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    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatherBlack leather
    • 22 City / 31 Hwy MPG
    • Mercedes-Benz of Gainesville (1,041 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
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    Located in Gainesville, FL / 1,041 miles away from Des Moines, IA

    Polar White 2025 Mercedes-Benz E-Class E 450 4MATIC® 4MATIC® 9-Speed Automatic 3.0L I6 TurboCALL OR EMAIL TODAY TO CHECK AVAILABILITY AND ADDITIONAL...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLF6BBXSA122669
    Stock: A122669
    Listed since: 03-31-2025

    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Gainesville (1,041 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
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    Located in Gainesville, FL / 1,041 miles away from Des Moines, IA

    Black 2025 Mercedes-Benz E-Class E 350 RWD 9-Speed Automatic 2.0L I4 TurbochargedCALL OR EMAIL TODAY TO CHECK AVAILABILITY AND ADDITIONAL OPTIONS. 2...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB2SA162404
    Stock: A162404
    Listed since: 06-12-2025

    • Exterior color: BlackBlack
    • Interior color: BlackBlack
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz Of Massapequa (1,057 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Amityville, NY / 1,057 miles away from Des Moines, IA

    2025 Mercedes-Benz E-Class E 350 4MATIC� 2.0L I4 Turbocharged 4MATIC� 9-Speed Automatic Black2.0L I4 Turbocharged, 4MATIC�.Thank you for choosing Merc...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB5SA172746
    Stock: SA172746
    Listed since: 06-30-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Tonka Brown/BlackTonka Brown/Black
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz Of Massapequa (1,057 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Amityville, NY / 1,057 miles away from Des Moines, IA

    2025 Mercedes-Benz E-Class E 450 4MATIC� 3.0L I6 Turbo 4MATIC� 9-Speed Automatic White4MATIC�.Thank you for choosing Mercedes-Benz of Massapequa, Long...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB5SA140016
    Stock: SA140016
    Listed since: 01-29-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Macchiato Beige/BlackMacchiato Beige/Black
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz Of Massapequa (1,057 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Amityville, NY / 1,057 miles away from Des Moines, IA

    2025 Mercedes-Benz E-Class E 450 4MATIC� 3.0L I6 Turbo 4MATIC� 9-Speed Automatic White4MATIC�.Thank you for choosing Mercedes-Benz of Massapequa, Long...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB8SA139779
    Stock: SA139779
    Listed since: 01-15-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: BlackBlack
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz Of Massapequa (1,057 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Amityville, NY / 1,057 miles away from Des Moines, IA

    2025 Mercedes-Benz E-Class E 350 4MATIC� 2.0L I4 Turbocharged 4MATIC� 9-Speed Automatic Black2.0L I4 Turbocharged, 4MATIC�.Thank you for choosing Merc...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB1SA161436
    Stock: SA161436
    Listed since: 06-23-2025

    • Exterior color: MANUFAKTUR Alpine GreyMANUFAKTUR Alpine Grey
    • Interior color: Black Nappa premium leatherBlack Nappa premium leather
    • Mercedes-Benz Of Massapequa (1,057 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Amityville, NY / 1,057 miles away from Des Moines, IA

    2025 Mercedes-Benz E-Class E 53 AMG� 4MATIC� 3.0L I6 Turbo 4MATIC� 9-Speed Automatic Gray3.0L I6 Turbo, 4MATIC�.Thank you for choosing Mercedes-Benz o...

    Features and Specs:

    Listing Information:

    VIN: W1KLF6DB4SA136032
    Stock: SA136032
    Listed since: 01-10-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Tonka Brown/Black Nappa premium leatherTonka Brown/Black Nappa premium leather
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz Of Massapequa (1,057 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Amityville, NY / 1,057 miles away from Des Moines, IA

    2025 Mercedes-Benz E-Class E 450 4MATIC� 3.0L I6 Turbo 4MATIC� 9-Speed Automatic Black4MATIC�.Thank you for choosing Mercedes-Benz of Massapequa, Long...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB9SA084680
    Stock: SA084680
    Listed since: 10-07-2024

    • Exterior color: Polar WhitePolar White
    • Interior color: Macchiato Beige/Black leatheretteMacchiato Beige/Black leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Daytona Beach (1,111 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Daytona Beach, FL / 1,111 miles away from Des Moines, IA

