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925 listings
- Arriving Soon$53,923MSRP $53,923
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (17 mi away)(8)
- Home delivery*
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Located in Manchester, MO / 17 miles away from O Fallon, MO
Infrared 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V 19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21S5040418
Stock: 35244
Listed since: 03-29-2025 - New Listing$53,688MSRP $53,688
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Reliable Lexus (174 mi away)
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Located in Springfield, MO / 174 miles away from O Fallon, MO
Recent Arrival! 2025 Incognito Lexus IS 4D Sedan 350 F SPORT 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD 19/26 City/Highway MPG 19/26 City/Highw...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29S5038626
Stock: S5038626
Listed since: 05-15-2025 - Arriving Soon$54,883MSRP $54,883
- Exterior color: InfraredInfrared
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Reliable Lexus (174 mi away)
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Located in Springfield, MO / 174 miles away from O Fallon, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29S5040599
Stock: 040599
Listed since: 05-06-2025 - Arriving Soon$54,384MSRP $54,384
- Exterior color: IridiumIridium
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Reliable Lexus (174 mi away)
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Located in Springfield, MO / 174 miles away from O Fallon, MO
Recent Arrival! 2025 Iridium Lexus IS 4D Sedan 350 F SPORT 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD 19/26 City/Highway MPG 19/26 City/Highway...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28S5040139
Stock: S5040139
Listed since: 04-08-2025 - New Listing$50,428MSRP
- Exterior color: CaviarCaviar
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Orland (249 mi away)(2)
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Located in Orland Park, IL / 249 miles away from O Fallon, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E25S5040724
Stock: LX0716
Listed since: 05-16-2025 - New Listing$50,428MSRP
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Orland (249 mi away)(2)
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Located in Orland Park, IL / 249 miles away from O Fallon, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E23S5040706
Stock: LX0712
Listed since: 05-15-2025 - New Listing$57,178MSRP
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Orland (249 mi away)(2)
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Located in Orland Park, IL / 249 miles away from O Fallon, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27S5040648
Stock: LX0707
Listed since: 05-14-2025 - $55,450MSRP
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Merrillville (257 mi away)(3)
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Located in Merrillville, IN / 257 miles away from O Fallon, MO
0223 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VRecent Arrival! 19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XS5040630
Stock: LM0435
Listed since: 05-05-2025 - $52,998MSRP $52,998
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Woodfield Lexus (267 mi away)(35)
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Located in Schaumburg, IL / 267 miles away from O Fallon, MO
F SPORT DESIGN PACKAGE|-INC: STD EQUIP.|ACCESSORY PACKAGE|CARGO NET|REAR BUMPER APPLIQUE|KEY GLOVES|CARPET TRUNK MAT|WHEEL LOCKS|NAVIGATION PACKAGE|PR...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E23S5040642
Stock: 250907
Listed since: 05-02-2025 - Arriving Soon$58,198MSRP $58,198
- Exterior color: InfraredInfrared
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- McGrath Lexus of Chicago (271 mi away)
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Located in Chicago, IL / 271 miles away from O Fallon, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XS5040580
Stock: S1111
Listed since: 05-16-2025 - $48,778MSRP $48,778
- Exterior color: IridiumIridium
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Arlington (274 mi away)(2)
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Located in Arlington Heights, IL / 274 miles away from O Fallon, MO
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B21S5083719
Stock: AL3429
Listed since: 02-11-2025 - Arriving Soon$50,098MSRP $50,098
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (274 mi away)(2)
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Located in Arlington Heights, IL / 274 miles away from O Fallon, MO
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E21S5040638
Stock: AL3813
Listed since: 05-01-2025 - $50,630MSRP $50,630
- Exterior color: InfraredInfrared
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (274 mi away)(2)
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Located in Arlington Heights, IL / 274 miles away from O Fallon, MO
