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    • Exterior color: Polar WhitePolar White
    • Interior color: Macchiato Beige/BlackMacchiato Beige/Black
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz Of Denver (601 mi away)4.69 out of 5 stars(55)
    • Five Star Dealer
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
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    Located in Denver, CO / 601 miles away from Des Moines, IA

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB9SA142206
    Stock: SA142206
    Listed since: 01-28-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz Of Denver (601 mi away)4.69 out of 5 stars(55)
    • Five Star Dealer
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Denver, CO / 601 miles away from Des Moines, IA

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FBXSA087474
    Stock: SA087474
    Listed since: 09-23-2024

    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Black leatherBlack leather
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz Of Denver (601 mi away)4.69 out of 5 stars(55)
    • Five Star Dealer
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Denver, CO / 601 miles away from Des Moines, IA

    Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB4SA087258
    Stock: SA087258
    Listed since: 09-26-2024

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Westminster (604 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
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    Located in Westminster, CO / 604 miles away from Des Moines, IA

    Polar White 2025 Mercedes-Benz E-Class E 350 4MATIC® 4MATIC® 9-Speed Automatic 2.0L I4 Turbocharged 2.0L I4 Turbocharged, 4MATIC®. Proudly serving Col...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB3SA147506
    Stock: SA147506
    Listed since: 05-08-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black leatheretteBlack leatherette
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz of Westminster (604 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
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    Located in Westminster, CO / 604 miles away from Des Moines, IA

    Obsidian Black Metallic 2025 Mercedes-Benz E-Class E 450 4MATIC® 4MATIC® 9-Speed Automatic 3.0L I6 Turbo 4MATIC®. Proudly serving Colorado since 2003....

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB2SA134433
    Stock: SA134433
    Listed since: 12-17-2024

    • Exterior color: Nautical Blue MetallicNautical Blue Metallic
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Westminster (604 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
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    Located in Westminster, CO / 604 miles away from Des Moines, IA

    Blue 2025 Mercedes-Benz E-Class E 350 4MATIC® 4MATIC® 9-Speed Automatic 2.0L I4 Turbocharged 2.0L I4 Turbocharged, 4MATIC®. Proudly serving Colorado s...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HBXSA172290
    Stock: SA172290
    Listed since: 05-10-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Littleton (606 mi away)4.96 out of 5 stars(22)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
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    Located in Littleton, CO / 606 miles away from Des Moines, IA

    2025 E350W4149 Polar White101 Black MB-TexOptionsDA0 MBUX Superscreen Package $1,500 219 Selfie and video camera 529 MBUX multimedia system 860...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB0SA146717
    Stock: 250664
    Listed since: 04-10-2025

    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Littleton (606 mi away)4.96 out of 5 stars(22)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
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    Located in Littleton, CO / 606 miles away from Des Moines, IA

    2025 E350W4040 Black101 Black MB-TexOptionsDB0 Winter Package $450 443 Heated Steering Wheel 875 Heated Washer System PAV Winter Package055 Mo...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB3SA163401
    Stock: 250767
    Listed since: 04-14-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Macchiato Beige/Black leatherMacchiato Beige/Black leather
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz of Littleton (606 mi away)4.96 out of 5 stars(22)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Littleton, CO / 606 miles away from Des Moines, IA

    2025 E450S4 Wagon149 Polar White105 Macchiato Beige/ Black MB-TexOptionsDA0 MBUX Superscreen Package $1,500 219 Selfie and video camera 529 MBUX...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB4SA162959
    Stock: 250620
    Listed since: 04-02-2025

    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz of Littleton (606 mi away)4.96 out of 5 stars(22)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Littleton, CO / 606 miles away from Des Moines, IA

    2025 E450S4 Wagon040 Black101 Black MB-TexOptionsDA0 MBUX Superscreen Package $1,500 219 Selfie and video camera 529 MBUX multimedia system 860...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB6SA149100
    Stock: 250619
    Listed since: 04-01-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Tonka Brown/Black Nappa premium leatherTonka Brown/Black Nappa premium leather
    • Mercedes-Benz of Littleton (606 mi away)4.96 out of 5 stars(22)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Littleton, CO / 606 miles away from Des Moines, IA

    2025 E53EW4885 MANUFAKTUR Moonlight White Metallic $1,750854 AMG nappa leather, two-tone tonka brown / black $2,990OptionsDX1 Exclusive Trim $2,45...

    Features and Specs:

    Listing Information:

    VIN: W1KLF6DB7SA168277
    Stock: 250812
    Listed since: 04-25-2025

    • Exterior color: Graphite Grey MetallicGraphite Grey Metallic
    • Interior color: Tonka Brown/Black leatherTonka Brown/Black leather
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Littleton (606 mi away)4.96 out of 5 stars(22)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Littleton, CO / 606 miles away from Des Moines, IA

    2025 E350W4831 Graphite Grey Metallic $750104 Tonka Brown/ Black MB-TexOptionsDA0 MBUX Superscreen Package $1,500 219 Selfie and video camera 52...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB0SA117640
    Stock: 250672
    Listed since: 04-29-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Macchiato Beige/Black leatherMacchiato Beige/Black leather
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz of Huntsville (608 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Huntsville, AL / 608 miles away from Des Moines, IA

    Polar White 2025 Mercedes-Benz E-Class E 450 4MATIC® 4MATIC® 9-Speed Automatic 3.0L I6 Turbo This vehicle is nicely equipped with, 4MATIC®, Active Dis...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB3SA085484
    Stock: S0152
    Listed since: 10-31-2024

    • Exterior color: Sonoran Brown MetallicSonoran Brown Metallic
    • Interior color: Macchiato Beige/Black leatherMacchiato Beige/Black leather
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Huntsville (608 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Huntsville, AL / 608 miles away from Des Moines, IA

