Skip to main content
Skip to Filters
3,115 listings
  • New Listing
    Stock photo**
    • Exterior color: Nightfall MicaNightfall Mica
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Brookfield (295 mi away)4.99 out of 5 stars(181)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Brookfield, WI / 295 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA0SC112237
    Stock: SC26B909
    Listed since: 06-27-2025

  • Arriving Soon
    Stock photo**
    • Exterior color: Nightfall MicaNightfall Mica
    • Interior color: Macadamia premium leatherMacadamia premium leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Brookfield (295 mi away)4.99 out of 5 stars(181)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Brookfield, WI / 295 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA1SC112201
    Stock: SC26C568
    Listed since: 06-26-2025

  • Stock photo**
    • Exterior color: CaviarCaviar
    • Interior color: Palomino leatherPalomino leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Brookfield (295 mi away)4.99 out of 5 stars(181)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Brookfield, WI / 295 miles away from Des Moines, IA

    SUMMER SALES EVENT GOING ON NOW!!!The Lexus RX has been ranked the number one selling SUV for over 20 straight years. Reliability and comfort come st...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7SC108606
    Stock: 28386
    Listed since: 06-09-2025

    • Exterior color: CaviarCaviar
    • Interior color: Birch leatherBirch leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Brookfield (295 mi away)4.99 out of 5 stars(181)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Brookfield, WI / 295 miles away from Des Moines, IA

    SUMMER SALES EVENT GOING ON NOW!!!The Lexus RX has been ranked the number one selling SUV for over 20 straight years. Reliability and comfort come st...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA8SC092087
    Stock: 28379
    Listed since: 06-09-2025

    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Brookfield (295 mi away)4.99 out of 5 stars(181)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Brookfield, WI / 295 miles away from Des Moines, IA

    SPRING SALES EVENT GOING ON NOW!!!The Lexus RX has been ranked the number one selling SUV for over 20 straight years. Reliability and comfort come st...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA1SC108939
    Stock: 28378
    Listed since: 06-09-2025

  • New Listing
    Stock photo**
    • Exterior color: IridiumIridium
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Brookfield (295 mi away)4.99 out of 5 stars(181)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Brookfield, WI / 295 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA1SC112344
    Stock: SC26B860
    Listed since: 06-27-2025

  • Arriving Soon
    Stock photo**
    • Exterior color: Nori Green PearlNori Green Pearl
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Brookfield (295 mi away)4.99 out of 5 stars(181)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Brookfield, WI / 295 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC112216
    Stock: 112216
    Listed since: 06-26-2025

  • Arriving Soon
    Stock photo**
    • Exterior color: Nightfall MicaNightfall Mica
    • Interior color: Macadamia leatherMacadamia leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Brookfield (295 mi away)4.99 out of 5 stars(181)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Brookfield, WI / 295 miles away from Des Moines, IA

    SUMMER SALES EVENT GOING ON NOW!!!The Lexus RX has been ranked the number one selling SUV for over 20 straight years. Reliability and comfort come st...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA5SC094654
    Stock: SC25C811
    Listed since: 06-25-2025

    • Exterior color: Ultra WhiteUltra White
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Brookfield (295 mi away)4.99 out of 5 stars(181)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Brookfield, WI / 295 miles away from Des Moines, IA

    SUMMER SALES EVENT GOING ON NOW!!!The Lexus RX has been ranked the number one selling SUV for over 20 straight years. Reliability and comfort come st...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA6SC107740
    Stock: 28328
    Listed since: 06-04-2025

    • Exterior color: IridiumIridium
    • Interior color: Palomino leatherPalomino leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Orland (298 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Orland Park, IL / 298 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC097619
    Stock: LX0784
    Listed since: 06-10-2025

    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Orland (298 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Orland Park, IL / 298 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA8SC111031
    Stock: LX0840
    Listed since: 06-19-2025

    • Exterior color: Grecian WaterGrecian Water
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Orland (298 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Orland Park, IL / 298 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7SC108072
    Stock: LX0727
    Listed since: 05-28-2025

  • Stock photo**
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Orland (298 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Orland Park, IL / 298 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA6SC110749
    Stock: LX0821
    Listed since: 06-16-2025

    • Exterior color: CaviarCaviar
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Orland (298 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Orland Park, IL / 298 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC110546
    Stock: LX0847
    Listed since: 06-17-2025

    • Exterior color: CaviarCaviar
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Orland (298 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Orland Park, IL / 298 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA5SC111083
    Stock: LX0839
    Listed since: 06-19-2025

