Skip to FiltersReport abuse
211 listings
- New Listing$48,800fair price$1,348 above market
- 33,777 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Tom Wood Volkswagen (409 mi away)
Close
Located in Indianapolis, IN / 409 miles away from Des Moines, IA
2022 Lexus RX 450h Clean CARFAX. Odometer is 7837 miles below market average! *LIFETIME POWERTRAIN COVERAGE*, *LEATHER SEATS*, *HEATED FRONT SEATS*, *...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA3NC087556
Stock: VIP087556
Certified Pre-Owned: No
Listed since: 06-03-2025 - New Listing
- 17,884 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Maplewood (238 mi away)
Close
Located in Maplewood, MN / 238 miles away from Des Moines, IA
3.5L V6 DOHC VVT-i 24V, AWD, Glazed Caramel w/Semi-Aniline Seat Trim, 18" Aluminum Wheels, 3.54 Axle Ratio, 4-Wheel Disc Brakes, 9 Speakers, ABS brake...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA5NC079796
Stock: PJM19431
Certified Pre-Owned: No
Listed since: 06-04-2025 - 36,029 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- McGrath Lexus of Chicago (307 mi away)
Close
Located in Chicago, IL / 307 miles away from Des Moines, IA
Recent Arrival! Ultra White 2022 Lexus RX 450h F Sport **L/CERTIFIED BY LEXUS, **2 YRS & UNLIMITED MILE WARRANTY W/ YOUR NEXT 4 RECOMMENDED SERVICES, ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA7NC087347
Stock: U4706
Certified Pre-Owned: Yes
Listed since: 04-30-2025- 31,714 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Zeigler Subaru of Lafayette (362 mi away)
Close
Located in Lafayette, IN / 362 miles away from Des Moines, IA
Priced below KBB Fair Purchase Price! 2022 Lexus Eminent White Pearl AWD RX 450h eCVT Odometer is 6429 miles below market average! Heated & Ventilated...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA4NC072479
Stock: 3930LP
Certified Pre-Owned: No
Listed since: 04-01-2025- Price Drop
- 52,818 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Maplewood (238 mi away)
Close
Located in Maplewood, MN / 238 miles away from Des Moines, IA
L/Certified by Lexus, CarFax One Owner and No Accidents, AWD, F-Sport, Apple CarPlay, Android Auto, Heated and Ventilated Front Seats, Heated Steering...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA6NC083337
Stock: PJR19415
Certified Pre-Owned: Yes
Listed since: 05-12-2025 - New Listing
- 46,886 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax Louisville (485 mi away)
Close
Located in Louisville, KY / 485 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA2NC078801
Stock: 26483002
Certified Pre-Owned: No - New Listing
- 62,593 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Carvana (In-stock online)
- Home delivery*
Close
Located in Dallas, TX / 633 miles away from Des Moines, IA
At Carvana, we go miles beyond the extra mile. That's why we provide you with a convenient, fast, and hassle-free car buying experience that puts you ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA7JC022421
Stock: 2003775513
Certified Pre-Owned: No
Listed since: 06-03-2025 - New Listing
- 2,266 miles
- 5 Seats, 31 City / 28 Hwy MPG
- Woodfield Lexus (286 mi away)
Close
Located in Schaumburg, IL / 286 miles away from Des Moines, IA
Recent Arrival! Clean CARFAX. Dark Blue 2022 Lexus RX 450h 4D Sport Utility 3.5L V6 DOHC VVT-i 24V eCVT AWDShopping at Woodfield Lexus is car buyin...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2HGMDA1NC073038
Stock: Q3654
Certified Pre-Owned: No
Listed since: 06-05-2025 - 93,400 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Acura of Omaha (134 mi away)
Close
Located in Omaha, NE / 134 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCAXJC022302
Stock: A13763B
Certified Pre-Owned: No
Listed since: 05-30-2025- 49,469 miles
- No accidents, 2 owners, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- McGrath Lexus of Westmont (291 mi away)
Close
Located in Westmont, IL / 291 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA9JC028592
Stock: P16448
Certified Pre-Owned: No
Listed since: 05-15-2025- New Listing
- 31,491 miles
- 5 Seats, 31 City / 28 Hwy MPG
- Poquet Auto Sales (234 mi away)
Close
Located in Golden Valley, MN / 234 miles away from Des Moines, IA
NEW ARRIVAL - Cold Weather Pkg, Navigation, Panoramic Roof, NuLuxe, Heated & Ventilated Front Seats, Heated Steering Wheel, Adaptive Cruise, BLIS, Lan...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2YGMDA9LC055478
Stock: 24252035
Certified Pre-Owned: No
Listed since: 05-02-2025 - 58,993 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- McGrath Lexus of Westmont (291 mi away)
Close
Located in Westmont, IL / 291 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA8JC023111
Stock: D2427A
Certified Pre-Owned: No
Listed since: 05-17-2025- New Listing
- 15,570 miles
- 5 Seats, 31 City / 28 Hwy MPG
- Lexus of Arlington (290 mi away)
Close
Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
Certified. 2022 Lexus RX 450h Automatic, AWD/4WD, Backup Camera, BlindSpot Detection, Bluetooth, Cooled Seats, Hard to find Vehicle this nice for this...
AutoCheck Vehicle History Summary Unavailable.
