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  • Stock photo**
    • Exterior color: BlackBlack
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (485 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Jacksonville, FL / 485 miles away from Picayune, MS

    This Mercedes-Benz E 350 RWD Sedan has a dependable Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window G...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GBXSA128324
    Stock: BSA128324
    Listed since: 01-15-2025

  • Arriving Soon
    • Exterior color: BlackBlack
    • Interior color: Macchiato Beige/Black leatheretteMacchiato Beige/Black leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (485 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Jacksonville, FL / 485 miles away from Picayune, MS

    This Mercedes-Benz E 350 4MATIC Sedan has a powerful Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window ...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB5SA102079
    Stock: PBL9340
    Listed since: 09-11-2024

  • Stock photo**
    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (485 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Jacksonville, FL / 485 miles away from Picayune, MS

    This Mercedes-Benz E 350 4MATIC Sedan has a powerful Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window ...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB3SA170428
    Stock: BSA170428
    Listed since: 08-20-2025

  • Photos not available
    • Mercedes-Benz of Jacksonville (485 mi away)
    • All Wheel Drive
    • Heated Front Seat(s)
    • Dual Moonroof
    • Back-Up Camera
    • Blind Spot Monitor
    Close

    Located in Jacksonville, FL / 485 miles away from Picayune, MS

    This Mercedes-Benz E 350 4MATIC Sedan has a dependable Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Wirel...

    Features and Specs:

    Listing Information:

    VIN: W1KLF4HB6TA212026
    Stock: BTA212026
    Listed since: 08-29-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 22 City / 31 Hwy MPG
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Pinnacle Trim,Multicontour Seating Package,Driver Assistance Package,Mbux Superscreen Package,Wheels: 19" Amg ® 5-Twin-Spoke Light-Alloy W/Black,D...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLF6BB2SA169131
    Stock: SA169131
    Listed since: 05-31-2025

    • Exterior color: Graphite Grey MetallicGraphite Grey Metallic
    • Interior color: Tonka Brown/Black leatheretteTonka Brown/Black leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Driver Assistance Package,Wheels: 19" Amg ® 5-Twin-Spoke Light-Alloy W/Black,Burmester ® 4D Surround Sound,Digital Light Package,Graphite Grey...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GBXSA137587
    Stock: SA137587
    Listed since: 06-30-2025

  • Arriving Soon
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Dual Moonroof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    • Lane Keeping Assist
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Driver Assistance Package,Mbux Superscreen Package,Dual Moonroof,Navigation System,Ventilated Front Seats,Center Console In Natural Grain Maple Wood,L...

    Features and Specs:

    Listing Information:

    VIN: W1KLF4GB8TA212496
    Stock: TA212496

  • New Listing
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Dual Moonroof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    • Lane Keeping Assist
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Driver Assistance Package,Wheels: 20" Amg ® Multi-Spoke Alloy,Mbux Superscreen Package,Burmester ® 4D Surround Sound,Nautical Blue Metallic,Du...

    Features and Specs:

    Listing Information:

    VIN: W1KLF4GB8TA207833
    Stock: TA207833
    Listed since: 09-09-2025

  • New Listing
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Dual Moonroof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    • Lane Keeping Assist
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Driver Assistance Package,Wheels: 20" Amg ® Multi-Spoke Alloy,Mbux Superscreen Package,Burmester ® 4D Surround Sound,Sonoran Brown Metallic,Du...

    Features and Specs:

    Listing Information:

    VIN: W1KLF4GB1TA208340
    Stock: TA208340
    Listed since: 09-09-2025

  • New Listing
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Leather Package -Inc...
    • Dual Moonroof
    • Keyless Start
    • Navigation System
    • Winter Package -Inc:...
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Pinnacle Trim,Multicontour Seating Package,Driver Assistance Package,Wheels: 20" Amg ® Multi-Spoke Alloy,Macchiato Beige/Black; Leather Upholstery...

    Features and Specs:

    Listing Information:

    VIN: W1KLF6BB8TA204286
    Stock: TA204286
    Listed since: 09-08-2025

    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Dual Moonroof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    • Lane Keeping Assist
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Wheels: 21" Amg ® Multi-Spoke Light-Alloy W/Black,Driver Assistance Package,Mbux Superscreen Package,Graphite Grey Metallic,Dual Moonroof,Navigati...

    Features and Specs:

    Listing Information:

    VIN: W1KLF4GB1TA205082
    Stock: TA205082
    Listed since: 08-28-2025

    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Dual Moonroof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    • Lane Keeping Assist
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Driver Assistance Package,Wheels: 20" Amg ® Multi-Spoke Alloy,Mbux Superscreen Package,Burmester ® 4D Surround Sound,Nautical Blue Metallic,Du...

