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    • Exterior color: MANUFAKTUR Night Black Magno (matte)MANUFAKTUR Night Black Magno (matte)
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Laguna Niguel (1,647 mi away)1 out of 5 stars(2)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Laguna Niguel, CA / 1,647 miles away from Picayune, MS

    3D Instrument Cluster, 3D Technology Package, 4-Zone Climate Control, Adaptive Rear Lighting, Burmester® High-End 4D Surround Sound System, Chauffeur ...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB6SA337975
    Stock: A46359
    Listed since: 05-20-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Laguna Niguel (1,647 mi away)1 out of 5 stars(2)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Laguna Niguel, CA / 1,647 miles away from Picayune, MS

    AMG® Floor Mats, AMG® Line Exterior, AMG® Line Package, Animated LED Logo Projector, Night Package, Rear Deck Spoiler in Body Color, Sport Package Cod...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB8SA329733
    Stock: A46331T
    Listed since: 06-17-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Laguna Niguel (1,647 mi away)1 out of 5 stars(2)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Laguna Niguel, CA / 1,647 miles away from Picayune, MS

    AMG® Night Package, Omission Heat-Insulating Dark-Tinted Glass. Black 2025 Mercedes-Benz S-Class S 63 E AMG® 4MATIC® 9-Speed Automatic 4.0L V8Why Ch...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB4SA330762
    Stock: A46265
    Listed since: 04-18-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 48 mi est. electric range
    • 20 City / 29 Hwy MPG
    • Mercedes-Benz of Laguna Niguel (1,647 mi away)1 out of 5 stars(2)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Laguna Niguel, CA / 1,647 miles away from Picayune, MS

    AMG® Floor Mats, AMG® Line Exterior, AMG® Line Package, Animated LED Logo Projector, Sport Package Code, Wheels: 20" AMG® Multi Spoke. MANUFAKTUR Moon...

    Features and Specs:

    23 Combined MPG (20 City/29 Highway)

    Listing Information:

    VIN: W1K6G6KB3SA316048
    Stock: A46395
    Listed since: 06-20-2025

    • Exterior color: MANUFAKTUR Night Black Magno (matte)MANUFAKTUR Night Black Magno (matte)
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Anaheim (1,654 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Anaheim, CA / 1,654 miles away from Picayune, MS

    Navigation, Sunroof, Heated Leather Seats, Alloy Wheels, Turbo Charged, Full-Time 4MATIC® All-Wheel, Panoramic Roof. MANUFAKTUR Signature Night Black ...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB7SA324166
    Stock: SA324166
    Listed since: 01-15-2025

    • Exterior color: MANUFAKTUR Graphite Grey MagnoMANUFAKTUR Graphite Grey Magno
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Anaheim (1,654 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Anaheim, CA / 1,654 miles away from Picayune, MS

    Nav System, Moonroof, Heated Leather Seats, Aluminum Wheels, Turbo Charged Engine, Full-Time 4MATIC® All-Wheel, Panoramic Roof. MANUFAKTUR Graphite Gr...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB8SA323883
    Stock: SA323883
    Listed since: 01-07-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 48 mi est. electric range
    • 20 City / 29 Hwy MPG
    • Mercedes-Benz of Anaheim (1,654 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Anaheim, CA / 1,654 miles away from Picayune, MS

    NAV, Sunroof, Heated Leather Seats, Alloy Wheels, Turbo, Full-Time 4MATIC® All-Wheel, Panoramic Roof. Obsidian Black Metallic exterior and Black inter...