    2025 Mercedes-Benz E 350 4D Sedan 2.0L I4 Turbocharged RWD 9-Speed Automatic Polar WhiteThis vehicle Includes the Following Features and Options: 4-Wh...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB1SA162183
    Stock: SA162183
    Listed since: 06-12-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Daytona Beach (1,111 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Daytona Beach, FL / 1,111 miles away from Des Moines, IA

    2025 Mercedes-Benz E 350 4D Sedan 2.0L I4 Turbocharged RWD 9-Speed Automatic Polar WhiteThis vehicle Includes the Following Features and Options: 4-Wh...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB0SA136917
    Stock: SA136917
    Listed since: 04-17-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black leatherBlack leather
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of Daytona Beach (1,111 mi away)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Daytona Beach, FL / 1,111 miles away from Des Moines, IA

    2025 Mercedes-Benz E 350 4D Sedan 2.0L I4 Turbocharged RWD 9-Speed Automatic ObsidianThis vehicle Includes the Following Features and Options: 4-Wheel...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB6SA171025
    Stock: SA171025
    Listed since: 05-08-2025

    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of North Orlando (1,126 mi away)4.2 out of 5 stars(10)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sanford, FL / 1,126 miles away from Des Moines, IA

    Dual Moonroof,Wheels: 19" Multi-Spoke Light-Alloy,Navigation System,Ventilated Front Seats,All-Season Floor Mats (4-Piece),Keyless Start,First Aid Kit...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB2SA159468
    Stock: SA159468
    Listed since: 06-13-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of North Orlando (1,126 mi away)4.2 out of 5 stars(10)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sanford, FL / 1,126 miles away from Des Moines, IA

    Pinnacle Trim,Multicontour Seating Package,Driver Assistance Package,Mbux Superscreen Package,Wheels: 19" Amg ® 5-Twin-Spoke Light-Alloy W/Black,D...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB0SA129577
    Stock: SA129577
    Listed since: 01-27-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of North Orlando (1,126 mi away)4.2 out of 5 stars(10)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sanford, FL / 1,126 miles away from Des Moines, IA

    Dual Moonroof,Wheels: 19" 5-Spoke Light-Alloy (R82),Navigation System,Winter Package,All-Season Floor Mats (4-Piece),Wheel Locking Bolts,Natural Grain...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB1SA128826
    Stock: SA128826
    Listed since: 05-30-2025

    • Exterior color: BlackBlack
    • Interior color: Macchiato Beige/Black leatheretteMacchiato Beige/Black leatherette
    • 25 City / 33 Hwy MPG
    • Mercedes-Benz of North Orlando (1,126 mi away)4.2 out of 5 stars(10)
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Sanford, FL / 1,126 miles away from Des Moines, IA

    Natural Grain Brown Maple Wood Trim W/Alum Lines,Wheels: 19" Amg ® 5-Twin-Spoke Light-Alloy W/Black,Dual Moonroof,Navigation System,Ventilated Fro...

    Features and Specs:

    28 Combined MPG (25 City/33 Highway)

    Listing Information:

    VIN: W1KLF4GB8SA170121
    Stock: SA170121
    Listed since: 06-20-2025

    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Black leatherBlack leather
    • 7 Seats, 22 City / 31 Hwy MPG
    • Mercedes-Benz of North Orlando (1,126 mi away)4.2 out of 5 stars(10)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Sanford, FL / 1,126 miles away from Des Moines, IA

    Black; Leather Upholstery,Leather Package,Panoramic Roof,Leather Seats,Navigation System,Winter Package,Wheel Locking Bolts,Keyless Start,Rear Spoiler...

