Skip to FiltersReport abuse
3,015 listings
- $60,040MSRP $60,790
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Milwaukee (308 mi away)
Close
Located in Milwaukee, WI / 308 miles away from Des Moines, IA
SUMMER SALES EVENT GOING ON NOW!!!This is your chance to drive the number one selling suv for over 20 straight years. The RX is the definition of rel...
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA6SC106412
Stock: L20947
Listed since: 05-31-2025 - Arriving Soon$59,450MSRP $59,450
- Exterior color: CaviarCaviar
- Interior color: Birch leatheretteBirch leatherette
- 5 Seats, 37 City / 34 Hwy MPG
- Lexus of Milwaukee (308 mi away)
Close
Located in Milwaukee, WI / 308 miles away from Des Moines, IA
SUMMER SALES EVENT GOING ON NOW!!!This is your chance to drive the number one selling suv for over 20 straight years. The RX is the definition of rel...
Features and Specs:
36 Combined MPG (37 City/34 Highway)
Listing Information:
VIN: 2T2BBMCA0SC090138
Stock: L20916
Listed since: 05-06-2025 - New Listing$64,379MSRP $64,379
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Palomino leatherPalomino leather
- 5 Seats, 37 City / 34 Hwy MPG
- Lexus of Milwaukee (308 mi away)
Close
Located in Milwaukee, WI / 308 miles away from Des Moines, IA
SUMMER SALES EVENT GOING ON NOW!!!The Lexus RX has been ranked the number one selling SUV for over 20 straight years. Reliability and comfort come st...
Features and Specs:
36 Combined MPG (37 City/34 Highway)
Listing Information:
VIN: 2T2BBMCA1SC093890
Stock: L21018
Listed since: 06-27-2025 - Arriving Soon$59,715MSRP $60,465
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Milwaukee (308 mi away)
Close
Located in Milwaukee, WI / 308 miles away from Des Moines, IA
SUMMER SALES EVENT GOING ON NOW!!!This is your chance to drive the number one selling suv for over 20 straight years. The RX is the definition of rel...
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA5SC105655
Stock: L20918
Listed since: 05-02-2025 - $58,494MSRP
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Black leatheretteBlack leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
0085 2025 Lexus RX 350 Premium AWD 8-Speed Automatic 2.4L I4 Turbo21/28 City/Highway MPG
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA7SC107231
Stock: LM0461
Listed since: 05-17-2025 - $69,500MSRP
- Exterior color: IridiumIridium
- Interior color: Peppercorn premium leatherPeppercorn premium leather
- 5 Seats, 37 City / 34 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
01l2 2025 Lexus RX 350h Luxury AWD CVT 2.5L I4 DOHC 16V37/34 City/Highway MPG
Features and Specs:
36 Combined MPG (37 City/34 Highway)
Listing Information:
VIN: 2T2BBMCA2SC092361
Stock: LM0491
Listed since: 05-31-2025 - New Listing
- Exterior color: IridiumIridium
- Interior color: Macadamia leatherMacadamia leather
- 5 Seats, 37 City / 34 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
01l2 2025 Lexus RX AWD CVT 2.5L I4 DOHC 16VRecent Arrival! 37/34 City/Highway MPG
Features and Specs:
36 Combined MPG (37 City/34 Highway)
Listing Information:
VIN: 2T2BBMCAXSC094472
Stock: LM0543
Listed since: 06-26-2025 - New Listing$61,590MSRP $62,590
- Exterior color: Nori Green PearlNori Green Pearl
- Interior color: Black leatherBlack leather
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
06x4 2025 Lexus RX AWD 8-Speed Automatic 2.4L I4 Turbo21/28 City/Highway MPG
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA8SC108498
Stock: LM0539
Listed since: 06-03-2025 - $57,709MSRP
- Exterior color: CaviarCaviar
- Interior color: Birch leatheretteBirch leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
0223 2025 Lexus RX 350 Premium AWD 8-Speed Automatic 2.4L I4 Turbo21/28 City/Highway MPG
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA1SC107872
Stock: LM0468
Listed since: 05-29-2025 - New Listing$60,870MSRP
- Exterior color: IridiumIridium
- Interior color: Black leatheretteBlack leatherette
- 5 Seats, 37 City / 34 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
01l2 2025 Lexus RX 350h Premium AWD CVT 2.5L I4 DOHC 16VRecent Arrival! 37/34 City/Highway MPG
Features and Specs:
