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    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Birmingham (269 mi away)5 out of 5 stars(12)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Irondale, AL / 269 miles away from Picayune, MS

    4.0L V8, 4MATIC®, Macchiato Beige/Grey Leather. Want us to come to you? No problem! In case we missed a picture or a detail you would like to see of t...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA333129
    Stock: M333129
    Listed since: 05-24-2025

    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Carmine Red/Black premium leatherCarmine Red/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Birmingham (269 mi away)5 out of 5 stars(12)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Irondale, AL / 269 miles away from Picayune, MS

    4.0L V8, 4MATIC®, Carmine Red/Black Leather. Want us to come to you? No problem! In case we missed a picture or a detail you would like to see of this...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA319862
    Stock: M319862
    Listed since: 11-20-2024

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Birmingham (269 mi away)5 out of 5 stars(12)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Irondale, AL / 269 miles away from Picayune, MS

    4.0L V8, 4MATIC®, Black Leather. Want us to come to you? No problem! In case we missed a picture or a detail you would like to see of this 2025 S-Clas...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA324740
    Stock: M324740
    Listed since: 07-18-2025

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    • Exterior color: BlackBlack
    • Interior color: MANUFAKTUR Signature Nut Brown/Black premium leatherMANUFAKTUR Signature Nut Brown/Black premium leather
    • Mercedes-Benz of Huntsville (336 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 336 miles away from Picayune, MS

    Black 2025 Mercedes-Benz S-Class S 63 E AMG® 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®, MANUFAK...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB8SA321367
    Stock: S0199
    Listed since: 12-02-2024

    • Exterior color: MANUFAKTUR Graphite Grey MagnoMANUFAKTUR Graphite Grey Magno
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Huntsville (336 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 336 miles away from Picayune, MS

    Graphite Grey 2025 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®, Black...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB3SA318624
    Stock: S0198
    Listed since: 11-26-2024

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Huntsville (336 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 336 miles away from Picayune, MS

    Obsidian Black 2025 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®, Blac...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB7SA339217
    Stock: S0474
    Listed since: 06-12-2025

  • Arriving Soon
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Panoramic Roof,Leather Seats,Navigation System,Lane Keeping Assist,Keyless Start,Heads-Up Display,Cooled Front Seat(S),3D Technology Package,4.5 Degre...

    Features and Specs:

    Listing Information:

    VIN: W1K6G7GB1TA354605
    Stock: TA354605

  • Arriving Soon
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Panoramic Roof,Leather Seats,Navigation System,Lane Keeping Assist,Keyless Start,Rear Spoiler,Cooled Front Seat(S),Amg ® Line Package,Brown High-G...

    Features and Specs:

    Listing Information:

    VIN: W1K6G7GBXTA355350
    Stock: TA355350

  • Arriving Soon
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Amg ® Line Package,Sienna Brown/Black; Nappa Leather Upholstery,Wheels: 20" Amg ® Multispoke In High-Gloss Black,Panoramic Roof,Rear Deck Spoi...

    Features and Specs:

    Listing Information:

    VIN: W1K6G7GB9TA347367
    Stock: TA347367

  • Arriving Soon
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Amg ® Line Package,Black; Nappa Leather Upholstery,Panoramic Roof,Rear Deck Spoiler In Body Color,Leather Seats,Navigation System,Lane Keeping Ass...

    Features and Specs:

    Listing Information:

    VIN: W1K6G7GB9TA346932
    Stock: TA346932

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Amg ® Line Package,Wheels: 20" Amg ® Multi Spoke,Panoramic Roof,Animated Led Logo Projector,Rear Deck Spoiler In Body Color,Leather Seats,Navi...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB9SA327277
    Stock: SA327277
    Listed since: 04-25-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Amg ® Line Package,Wheels: 20" Amg ® Multi Spoke,Panoramic Roof,Animated Led Logo Projector,Rear Deck Spoiler In Body Color,Leather Seats,Navi...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA329284
    Stock: SA329284
    Listed since: 04-25-2025

  • Arriving Soon
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Panoramic Roof,Leather Seats,Navigation System,Lane Keeping Assist,Keyless Start,Cooled Front Seat(S),4.5 Degree Rear Axle Steering,Amg ® Line Pac...