    Features and Specs:

    23 Combined MPG (20 City/29 Highway)

    Listing Information:

    VIN: W1K6G6KB5SA319534
    Stock: SA319534
    Listed since: 02-28-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Anaheim (1,654 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Anaheim, CA / 1,654 miles away from Picayune, MS

    Navigation, Sunroof, Heated Leather Seats, Alloy Wheels, Turbo Charged, Full-Time All-Wheel, Panoramic Roof. MANUFAKTUR Moonlight White Metallic exter...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB4SA323486
    Stock: SA323486
    Listed since: 12-16-2024

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Anaheim (1,654 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Anaheim, CA / 1,654 miles away from Picayune, MS

    NAV, Sunroof, Heated Leather Seats, Alloy Wheels, Turbo, Full-Time 4MATIC® All-Wheel, Panoramic Roof. MANUFAKTUR Moonlight White Metallic exterior and...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB3SA318980
    Stock: SA318980
    Listed since: 11-21-2024

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Silver Grey/Black premium leatherSilver Grey/Black premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Anaheim (1,654 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Anaheim, CA / 1,654 miles away from Picayune, MS

    NAV, Sunroof, Heated Leather Seats, Alloy Wheels, Turbo, Full-Time All-Wheel, Panoramic Roof. Obsidian Black Metallic exterior and Silver Grey/Black i...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB2SA318478
    Stock: SA318478
    Listed since: 10-29-2024

    • Exterior color: Rubellite Red MetallicRubellite Red Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Anaheim (1,654 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Anaheim, CA / 1,654 miles away from Picayune, MS

    Nav System, Moonroof, Heated Leather Seats, Aluminum Wheels, Turbo Charged Engine, Full-Time 4MATIC® All-Wheel, Panoramic Roof. Rubellite Red Metallic...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA321269
    Stock: SA321269
    Listed since: 12-19-2024

    • Exterior color: MANUFAKTUR Graphite GreyMANUFAKTUR Graphite Grey
    • Interior color: Silver Grey/Black premium leatherSilver Grey/Black premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Anaheim (1,654 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Anaheim, CA / 1,654 miles away from Picayune, MS

    Navigation, Moonroof, Heated Leather Seats, Power Liftgate, Full-Time All-Wheel, Turbo Charged, Aluminum Wheels, Panoramic Roof. MANUFAKTUR Signature ...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB5SA326624
    Stock: SA326624
    Listed since: 03-27-2025

    • Exterior color: MANUFAKTUR Night Black Magno (matte)MANUFAKTUR Night Black Magno (matte)
    • Interior color: Silver Grey/Black premium leatherSilver Grey/Black premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Anaheim (1,654 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Anaheim, CA / 1,654 miles away from Picayune, MS

    Navigation, Moonroof, Heated Leather Seats, Power Liftgate, Full-Time All-Wheel, Turbo Charged, Aluminum Wheels, Panoramic Roof. MANUFAKTUR Signature ...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB3SA329800
    Stock: SA329800
    Listed since: 04-15-2025

    • Exterior color: MANUFAKTUR Night Black Magno (matte)MANUFAKTUR Night Black Magno (matte)
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Anaheim (1,654 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Anaheim, CA / 1,654 miles away from Picayune, MS

    Navigation, Moonroof, Heated Leather Seats, Aluminum Wheels, Turbo Charged, Full-Time 4MATIC® All-Wheel, Panoramic Roof. MANUFAKTUR Signature Night Bl...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA322402
    Stock: SA322402
    Listed since: 01-08-2025

    • Exterior color: Graphite Grey MetallicGraphite Grey Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • House of Imports (1,665 mi away)4.65 out of 5 stars(26)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Buena Park, CA / 1,665 miles away from Picayune, MS

    Amg ® Line Package,Warmth & Comfort Package,Macchiato Beige/Black; Exclusive Nappa Leather Upholstery,10-Degree Rear Axle Steering,Manufaktur Blac...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB4SA331110
    Stock: SA331110
    Listed since: 04-21-2025

    • Exterior color: MANUFAKTUR Night Black Magno (matte)MANUFAKTUR Night Black Magno (matte)
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • House of Imports (1,665 mi away)4.65 out of 5 stars(26)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Buena Park, CA / 1,665 miles away from Picayune, MS