36 Combined MPG (37 City/34 Highway)
Listing Information:
VIN: 2T2BBMCA0SC094710
Stock: LM0546
Listed since: 06-26-2025 - $58,719MSRP $61,719
- Exterior color: Copper CrestCopper Crest
- Interior color: Black leatheretteBlack leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
04y5 2025 Lexus RX 350 F Sport AWD 8-Speed Automatic 2.4L I4 Turbo21/28 City/Highway MPG
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA5SC100245
Stock: LM0380
Listed since: 04-04-2025 - $58,934MSRP
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Palomino leatherettePalomino leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
0085 2025 Lexus RX 350 Premium AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA5SC111276
Stock: LM0530
Listed since: 06-20-2025 - $58,784MSRP
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Black leatheretteBlack leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
0085 2025 Lexus RX 350 Premium AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA1SC111548
Stock: LM0533
Listed since: 06-20-2025 - New Listing$69,304MSRP
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Black leatheretteBlack leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
0085 2025 Lexus RX 350 Luxury AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA2SC112305
Stock: LM0549
Listed since: 06-28-2025 - Arriving Soon$64,359MSRP
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Merrillville (321 mi away)(3)
Close
Located in Merrillville, IN / 321 miles away from Des Moines, IA
0223 2025 Lexus RX 350 F Sport Handling AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA8SC111563
Stock: LM0552
Listed since: 06-28-2025 - $66,998MSRP $68,020
- Exterior color: CaviarCaviar
- Interior color: Black premium leatherBlack premium leather
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Wichita (331 mi away)
Close
Located in Wichita, KS / 331 miles away from Des Moines, IA
Delivers 28 Highway MPG and 21 City MPG! This Lexus RX delivers a 2.4L I4 Turbo engine powering this Automatic transmission. Front And Rear Anti-Roll ...
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA7SC109478
Stock: 54L1300N
Listed since: 06-16-2025 - $58,645MSRP $58,645
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Birch leatheretteBirch leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Wichita (331 mi away)
Close
Located in Wichita, KS / 331 miles away from Des Moines, IA
Boasts 28 Highway MPG and 21 City MPG! This Lexus RX delivers a 2.4L I4 Turbo engine powering this Automatic transmission. Front And Rear Anti-Roll Ba...
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA7SC110727
Stock: 54L1329N
Listed since: 06-29-2025 - New Listing$69,700MSRP $69,700
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Black premium leatherBlack premium leather
- 5 Seats, 37 City / 34 Hwy MPG
- Lexus of Wichita (331 mi away)
Close
Located in Wichita, KS / 331 miles away from Des Moines, IA
Boasts 34 Highway MPG and 37 City MPG! This Lexus RX delivers a 2.5L I4 DOHC 16V engine powering this Variable transmission. Front And Rear Anti-Roll ...
Features and Specs:
36 Combined MPG (37 City/34 Highway)
Listing Information:
VIN: 2T2BBMCA7SC095031
Stock: 54L1355N
Listed since: 06-29-2025 - $70,529MSRP $70,529
- Exterior color: IridiumIridium
- Interior color: Black leatheretteBlack leatherette
- 5 Seats, 37 City / 34 Hwy MPG
- Lexus of Wichita (331 mi away)
Close
Located in Wichita, KS / 331 miles away from Des Moines, IA
Scores 34 Highway MPG and 37 City MPG! This Lexus RX delivers a 2.5L I4 DOHC 16V engine powering this Variable transmission. Front And Rear Anti-Roll ...
Features and Specs:
36 Combined MPG (37 City/34 Highway)
Listing Information:
VIN: 2T2BBMCA7SC094378
Stock: 54L1343N
Listed since: 06-29-2025 - $57,998MSRP $58,645
- Exterior color: IridiumIridium
- Interior color: Birch leatheretteBirch leatherette
- 5 Seats, 21 City / 28 Hwy MPG
- Lexus of Wichita (331 mi away)
Close
Located in Wichita, KS / 331 miles away from Des Moines, IA
Delivers 28 Highway MPG and 21 City MPG! This Lexus RX delivers a 2.4L I4 Turbo engine powering this Automatic transmission. Front And Rear Anti-Roll ...
