How much is a new 2025 Lexus IS in Saint Charles, MO?

A new 2025 Lexus IS starts at $48,778 (including destination charge) in Saint Charles, MO. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next. Learn more

How much does a 2025 Lexus IS Sedan cost in Saint Charles, MO?

A new 2025 Lexus IS Sedan starts at $48,778 in Saint Charles, MO. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds. Learn more

How much is a brand-new Lexus IS in Saint Charles, MO?

A brand-new Lexus IS starts at $48,778 in Saint Charles, MO. The price can change based on a number of factors such as location, model year, trim level and options. Learn more

How much does a 2025 Lexus IS cost in Saint Charles, MO?

A 2025 Lexus IS costs from $48,778 to about $61,880 in Saint Charles, MO. The prices will vary based on trim level, installed options and dealership discounts. Learn more

New Lexus IS for Sale in Saint Charles, MO

Name: Lexus IS
Brand: Lexus
Rating: 4.4 (13 reviews)

925 listings

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Arriving Soon
Stock photo^**
2025 Lexus IS
350 F SPORT Sedan
$53,923
MSRP $53,923
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (17 mi away)5 out of 5 stars(8)
- Home delivery*
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Manchester, MO / 17 miles away from Saint Charles, MO
Infrared 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V 19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21S5040418
Stock: 35244
Listed since: 03-29-2025
New Listing
2025 Lexus IS
350 F SPORT Sedan
$53,688
MSRP $53,688
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Reliable Lexus (189 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Navigation
- Sunroof/Moonroof
Close
Located in Springfield, MO / 189 miles away from Saint Charles, MO
Recent Arrival! 2025 Incognito Lexus IS 4D Sedan 350 F SPORT 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD 19/26 City/Highway MPG 19/26 City/Highw...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29S5038626
Stock: S5038626
Listed since: 05-15-2025
Arriving Soon
2025 Lexus IS
350 F SPORT Sedan
$54,883
MSRP $54,883
- Exterior color: InfraredInfrared
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Reliable Lexus (189 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Navigation
- Sunroof/Moonroof
Close
Located in Springfield, MO / 189 miles away from Saint Charles, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29S5040599
Stock: 040599
Listed since: 05-06-2025
Arriving Soon
2025 Lexus IS
350 F SPORT Sedan
$54,384
MSRP $54,384
- Exterior color: IridiumIridium
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Reliable Lexus (189 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Navigation
- Sunroof/Moonroof
Close
Located in Springfield, MO / 189 miles away from Saint Charles, MO
Recent Arrival! 2025 Iridium Lexus IS 4D Sedan 350 F SPORT 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD 19/26 City/Highway MPG 19/26 City/Highway...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28S5040139
Stock: S5040139
Listed since: 04-08-2025
New Listing
Stock photo^**
2025 Lexus IS
350 F SPORT Design Sedan
$50,428
MSRP
- Exterior color: CaviarCaviar
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Orland (236 mi away)5 out of 5 stars(2)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Orland Park, IL / 236 miles away from Saint Charles, MO

Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E25S5040724
Stock: LX0716
Listed since: 05-16-2025
New Listing
Stock photo^**
2025 Lexus IS
350 F SPORT Design Sedan
$50,428
MSRP
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Orland (236 mi away)5 out of 5 stars(2)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Orland Park, IL / 236 miles away from Saint Charles, MO

Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E23S5040706
Stock: LX0712
Listed since: 05-15-2025
New Listing
Stock photo^**
2025 Lexus IS
350 F SPORT Sedan
$57,178
MSRP
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Orland (236 mi away)5 out of 5 stars(2)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Orland Park, IL / 236 miles away from Saint Charles, MO

Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27S5040648
Stock: LX0707
Listed since: 05-14-2025
Stock photo^**
2025 Lexus IS
350 F SPORT Sedan
$55,450
MSRP
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Merrillville (244 mi away)5 out of 5 stars(3)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Merrillville, IN / 244 miles away from Saint Charles, MO
0223 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VRecent Arrival! 19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XS5040630
Stock: LM0435
Listed since: 05-05-2025
Stock photo^**
2025 Lexus IS
350 F SPORT Design Sedan
$52,998
MSRP $52,998
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Woodfield Lexus (255 mi away)4.97 out of 5 stars(35)
- AWD/4WD
- Back-up camera
- Bluetooth
- Navigation
- Sunroof/Moonroof
Close
Located in Schaumburg, IL / 255 miles away from Saint Charles, MO
F SPORT DESIGN PACKAGE|-INC: STD EQUIP.|ACCESSORY PACKAGE|CARGO NET|REAR BUMPER APPLIQUE|KEY GLOVES|CARPET TRUNK MAT|WHEEL LOCKS|NAVIGATION PACKAGE|PR...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E23S5040642
Stock: 250907
Listed since: 05-02-2025
Arriving Soon
Stock photo^**
2025 Lexus IS
350 F SPORT Sedan
$58,198
MSRP $58,198
- Exterior color: InfraredInfrared
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (258 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Chicago, IL / 258 miles away from Saint Charles, MO

Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XS5040580
Stock: S1111
Listed since: 05-16-2025
2025 Lexus IS
350 F SPORT Design Sedan
$48,778
MSRP $48,778
- Exterior color: IridiumIridium
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Arlington (262 mi away)1 out of 5 stars(2)
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
- Blind Spot Monitorin...
Close
Located in Arlington Heights, IL / 262 miles away from Saint Charles, MO
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B21S5083719
Stock: AL3429
Listed since: 02-11-2025
Arriving Soon
Stock photo^**
2025 Lexus IS
350 F SPORT Design Sedan
$50,098
MSRP $50,098
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (262 mi away)1 out of 5 stars(2)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Arlington Heights, IL / 262 miles away from Saint Charles, MO
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E21S5040638
Stock: AL3813
Listed since: 05-01-2025
Stock photo^**
2025 Lexus IS
350 F SPORT Design Sedan
$50,630
MSRP $50,630
- Exterior color: InfraredInfrared
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (262 mi away)1 out of 5 stars(2)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Arlington Heights, IL / 262 miles away from Saint Charles, MO
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E23S5040768
Stock: 3448
Listed since: 05-08-2025
Stock photo^**
2025 Lexus IS
350 F SPORT Design Sedan
$50,535
MSRP $50,535
- Exterior color: IridiumIridium
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (262 mi away)1 out of 5 stars(2)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Arlington Heights, IL / 262 miles away from Saint Charles, MO
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E20S5040825
Stock: 3442
Listed since: 05-14-2025
2025 Lexus IS
350 F SPORT Sedan
$54,988
MSRP $54,988
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Highland Park (270 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Highland Park, IL / 270 miles away from Saint Charles, MO
Infra Red 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V19/26 City/Highway MPGLexus of Highland Park is a truly fami...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28S5040626
Stock: 250632
Listed since: 05-01-2025
2025 Lexus IS
350 F SPORT Sedan
$61,880
MSRP $61,880
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Lexus of Highland Park (270 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Highland Park, IL / 270 miles away from Saint Charles, MO
Gray 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V19/26 City/Highway MPGLexus of Highland Park is a truly family-ow...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XS5040319
Stock: 250605
Listed since: 04-22-2025
Arriving Soon
Stock photo^**
2025 Lexus IS
350 F SPORT Sedan
$58,420
MSRP $59,170
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (314 mi away)4.99 out of 5 stars(174)
- Five Star Dealer
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Brookfield, WI / 314 miles away from Saint Charles, MO
SPRING SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27S5040598
Stock: 040598
Listed since: 05-01-2025
2025 Lexus IS
350 F SPORT Design Sedan
$49,445
MSRP $50,195
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (314 mi away)4.99 out of 5 stars(174)
- Five Star Dealer
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Brookfield, WI / 314 miles away from Saint Charles, MO
SPRING SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E28S5039907
Stock: 28088
Listed since: 04-07-2025
New Listing
Stock photo^**
2025 Lexus IS
350 F SPORT Design Sedan
$49,100
MSRP $49,850
- Exterior color: IncognitoIncognito
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (314 mi away)4.99 out of 5 stars(174)
- Five Star Dealer
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Brookfield, WI / 314 miles away from Saint Charles, MO
SPRING SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E23S5040561
Stock: 28257
Listed since: 05-15-2025
2025 Lexus IS
350 F SPORT Sedan
$55,730
MSRP $56,480
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (314 mi away)4.99 out of 5 stars(174)
- Five Star Dealer
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Brookfield, WI / 314 miles away from Saint Charles, MO
SPRING SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27S5040374
Stock: 28198
Listed since: 04-30-2025
New Listing
Stock photo^**
2025 Lexus IS
350 F SPORT Sedan
$54,970
MSRP $54,970
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Wichita (373 mi away)
- AWD/4WD
- Back-up camera
- Bluetooth
- Keyless Entry/Start
- Upgraded Headlights
Close
Located in Wichita, KS / 373 miles away from Saint Charles, MO
Scores 26 Highway MPG and 19 City MPG! This Lexus IS delivers a 3.5L V6 DOHC Dual VVT-i 24V engine powering this Automatic transmission. Front And Rea...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E20S5040605
Stock: 54L1285N
Listed since: 05-20-2025

