroofMemory PackageIntuitive Park Assist W/Auto BrakingSun/MoonroofPremium Paint (Pj)Navigation SystemI...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B21N5053615
    Stock: N5053615
    Certified Pre-Owned: No
    Listed since: 09-15-2025

  • $40,746
    fair price
    $902 above market
    • 42,339 miles
    • 1 accident, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • Tustin Lexus (78 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Tustin, CA / 78 miles away from San Diego, CA

    CARFAX 1-Owner, L/ Certified, Excellent Condition. Heated/Cooled Seats, Navigation, Moonroof, Satellite Radio, Premium Sound System, Back-Up Camera, P...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B21N5053548
    Stock: N5053548
    Certified Pre-Owned: Yes
    Listed since: 09-13-2025

    • 27,362 miles
    • No accidents, 1 owner, personal use only
    • 20 City / 28 Hwy MPG
    • Sterling BMW (76 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Newport Beach, CA / 76 miles away from San Diego, CA

    White 2022 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V Odometer is 10247 miles below market average! 20/28 City/Highway MPG

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: Yes

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B26N5051259
    Stock: 46416T
    Certified Pre-Owned: No
    Listed since: 08-28-2025

  • New Listing
    $36,990
    fair price
    $680 above market
    • 71,885 miles
    • 20 City / 28 Hwy MPG
    • Lexus Carlsbad (30 mi away)
    • Home delivery*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Carlsbad, CA / 30 miles away from San Diego, CA

    Infrared 2022 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V CLEAN CARFAX, LOCALLY TRADED, LOW MILES, Century 7 year 100k mile...

    AutoCheck Vehicle History Summary Unavailable.

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B28N5052686
    Stock: P40493BHA
    Certified Pre-Owned: No
    Listed since: 09-23-2025

  • New Listing
    • 39,934 miles
    • No accidents, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from NV to CA*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Las Vegas, NV / 260 miles away from San Diego, CA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: Yes

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B28L5035755
    Stock: 27068030
    Certified Pre-Owned: No

    • 32,385 miles
    • 1 accident, 1 owner, personal use
    • 20 City / 28 Hwy MPG
    • CarMax (In-stock online)
    • Transfer available from TX to CA*
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Garland, TX / 1,189 miles away from San Diego, CA

    CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...

    AutoCheck Vehicle History Summary

    Accident Free Vehicle: No

    Personal Use Only: Yes

    History Provider: AutoCheck

    Title Details: Clean Title

    Salvage Vehicle: No

    Frame Damage: No

    Theft History: No

    Lemon Status: No

    Free History Report: No

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B28L5036498
    Stock: 27691375
    Certified Pre-Owned: No

Showing 1 - 21 out of 135 listings

Consumer Reviews for the Lexus IS 350

Read recent reviews for the Lexus IS 350
Overall Consumer Rating
4.5 out of 5 stars35 Reviews
Write a vehicle reviewSee all 35 reviews
  • 5 star
    (71%)
  • 4 star
    (17%)
  • 3 star
    (6%)
  • 2 star
    (3%)
  • 1 star
    (3%)
5 out of 5 stars

2016 IS350 F Sport

Tim, 03/30/2016
2016 Lexus IS 350 4dr Sedan AWD (3.5L 6cyl 6A)
I hesitated to buy this car because of Consumer Reports rating. They did not like the car very much. Later I found their review was based on the entry level IS. My opinion is that this car is awesome. I have owned over fifty cars in my life. I am hard to please. This car accomplishes what it is supposed to do. When you factor in reliability it wins the class with little competition.
Report abuse

Used 2021 Lexus IS 350 in San Diego, CA Values

Estimated values
2021 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) with no options
ConditionTrade-InPrivate PartyDealer Retail
Outstanding$31,120$33,119$35,127
Clean$30,517$32,448$34,384
Average$29,512$31,329$33,146
Rough$28,206$29,875$31,536

The average list price of a used 2021 Lexus IS 350 in San Diego, California is $37,902. The average mileage on a used Lexus IS 350 2021 for sale in San Diego, California is 44,087. Based on the average mileage of 44,087 for used 2021 Lexus IS 350 for sale in San Diego, CA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus IS 350 2021 in San Diego, California to be $29,512.

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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.