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New Lexus RX 450h for Sale

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155 listings
  • New Listing
    2022 Lexus RX 450h Base Hybrid

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,325
    MSRP
    Matador Red Mica Color: Matador Red Mica Matador Red Mica
    Glazed Caramel premium leather Color: Glazed Caramel premium leather Glazed Caramel premium leather
    6cyl Automatic
    Reliable Lexus (236 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Heated seats
    Navigation
    +more

    Located in Springfield, MO / 236 miles away from Southaven, MS

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA3NC090358
    Stock: 090358
    Listed since: 08-11-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,235
    MSRP
    Nebula Gray Pearl Color: Nebula Gray Pearl Nebula Gray Pearl
    Black premium leather Color: Black premium leather Black premium leather
    6cyl Automatic
    Mungenast Lexus of St Louis (252 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Manchester, MO / 252 miles away from Southaven, MS

    Gray 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V Recent Arrival! 31/28 City/Highway MPG

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4NC086643
    Stock: 33009
    Listed since: 08-12-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,560
    MSRP
    Nebula Gray Pearl Color: Nebula Gray Pearl Nebula Gray Pearl
    Glazed Caramel premium leather Color: Glazed Caramel premium leather Glazed Caramel premium leather
    6cyl Automatic
    Mungenast Lexus of St Louis (252 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Manchester, MO / 252 miles away from Southaven, MS

    Gray 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V 31/28 City/Highway MPG

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA6NC089060
    Stock: L32959
    Listed since: 07-13-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $59,165
    MSRP
    Matador Red Mica Color: Matador Red Mica Matador Red Mica
    Black premium leather Color: Black premium leather Black premium leather
    6cyl Automatic
    Nalley Lexus Smyrna (323 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Heated seats
    Navigation
    +more

    Located in Smyrna, GA / 323 miles away from Southaven, MS

    Matador Red Mica 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V31/28 City/Highway MPG

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA9NC090704
    Stock: NC30J018
    Listed since: 07-07-2022

  • Advertisement
    Also Consider
    4 Offers Nearby
    2022 Lexus RX 350
    $45,570
    starting MSRP
    • 7 Colors
    • 1 Trim
    View Offers
    Edmunds data shows offers may be available near you.
  • 2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $59,835
    MSRP
    Parchment premium leather Color: Parchment premium leather Parchment premium leather
    6cyl Automatic
    Butler Lexus of South Atlanta (327 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Heated seats
    Navigation
    +more

    Located in Union City, GA / 327 miles away from Southaven, MS

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA7NC090135
    Stock: NC28I389
    Listed since: 08-06-2022

  • 2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $59,335
    MSRP
    Caviar Color: Caviar Caviar
    Black premium leather Color: Black premium leather Black premium leather
    6cyl Automatic
    Butler Lexus of South Atlanta (327 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Heated seats
    Navigation
    +more

    Located in Union City, GA / 327 miles away from Southaven, MS

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA5NC090330
    Stock: NC28J188
    Listed since: 08-09-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $66,030
    MSRP
    Eminent White Pearl Color: Eminent White Pearl Eminent White Pearl
    Glazed Caramel premium leather Color: Glazed Caramel premium leather Glazed Caramel premium leather
    6cyl Automatic
    Lexus of Wichita (444 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Heated seats
    Navigation
    +more

    Located in Wichita, KS / 444 miles away from Southaven, MS

    Delivers 28 Highway MPG and 31 City MPG! This Lexus RX delivers a Gas/Electric V-6 3.5 L/211 engine powering this Variable transmission. WIRELESS CHAR...