    Manufaktur Signature Night Black Magno,Amg ® Line Package,4.5 Degree Rear Axle Steering,3D Instrument Cluster,Wheels: 20" Amg ® Multi Spoke,Pa...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB7SA329089
    Stock: SA329089
    Listed since: 03-19-2025

    • Exterior color: BlackBlack
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • House of Imports (1,665 mi away)4.65 out of 5 stars(26)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Buena Park, CA / 1,665 miles away from Picayune, MS

    Amg ® Line Package,4.5 Degree Rear Axle Steering,Wheels: 20" Amg ® Multi Spoke,Panoramic Roof,Animated Led Logo Projector,Rear Deck Spoiler In...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GBXSA329510
    Stock: SA329510
    Listed since: 04-03-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • House of Imports (1,665 mi away)4.65 out of 5 stars(26)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Buena Park, CA / 1,665 miles away from Picayune, MS

    Rear Seat Package,Wheels: Black 21" Amg ® Forged Cross-Spoke,Black; Amg ® Exclusive Nappa Leather Upholstery,Black Microfiber Headliner,Manufa...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB4SA322354
    Stock: SA322354
    Listed since: 01-08-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • House of Imports (1,665 mi away)4.65 out of 5 stars(26)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Buena Park, CA / 1,665 miles away from Picayune, MS

    Amg ® Line Package,4.5 Degree Rear Axle Steering,Wheels: 20" Amg ® Multi Spoke,Stainless Steel Blended Black/Silver Trim,Panoramic Roof,Leathe...

    Features and Specs:

    Listing Information:

    VIN: W1K6G6KB4SA322778
    Stock: SA322778
    Listed since: 02-20-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • House of Imports (1,665 mi away)4.65 out of 5 stars(26)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Buena Park, CA / 1,665 miles away from Picayune, MS

    Panoramic Roof,Animated Led Logo Projector,Leather Seats,Navigation System,Wheels: 19" Multi-Twin Spoke W/Black Accents,Wheel Locking Bolts,Lane Keepi...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB9SA332057
    Stock: SA332057
    Listed since: 04-19-2025

    • Exterior color: MANUFAKTUR Graphite Grey MagnoMANUFAKTUR Graphite Grey Magno
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • House of Imports (1,665 mi away)4.65 out of 5 stars(26)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Buena Park, CA / 1,665 miles away from Picayune, MS

    Amg ® Line Package,Manufaktur Graphite Grey Magno,4.5 Degree Rear Axle Steering,Wheels: 20" Amg ® Multi Spoke,Panoramic Roof,Animated Led Logo...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB7SA329528
    Stock: SA329528
    Listed since: 03-21-2025

Showing 547 - 567 out of 810 listings
TrimMPGEngineStarting Price
2025 Mercedes-Benz S-Class S 580 4MATIC 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric mild hybrid 9A)17 - 258-cylinders (mild hybrid)$130,765
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)N/A8-cylinders (plug-in hybrid)$192,600
2025 Mercedes-Benz S-Class S 580e 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)20 - 296-cylinders (plug-in hybrid)$136,805

More about the Mercedes-Benz S-Class

Edmunds has 810 New Mercedes-Benz S-Classes for sale near you, including a 2025 S-Class S 580 4MATIC Sedan and a 2025 S-Class AMG S 63 E PERFORMANCE Sedan ranging in price from $130,765 to $212,415.

How much is a new 2025 Mercedes-Benz S-Class in Picayune, MS?

A new 2025 Mercedes-Benz S-Class starts at $130,765 (including destination charge) in Picayune, MS. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Mercedes-Benz S-Class Sedan cost in Picayune, MS?

A new 2025 Mercedes-Benz S-Class Sedan starts at $130,765 in Picayune, MS. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Mercedes-Benz S-Class Plug-in Hybrid which starts at $136,805.
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