  • New Listing
    Stock photo**
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Orland (298 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Orland Park, IL / 298 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCAXSC111743
    Stock: LX0867
    Listed since: 06-26-2025

  • New Listing
    • Exterior color: Copper CrestCopper Crest
    • Interior color: Black leatherBlack leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Orland (298 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Orland Park, IL / 298 miles away from Des Moines, IA

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC098177
    Stock: LX0818
    Listed since: 06-12-2025

    • Exterior color: CaviarCaviar
    • Interior color: Macadamia leatherMacadamia leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Highland Park (299 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Highland Park, IL / 299 miles away from Des Moines, IA

    Caviar 2025 Lexus RX 350 Premium Plus AWD 8-Speed Automatic 2.4L I4 Turbo21/28 City/Highway MPGLexus of Highland Park is a truly family-owned and...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCAXSC098105
    Stock: 250760
    Listed since: 06-06-2025

  • New Listing
    • Exterior color: IridiumIridium
    • Interior color: Black leatherBlack leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Highland Park (299 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Highland Park, IL / 299 miles away from Des Moines, IA

    Iridium 2025 Lexus RX 350 Premium Plus AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPGLexus of Highland Park is a truly...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA9SC108008
    Stock: 250806
    Listed since: 06-23-2025

    • Exterior color: Nori Green PearlNori Green Pearl
    • Interior color: Macadamia leatherMacadamia leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Highland Park (299 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Highland Park, IL / 299 miles away from Des Moines, IA

    Green Pearl 2025 Lexus RX 350h Premium Plus AWD CVT 2.5L I4 DOHC 16V37/34 City/Highway MPGLexus of Highland Park is a truly family-owned and oper...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA6SC076941
    Stock: 250761
    Listed since: 06-06-2025

  • New Listing
    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Highland Park (299 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Highland Park, IL / 299 miles away from Des Moines, IA

    Matador Red Mica 2025 Lexus RX 350 Premium AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPGLexus of Highland Park is a t...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA1SC109489
    Stock: 250803
    Listed since: 06-20-2025

Showing 169 - 189 out of 3,115 listings

Consumer Reviews for the Lexus RX

Read recent reviews for the Lexus RX
Overall Consumer Rating
4.2 out of 5 stars65 Reviews
Write a vehicle reviewSee all 65 reviews
  • 5 star
    (68%)
  • 4 star
    (9%)
  • 3 star
    (11%)
  • 2 star
    (5%)
  • 1 star
    (8%)
5 out of 5 stars

Lexus luxury

G. Blackwell, 03/14/2024
2024 Lexus RX 350h Luxury 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)
Too often a vehicle is judged by automotive "enthusiasts" who dwell on low 0-60 acceleration times and subsequently categorise the vehicle as preferred. After testing several vehicles I selected the Lexus rx350h. Plenty fast, handles exceptionally well, great on gas, oh, so comfortable, quiet, modern and a solid vehicle to boot with high resale value. Automotive reviewers provide an … insight into vehicles but most buyers have an innate sense of satisfaction and this vehicle meets all my needs.
Report abuse
TrimMPGEngineStarting Price
2025 Lexus RX 350 Premium 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$58,374
2025 Lexus RX 350 Luxury 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$66,825
2025 Lexus RX 350 Premium Plus 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$61,685
2025 Lexus RX 350h Premium Plus 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$62,570
2025 Lexus RX 350 F SPORT Design 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$60,455
2025 Lexus RX 350 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$58,784

More about the Lexus RX

Edmunds has 3,115 New Lexus RXes for sale near you, including a 2025 RX 350 Premium SUV and a 2025 RX 350 Luxury SUV ranging in price from $58,374 to $66,825.

How much is a new 2025 Lexus RX in Des Moines, IA?

A new 2025 Lexus RX starts at $58,374 (including destination charge) in Des Moines, IA. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Lexus RX SUV cost in Des Moines, IA?

A new 2025 Lexus RX SUV starts at $58,374 in Des Moines, IA. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Lexus RX Hybrid which starts at $62,570.
Filters
Skip to Results

Applied Filters3Active

Location

Search radiusNationwide
Search radius

Make & Model

Year

New / Used

Price & Payments

Price Rating

Body Type

Trim

Engine & Drivetrain

Exterior Color

Interior Color

Total Seating

Edmunds Review

Features

Options & Packages

MPG

Listing Details