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    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of San Francisco (1,927 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in San Francisco, CA / 1,927 miles away from Picayune, MS

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB3SA325007
    Stock: 62859
    Listed since: 01-15-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of San Francisco (1,927 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Francisco, CA / 1,927 miles away from Picayune, MS

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB9SA322841
    Stock: 62782
    Listed since: 12-30-2024

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of San Francisco (1,927 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Francisco, CA / 1,927 miles away from Picayune, MS

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GBXSA325604
    Stock: 62872
    Listed since: 01-16-2025

    • Exterior color: Selenite Grey MetallicSelenite Grey Metallic
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of San Francisco (1,927 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Francisco, CA / 1,927 miles away from Picayune, MS

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB3SA319090
    Stock: 62506
    Listed since: 11-18-2024

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of San Francisco (1,927 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Francisco, CA / 1,927 miles away from Picayune, MS

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB8SA322992
    Stock: 62741
    Listed since: 12-20-2024

    • Exterior color: MANUFAKTUR Mystic Blue MetallicMANUFAKTUR Mystic Blue Metallic
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • Mercedes-Benz of San Francisco (1,927 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Francisco, CA / 1,927 miles away from Picayune, MS

    Features and Specs:

    Listing Information:

    VIN: W1K6G6KB8SA315803
    Stock: 62504
    Listed since: 11-18-2024

    • Mercedes-Benz of San Francisco (1,927 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Francisco, CA / 1,927 miles away from Picayune, MS

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB1SA323414
    Stock: 62666
    Listed since: 12-11-2024

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Medford (1,999 mi away)5 out of 5 stars(1)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Medford, OR / 1,999 miles away from Picayune, MS

    'Burmester is a registered trademark of Burmester Audiosysteme GmbH, Berlin, Germany.', 4.0L V8, 4MATIC , Macchiato Beige/Magma Gray Nappa Leather. 20...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB1SA328133
    Stock: SA328133
    Listed since: 03-06-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Silver Grey/Black premium leatherSilver Grey/Black premium leather
    • Mercedes-Benz of Medford (1,999 mi away)5 out of 5 stars(1)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Medford, OR / 1,999 miles away from Picayune, MS

    $7,500 Lease Bonus cash, 4.0L V8, 4MATIC , Silver Grey/Black Leather. 2025 Mercedes-Benz S-Class S 63 E AMG 4MATIC 9-Speed Automatic 4.0L V8 MANUFAKTU...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB9SA318090
    Stock: SA318090
    Listed since: 11-14-2024

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • Mercedes-Benz of Medford (1,999 mi away)5 out of 5 stars(1)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Medford, OR / 1,999 miles away from Picayune, MS

    PLUG-IN HYBRID, $7,500 Lease Bonus Cash, I6, 4MATIC , Sienna Brown/Black Nappa Leather. 2025 Mercedes-Benz S-Class S 580e 4MATIC 9-Speed Automatic I6 ...

    Features and Specs:

    Listing Information:

    VIN: W1K6G6KB6SA317288
    Stock: SA317288
    Listed since: 11-06-2024

    • Exterior color: Nautical Blue MetallicNautical Blue Metallic
    • Interior color: Silver Grey/Black premium leatherSilver Grey/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Eugene (2,039 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Eugene, OR / 2,039 miles away from Picayune, MS

    Whether it’s your first time visiting our dealership or you’re a loyal returning client, you can always count on us to provide an exceptional experien...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GBXSA327272
    Stock: 25M019
    Listed since: 11-26-2024

    • Exterior color: MANUFAKTUR Signature Moonlight White MagnoMANUFAKTUR Signature Moonlight White Magno
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Eugene (2,039 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Eugene, OR / 2,039 miles away from Picayune, MS

    Whether it’s your first time visiting our dealership or you’re a loyal returning client, you can always count on us to provide an exceptional experien...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB6SA329908
    Stock: 25M020
    Listed since: 03-23-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Eugene (2,039 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Eugene, OR / 2,039 miles away from Picayune, MS

    Whether it’s your first time visiting our dealership or you’re a loyal returning client, you can always count on us to provide an exceptional experien...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA324988
    Stock: 25M014
    Listed since: 01-20-2025

    • Exterior color: Verde Silver MetallicVerde Silver Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Bellevue (2,079 mi away)4.42 out of 5 stars(19)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Bellevue, WA / 2,079 miles away from Picayune, MS

