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    • Exterior color: CaviarCaviar
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Palomino Nuluxe Artificial Leather. 2025 Lexus RX 350 Premium 350 Premium Caviar 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Automatic 21/28 Cit...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC121563
    Stock: R5121563
    Listed since: 09-16-2025

    • Exterior color: Nightfall MicaNightfall Mica
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Palomino Nuluxe Artificial Leather. 2025 Lexus RX 350 Premium 350 Premium Mica 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Automatic 21/28 City/...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA1SC114577
    Stock: R5114577
    Listed since: 07-25-2025

  • New Listing
    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Black premium leatherBlack premium leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    2.5L I4 DOHC 16V, AWD, Peppercorn W/Blk Semi-Ani. 2025 Lexus RX 350h Luxury 350h Luxury Matador Red 2.5L I4 DOHC 16V 37/34 City/Highway MPG CVT 37/34 ...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA5SC101733
    Stock: R5101733
    Listed since: 09-15-2025

    • Exterior color: CaviarCaviar
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    2.5L I4 DOHC 16V, AWD, Birch W/Blk Open Pore Nul Artificial Leather. 2025 Lexus RX 350h Premium 350h Premium Caviar 2.5L I4 DOHC 16V 37/34 City/Highwa...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCAXSC075971
    Stock: R5075971
    Listed since: 02-20-2025

    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Birch leatherBirch leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Birch W/Blk Open Pore Lth Leather. 2025 Lexus RX 350 Premium Plus 350 Premium Plus Matador Red 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Autom...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA6SC119483
    Stock: R5119483
    Listed since: 09-04-2025

  • Arriving Soon
    • Exterior color: CaviarCaviar
    • Interior color: Black leatherBlack leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Blk W/Blk Open Pore Lth Leather. 2025 Lexus RX 350 Premium Plus 350 Premium Plus Caviar 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Automatic 21...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC122705
    Stock: R5122705
    Listed since: 09-18-2025

  • Arriving Soon
    • Exterior color: Nori Green PearlNori Green Pearl
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    2.5L I4 DOHC 16V, AWD, Palomino Nuluxe Artificial Leather. 2025 Lexus RX 350h Premium 350h Premium Green 2.5L I4 DOHC 16V 37/34 City/Highway MPG CVT 3...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA2SC103410
    Stock: R5103410
    Listed since: 09-18-2025

  • Arriving Soon
    • Exterior color: CaviarCaviar
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Birch W/Blk Open Pore Nul Artificial Leather. 2025 Lexus RX 350 Premium 350 Premium Caviar 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Automatic...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA4SC122589
    Stock: R5122589
    Listed since: 09-18-2025

  • Arriving Soon
    • Exterior color: CaviarCaviar
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    2.5L I4 DOHC 16V, AWD, Birch W/Blk Open Pore Nul Artificial Leather. 2025 Lexus RX 350h Premium 350h Premium Caviar 2.5L I4 DOHC 16V 37/34 City/Highwa...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA4SC102260
    Stock: R5102260
    Listed since: 09-16-2025

  • Arriving Soon
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Palomino Nuluxe Artificial Leather. 2025 Lexus RX 350 Premium 350 Premium White Pearl 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Automatic 21/2...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA8SC122451
    Stock: R5122451
    Listed since: 09-17-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Birch W/Blk Open Pore Nul Artificial Leather. 2025 Lexus RX 350 Premium 350 Premium White Pearl 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Auto...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA0SC120676
    Stock: R5120676
    Listed since: 09-10-2025

    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Birch W/Blk Open Pore Nul Artificial Leather. 2025 Lexus RX 350 Premium 350 Premium Gray 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Automatic 2...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC121739
    Stock: R5121739
    Listed since: 09-16-2025

    • Exterior color: Nori Green PearlNori Green Pearl
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Blk W/Blk Open Pore Nulux Artificial Leather. 2025 Lexus RX 350 Premium 350 Premium Green 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Automatic ...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA4SC120390
    Stock: R5120390
    Listed since: 09-09-2025

  • Arriving Soon
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Blk W/Blk Open Pore Nulux Artificial Leather. 2025 Lexus RX 350 Premium 350 Premium White Pearl 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Auto...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC121506
    Stock: R5121506
    Listed since: 09-16-2025