    Features and Specs:

    Listing Information:

    VIN: W1KLF4GB2TA201655
    Stock: TA201655
    Listed since: 08-26-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Tonka Brown/Black leatheretteTonka Brown/Black leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Driver Assistance Package,Manufaktur Moonlight White Metallic,Natural Grain Brown Maple Wood Trim W/Alum Lines,Burmester ® 4D Surround Sound,Dual ...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB6SA157092
    Stock: SA157092
    Listed since: 06-30-2025

    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Dual Moonroof,Wheels: 19" Multi-Spoke Light-Alloy,Navigation System,Winter Package,Wheel Locking Bolts,Keyless Start,First Aid Kit,Black,Black; Mb-Tex...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB4SA161771
    Stock: SA161771
    Listed since: 05-31-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Multicontour Seating Package,Driver Assistance Package,Mbux Superscreen Package,Digital Light Package,Panoramic Roof,Navigation System,Winter Package,...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB9SA153013
    Stock: SA153013
    Listed since: 07-23-2025

    • Exterior color: BlackBlack
    • Interior color: Macchiato Beige/Black leatheretteMacchiato Beige/Black leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Driver Assistance Package,Wheels: 20" Amg ® Multi-Spoke Alloy,Burmester ® 4D Surround Sound,Dual Moonroof,Navigation System,Ventilated Front S...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB0SA170419
    Stock: SA170419
    Listed since: 08-31-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Dual Moonroof,Wheels: 19" 5-Spoke Light-Alloy (R82),Navigation System,Wheel Locking Bolts,Natural Grain Black Ash Wood Trim W/Star Pattern,Keyless Sta...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB2SA160684
    Stock: SA160684
    Listed since: 08-19-2025

    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Driver Assistance Package,Wheels: 19" Amg ® 5-Twin-Spoke Light-Alloy W/Black,Burmester ® 4D Surround Sound,Dual Moonroof,Navigation System,Ven...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB7SA135570
    Stock: SA135570
    Listed since: 07-14-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 22 City / 31 Hwy MPG
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Pinnacle Trim,Multicontour Seating Package,Driver Assistance Package,Mbux Superscreen Package,Wheels: 19" Amg ® 5-Twin-Spoke Light-Alloy W/Black,D...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLF6BB7SA171084
    Stock: SA171084
    Listed since: 06-04-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black leatherBlack leather
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Black; Leather Upholstery,Leather Package,Panoramic Roof,Leather Seats,Navigation System,Winter Package,Wheel Locking Bolts,Keyless Start,Rear Spoiler...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB4SA164095
    Stock: SA164095
    Listed since: 07-23-2025

    • Mercedes-Benz of Sarasota (492 mi away)4.89 out of 5 stars(28)
    • Dual Moonroof
    • Keyless Start
    • Navigation System
    • Cooled Front Seat(S)
    • Lane Keeping Assist
    Close

    Located in Sarasota, FL / 492 miles away from Picayune, MS

    Driver Assistance Package,Manufaktur Patagonia Red,Mbux Superscreen Package,Dual Moonroof,Wheels: 19" 5-Spoke Light-Alloy (R82),Navigation System,Vent...

    Features and Specs:

    Listing Information:

    VIN: W1KLF4GB3TA211871
    Stock: TA211871
    Listed since: 08-28-2025

Showing 190 - 210 out of 1,178 listings

Consumer Reviews for the Mercedes-Benz E-Class

Read recent reviews for the Mercedes-Benz E-Class
Overall Consumer Rating
4.3 out of 5 stars9 Reviews
Write a vehicle reviewSee all 9 reviews
  • 5 star
    (67%)
  • 4 star
    (11%)
  • 3 star
    (11%)
  • 2 star
    (11%)
  • 1 star
    (0%)
5 out of 5 stars

Fantastic car!

Leon from Westchester NY, 07/30/2024
2024 Mercedes-Benz E-Class E 450 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A)
The 2024 E450 is a powerhouse. When in sports drive you literally can get pinned to your seat during a fast acceleration. The car is super quiet and extremely smooth on the highway even at 70MPH. The interior is luxurious and comfortable. The driver assist is remarkable enabling you to fully relax at highway speeds, even moving to the left automatically when a slower car is front and … returning you to the right lane when done passing. There are so many new technical features that it will take a while to rad/learn them all but I’m planning to schedule another review with the dealer. Both my wife and I love this car and would highly recommend it to others.
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TrimMPGEngineStarting Price
2025 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo gas/electric mild hybrid 9A)25 - 334-cylinders (mild hybrid)$64,545
2025 Mercedes-Benz E-Class E 350 4MATIC 4dr Sedan AWD (2.0L 4cyl Turbo gas/electric mild hybrid 9A)24 - 334-cylinders (mild hybrid)$67,345
2026 Mercedes-Benz E-Class undefinedN/AN/A$72,585
2025 Mercedes-Benz E-Class E 450 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A)22 - 316-cylinders (mild hybrid)$85,995
2025 Mercedes-Benz E-Class E 450 4MATIC All-Terrain 4dr Wagon AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A)22 - 316-cylinders (mild hybrid)$80,345

More about the Mercedes-Benz E-Class

Edmunds has 1,178 New Mercedes-Benz E-Classes for sale near you, including a 2025 E-Class E 350 Sedan and a 2026 E-Class E 450 ranging in price from $64,545 to $91,765.

How much is a new 2026 Mercedes-Benz E-Class in Picayune, MS?

A new 2026 Mercedes-Benz E-Class starts at $64,545 (including destination charge) in Picayune, MS. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2026 Mercedes-Benz E-Class Sedan cost in Picayune, MS?

A new 2026 Mercedes-Benz E-Class Sedan starts at $64,545 in Picayune, MS. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2026 Mercedes-Benz E-Class Wagon which starts at $80,345.
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