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    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 18 City / 26 Hwy MPG
    • Mercedes-Benz of Encino (1,694 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Encino, CA / 1,694 miles away from Picayune, MS

    Features and Specs:

    21 Combined MPG (18 City/26 Highway)

    Listing Information:

    VIN: W1K6G7GB0SA315521
    Stock: 3N6991
    Listed since: 10-26-2024

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Encino (1,694 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Encino, CA / 1,694 miles away from Picayune, MS

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA315627
    Stock: 3N6973
    Listed since: 10-22-2024

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Encino (1,694 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Encino, CA / 1,694 miles away from Picayune, MS

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB6SA324949
    Stock: 3N7812
    Listed since: 05-26-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Valencia (1,697 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Valencia, CA / 1,697 miles away from Picayune, MS

    Obsidian Black 2025 Mercedes-Benz S-Class AMG S 63 E 4MATIC 4D Sedan 4MATIC 9-Speed Automatic 4.0L V8Burmester is a registered trademark of Burmester ...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB6SA330956
    Stock: 4N6019
    Listed since: 04-11-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Valencia (1,697 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Valencia, CA / 1,697 miles away from Picayune, MS

    Black 2025 Mercedes-Benz S-Class S 580 4MATIC 4D Sedan 4MATIC 9-Speed Automatic 4.0L V8Burmester is a registered trademark of Burmester Audiosysteme G...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA325302
    Stock: 4N5800
    Listed since: 02-04-2025

    • Exterior color: MANUFAKTUR China BlueMANUFAKTUR China Blue
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Valencia (1,697 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Valencia, CA / 1,697 miles away from Picayune, MS

    Blue 2025 Mercedes-Benz S-Class S 580 4MATIC 4D Sedan 4MATIC 9-Speed Automatic 4.0L V8Burmester is a registered trademark of Burmester Audiosysteme Gm...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB7SA328251
    Stock: 4N6054
    Listed since: 04-18-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Valencia (1,697 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Valencia, CA / 1,697 miles away from Picayune, MS

    Black 2025 Mercedes-Benz S-Class S 580 4MATIC 4D Sedan 4MATIC 9-Speed Automatic 4.0L V8Burmester is a registered trademark of Burmester Audiosysteme G...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB8SA327335
    Stock: 4N5945
    Listed since: 03-20-2025

  • New Listing
    • Exterior color: Nautical Blue MetallicNautical Blue Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Valencia (1,697 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Valencia, CA / 1,697 miles away from Picayune, MS

    Nautical Blue 2025 Mercedes-Benz S-Class S 580 4MATIC 4D Sedan 4MATIC 9-Speed Automatic 4.0L V8Burmester is a registered trademark of Burmester Audios...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB8SA331014
    Stock: 4N6034
    Listed since: 04-16-2025

  • New Listing
    Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Valencia (1,697 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Valencia, CA / 1,697 miles away from Picayune, MS

    Black 2025 Mercedes-Benz S-Class S 580e 4MATIC 4D Sedan 4MATIC 9-Speed Automatic I6 Recent Arrival! 20/29 City/Highway MPGBurmester is a registered tr...

    Features and Specs:

    Listing Information:

    VIN: W1K6G6KB5SA320750
    Stock: 4D20750
    Listed since: 06-24-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Valencia (1,697 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Valencia, CA / 1,697 miles away from Picayune, MS

    Black 2025 Mercedes-Benz S-Class S 580 4MATIC 4D Sedan 4MATIC 9-Speed Automatic 4.0L V8Burmester is a registered trademark of Burmester Audiosysteme G...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA331679
    Stock: 4N6087
    Listed since: 04-24-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Valencia (1,697 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Valencia, CA / 1,697 miles away from Picayune, MS

    Black 2025 Mercedes-Benz S-Class S 580 4MATIC 4D Sedan 4MATIC 9-Speed Automatic 4.0L V8Burmester is a registered trademark of Burmester Audiosysteme G...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB0SA324512
    Stock: 4N5786
    Listed since: 01-16-2025

  • Stock photo**
    • Exterior color: MANUFAKTUR Night Black Magno (matte)MANUFAKTUR Night Black Magno (matte)
    • Interior color: MANUFAKTUR Signature Deep White/Black premium leatherMANUFAKTUR Signature Deep White/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Calabasas (1,703 mi away)4.88 out of 5 stars(32)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Calabasas, CA / 1,703 miles away from Picayune, MS

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB6SA337961
    Stock: SA337961
    Listed since: 06-14-2025

    • Exterior color: MANUFAKTUR China BlueMANUFAKTUR China Blue
    • Interior color: MANUFAKTUR Signature Deep White/Black premium leatherMANUFAKTUR Signature Deep White/Black premium leather
    • Mercedes-Benz of Calabasas (1,703 mi away)4.88 out of 5 stars(32)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Calabasas, CA / 1,703 miles away from Picayune, MS

