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    • Exterior color: MANUFAKTUR Olive MetallicMANUFAKTUR Olive Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • Mercedes-Benz of Gainesville (204 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Gainesville, FL / 204 miles away from Panama City, FL

    Manufaktur Sign 2024 Mercedes-Benz S-Class S 580e 4MATIC® 4MATIC® 9-Speed Automatic I6CALL OR EMAIL TODAY TO CHECK AVAILABILITY AND ADDITIONAL OPTIO...

    Features and Specs:

    Listing Information:

    VIN: W1K6G6KB5RA303120
    Stock: A303120
    Listed since: 08-07-2024

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Gainesville (204 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Gainesville, FL / 204 miles away from Panama City, FL

    White 2025 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8CALL OR EMAIL TODAY TO CHECK AVAILABILITY AND ADDITIONAL OPTIONS.

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA342509
    Stock: A342509
    Listed since: 07-17-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Gainesville (204 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Gainesville, FL / 204 miles away from Panama City, FL

    White 2025 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8CALL OR EMAIL TODAY TO CHECK AVAILABILITY AND ADDITIONAL OPTIONS.

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB4SA340390
    Stock: A340390
    Listed since: 07-10-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Gainesville (204 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Gainesville, FL / 204 miles away from Panama City, FL

    Manufaktur Moon 2024 Mercedes-Benz S-Class S 63 E AMG® 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8CALL OR EMAIL TODAY TO CHECK AVAILABILITY AND ADDITI...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB9RA301977
    Stock: A301977
    Listed since: 12-04-2024

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Birmingham (238 mi away)5 out of 5 stars(12)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Irondale, AL / 238 miles away from Panama City, FL

    4.0L V8, 4MATIC®, Macchiato Beige/Grey Leather. Want us to come to you? No problem! In case we missed a picture or a detail you would like to see of t...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA333129
    Stock: M333129
    Listed since: 05-24-2025

  • New Listing
    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Birmingham (238 mi away)5 out of 5 stars(12)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Irondale, AL / 238 miles away from Panama City, FL

    4.0L V8, 4MATIC®, Sienna Brown/Black Leather. Want us to come to you? No problem! In case we missed a picture or a detail you would like to see of thi...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA337062
    Stock: M337062
    Listed since: 08-01-2025

    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Carmine Red/Black premium leatherCarmine Red/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Birmingham (238 mi away)5 out of 5 stars(12)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Irondale, AL / 238 miles away from Panama City, FL

    4.0L V8, 4MATIC®, Carmine Red/Black Leather. Want us to come to you? No problem! In case we missed a picture or a detail you would like to see of this...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA319862
    Stock: M319862
    Listed since: 11-20-2024

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Birmingham (238 mi away)5 out of 5 stars(12)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Irondale, AL / 238 miles away from Panama City, FL

    4.0L V8, 4MATIC®, Black Leather. Want us to come to you? No problem! In case we missed a picture or a detail you would like to see of this 2025 S-Clas...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA324740
    Stock: M324740
    Listed since: 07-18-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Wesley Chapel (242 mi away)4.13 out of 5 stars(16)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wesley Chapel, FL / 242 miles away from Panama City, FL

    Amg ® Line Package,Manufaktur Moonlight White Metallic,Stainless Steel Blended Black/Silver Trim,Wheels: 20" Amg ® Multispoke,Panoramic Roof,A...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GBXSA334156
    Stock: SA334156
    Listed since: 05-29-2025

    • Exterior color: BlackBlack
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Wesley Chapel (242 mi away)4.13 out of 5 stars(16)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wesley Chapel, FL / 242 miles away from Panama City, FL

    Amg ® Line Package,Wheels: 20" Amg ® Multi Spoke,Panoramic Roof,Rear Deck Spoiler In Body Color,Leather Seats,Navigation System,Night Package,...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB8SA335015
    Stock: SA335015
    Listed since: 05-30-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    Obsidian Black Metallic 2025 Mercedes-Benz Sedan S-Class S 580 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Black Leather.*har...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB9SA325366
    Stock: CMT252159
    Listed since: 04-23-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    Obsidian Black Metallic 2025 Mercedes-Benz Sedan S-Class S 580 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Black Leather.*har...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB9SA340613
    Stock: CMT252764
    Listed since: 06-29-2025

