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    • Exterior color: Sonoran Brown MetallicSonoran Brown Metallic
    • Interior color: Tonka Brown/Black leatheretteTonka Brown/Black leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Marietta (224 mi away)4.25 out of 5 stars(8)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Marietta, GA / 224 miles away from Lancaster, SC

    Pinnacle Trim,Driver Assistance Package,Wheels: 20" Amg ® Multi-Spoke Alloy,Digital Light Package,Sonoran Brown Metallic,Dual Moonroof,Navigation ...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB0SA159632
    Stock: SA159632
    Listed since: 04-02-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • Mercedes-Benz of Marietta (224 mi away)4.25 out of 5 stars(8)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Marietta, GA / 224 miles away from Lancaster, SC

    Dual Moonroof,Wheels: 19" 5-Spoke Light-Alloy (R82),Navigation System,Winter Package,All-Season Floor Mats (4-Piece),Wheel Locking Bolts,Natural Grain...

    Features and Specs:

    Listing Information:

    VIN: W1KLF4GB5SA109308
    Stock: SA109308
    Listed since: 03-04-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Fredericksburg (304 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Fredericksburg, VA / 304 miles away from Lancaster, SC

    This 2024 Polar White Mercedes-Benz E 350 AWD 4MATIC® is well equipped and includes these features and benefits:Navigation, Backup Camera, Panorama ...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB6RA068163
    Stock: 15200M
    Listed since: 06-26-2024

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    • Exterior color: Graphite Grey MetallicGraphite Grey Metallic
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Fredericksburg (304 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fredericksburg, VA / 304 miles away from Lancaster, SC

    This 2025 Graphite Mercedes-Benz E 350 AWD 4MATIC® is well equipped and includes these features and benefits:24/33 City/Highway MPG

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB0SA173190
    Stock: 15769M
    Listed since: 05-13-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Fredericksburg (304 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fredericksburg, VA / 304 miles away from Lancaster, SC

    This 2025 Obsidian Mercedes-Benz E 350 AWD 4MATIC® is well equipped and includes these features and benefits:24/33 City/Highway MPG

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB2SA159081
    Stock: 15697M
    Listed since: 04-03-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black leatheretteBlack leatherette
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz of Fredericksburg (304 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fredericksburg, VA / 304 miles away from Lancaster, SC

    This 2025 Obsidian Mercedes-Benz E-Class E 450 AWD 4MATIC® is well equipped and includes these features and benefits:22/31 City/Highway MPG

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB5SA150996
    Stock: 15820M
    Listed since: 06-02-2025

    • Exterior color: Nautical Blue MetallicNautical Blue Metallic
    • Interior color: Black w/Red Stitching leatherette/sueded microfiberBlack w/Red Stitching leatherette/sueded microfiber
    • 43 mi est. electric range
    • 21 City / 26 Hwy MPG
    • Mercedes-Benz of Fredericksburg (304 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fredericksburg, VA / 304 miles away from Lancaster, SC

    This 2025 Blue Mercedes-Benz E-Class E 53 AMG® AWD 4MATIC® is well equipped and includes these features and benefits:21/26 City/Highway MPG

    Features and Specs:

    23 Combined MPG (21 City/26 Highway)

    Listing Information:

    VIN: W1KLF6DB2SA172933
    Stock: 15770M
    Listed since: 05-13-2025

    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Fredericksburg (304 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Fredericksburg, VA / 304 miles away from Lancaster, SC

    This 2025 Silver Metallic Mercedes-Benz E 350 AWD 4MATIC® is well equipped and includes these features and benefits:24/33 City/Highway MPG

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB0SA091749
    Stock: 15758M
    Listed since: 05-05-2025

  • Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (309 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Jacksonville, FL / 309 miles away from Lancaster, SC

    This Mercedes-Benz E 350 RWD Sedan has a powerful Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window Gri...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB3SA159446
    Stock: BSA159446
    Listed since: 04-16-2025

    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Black leatherBlack leather
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (309 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 309 miles away from Lancaster, SC

    This Mercedes-Benz E 350 4MATIC Sedan has a strong Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window Gr...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB4RA011380
    Stock: PBL8995
    Listed since: 03-04-2024

    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Black leatherBlack leather
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (309 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 309 miles away from Lancaster, SC

    This Mercedes-Benz E-Class has a dependable Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window Grid Ante...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HBXRA012288
    Stock: PBL9011
    Listed since: 03-18-2024

  • Stock photo**
    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Macchiato Beige/BlackMacchiato Beige/Black
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (309 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Jacksonville, FL / 309 miles away from Lancaster, SC

