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    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Louisville (367 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Louisville, KY / 367 miles away from Columbia, MO

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA325595
    Stock: 372742
    Listed since: 01-09-2025

    • Exterior color: GrayGray
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Louisville (367 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Louisville, KY / 367 miles away from Columbia, MO

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB7SA329783
    Stock: 372957
    Listed since: 04-01-2025

    • Exterior color: MANUFAKTUR Graphite Grey MagnoMANUFAKTUR Graphite Grey Magno
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Fort Mitchell (413 mi away)5 out of 5 stars(6)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Park Hills, KY / 413 miles away from Columbia, MO

    DB4 Rear Seat Package $4,150 236 Adaptive rear compartment lighting 306 Beltbag 439 EASY ADJUST luxury head restraints for driver and frontpasseng...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB2RA304185
    Stock: 369055
    Listed since: 12-17-2024

    • Interior color: Carmine Red/Black premium leatherCarmine Red/Black premium leather
    • Mercedes-Benz of Fort Mitchell (413 mi away)5 out of 5 stars(6)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Park Hills, KY / 413 miles away from Columbia, MO

    DC1 Night Package $750 5U6 AMG-specific radiator grille, darkened P60 AMG Exterior Night Styling U50 Omission of Dark Tinted Windows US Regulatory...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB5SA320595
    Stock: 369058
    Listed since: 12-18-2024

  • New Listing
    Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 48 mi est. electric range
    • 20 City / 29 Hwy MPG
    • Mercedes-Benz of Fort Mitchell (413 mi away)5 out of 5 stars(6)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Park Hills, KY / 413 miles away from Columbia, MO

    Features and Specs:

    23 Combined MPG (20 City/29 Highway)

    Listing Information:

    VIN: W1K6G6KB8SA319690
    Stock: 369576
    Listed since: 07-17-2025

    • Exterior color: Emerald Green MetallicEmerald Green Metallic
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Fort Mitchell (413 mi away)5 out of 5 stars(6)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Park Hills, KY / 413 miles away from Columbia, MO

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB5SA318818
    Stock: 368941
    Listed since: 12-03-2024

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Fort Mitchell (413 mi away)5 out of 5 stars(6)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Park Hills, KY / 413 miles away from Columbia, MO

    OptionsDC1 Night Package $750 5U6 AMG-specific radiator grille, darkened P60 AMG Exterior Night Styling U50 Omission of Dark Tinted Windows US Re...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB7SA332635
    Stock: 369355
    Listed since: 04-02-2025

    • Interior color: Black premium leatherBlack premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Fort Mitchell (413 mi away)5 out of 5 stars(6)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Park Hills, KY / 413 miles away from Columbia, MO

    DB4 Rear Seat Package $4,150 236 Adaptive rear compartment lighting 306 Beltbag 439 EASY ADJUST luxury head restraints for driver and frontpasseng...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB7SA332165
    Stock: 369494
    Listed since: 06-02-2025

    • Interior color: Silver Grey/Black premium leatherSilver Grey/Black premium leather
    • Mercedes-Benz of Fort Mitchell (413 mi away)5 out of 5 stars(6)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Park Hills, KY / 413 miles away from Columbia, MO

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB2SA327942
    Stock: 369347
    Listed since: 04-02-2025

    • Exterior color: GrayGray
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Fort Mitchell (413 mi away)5 out of 5 stars(6)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Park Hills, KY / 413 miles away from Columbia, MO

    DB0 Warmth Comfort Package $3,500 223 Power Rear Seats 276 Rear Seat with Memory 402 Heated & Ventilated Rear Seats 903 Rapid Heating Rear Seats ...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB1SA324132
    Stock: 369083
    Listed since: 12-26-2024

  • Stock photo**
    • Exterior color: BlackBlack
    • Interior color: MANUFAKTUR Signature Nut Brown/Black premium leatherMANUFAKTUR Signature Nut Brown/Black premium leather
    • Mercedes-Benz of Huntsville (421 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 421 miles away from Columbia, MO

    Black 2025 Mercedes-Benz S-Class S 63 E AMG® 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®, MANUFAK...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB8SA321367
    Stock: S0199
    Listed since: 12-02-2024

    • Exterior color: BlackBlack
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Huntsville (421 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 421 miles away from Columbia, MO