  • Arriving Soon
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    AWD, Blk W/Blk Open Pore Nulux Artificial Leather. 2025 Lexus RX 350 Premium 350 Premium Gray 2.4L I4 Turbo 21/28 City/Highway MPG 8-Speed Automatic 2...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC122566
    Stock: R5122566
    Listed since: 09-18-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Macadamia premium leatherMacadamia premium leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Wilmington (451 mi away)4.2 out of 5 stars(5)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wilmington, DE / 451 miles away from Myrtle Beach, SC

    2.5L I4 DOHC 16V, AWD, Macadamia W/Ash Bamboo Se. 2025 Lexus RX 350h Luxury 350h Luxury White Pearl 2.5L I4 DOHC 16V 37/34 City/Highway MPG CVT 37/34 ...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA4SC102193
    Stock: R5102193
    Listed since: 09-16-2025

  • New Listing
    Photos not available
    $58,659
    MSRP $58,659
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Atlantic City (454 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Egg Harbor Township, NJ / 454 miles away from Myrtle Beach, SC

    Our address is 3169 Fire Road, Egg Harbor Township NJ. Sales hours Mon-Thurs 9 am-7 pm Fri 9-6 Sat 9 am-4 pm Service Hours Mon-Fri 8 am-5:30 pm Sat 8 ...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC120209
    Stock: L19100
    Listed since: 09-21-2025

  • New Listing
    Stock photo**
    $58,700
    MSRP $58,700
    • Exterior color: CaviarCaviar
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Atlantic City (454 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Egg Harbor Township, NJ / 454 miles away from Myrtle Beach, SC

    Our address is 3169 Fire Road, Egg Harbor Township NJ. Sales hours Mon-Thurs 9 am-7 pm Fri 9-6 Sat 9 am-4 pm Service Hours Mon-Fri 8 am-5:30 pm Sat 8 ...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC120050
    Stock: L19096
    Listed since: 09-21-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Atlantic City (454 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Egg Harbor Township, NJ / 454 miles away from Myrtle Beach, SC

    Our address is 3169 Fire Road, Egg Harbor Township NJ. Sales hours Mon-Thurs 9 am-7 pm Fri 9-6 Sat 9 am-4 pm Service Hours Mon-Fri 8 am-5:30 pm Sat 8 ...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7SC119055
    Stock: L19085
    Listed since: 09-10-2025

    • Exterior color: Matador Red MicaMatador Red Mica
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Atlantic City (454 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Egg Harbor Township, NJ / 454 miles away from Myrtle Beach, SC

    Our address is 3169 Fire Road, Egg Harbor Township NJ. Sales hours Mon-Thurs 9 am-7 pm Fri 9-6 Sat 9 am-4 pm Service Hours Mon-Fri 8 am-5:30 pm Sat 8 ...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA7SC100289
    Stock: L19087
    Listed since: 09-10-2025

    • Exterior color: CaviarCaviar
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Atlantic City (454 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Egg Harbor Township, NJ / 454 miles away from Myrtle Beach, SC

    Our address is 3169 Fire Road, Egg Harbor Township NJ. Sales hours Mon-Thurs 9 am-7 pm Fri 9-6 Sat 9 am-4 pm Service Hours Mon-Fri 8 am-5:30 pm Sat 8 ...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA3SC098377
    Stock: L19062
    Listed since: 08-30-2025

Showing 337 - 357 out of 3,784 listings
TrimMPGEngineStarting Price
2025 Lexus RX 350 Premium 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$56,365
2025 Lexus RX 350h Luxury 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$68,865
2025 Lexus RX 350h Premium 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$57,634
2025 Lexus RX 350 Premium Plus 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$61,960
2025 Lexus RX 350 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$58,659
2025 Lexus RX 350h 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$68,065

More about the Lexus RX

Edmunds has 3,784 New Lexus RXes for sale near you, including a 2025 RX 350 Premium SUV and a 2025 RX 350h Luxury SUV ranging in price from $56,365 to $69,849.

How much is a new 2025 Lexus RX in Myrtle Beach, SC?

A new 2025 Lexus RX starts at $56,365 (including destination charge) in Myrtle Beach, SC. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Lexus RX SUV cost in Myrtle Beach, SC?

A new 2025 Lexus RX SUV starts at $56,365 in Myrtle Beach, SC. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Lexus RX Hybrid which starts at $60,434.
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