New Cars, Used Cars, Car Reviews and Pricing | Edmunds

77 listings

Sort by:

2022 Lexus RX 350
F SPORT 4dr SUV
$45,499
fair price
$1,266 above market
- 22,159 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Acura of Westmont (88 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
Close
Located in Westmont, IL / 88 miles away from Niles, MI
Silver 2022 Lexus RX 350 F Sport AWD 8-Speed Automatic 3.5L V6 DOHC 24V. $4035 IN ADDED OPTIONS! **ONE OWNER**, **ACCIDENT FREE CARFAX**, **AWD**, *N...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5NC339886
Stock: PJ12450
Certified Pre-Owned: No
Listed since: 07-18-2025
Price Drop
Certified 2022 Lexus RX 350
Base 4dr SUV
$39,995
good price
$2,294 below market
- 41,863 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Arlington (92 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
Close
Located in Arlington Heights, IL / 92 miles away from Niles, MI
Discover the epitome of luxury and performance in this stunning 2022 Lexus RX 350. This exceptional SUV is a true testament to Lexus' commitment to cr...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC346778
Stock: AL4150A
Certified Pre-Owned: Yes
Listed since: 08-16-2025
Price Drop
Certified 2022 Lexus RX 350
Base 4dr SUV
$41,990
fair price
$646 below market
- 39,633 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Merrillville (63 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
Close
Located in Merrillville, IN / 63 miles away from Niles, MI
UNLIMITED MILE COMPREHENSIVE WARRANTY THRU 02/05/2028!, PANORAMIC VIEW MONITOR!, NAVIGATION!, BLIND SPOT MONITOR!, LEXUS SAFETY SYSTEM PLUS!, HEATED S...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC331979
Stock: LM04361
Certified Pre-Owned: Yes
Listed since: 05-23-2025
Price Drop
Certified 2022 Lexus RX 350
Base 4dr SUV
$40,295
good price
$1,754 below market
- 56,482 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Woodfield Lexus (94 mi away)
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
- Blind Spot Monitorin...
Close
Located in Schaumburg, IL / 94 miles away from Niles, MI
**ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, ** Local Trade**, **Lexus Safety System Plus**, ** Lane De...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA8NC227162
Stock: 251194A
Certified Pre-Owned: Yes
Listed since: 08-06-2025
2022 Lexus RX 350
Base 4dr SUV
$35,990
good price
$1,238 below market
- 80,453 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (72 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Chicago, IL / 72 miles away from Niles, MI
Recent Arrival! Caviar 2022 Lexus RX 350 **APPLE CARPLAY & ANDROID AUTO, **NAVIGATION, **HEATED & COOLED SEATS, **HEATED STEERING WHEEL, **SUNROOF/MOO...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA2NC368000
Stock: S1120B
Certified Pre-Owned: No
Listed since: 06-28-2025
Price Drop
2022 Lexus RX 350
F SPORT 4dr SUV
$41,995
fair price
$548 below market
- 41,648 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Mercedes-Benz of Westmont (88 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
Close
Located in Westmont, IL / 88 miles away from Niles, MI
12.3" Navigation SystemIntuitive Parking Assist W/Panoramic View MonitorTilt & Slide MoonroofHeated & Ventilated Front SeatsColor Heads-Up Display...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDA5NC362245
Stock: NC362245
Certified Pre-Owned: No
Listed since: 08-14-2025
Certified 2022 Lexus RX 350
Base 4dr SUV
$45,995
fair price
$748 above market
- 27,929 miles
- No accidents, 2 owners, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Fields Lexus Glenview (81 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Glenview, IL / 81 miles away from Niles, MI
SAVE THOUSANDS VERSUS NEW on this one-owner, clean CARFAX, LOW MILEAGE, Atomic Silver / Parchment RX350 AWD! Meticulously maintained and exquisitely e...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC321649
Stock: P1786
Certified Pre-Owned: Yes
Listed since: 08-18-2025
Certified 2022 Lexus RX 350
Base 4dr SUV
$39,995
fair price
$421 above market
- 76,989 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Fields Lexus Glenview (81 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Glenview, IL / 81 miles away from Niles, MI
Recently received and ready for immediate delivery is this one-owner, clean CARFAX, GORGEOUS, PERFECTLY MAINTAINED, Atomic Silver / Black RX350 AWD! M...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC312596
Stock: L251016A
Certified Pre-Owned: Yes
Listed since: 07-31-2025
Certified 2022 Lexus RX 350
Base 4dr SUV
$41,988
fair price
$324 below market
- 50,506 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (72 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Chicago, IL / 72 miles away from Niles, MI
Recent Arrival! Nightfall Mica 2022 Lexus RX 350 **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES, **APPL...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC356143
Stock: S1615A
Certified Pre-Owned: Yes
Listed since: 08-18-2025
Certified 2022 Lexus RX 350
Base 4dr SUV
$43,995
- 42,765 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (94 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
Close
Located in Schaumburg, IL / 94 miles away from Niles, MI
**ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, **Lexus Safety System Plus**, ** Lane Departure Warning, *...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA1NC322979
Stock: Q3671
Certified Pre-Owned: Yes
Listed since: 08-19-2025
Certified 2022 Lexus RX 350
F SPORT 4dr SUV
$43,995
- 59,654 miles
- No accidents, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Fields Lexus Glenview (81 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
Close
Located in Glenview, IL / 81 miles away from Niles, MI