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA3NC090327
    Stock: 54AG267N
    Listed since: 08-10-2022

  • 2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,780
    MSRP
    Eminent White Pearl Color: Eminent White Pearl Eminent White Pearl
    6cyl Automatic
    Lexus of Merrillville (471 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Heated seats
    Sunroof/Moonroof
    +more

    Located in Merrillville, IN / 471 miles away from Southaven, MS

    0085 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V31/28 City/Highway MPG

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA6NC085106
    Stock: R0372

  • Advertisement
    Also Consider
    4 Offers Nearby
    2022 Lexus RX 350
    $45,570
    starting MSRP
    • 7 Colors
    • 1 Trim
    View Offers
    Edmunds data shows offers may be available near you.
  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,235
    MSRP
    Caviar Color: Caviar Caviar
    Glazed Caramel premium leather Color: Glazed Caramel premium leather Glazed Caramel premium leather
    6cyl Automatic
    Lexus of Orland (473 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Orland Park, IL / 473 miles away from Southaven, MS

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA3NC090442
    Stock: J1667
    Listed since: 08-15-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $58,220
    MSRP
    Atomic Silver Color: Atomic Silver Atomic Silver
    6cyl Automatic
    Lexus of Fort Wayne (495 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Fort Wayne, IN / 495 miles away from Southaven, MS

    Recent Arrival! Silver 2022 Lexus RX 450h AWD 4D Sport Utility***Many Lexus have great options like ** LEXUS ENFORM WI-FI, APPLE CARPLAY, WIRELESS CHA...

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA4NC089976
    Stock: 94063
    Listed since: 08-09-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $63,950
    MSRP
    Black premium leather Color: Black premium leather Black premium leather
    6cyl Automatic
    McGrath Lexus of Chicago (495 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Chicago, IL / 495 miles away from Southaven, MS

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA1NC086664
    Stock: N851
    Listed since: 08-11-2022

  • 2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,560
    MSRP
    Black premium leather Color: Black premium leather Black premium leather
    6cyl Automatic
    McGrath Lexus of Chicago (495 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Chicago, IL / 495 miles away from Southaven, MS

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA2NC086245
    Stock: N617
    Listed since: 05-26-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,235
    MSRP
    Black premium leather Color: Black premium leather Black premium leather
    6cyl Automatic
    McGrath Lexus of Chicago (495 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Chicago, IL / 495 miles away from Southaven, MS

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA3NC090635
    Stock: N856
    Listed since: 08-12-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $62,755
    MSRP
    Caviar Color: Caviar Caviar
    Glazed Caramel premium leather Color: Glazed Caramel premium leather Glazed Caramel premium leather
    6cyl Automatic
    Fields Lexus Glenview (506 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Glenview, IL / 506 miles away from Southaven, MS

    Caviar 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24VFields Lexus of Glenview is pumped up to offer this outstanding 2022 Lexus RX 450h in Caviar ...

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA8NC086712
    Stock: L22778
    Listed since: 08-14-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,325
    MSRP
    Nebula Gray Pearl Color: Nebula Gray Pearl Nebula Gray Pearl
    Parchment premium leather Color: Parchment premium leather Parchment premium leather
    6cyl Automatic
    Fields Lexus Glenview (506 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Glenview, IL / 506 miles away from Southaven, MS

    Nebula Gray Pearl 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24VFields Lexus of Glenview is honored to offer this fantastic-looking 2022 Lexus RX ...

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA3NC090425
    Stock: L22776
    Listed since: 08-11-2022

  • 2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,650
    MSRP
    Nori Green Pearl Color: Nori Green Pearl Nori Green Pearl
    Black premium leather Color: Black premium leather Black premium leather
    6cyl Automatic
    Fields Lexus Glenview (506 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Glenview, IL / 506 miles away from Southaven, MS

    Nori Green Pearl 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24VFields Lexus of Glenview is honored to offer this attractive-looking 2022 Lexus RX ...

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA3NC33P345
    Stock: L22741
    Listed since: 08-01-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,565
    MSRP
    Parchment premium leather Color: Parchment premium leather Parchment premium leather
    6cyl Automatic
    Lexus of Highland Park (513 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Highland Park, IL / 513 miles away from Southaven, MS

    Pear 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24VRecent Arrival! 31/28 City/Highway MPGLexus of Highland Park is a truly family-owned and operat...