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2JGMDA6NC081816
Stock: AL3971A
Certified Pre-Owned: Yes
Listed since: 06-05-2025 - 76,171 miles
- 1 accident, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- Toyota of Grand Rapids (418 mi away)
Close
Located in Grand Rapids, MI / 418 miles away from Des Moines, IA
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA7JC027702
Stock: T8807
Certified Pre-Owned: No
Listed since: 04-17-2025- New Listing$24,998great price$3,475 below market
- 103,175 miles
- 2 accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from FL to IA*
Close
Located in Jacksonville, FL / 1,028 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA0KC033505
Stock: 27300064
Certified Pre-Owned: No - $29,600good price$2,078 below market
- 103,014 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Serra BMW Champaign (299 mi away)
Close
Located in Savoy, IL / 299 miles away from Des Moines, IA
The 2019 Lexus RX 450h is the perfect blend of luxury, performance, and efficiency. With its powerful hybrid system, exceptional fuel economy, and pre...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA0KC033956
Stock: PP4164
Certified Pre-Owned: No
Listed since: 05-12-2025 - Price Drop$33,106fair price$1,553 below market
- 69,614 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Hendrick Lexus Kansas City (189 mi away)
Close
Located in Merriam, KS / 189 miles away from Des Moines, IA
3 month / 3k mile Hendrick Affordable Warranty, Very well maintained, we have the records to prove it! FUEL EFFICIENT 28 MPG Hwy/31 MPG City! Clean, L...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCAXKC038274
Stock: P38274
Certified Pre-Owned: No
Listed since: 03-22-2025 - New Listing$35,998fair price$419 below market
- 53,069 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from NY to IA*
Close
Located in Rochester, NY / 820 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA5KC036447
Stock: 26948559
Certified Pre-Owned: No - $37,998fair price$1,176 below market
- 43,215 miles
- No accidents, 1 owner, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- CarMax (In-stock online)
- Transfer available from LA to IA*
Close
Located in Baton Rouge, LA / 788 miles away from Des Moines, IA
CarMax values transparency and wants you to love your next car, not settle on it. Certain vehicles may have unrepaired safety recalls. Check nhtsa.gov...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA8KC038757
Stock: 27322637
Certified Pre-Owned: No - $36,000fair price$370 below market
- 49,785 miles
- No accidents, 2 owners, personal use
- 5 Seats, 31 City / 28 Hwy MPG
- Nelson Automotive (293 mi away)
Close
Located in Mt Prospect, IL / 293 miles away from Des Moines, IA
There's nothing else quite like our 2019 Lexus RX 450h AWD brought to you in Eminent White Pearl! Motivated by a 3.5 Liter Atkinson-Cycle V6 combined ...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA1KC037255
Stock: 037255
Certified Pre-Owned: No
Listed since: 04-11-2025 - $29,999fair price$12 below market
- 95,502 miles
- No accidents, 1 owner, personal use only
- 5 Seats, 31 City / 28 Hwy MPG
- DART Motors LLC (281 mi away)
Close
Located in Mchenry, IL / 281 miles away from Des Moines, IA
Dart Motors | 905 IL-120 | Mchenry, IL 60051 | (2**) 4**-1*** | https://www.dart-motors.com
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
30 Combined MPG (31 City/28 Highway)
Listing Information:
VIN: 2T2BGMCA1KC035781
Stock: 1133
Certified Pre-Owned: No
Listed since: 04-12-2024
Showing 127 - 147 out of 211 listings
Consumer Reviews for the Lexus RX 450h
Read recent reviews for the Lexus RX 450h
Very pleased with this car after nearly 8 years!
Happy Lexus Owner, 04/08/2018
2010 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT)
We bought our RX450h new and have driven it daily since. It is not a car for the performance oriented driver. It is a room, comfortable cruiser that gets impressive gasoline mileage in town. On the highway it is smooth and quiet. The hybrid drive has worked great, and we've had no problems with the system. After 70K miles, I can report only one significant mechanical problem, which could … very well have been catastrophic. An oil hose burst and the car leaked oil all over our garage a driveway. Fortunately, I discovered it in time before the car was driven a significant distance. The local Lexus dealer replaced it for free. This was not an isolated incident with the model... there are quite a few similar cases posted on internet forums. Why the Lexus dealer didn't recall and replace it earlier is a mystery. If you own this car or buy one used, make sure your mechanic checks all of the oil hoses! Otherwise, it's a great (if boring) car. We will pass it down to our teenage daughter soon.
Used 2022 Lexus RX 450h in Des Moines, IA Values
Estimated values
2022 Lexus RX 450h 4dr SUV AWD (3.5L 6cyl gas/electric hybrid CVT) with no options
| Condition | Trade-In | Private Party | Dealer Retail |
|---|---|---|---|
| Outstanding | $30,359 | $31,765 | $33,229 |
| Clean | $29,955 | $31,325 | $32,752 |
| Average | $29,281 | $30,591 | $31,955 |
| Rough | $28,404 | $29,638 | $30,920 |
The average list price of a used 2022 Lexus RX 450h in Des Moines, Iowa is $41,040. The average mileage on a used Lexus RX 450h 2022 for sale in Des Moines, Iowa is 53,640. Based on the average mileage of 53,640 for used 2022 Lexus RX 450h for sale in Des Moines, IA and using an average vehicle condition rating, which means the vehicle may have a few mechanical and/or cosmetic problems and may require a considerable amount of reconditioning, we appraise the average trade-in value of a used Lexus RX 450h 2022 in Des Moines, Iowa to be $29,281.
Filters
Skip to ResultsApplied Filters4Active
Make & Model
Year
New / Used
Price & Payments
Price Rating
Body Type
Trim
Mileage
Accidents & History
Engine & Drivetrain
Exterior Color
Interior Color
Total Seating
Edmunds Review
Features
Options & Packages
MPG
* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.