    • Exterior color: BlackBlack
    • Interior color: Carmine Red/Black premium leatherCarmine Red/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    Black 2025 Mercedes-Benz Sedan S-Class S 580 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Carmine Red/Black Leather.*harman/ka...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GBXSA342760
    Stock: CMT252766
    Listed since: 06-27-2025

    • Exterior color: BlackBlack
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    Black 2025 Mercedes-Benz Sedan S-Class S 580 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Sienna Brown/Black Leather.*harman/k...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA335988
    Stock: CMT252261
    Listed since: 05-07-2025

    • Exterior color: MANUFAKTUR Graphite Grey MagnoMANUFAKTUR Graphite Grey Magno
    • Interior color: Black premium leatherBlack premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    MANUFAKTUR Graphite Grey Magno 2025 Mercedes-Benz Sedan S-Class S 63 E AMG®® 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Blac...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB2SA329531
    Stock: CMT252324
    Listed since: 05-14-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    Black 2025 Mercedes-Benz Sedan S-Class S 580 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Black Leather.*harman/kardon and Log...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB7SA337208
    Stock: CMT252736
    Listed since: 06-26-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    Black 2025 Mercedes-Benz Sedan S-Class S 580 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Black Leather.*harman/kardon and Log...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GBXSA338305
    Stock: CMT252719
    Listed since: 06-20-2025

    • Exterior color: Graphite Grey MetallicGraphite Grey Metallic
    • Interior color: Carmine Red/Black premium leatherCarmine Red/Black premium leather
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    Graphite Grey Metallic 2025 Mercedes-Benz Sedan S-Class S 63 E AMG®® 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Carmine Red/...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB7SA333123
    Stock: CMT252037
    Listed since: 04-10-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    Obsidian Black Metallic 2025 Mercedes-Benz Sedan S-Class S 580 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Macchiato Beige/Gr...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA339930
    Stock: CMT252631
    Listed since: 06-18-2025

    • Exterior color: Graphite Grey MetallicGraphite Grey Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 48 mi est. electric range
    • 20 City / 29 Hwy MPG
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    Graphite Grey Metallic 2025 Mercedes-Benz Sedan S-Class S 580e 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic I6 I6, 4MATIC®, Macchiato Beige/Grey Leather...

    Features and Specs:

    23 Combined MPG (20 City/29 Highway)

    Listing Information:

    VIN: W1K6G6KB1SA336685
    Stock: CMT252384
    Listed since: 05-23-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • Mercedes-Benz of Tampa (245 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Tampa, FL / 245 miles away from Panama City, FL

    MANUFAKTUR Moonlight White Metallic 2025 Mercedes-Benz Sedan S-Class S 63 E AMG®® 4D Sedan 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®,...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CBXSA334055
    Stock: CMT252187
    Listed since: 04-27-2025

Showing 1 - 21 out of 642 listings
TrimMPGEngineStarting Price
2024 Mercedes-Benz S-Class S 580e 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)N/A6-cylinders (plug-in hybrid)$152,375
2025 Mercedes-Benz S-Class S 580 4MATIC 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric mild hybrid 9A)17 - 258-cylinders (mild hybrid)$136,890
2024 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)N/A8-cylinders (plug-in hybrid)$213,210
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)15 - 238-cylinders (plug-in hybrid)$201,360
2025 Mercedes-Benz S-Class S 580e 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)20 - 296-cylinders (plug-in hybrid)$138,195

More about the Mercedes-Benz S-Class

Edmunds has 642 New Mercedes-Benz S-Classes for sale near you, including a 2025 S-Class S 580 4MATIC Sedan and a 2024 S-Class AMG S 63 E PERFORMANCE Sedan ranging in price from $136,890 to $213,210.

How much is a new 2025 Mercedes-Benz S-Class in Panama City, FL?

A new 2025 Mercedes-Benz S-Class starts at $136,890 (including destination charge) in Panama City, FL. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Mercedes-Benz S-Class Sedan cost in Panama City, FL?

A new 2025 Mercedes-Benz S-Class Sedan starts at $136,890 in Panama City, FL. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE which starts at $202,660.
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