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA4NC090496
    Stock: 220502
    Listed since: 08-11-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,065
    MSRP
    Nebula Gray Pearl Color: Nebula Gray Pearl Nebula Gray Pearl
    Parchment premium leather Color: Parchment premium leather Parchment premium leather
    6cyl Automatic
    Lexus of Highland Park (513 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Highland Park, IL / 513 miles away from Southaven, MS

    Gray Pearl 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24VRecent Arrival! 31/28 City/Highway MPGLexus of Highland Park is a truly family-owned and ...

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA5NC090524
    Stock: 220503
    Listed since: 08-11-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $55,535
    MSRP
    Parchment premium leather Color: Parchment premium leather Parchment premium leather
    6cyl Automatic
    Jim Hudson Lexus (517 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Columbia, SC / 517 miles away from Southaven, MS

    01h9 2022 Lexus RX 450h AWD eCVT 3.5L V6 DOHC VVT-i 24V AWD, Parchment Nuluxe.10 Million Meals fed through Harvest Hope right here in the Midlands. Do...

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2HGMDA3NC090407
    Stock: C32310
    Listed since: 08-10-2022

  • 2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $62,660
    MSRP
    Atomic Silver Color: Atomic Silver Atomic Silver
    Black premium leather Color: Black premium leather Black premium leather
    6cyl Automatic
    Germain Lexus of Dublin (518 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Dublin, OH / 518 miles away from Southaven, MS

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA5NC088692
    Stock: 51494
    Listed since: 08-04-2022

  • New Listing
    2022 Lexus RX 450h Base Hybrid
    Stock photo © EVOX Images **

    2022 Lexus RX 450h
    Base Hybrid 4dr SUV

    $64,705
    MSRP
    Nebula Gray Pearl Color: Nebula Gray Pearl Nebula Gray Pearl
    Parchment premium leather Color: Parchment premium leather Parchment premium leather
    6cyl Automatic
    Germain Lexus of Easton (523 mi away)
    AWD/4WD
    Back-up camera
    Bluetooth
    Keyless Entry/Start
    Upgraded Headlights
    +more

    Located in Columbus, OH / 523 miles away from Southaven, MS

    Gray Pearl AWD Automatic 3.5L V6 DOHC VVT-i 24VRecent Arrival! 31/28 City/Highway MPG2022 Lexus RX 450h

    Features and Specs:

    30 Combined MPG (31 City/28 Highway)

    Listing Information:

    VIN: 2T2JGMDA2NC090223
    Stock: 46929
    Listed since: 08-15-2022

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RX 450h Reviews & Specs

Consumer Reviews for the Lexus RX 450h

Read recent reviews for the Lexus RX 450h
Overall Consumer Rating
4.7 out of 5 stars3 Reviews
Write a reviewSee all 3 reviews
  • 5
    (67%)
  • 4
    (33%)
5 out of 5 stars
Best SUV
Mike ,02/05/2022
F SPORT Handling 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
I have a 2021 RX 450h F sport, its The best car I ever owned... Had Audi, Mercedes, all money pits from New!! Good job Lexus!!!
Report abuse
TrimMPGEngineStarting Price
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)31 - 286-cylinders (hybrid)$55,535

More about the Lexus RX 450h

Edmunds has 155 new Lexus RX 450hs for sale near you, including a 2022 RX 450h Base SUV and a 2022 RX 450h Base SUV ranging in price from $55,535 to $66,030.

How much is a new 2022 Lexus RX 450h in Southaven, MS?

A new 2022 Lexus RX 450h starts at $55,535 (including destination charge) in Southaven, MS. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next. Learn more

How much does a 2022 Lexus RX 450h SUV cost in Southaven, MS?

A new 2022 Lexus RX 450h SUV starts at $55,535 in Southaven, MS. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds. Learn more
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