    Features and Specs:

    25 Combined MPG (22 City/31 Highway)

    Listing Information:

    VIN: W1KLH6FB4SA133820
    Stock: SA133820
    Listed since: 05-29-2025

    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Wesley Chapel (1,126 mi away)4.26 out of 5 stars(19)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wesley Chapel, FL / 1,126 miles away from Des Moines, IA

    Dual Moonroof,Wheels: 19" Multi-Spoke Light-Alloy,Navigation System,Wheel Locking Bolts,Keyless Start,First Aid Kit,Black,Black; Mb-Tex Upholstery

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB7SA088170
    Stock: SA088170
    Listed since: 09-17-2024

    • Exterior color: BlackBlack
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Wesley Chapel (1,126 mi away)4.26 out of 5 stars(19)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wesley Chapel, FL / 1,126 miles away from Des Moines, IA

    Dual Moonroof,Wheels: 19" Multi-Spoke Light-Alloy,Navigation System,Winter Package,Wheel Locking Bolts,Keyless Start,First Aid Kit,Black,Black; Mb-Tex...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB5SA089611
    Stock: SA089611
    Listed since: 09-17-2024

    • Exterior color: BlackBlack
    • Interior color: Macchiato Beige/Black leatheretteMacchiato Beige/Black leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Wesley Chapel (1,126 mi away)4.26 out of 5 stars(19)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wesley Chapel, FL / 1,126 miles away from Des Moines, IA

    Natural Grain Brown Maple Wood Trim W/Alum Lines,Wheels: 19" Amg ® 5-Twin-Spoke Light-Alloy W/Black,Dual Moonroof,Navigation System,Ventilated Fro...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB4SA084237
    Stock: SA084237
    Listed since: 09-17-2024

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Wesley Chapel (1,126 mi away)4.26 out of 5 stars(19)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wesley Chapel, FL / 1,126 miles away from Des Moines, IA

    Dual Moonroof,Wheels: 19" 5-Spoke Light-Alloy (R82),Navigation System,Winter Package,All-Season Floor Mats (4-Piece),Wheel Locking Bolts,Natural Grain...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB8SA091725
    Stock: SA091725
    Listed since: 05-29-2025

    • Exterior color: Polar WhitePolar White
    • Interior color: Black leatheretteBlack leatherette
    • 24 City / 33 Hwy MPG
    • Mercedes-Benz of Wesley Chapel (1,126 mi away)4.26 out of 5 stars(19)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wesley Chapel, FL / 1,126 miles away from Des Moines, IA

    Dual Moonroof,Wheels: 19" 5-Spoke Light-Alloy (R82),Navigation System,Winter Package,All-Season Floor Mats (4-Piece),Wheel Locking Bolts,Natural Grain...

    Features and Specs:

    27 Combined MPG (24 City/33 Highway)

    Listing Information:

    VIN: W1KLF4HB1SA092201
    Stock: SA092201
    Listed since: 03-31-2025

Showing 400 - 420 out of 1,001 listings
TrimMPGEngineStarting Price
2025 Mercedes-Benz E-Class E 450 4MATIC 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A)22 - 316-cylinders (mild hybrid)$76,110
2025 Mercedes-Benz E-Class E 350 4dr Sedan (2.0L 4cyl Turbo gas/electric mild hybrid 9A)25 - 334-cylinders (mild hybrid)$64,855
2025 Mercedes-Benz E-Class E 350 4MATIC 4dr Sedan AWD (2.0L 4cyl Turbo gas/electric mild hybrid 9A)24 - 334-cylinders (mild hybrid)$66,895
2025 Mercedes-Benz E-Class E 450 4MATIC All-Terrain 4dr Wagon AWD (3.0L 6cyl Turbo gas/electric mild hybrid 9A)22 - 316-cylinders (mild hybrid)$79,915
2025 Mercedes-Benz E-Class AMG E 53 HYBRID 4dr Sedan AWD (3.0L 6cyl Turbo gas/electric plug-in hybrid 9A)N/A6-cylinders (plug-in hybrid)$106,605

More about the Mercedes-Benz E-Class

Edmunds has 1,001 New Mercedes-Benz E-Classes for sale near you, including a 2025 E-Class E 350 Sedan and a 2025 E-Class AMG E 53 HYBRID Sedan ranging in price from $64,855 to $106,605.

How much is a new 2025 Mercedes-Benz E-Class in Des Moines, IA?

A new 2025 Mercedes-Benz E-Class starts at $64,855 (including destination charge) in Des Moines, IA. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Mercedes-Benz E-Class Sedan cost in Des Moines, IA?

A new 2025 Mercedes-Benz E-Class Sedan starts at $64,855 in Des Moines, IA. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Mercedes-Benz E-Class Wagon which starts at $79,915.
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