    This Mercedes-Benz E 350 RWD Sedan has a strong Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window Grid ...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB1SA158148
    Stock: BSA158148
    Listed since: 04-16-2025

  • Stock photo**
    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Macchiato Beige/BlackMacchiato Beige/Black
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (309 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Jacksonville, FL / 309 miles away from Lancaster, SC

    This Mercedes-Benz E 350 RWD Sedan has a strong Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window Grid ...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB7SA158896
    Stock: BSA158896
    Listed since: 04-16-2025

    • Exterior color: BlackBlack
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (309 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Jacksonville, FL / 309 miles away from Lancaster, SC

    This Mercedes-Benz E 350 RWD Sedan has a powerful Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window Gri...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB7SA129995
    Stock: BSA129995
    Listed since: 01-30-2025

  • Stock photo**
    • Exterior color: Verde Silver MetallicVerde Silver Metallic
    • Interior color: Macchiato Beige/BlackMacchiato Beige/Black
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (309 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Jacksonville, FL / 309 miles away from Lancaster, SC

    This Mercedes-Benz E 350 RWD Sedan has a dependable Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window G...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB6SA170960
    Stock: BSA170960
    Listed since: 04-30-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Black leatherMacchiato Beige/Black leather
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (309 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 309 miles away from Lancaster, SC

    This Mercedes-Benz E-Class has a dependable Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window Grid Ante...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB0RA010940
    Stock: PBL9007
    Listed since: 03-04-2024

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Black leatherMacchiato Beige/Black leather
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (309 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Jacksonville, FL / 309 miles away from Lancaster, SC

    This Mercedes-Benz E 350 4MATIC Sedan has a powerful Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window ...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB2RA011118
    Stock: PBL9002
    Listed since: 03-04-2024

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Black leatherMacchiato Beige/Black leather
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Jacksonville (309 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Leather Seats
    Close

    Located in Jacksonville, FL / 309 miles away from Lancaster, SC

    This Mercedes-Benz E 350 4MATIC Sedan has a strong Intercooled Turbo Gas/Electric I-4 2.0 L/122 engine powering this Automatic transmission. Window Gr...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB4RA010438
    Stock: PBL9033
    Listed since: 03-04-2024

  • Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Orange Park (318 mi away)5 out of 5 stars(1)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Jacksonville, FL / 318 miles away from Lancaster, SC

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB9SA160147
    Stock: RSA160147
    Listed since: 06-14-2025

  • Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Orange Park (318 mi away)5 out of 5 stars(1)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Jacksonville, FL / 318 miles away from Lancaster, SC

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB8SA159927
    Stock: RSA159927
    Listed since: 06-14-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Tonka Brown/BlackTonka Brown/Black
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Orange Park (318 mi away)5 out of 5 stars(1)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Jacksonville, FL / 318 miles away from Lancaster, SC

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB8SA102531
    Stock: RSA102531
    Listed since: 10-29-2024

Showing 22 - 42 out of 1,306 listings
TrimMPGEngineStarting Price
2025 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo gas/electric mild hybrid 9A)25 - 334-cylinders (mild hybrid)$64,395
2024 Mercedes-Benz E-Class E 350 4MATIC 4dr Sedan AWD (2.0L 4cyl Turbo gas/electric mild hybrid 9A)24 - 334-cylinders (mild hybrid)$74,415
2025 Mercedes-Benz E-Class E 350 4MATIC 4dr Sedan AWD (2.0L 4cyl Turbo gas/electric mild hybrid 9A)24 - 334-cylinders (mild hybrid)$70,460
2025 Mercedes-Benz E-Class E 450 4MATIC All-Terrain 4dr Wagon AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A)22 - 316-cylinders (mild hybrid)$80,345
2025 Mercedes-Benz E-Class AMG E 53 HYBRID 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)21 - 266-cylinders (plug-in hybrid)$104,710

More about the Mercedes-Benz E-Class

Edmunds has 1,306 New Mercedes-Benz E-Classes for sale near you, including a 2025 E-Class E 350 Sedan and a 2025 E-Class AMG E 53 HYBRID Sedan ranging in price from $64,395 to $104,710.

How much is a new 2025 Mercedes-Benz E-Class in Lancaster, SC?

A new 2025 Mercedes-Benz E-Class starts at $64,395 (including destination charge) in Lancaster, SC. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Mercedes-Benz E-Class Sedan cost in Lancaster, SC?

A new 2025 Mercedes-Benz E-Class Sedan starts at $64,395 in Lancaster, SC. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Mercedes-Benz E-Class Wagon which starts at $80,345.
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