CARFAX One-Owner. Clean CARFAX.Certified. L/Certified Details: * CERTIFIED WARRANTY: Unlimited-mileage warranty up to 6 years. Balance of new car...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2SZMDAXNC326003
Stock: P1785
Certified Pre-Owned: Yes
Listed since: 08-18-2025
Certified 2022 Lexus RX 350
Base 4dr SUV
$43,480
- 31,129 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (72 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
Close
Located in Chicago, IL / 72 miles away from Niles, MI
Recent Arrival! Atomic Silver 2022 Lexus RX 350 **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES, **APPLE...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: Yes
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC329282
Stock: U4708
Certified Pre-Owned: Yes
Listed since: 05-01-2025
Price Drop
Certified 2022 Lexus RX 350
Base 4dr SUV
$39,995
- 49,852 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 19 City / 26 Hwy MPG
- Woodfield Lexus (94 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Schaumburg, IL / 94 miles away from Niles, MI
**ADDITIONAL 2 YEARS/UNLIMITED MILE COMPREHENSIVE WARRANTY AND COMPLIMENTARY MAINTENANCE**, ** Local Trade**, **Lexus Safety System Plus**, ** Lane De...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2AZMDA6NC318945
Stock: 251364A
Certified Pre-Owned: Yes
Listed since: 07-31-2025
New Listing
Stock photo^**
2022 Lexus RX 350
Base 4dr SUV
Not Priced
- 38,960 miles
- 5 Seats, 19 City / 26 Hwy MPG
- Lexus of Arlington (92 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Arlington Heights, IL / 92 miles away from Niles, MI
2022 Lexus RX 350 Recent Arrival! Clean CARFAX. AWD 8-Speed Automatic 4D Sport Utility GreenWith Some Available Options Like 18" x 8" Aluminum Whee...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA8NC316211
Stock: AL4203A
Certified Pre-Owned: No
Listed since: 08-30-2025
Price Drop
2022 Lexus RX 350
F SPORT 4dr SUV w/Handling Package
$40,777
great price
$4,549 below market
- 31,195 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Old Orchard Nissan (79 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Navigation
- Sunroof/Moonroof
Close
Located in Skokie, IL / 79 miles away from Niles, MI
2022 Lexus RX 8-Speed Automatic AWD, Circuit Red Artificial Leather, 12.3" Navigation System, Auto Recirculation Air Conditioner, F SPORT Handling Pac...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2YZMDA2NC313689
Stock: Z2384
Certified Pre-Owned: No
Listed since: 12-31-2024
Price Drop
2022 Lexus RX 350
Base 4dr SUV
$33,929
great price
$5,551 below market
- 42,703 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
- AWD/4WD
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
Close
Located in Tampa, FL / 975 miles away from Niles, MI
CarFax No Accidents Reported,CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA7NC336644
Stock: NC336644T
Certified Pre-Owned: No
Price Drop
2022 Lexus RX 350
Base 4dr SUV
$38,990
good price
$2,163 below market
- 52,277 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Kansas City, MO / 475 miles away from Niles, MI
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDAXNC310524
Stock: 2003946434
Certified Pre-Owned: No
Listed since: 08-19-2025
Price Drop
2022 Lexus RX 350
Base 4dr SUV
$36,144
great price
$4,596 below market
- 28,610 miles
- No accidents, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Wesley Chapel, FL / 962 miles away from Niles, MI
CarFax No Accidents Reported,CarFax 1-Owner,Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA1NC252985
Stock: NC252985
Certified Pre-Owned: No
2022 Lexus RX 350
Base 4dr SUV
$36,902
good price
- 35,483 miles
- 1 accident, 1 owner, personal use
- 5 Seats, 20 City / 27 Hwy MPG
- Driveway (In-stock online)
- Home delivery*
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Rockwall, TX / 828 miles away from Niles, MI
Apple CarPlay,Back-Up Camera,Blind Spot Monitor,Bluetooth,Brake Assist,Heated Seats,Heated Steering Wheel,Keyless Start,Lane Keeping Assist,Remote Sta...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
23 Combined MPG (20 City/27 Highway)
Listing Information:
VIN: 2T2HZMAA9NC254936
Stock: NC254936P
Certified Pre-Owned: No
Price Drop
2022 Lexus RX 350
Base 4dr SUV
$42,495
good price
$1,555 below market
- 28,468 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 19 City / 26 Hwy MPG
- Gurley Leep Ford Lincoln (13 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in South Bend, IN / 13 miles away from Niles, MI
AWD ** THIS VEHICLE IS BACKED BY A 12 MONTH 12,000 MILE POWERTRAIN WARRANTY **, **ONE OWNER**, **LOCAL TRADE**, **NO ACCIDENTS**, **AWD**, **HEATED AN...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA5NC322936
Stock: F7N322936
Certified Pre-Owned: No
Listed since: 07-08-2025
Price Drop
2022 Lexus RX 350
Base 4dr SUV
$39,873
great price
$3,351 below market
- 19,249 miles
- 1 accident, 1 owner, corporate fleet vehicle
- 5 Seats, 19 City / 26 Hwy MPG
- Signature Auto Enterprises (96 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Sunroof/Moonroof
- Keyless Entry/Start
Close
Located in Schaumburg, IL / 96 miles away from Niles, MI
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: No
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: 2T2HZMDA4NC314293
Stock: P61268
Certified Pre-Owned: No
Listed since: 08-20-2025

Showing 1 - 21 out of 77 listings

2022 Lexus RX 350 Review

Applied Filters3Active

Location

Search radius100 miles

Home delivery available
Only show local listings

Make & Model

Year

New / Used

Price & Payments

Price Rating

Body Type

Trim

Mileage

Accidents & History

Engine & Drivetrain

Exterior Color

Interior Color

Total Seating

Edmunds Review

Features

Options & Packages

MPG

Listing Details

* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.

Join Edmunds

Receive pricing updates, shopping tips & more!