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    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Austin (669 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Austin, TX / 669 miles away from Columbia, MO

    Moonlight White 2025 Mercedes-Benz S-Class S 580 4MATIC®This vehicle comes with the following features and options : AMG® Line Package (AMG® Floor Mat...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB9SA340479
    Stock: M67773
    Listed since: 06-13-2025

    • Exterior color: MANUFAKTUR Graphite Grey MagnoMANUFAKTUR Graphite Grey Magno
    • Interior color: Black premium leatherBlack premium leather
    • 48 mi est. electric range
    • 20 City / 29 Hwy MPG
    • Mercedes-Benz of Austin (669 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Austin, TX / 669 miles away from Columbia, MO

    MANUFAKTUR Graphite Gray Magno 2025 Mercedes-Benz S-Class S 580e 4MATIC®This vehicle comes with the following features and options : AMG® Line Package...

    Features and Specs:

    23 Combined MPG (20 City/29 Highway)

    Listing Information:

    VIN: W1K6G6KB7SA342720
    Stock: M67794
    Listed since: 07-07-2025

    • Exterior color: BlackBlack
    • Interior color: Silver Grey/Black premium leatherSilver Grey/Black premium leather
    • Mercedes-Benz Of Denver (680 mi away)4.7 out of 5 stars(57)
    • Five Star Dealer
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Denver, CO / 680 miles away from Columbia, MO

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB6SA328687
    Stock: SA328687
    Listed since: 03-29-2025

    • Exterior color: MANUFAKTUR Olive MetallicMANUFAKTUR Olive Metallic
    • Interior color: MANUFAKTUR Signature Truffle Brown/Black premium leatherMANUFAKTUR Signature Truffle Brown/Black premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz Of Denver (680 mi away)4.7 out of 5 stars(57)
    • Five Star Dealer
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Denver, CO / 680 miles away from Columbia, MO

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB5SA332584
    Stock: SA332584
    Listed since: 05-16-2025

    • Exterior color: MANUFAKTUR Graphite GreyMANUFAKTUR Graphite Grey
    • Interior color: Silver Grey/Black premium leatherSilver Grey/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz Of Denver (680 mi away)4.7 out of 5 stars(57)
    • Five Star Dealer
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Denver, CO / 680 miles away from Columbia, MO

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB6SA326376
    Stock: SA326376
    Listed since: 02-18-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz Of Denver (680 mi away)4.7 out of 5 stars(57)
    • Five Star Dealer
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Denver, CO / 680 miles away from Columbia, MO

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB8RA282208
    Stock: RA282208
    Listed since: 12-20-2024

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Westminster (687 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Westminster, CO / 687 miles away from Columbia, MO

    White 2025 Mercedes-Benz S-Class S 63 E AMG® 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Black Leather. Proudly serving Colorado since...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB0SA329382
    Stock: SA329382
    Listed since: 04-10-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Selma (731 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Selma, TX / 731 miles away from Columbia, MO

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB3SA327095
    Stock: T250388
    Listed since: 06-11-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Selma (731 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Selma, TX / 731 miles away from Columbia, MO

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB1SA339620
    Stock: T250547
    Listed since: 06-13-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Selma (731 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Selma, TX / 731 miles away from Columbia, MO

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB4SA312780
    Stock: T250133
    Listed since: 11-04-2024

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 21 City / 31 Hwy MPG
    • Mercedes-Benz of San Antonio (740 mi away)4.8 out of 5 stars(25)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Antonio, TX / 740 miles away from Columbia, MO

    Black 2025 Mercedes-Benz S-Class S 500 4MATIC®4MATIC® 9-Speed Automatic 3.0L I6 Turbo 4MATIC®, Black Leather, 15 Speakers, 3-Spoke Wood & Leather Stee...

    Features and Specs:

    24 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: W1K6G6DB9SA330744
    Stock: 330744
    Listed since: 04-10-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of San Antonio (740 mi away)4.8 out of 5 stars(25)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Antonio, TX / 740 miles away from Columbia, MO

    Black 2025 Mercedes-Benz S-Class S 63 E AMG® 4MATIC®4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Black Leather, 15 Speakers, 4-Wheel Disc Brake...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB1SA333053
    Stock: 333053
    Listed since: 04-15-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of San Antonio (740 mi away)4.8 out of 5 stars(25)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Antonio, TX / 740 miles away from Columbia, MO

    Black 2025 Mercedes-Benz S-Class S 63 E AMG® 4MATIC®4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Black Leather, 15 Speakers, 4-Wheel Disc Brake...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB7SA320534
    Stock: 320534
    Listed since: 11-15-2024

    • Exterior color: Onyx Black MetallicOnyx Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of San Antonio (740 mi away)4.8 out of 5 stars(25)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Antonio, TX / 740 miles away from Columbia, MO

    WARMTH COMFORT PACKAGE, AMG LINE PACKAGE, AMG LINE, 3D DRIVER'S DISPLAY, ACTIVE LANE CHANGE ASSIST, 20" AMG MULTISPOKE WHEELS.Onyx Black Metallic 2024...