    Amg ® Line Package,Warmth & Comfort Package,3D Technology Package,4.5 Degree Rear Axle Steering,Manufaktur Black Piano Lacquer Flowing Lines Trim,...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB8SA338108
    Stock: SA338108
    Listed since: 06-20-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Bellevue (2,079 mi away)4.42 out of 5 stars(19)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Bellevue, WA / 2,079 miles away from Picayune, MS

    Warmth & Comfort Package,3D Technology Package,Panoramic Roof,Animated Led Logo Projector,Leather Seats,Navigation System,Comfort Box,Wheels: 19" Mult...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB0SA337907
    Stock: SA337907
    Listed since: 06-16-2025

    • Exterior color: Graphite Grey MetallicGraphite Grey Metallic
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Bellevue (2,079 mi away)4.42 out of 5 stars(19)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Bellevue, WA / 2,079 miles away from Picayune, MS

    Wheels: Black 21" Amg ® Forged Cross-Spoke,Manufaktur Piano Lacquer Flowing Lines Trim,Amg ® Night Package,Red Brake Calipers,Panoramic Roof,L...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB2SA332185
    Stock: SA332185
    Listed since: 04-29-2025

  • Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Jacksonville (485 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 485 miles away from Picayune, MS

    This Mercedes-Benz AMG S 63 E 4MATIC Sedan has a strong Twin Turbo Gas/Electric V-8 4.0 L/243 engine powering this Automatic transmission. Window Grid...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB7SA329699
    Stock: BSA329699
    Listed since: 04-23-2025

  • Stock photo**
    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Jacksonville (485 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 485 miles away from Picayune, MS

    This Mercedes-Benz S 580 4MATIC Sedan has a dependable Twin Turbo Gas/Electric V-8 4.0 L/243 engine powering this Automatic transmission. Window Grid ...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB8SA328131
    Stock: BSA328131
    Listed since: 03-11-2025

  • New Listing
    Photos not available
    • Mercedes-Benz of Daytona Beach (522 mi away)
    • All Wheel Drive
    • Leather Seats
    • Heated Front Seat(s)
    • Panoramic Roof
    • Back-Up Camera
    Close

    Located in Daytona Beach, FL / 522 miles away from Picayune, MS

    2026 Mercedes-Benz 4MATIC® 4D Sedan Twin Turbo Gas/Electric V-8 4.0 L/243 4MATIC® Moonlight WhiteThis vehicle Includes the Following Features and Opti...

    Features and Specs:

    Listing Information:

    VIN: W1K6G7GB9TA344971
    Stock: TA344971
    Listed since: 06-25-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 18 City / 26 Hwy MPG
    • Mercedes-Benz of Naples (570 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Naples, FL / 570 miles away from Picayune, MS

    Obsidian 2024 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V818/27 City/Highway MPG

    Features and Specs:

    21 Combined MPG (18 City/26 Highway)

    Listing Information:

    VIN: W1K6G7GB7RA302016
    Stock: 302016
    Listed since: 08-12-2024

  • Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Fort Wayne (764 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Fort Wayne, IN / 764 miles away from Picayune, MS

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB6SA334235
    Stock: MB8832
    Listed since: 05-22-2025

Showing 757 - 777 out of 813 listings
TrimMPGEngineStarting Price
2025 Mercedes-Benz S-Class S 580 4MATIC 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric mild hybrid 9A)17 - 258-cylinders (mild hybrid)$132,090
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)N/A8-cylinders (plug-in hybrid)$194,600
2025 Mercedes-Benz S-Class S 580e 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)N/A6-cylinders (plug-in hybrid)$138,250
2026 Mercedes-Benz S-Class undefinedN/AN/AN/A
2024 Mercedes-Benz S-Class S 580 4MATIC 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric mild hybrid 9A)18 - 268-cylinders (mild hybrid)N/A

More about the Mercedes-Benz S-Class

Edmunds has 813 New Mercedes-Benz S-Classes for sale near you, including a 2025 S-Class S 580 4MATIC Sedan and a 2025 S-Class AMG S 63 E PERFORMANCE Sedan ranging in price from $132,090 to $210,415.

How much is a new 2026 Mercedes-Benz S-Class in Picayune, MS?

A new 2026 Mercedes-Benz S-Class starts at $132,090 (including destination charge) in Picayune, MS. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2026 Mercedes-Benz S-Class Sedan cost in Picayune, MS?

A new 2026 Mercedes-Benz S-Class Sedan starts at $132,090 in Picayune, MS. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2026 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE which starts at $194,600.
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