Showing 1 - 21 out of 925 listings

IS Reviews & Specs

Consumer Reviews for the Lexus IS

Read recent reviews for the Lexus IS

Overall Consumer Rating

4.4 13 Reviews

Write a vehicle review See all 13 reviews

5 star
(77%)
4 star
(8%)
3 star
(0%)
2 star
(8%)
1 star
(8%)

The last of the V8's

HJP, 01/10/2024

2024 Lexus IS 500 F SPORT Performance Premium 4dr Sedan (5.0L 8cyl 8A)

Just purchased a 2024 IS500 vector blue as soon as I saw it at the dealer. Happy to pay MSRP as this will be a classic. The car is fast and fun to drive and unlike a hard core M3 or AMG it is actually very comfortable as a daily driver, and that V8 sound is SPECTACULAR! This is probably the best looking sports sedan in the market. Some reviews complain about a dated interior, however I …

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Trim	MPG	Engine	Starting Price
2025 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A)	19 - 26	6-cylinders (gas)	$53,688
2025 Lexus IS 350 F SPORT Design 4dr Sedan AWD (3.5L 6cyl 6A)	19 - 26	6-cylinders (gas)	$49,850
2025 Lexus IS 350 F SPORT Design 4dr Sedan (3.5L 6cyl 8A)	20 - 28	6-cylinders (gas)	$48,778

More about the Lexus IS

Edmunds has 925 New Lexus ISes for sale near you, including a 2025 IS 350 F SPORT Design Sedan and a 2025 IS 350 F SPORT Sedan ranging in price from $48,778 to $61,880.

How much is a new 2025 Lexus IS in Saint Charles, MO?: A new 2025 Lexus IS starts at $48,778 (including destination charge) in Saint Charles, MO. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus IS Sedan cost in Saint Charles, MO?: A new 2025 Lexus IS Sedan starts at $48,778 in Saint Charles, MO. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.

How much is a brand-new Lexus IS in Saint Charles, MO?: A brand-new Lexus IS starts at $48,778 in Saint Charles, MO. The price can change based on a number of factors such as location, model year, trim level and options.
How much does a 2025 Lexus IS cost in Saint Charles, MO?: A 2025 Lexus IS costs from $48,778 to about $61,880 in Saint Charles, MO. The prices will vary based on trim level, installed options and dealership discounts.

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