    Black 2025 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®, Black w/Nappa...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB8SA337301
    Stock: S0444
    Listed since: 05-15-2025

    • Exterior color: MANUFAKTUR Graphite Grey MagnoMANUFAKTUR Graphite Grey Magno
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Huntsville (421 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 421 miles away from Columbia, MO

    Graphite Grey 2025 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®, Black...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB3SA318624
    Stock: S0198
    Listed since: 11-26-2024

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Huntsville (421 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 421 miles away from Columbia, MO

    Obsidian Black 2025 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®, Leat...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB7SA339217
    Stock: S0474
    Listed since: 06-12-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Huntsville (421 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 421 miles away from Columbia, MO

    Moonlight White 2025 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®, Mac...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA333499
    Stock: S0415
    Listed since: 05-05-2025

  • Stock photo**
    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Centerville (436 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Centerville, OH / 436 miles away from Columbia, MO

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB1SA336104
    Stock: M6410
    Listed since: 05-29-2025

  • Stock photo**
    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Carmine Red/Black premium leatherCarmine Red/Black premium leather
    • Mercedes-Benz of Centerville (436 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Centerville, OH / 436 miles away from Columbia, MO

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB6SA333856
    Stock: M6380
    Listed since: 04-25-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Plano (478 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Plano, TX / 478 miles away from Columbia, MO

    2025 Mercedes-Benz S-Class 4D Sedan MANUFAKTUR Moonlight White Metallic S 580 4MATIC® 4.0L V8 9-Speed Automatic 4MATIC®4.0L V8, 4MATIC®, Macchiato ...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB4SA328191
    Stock: MSA328191
    Listed since: 04-01-2025

    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Plano (478 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Plano, TX / 478 miles away from Columbia, MO

    2025 Mercedes-Benz S-Class 4D Sedan Cirrus Silver Metallic S 580 4MATIC® 4.0L V8 9-Speed Automatic 4MATIC®4.0L V8, 4MATIC®, Black w/Nappa Leather U...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB2SA342087
    Stock: MSA342087
    Listed since: 06-30-2025

    • Exterior color: BlackBlack
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • Mercedes-Benz of Plano (478 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Plano, TX / 478 miles away from Columbia, MO

    2025 Mercedes-Benz S-Class 4D Sedan Black S 580e 4MATIC® I6 9-Speed Automatic 4MATIC®I6, 4MATIC®, Macchiato Beige/Magma Gray w/Nappa Leather Uphols...

    Features and Specs:

    Listing Information:

    VIN: W1K6G6KB1SA333110
    Stock: MSA333110
    Listed since: 04-18-2025

    • Interior color: Black premium leatherBlack premium leather
    • Mercedes-Benz of Plano (478 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Plano, TX / 478 miles away from Columbia, MO

    2025 Mercedes-Benz S-Class 4D Sedan Graphite Gray Metallic S 63 E AMG® 4MATIC® 4.0L V8 9-Speed Automatic 4MATIC®4.0L V8, 4MATIC®, Black w/AMG Nappa...

    Features and Specs:

    Listing Information:

    VIN: W1K6G8CB3SA318666
    Stock: MSA318666
    Listed since: 11-07-2024

Showing 22 - 42 out of 728 listings
TrimMPGEngineStarting Price
2025 Mercedes-Benz S-Class S 580 4MATIC 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric mild hybrid 9A)17 - 258-cylinders (mild hybrid)$132,065
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)N/A8-cylinders (plug-in hybrid)$198,900
2024 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)N/A8-cylinders (plug-in hybrid)$200,455
2025 Mercedes-Benz S-Class S 580e 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)20 - 296-cylinders (plug-in hybrid)$130,095

More about the Mercedes-Benz S-Class

Edmunds has 728 New Mercedes-Benz S-Classes for sale near you, including a 2025 S-Class S 580e 4MATIC Sedan and a 2025 S-Class AMG S 63 E PERFORMANCE Sedan ranging in price from $130,095 to $239,765.

How much is a new 2025 Mercedes-Benz S-Class in Columbia, MO?

A new 2025 Mercedes-Benz S-Class starts at $130,095 (including destination charge) in Columbia, MO. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Mercedes-Benz S-Class Sedan cost in Columbia, MO?

A new 2025 Mercedes-Benz S-Class Sedan starts at $132,065 in Columbia, MO. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE which starts at $198,900.
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