Features and Specs:
24 Combined MPG (21 City/28 Highway)
Listing Information:
VIN: 2T2BAMCA4SC108594
Stock: 54L1321N
Listed since: 06-12-2025 - $64,030MSRP $64,030
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Black leatheretteBlack leatherette
- 5 Seats, 37 City / 34 Hwy MPG
- Lexus of Wichita (331 mi away)
Close
Located in Wichita, KS / 331 miles away from Des Moines, IA
Delivers 34 Highway MPG and 37 City MPG! This Lexus RX boasts a 2.5L I4 DOHC 16V engine powering this Variable transmission. Front And Rear Anti-Roll ...
Features and Specs:
36 Combined MPG (37 City/34 Highway)
Listing Information:
VIN: 2T2BBMCA3SC092319
Stock: 54L1303N
Listed since: 06-22-2025
Showing 253 - 273 out of 3,015 listings
Consumer Reviews for the Lexus RX
Read recent reviews for the Lexus RX
Lexus luxury
G. Blackwell, 03/14/2024
2024 Lexus RX 350h Luxury 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)
Too often a vehicle is judged by automotive "enthusiasts" who dwell on low 0-60 acceleration times and subsequently categorise the vehicle as preferred. After testing several vehicles I selected the Lexus rx350h. Plenty fast, handles exceptionally well, great on gas, oh, so comfortable, quiet, modern and a solid vehicle to boot with high resale value. Automotive reviewers provide an … insight into vehicles but most buyers have an innate sense of satisfaction and this vehicle meets all my needs.
| Trim | MPG | Engine | Starting Price |
|---|---|---|---|
| 2025 Lexus RX 350 F SPORT Design 4dr SUV AWD (2.4L 4cyl Turbo 8A) | 21 - 28 | 4-cylinders (gas) | $60,465 |
| 2025 Lexus RX 350h Premium 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT) | 37 - 34 | 4-cylinders (hybrid) | $59,450 |
| 2025 Lexus RX 350h Premium Plus 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT) | 37 - 34 | 4-cylinders (hybrid) | $63,315 |
| 2025 Lexus RX 350 Premium 4dr SUV AWD (2.4L 4cyl Turbo 8A) | 21 - 28 | 4-cylinders (gas) | $57,709 |
| 2025 Lexus RX 350h Luxury 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT) | 37 - 34 | 4-cylinders (hybrid) | $69,500 |
| 2025 Lexus RX 350 Premium Plus 4dr SUV AWD (2.4L 4cyl Turbo 8A) | 21 - 28 | 4-cylinders (gas) | $62,590 |
| 2025 Lexus RX 350 4dr SUV AWD (2.4L 4cyl Turbo 8A) | 21 - 28 | 4-cylinders (gas) | $69,304 |
| 2025 Lexus RX 350 F SPORT Handling 4dr SUV AWD (2.4L 4cyl Turbo 8A) | 21 - 28 | 4-cylinders (gas) | $64,359 |
| 2025 Lexus RX 350 Luxury 4dr SUV AWD (2.4L 4cyl Turbo 8A) | 21 - 28 | 4-cylinders (gas) | $68,020 |
| 2025 Lexus RX 350h 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT) | 37 - 34 | 4-cylinders (hybrid) | $64,030 |
More about the Lexus RX
Edmunds has 3,015 New Lexus RXes for sale near you, including a 2025 RX 350 Premium SUV and a 2025 RX 350h SUV ranging in price from $57,709 to $70,529.
How much is a new 2025 Lexus RX in Des Moines, IA?
- A new 2025 Lexus RX starts at $57,709 (including destination charge) in Des Moines, IA. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus RX SUV cost in Des Moines, IA?
- A new 2025 Lexus RX SUV starts at $57,709 in Des Moines, IA. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.Other versions include:
2025 Lexus RX Hybrid which starts at $64,030.
Filters
Skip to Results