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB7SA326351
    Stock: SA326351
    Listed since: 04-04-2025

    • Exterior color: MANUFAKTUR Signature Moonlight White MagnoMANUFAKTUR Signature Moonlight White Magno
    • Interior color: Carmine Red/Black premium leatherCarmine Red/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Calabasas (1,703 mi away)4.88 out of 5 stars(32)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Calabasas, CA / 1,703 miles away from Picayune, MS

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB9SA330633
    Stock: SA330633
    Listed since: 04-20-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 21 City / 31 Hwy MPG
    • Mercedes-Benz of Calabasas (1,703 mi away)4.88 out of 5 stars(32)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Calabasas, CA / 1,703 miles away from Picayune, MS

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    24 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: W1K6G6DB7RA287211
    Stock: RA287211
    Listed since: 02-21-2024

    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Calabasas (1,703 mi away)4.88 out of 5 stars(32)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Calabasas, CA / 1,703 miles away from Picayune, MS

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB4SA331734
    Stock: SA331734
    Listed since: 05-28-2025

    • Exterior color: MANUFAKTUR Night Black Magno (matte)MANUFAKTUR Night Black Magno (matte)
    • Interior color: Carmine Red/Black premium leatherCarmine Red/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Calabasas (1,703 mi away)4.88 out of 5 stars(32)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Calabasas, CA / 1,703 miles away from Picayune, MS

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA329804
    Stock: SA329804
    Listed since: 04-17-2025

  • Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Bakersfield (1,727 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Bakersfield, CA / 1,727 miles away from Picayune, MS

    NAV, Sunroof, Heated Leather Seats, Power Liftgate, Full-Time 4MATIC® All-Wheel, Turbo, Alloy Wheels, Panoramic Roof. Black exterior and Sienna Brown/...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB7SA336379
    Stock: 34426
    Listed since: 05-19-2025

  • Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 21 City / 31 Hwy MPG
    • Mercedes-Benz of Bakersfield (1,727 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Bakersfield, CA / 1,727 miles away from Picayune, MS

    Nav System, Moonroof, Heated Leather Seats, Aluminum Wheels, Full-Time 4MATIC® All-Wheel, Panoramic Roof, Power Liftgate. Black exterior and Black int...

    Features and Specs:

    24 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: W1K6G6DB8SA333196
    Stock: 34361
    Listed since: 04-28-2025

  • Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Bakersfield (1,727 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Bakersfield, CA / 1,727 miles away from Picayune, MS

    Nav System, Moonroof, Heated Leather Seats, Power Liftgate, Full-Time 4MATIC® All-Wheel, Turbo Charged Engine, Aluminum Wheels, Panoramic Roof. S 580 ...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB3SA331891
    Stock: 34480
    Listed since: 06-03-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 18 City / 26 Hwy MPG
    • Mercedes-Benz Of Reno (1,799 mi away)5 out of 5 stars(19)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Reno, NV / 1,799 miles away from Picayune, MS

    Amg ® Line Package,Warmth & Comfort Package,Manufaktur Moonlight White Metallic,Wheels: 20" Amg ® Multi Spoke,Stainless Steel Blended Black/Si...

    Features and Specs:

    21 Combined MPG (18 City/26 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA322772
    Stock: SA322772
    Listed since: 12-23-2024

Showing 652 - 672 out of 814 listings
TrimMPGEngineStarting Price
2025 Mercedes-Benz S-Class S 580 4MATIC 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric mild hybrid 9A)18 - 268-cylinders (mild hybrid)$131,715
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)N/A8-cylinders (plug-in hybrid)$193,420
2025 Mercedes-Benz S-Class S 580e 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)N/A6-cylinders (plug-in hybrid)$136,805
2024 Mercedes-Benz S-Class S 500 4MATIC 4dr Sedan AWD (3.0L 6cyl Twincharger gas/electric mild hybrid 9A)21 - 316-cylinders (mild hybrid)$130,230
2025 Mercedes-Benz S-Class S 500 4MATIC 4dr Sedan AWD (3.0L 6cyl Twincharger gas/electric mild hybrid 9A)21 - 316-cylinders (mild hybrid)$120,865

More about the Mercedes-Benz S-Class

Edmunds has 814 New Mercedes-Benz S-Classes for sale near you, including a 2025 S-Class S 500 4MATIC Sedan and a 2025 S-Class AMG S 63 E PERFORMANCE Sedan ranging in price from $120,865 to $228,545.

How much is a new 2025 Mercedes-Benz S-Class in Picayune, MS?

A new 2025 Mercedes-Benz S-Class starts at $120,865 (including destination charge) in Picayune, MS. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Mercedes-Benz S-Class Sedan cost in Picayune, MS?

A new 2025 Mercedes-Benz S-Class Sedan starts at $120,865 in Picayune, MS. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Mercedes-Benz S-Class Plug-in Hybrid which starts at $136,805.
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