    Features and Specs:

    Listing Information:

    VIN: W1K6G6KB4RA276105
    Stock: 276105
    Listed since: 01-25-2024

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of San Antonio (740 mi away)4.8 out of 5 stars(25)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in San Antonio, TX / 740 miles away from Columbia, MO

    Obsidian 2025 Mercedes-Benz S-Class S 580e 4MATIC®4MATIC® 9-Speed Automatic I6 I6, 4MATIC®, Black Leather, 15 Speakers, 4-Wheel Disc Brakes, ABS brake...

    Features and Specs:

    Listing Information:

    VIN: W1K6G6KB1SA321457
    Stock: 321457
    Listed since: 11-19-2024

    • Exterior color: MANUFAKTUR Mystic Blue MetallicMANUFAKTUR Mystic Blue Metallic
    • Interior color: MANUFAKTUR Signature Deep White/Black premium leatherMANUFAKTUR Signature Deep White/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Fredericksburg (796 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Fredericksburg, VA / 796 miles away from Columbia, MO

    This 2025 MANUFAKTUR Signature Mystic Blue Metallic Mercedes-Benz S-Class S 580 AWD 4MATIC® is well equipped and includes these features and benefits:...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB4SA323556
    Stock: 15569M
    Listed since: 01-16-2025

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Fredericksburg (796 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Fredericksburg, VA / 796 miles away from Columbia, MO

    This 2025 Black Mercedes-Benz S-Class S 580 AWD 4MATIC® is well equipped and includes these features and benefits:air balance, 4-Zone Climate Contro...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB6SA327768
    Stock: 15632M
    Listed since: 02-28-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Alexandria (813 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Alexandria, VA / 813 miles away from Columbia, MO

    MANUFAKTUR Moonlight White Metallic 2025 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Black w/Nappa Leather...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB8SA324399
    Stock: SA324399
    Listed since: 12-21-2024

    • Exterior color: MANUFAKTUR Graphite Grey MagnoMANUFAKTUR Graphite Grey Magno
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Alexandria (813 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Alexandria, VA / 813 miles away from Columbia, MO

    MANUFAKTUR Graphite Gray Magno 2025 Mercedes-Benz S-Class S 63 E AMG® 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 Carbon Fiber Trim, 4.0L V8, 4MATIC®, C...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB6SA327698
    Stock: SA327698
    Listed since: 04-09-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Arlington (813 mi away)5 out of 5 stars(18)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Arlington, VA / 813 miles away from Columbia, MO

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB4SA325562
    Stock: AA325562
    Listed since: 01-16-2025

    • Exterior color: MANUFAKTUR Graphite MetallicMANUFAKTUR Graphite Metallic
    • Interior color: MANUFAKTUR Signature Truffle Brown/Black premium leatherMANUFAKTUR Signature Truffle Brown/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Arlington (813 mi away)5 out of 5 stars(18)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Arlington, VA / 813 miles away from Columbia, MO

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB1SA337964
    Stock: AA337964
    Listed since: 06-25-2025

Showing 127 - 147 out of 722 listings
TrimMPGEngineStarting Price
2025 Mercedes-Benz S-Class S 580 4MATIC 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric mild hybrid 9A)17 - 258-cylinders (mild hybrid)$131,545
2025 Mercedes-Benz S-Class S 580e 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)20 - 296-cylinders (plug-in hybrid)$136,805
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)N/A8-cylinders (plug-in hybrid)$191,945
2024 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)N/A8-cylinders (plug-in hybrid)$202,810
2025 Mercedes-Benz S-Class S 500 4MATIC 4dr Sedan AWD (3.0L 6cyl Twincharger gas/electric mild hybrid 9A)21 - 316-cylinders (mild hybrid)$128,400
2024 Mercedes-Benz S-Class S 580e 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)N/A6-cylinders (plug-in hybrid)$145,985

More about the Mercedes-Benz S-Class

Edmunds has 722 New Mercedes-Benz S-Classes for sale near you, including a 2025 S-Class S 500 4MATIC Sedan and a 2025 S-Class AMG S 63 E PERFORMANCE Sedan ranging in price from $128,400 to $223,170.

How much is a new 2025 Mercedes-Benz S-Class in Columbia, MO?

A new 2025 Mercedes-Benz S-Class starts at $128,400 (including destination charge) in Columbia, MO. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Mercedes-Benz S-Class Sedan cost in Columbia, MO?

A new 2025 Mercedes-Benz S-Class Sedan starts at $128,400 in Columbia, MO. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE which starts at $195,620.
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