    Sonoran Brown 2025 Mercedes-Benz E-Class E 350 RWD 9-Speed Automatic 2.0L I4 Turbocharged This vehicle is nicely equipped with, 2.0L I4 Turbocharged, ...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB5SA157357
    Stock: S0359
    Listed since: 03-24-2025

    • Exterior color: MANUFAKTUR Patagonia Red MetallicMANUFAKTUR Patagonia Red Metallic
    • Interior color: Black w/Red Stitching leatherette/sueded microfiberBlack w/Red Stitching leatherette/sueded microfiber
    • Mercedes-Benz of Huntsville (608 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Huntsville, AL / 608 miles away from Des Moines, IA

    Patagonia Red 2025 Mercedes-Benz E-Class E 53 AMG® 4MATIC® 4MATIC® 9-Speed Automatic 3.0L I6 Turbo This vehicle is nicely equipped with, 3.0L I6 Turbo...

    Features and Specs:

    Listing Information:

    VIN: W1KLF6DB0SA111306
    Stock: S0162
    Listed since: 11-11-2024

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatherBlack leather
    • 22 City / 31 Hwy MPG
    • Mercedes-Benz of Huntsville (608 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Huntsville, AL / 608 miles away from Des Moines, IA

    Polar White 2025 Mercedes-Benz E-Class E 450 4MATIC® 4MATIC® 9-Speed Automatic 3.0L I6 Turbo This vehicle is nicely equipped with, 4MATIC®.22/31 Cit...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLF6BB6SA168600
    Stock: S0420
    Listed since: 04-29-2025

  • Stock photo**
    • Exterior color: BlackBlack
    • Interior color: Macchiato Beige/Black leatheretteMacchiato Beige/Black leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Huntsville (608 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Huntsville, AL / 608 miles away from Des Moines, IA

    Black 2025 Mercedes-Benz E-Class E 350 4MATIC® 4MATIC® 9-Speed Automatic 2.0L I4 Turbocharged This vehicle is nicely equipped with, 2.0L I4 Turbocharg...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB6SA170682
    Stock: S0419
    Listed since: 04-29-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Macchiato Beige/Black leatheretteMacchiato Beige/Black leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Huntsville (608 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Huntsville, AL / 608 miles away from Des Moines, IA

    Polar White 2025 Mercedes-Benz E-Class E 350 4MATIC® 4MATIC® 9-Speed Automatic 2.0L I4 Turbocharged This vehicle is nicely equipped with, 2.0L I4 Turb...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB6SA131185
    Stock: S0254
    Listed since: 01-20-2025

    • Exterior color: MANUFAKTUR Patagonia Red MetallicMANUFAKTUR Patagonia Red Metallic
    • Interior color: Macchiato Beige/Black leatherMacchiato Beige/Black leather
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Huntsville (608 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Huntsville, AL / 608 miles away from Des Moines, IA

    Patagonia Red 2025 Mercedes-Benz E-Class E 350 RWD 9-Speed Automatic 2.0L I4 Turbocharged This vehicle is nicely equipped with, 2.0L I4 Turbocharged, ...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB7SA162205
    Stock: S0384
    Listed since: 04-04-2025

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Macchiato Beige/Black leatherMacchiato Beige/Black leather
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz of Huntsville (608 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Huntsville, AL / 608 miles away from Des Moines, IA

    Moonlight White 2025 Mercedes-Benz E-Class E 450 4MATIC® 4MATIC® 9-Speed Automatic 3.0L I6 Turbo This vehicle is nicely equipped with, 4MATIC®, Active...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB2SA122251
    Stock: S0203
    Listed since: 12-02-2024

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Huntsville (608 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Huntsville, AL / 608 miles away from Des Moines, IA

    Polar White 2025 Mercedes-Benz E-Class E 350 RWD 9-Speed Automatic 2.0L I4 Turbocharged This vehicle is nicely equipped with, 2.0L I4 Turbocharged.2...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GBXSA159346
    Stock: S0425
    Listed since: 05-05-2025

Showing 43 - 63 out of 1,047 listings
TrimMPGEngineStarting Price
2025 Mercedes-Benz E-Class E 450 4MATIC All-Terrain 4dr Wagon AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A)22 - 316-cylinders (mild hybrid)$80,345
2025 Mercedes-Benz E-Class E 350 4MATIC 4dr Sedan AWD (2.0L 4cyl Turbo gas/electric mild hybrid 9A)24 - 334-cylinders (mild hybrid)$67,345
2025 Mercedes-Benz E-Class AMG E 53 HYBRID 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)N/A6-cylinders (plug-in hybrid)$99,825
2025 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo gas/electric mild hybrid 9A)25 - 334-cylinders (mild hybrid)$66,505
2025 Mercedes-Benz E-Class E 450 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A)22 - 316-cylinders (mild hybrid)$73,565

More about the Mercedes-Benz E-Class

Edmunds has 1,047 New Mercedes-Benz E-Classes for sale near you, including a 2025 E-Class E 350 Sedan and a 2025 E-Class AMG E 53 HYBRID Sedan ranging in price from $66,505 to $101,410.

How much is a new 2025 Mercedes-Benz E-Class in Des Moines, IA?

A new 2025 Mercedes-Benz E-Class starts at $66,505 (including destination charge) in Des Moines, IA. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Mercedes-Benz E-Class Wagon cost in Des Moines, IA?

A new 2025 Mercedes-Benz E-Class Wagon starts at $80,345 in Des Moines, IA. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Mercedes-Benz E-Class Sedan which starts at $66,505.
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