    Features and Specs:

    Listing Information:

    VIN: W1K6G7GB1TA353311
    Stock: TA353311

  • Arriving Soon
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Panoramic Roof,Leather Seats,Navigation System,Lane Keeping Assist,Keyless Start,Cooled Front Seat(S),Amg ® Line Package,Brown High-Gloss Burl Wal...

    Features and Specs:

    Listing Information:

    VIN: W1K6G7GB4TA348782
    Stock: TA348782

  • Arriving Soon
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Panoramic Roof,Leather Seats,Navigation System,Lane Keeping Assist,Keyless Start,Cooled Front Seat(S),4.5 Degree Rear Axle Steering,Amg ® Line Pac...

    Features and Specs:

    Listing Information:

    VIN: W1K6G7GBXTA347815
    Stock: TA347815

  • Arriving Soon
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Amg ® Carbon Fiber Trim,Manufaktur Graphite Gray Magno,Black; Amg ® Exclusive Nappa Leather Upholstery,Panoramic Roof,Leather Seats,Navigation...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CBXTA349205
    Stock: TA349205

  • Arriving Soon
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Amg ® Line Package,Macchiato Beige/Grey; Nappa Leather Upholstery,Wheels: 20" Amg ® Multispoke,Panoramic Roof,Leather Seats,Navigation System,...

    Features and Specs:

    Listing Information:

    VIN: W1K6G7GB6TA347746
    Stock: TA347746

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Houston North (345 mi away)3.62 out of 5 stars(13)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Houston, TX / 345 miles away from Picayune, MS

    Amg ® Line Package,Wheels: 20" Amg ® Multi Spoke,Panoramic Roof,Animated Led Logo Projector,Rear Deck Spoiler In Body Color,Leather Seats,Navi...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB1SA333137
    Stock: SA333137
    Listed since: 05-27-2025

  • Arriving Soon
    • Mercedes-Benz of Houston Greenway (349 mi away)4.77 out of 5 stars(48)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 349 miles away from Picayune, MS

    Amg ® Line Package,Black; Nappa Leather Upholstery,Panoramic Roof,Leather Seats,Navigation System,Lane Keeping Assist,Keyless Start,Cooled Front S...

    Features and Specs:

    Listing Information:

    VIN: W1K6G7GB0TA353557
    Stock: TA353557

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Houston Greenway (349 mi away)4.77 out of 5 stars(48)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Houston, TX / 349 miles away from Picayune, MS

    Wheels: 20" Y-Multispoke,Panoramic Roof,Rear Deck Spoiler In Body Color,Leather Seats,Navigation System,Comfort Box,All-Season Front & Rear Floormats;...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB6SA330251
    Stock: SA330251
    Listed since: 06-02-2025

    • Mercedes-Benz of Houston Greenway (349 mi away)4.77 out of 5 stars(48)
    • Leather Seats
    • Panoramic Roof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    Close

    Located in Houston, TX / 349 miles away from Picayune, MS

    Macchiato Beige/Black; Exclusive Nappa Leather Upholstery,3D Technology Package,Digital Light Led Headlamps W/Projection Function,10-Degree Rear Axle ...

    Features and Specs:

    Listing Information:

    VIN: W1K6G6KB5TA348436
    Stock: TA348436
    Listed since: 08-26-2025

Showing 1 - 21 out of 787 listings
TrimMPGEngineStarting Price
2025 Mercedes-Benz S-Class S 580 4MATIC 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric mild hybrid 9A)17 - 258-cylinders (mild hybrid)$132,090
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)N/A8-cylinders (plug-in hybrid)$210,405
2026 Mercedes-Benz S-Class undefinedN/AN/A$136,800

More about the Mercedes-Benz S-Class

Edmunds has 787 New Mercedes-Benz S-Classes for sale near you, including a 2025 S-Class S 580 4MATIC Sedan and a 2025 S-Class AMG S 63 E PERFORMANCE Sedan ranging in price from $132,090 to $210,405.

How much is a new 2026 Mercedes-Benz S-Class in Picayune, MS?

A new 2026 Mercedes-Benz S-Class starts at $132,090 (including destination charge) in Picayune, MS. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2026 Mercedes-Benz S-Class Sedan cost in Picayune, MS?

A new 2026 Mercedes-Benz S-Class Sedan starts at $132,090 in Picayune, MS. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2026 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE which starts at $210,405.
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