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E23S5040768
Stock: 3448
Listed since: 05-08-2025 - $50,535MSRP $50,535
- Exterior color: IridiumIridium
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (274 mi away)(2)
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Located in Arlington Heights, IL / 274 miles away from O Fallon, MO
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E20S5040825
Stock: 3442
Listed since: 05-14-2025 - $54,988MSRP $54,988
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Highland Park (282 mi away)
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Located in Highland Park, IL / 282 miles away from O Fallon, MO
Infra Red 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V19/26 City/Highway MPGLexus of Highland Park is a truly fami...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28S5040626
Stock: 250632
Listed since: 05-01-2025 - $61,880MSRP $61,880
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Lexus of Highland Park (282 mi away)
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Located in Highland Park, IL / 282 miles away from O Fallon, MO
Gray 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V19/26 City/Highway MPGLexus of Highland Park is a truly family-ow...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XS5040319
Stock: 250605
Listed since: 04-22-2025 - Arriving Soon$58,420MSRP $59,170
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (324 mi away)(174)
- Five Star Dealer
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Located in Brookfield, WI / 324 miles away from O Fallon, MO
SPRING SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27S5040598
Stock: 040598
Listed since: 05-01-2025 - $49,445MSRP $50,195
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (324 mi away)(174)
- Five Star Dealer
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Located in Brookfield, WI / 324 miles away from O Fallon, MO
SPRING SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E28S5039907
Stock: 28088
Listed since: 04-07-2025 - New Listing$49,100MSRP $49,850
- Exterior color: IncognitoIncognito
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (324 mi away)(174)
- Five Star Dealer
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Located in Brookfield, WI / 324 miles away from O Fallon, MO
SPRING SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E23S5040561
Stock: 28257
Listed since: 05-15-2025 - $55,730MSRP $56,480
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (324 mi away)(174)
- Five Star Dealer
Close
Located in Brookfield, WI / 324 miles away from O Fallon, MO
SPRING SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27S5040374
Stock: 28198
Listed since: 04-30-2025 - New Listing$54,970MSRP $54,970
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Wichita (359 mi away)
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Located in Wichita, KS / 359 miles away from O Fallon, MO
Scores 26 Highway MPG and 19 City MPG! This Lexus IS delivers a 3.5L V6 DOHC Dual VVT-i 24V engine powering this Automatic transmission. Front And Rea...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E20S5040605
Stock: 54L1285N
Listed since: 05-20-2025
Showing 1 - 21 out of 925 listings
Consumer Reviews for the Lexus IS
Read recent reviews for the Lexus IS
The last of the V8's
HJP, 01/10/2024
2024 Lexus IS 500 F SPORT Performance Premium 4dr Sedan (5.0L 8cyl 8A)
Just purchased a 2024 IS500 vector blue as soon as I saw it at the dealer. Happy to pay MSRP as this will be a classic. The car is fast and fun to drive and unlike a hard core M3 or AMG it is actually very comfortable as a daily driver, and that V8 sound is SPECTACULAR! This is probably the best looking sports sedan in the market. Some reviews complain about a dated interior, however I … find it comfortable and very high quality, in fact that is one of the reasons Lexus and Toyotas are so reliable, they are not constantly making drastic changes every year but constantly improving on what is already a top notch fit and finish. If you live in an area with winter snow and ice this might not be a good year round car and the only other possible issue is the rear seat is tight so if you transport big and tall people keep the ride short.
| Trim | MPG | Engine | Starting Price |
|---|---|---|---|
| 2025 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $53,688 |
| 2025 Lexus IS 350 F SPORT Design 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $49,850 |
| 2025 Lexus IS 350 F SPORT Design 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $48,778 |
More about the Lexus IS
Edmunds has 925 New Lexus ISes for sale near you, including a 2025 IS 350 F SPORT Design Sedan and a 2025 IS 350 F SPORT Sedan ranging in price from $48,778 to $61,880.
How much is a new 2025 Lexus IS in O Fallon, MO?
- A new 2025 Lexus IS starts at $48,778 (including destination charge) in O Fallon, MO. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus IS Sedan cost in O Fallon, MO?
- A new 2025 Lexus IS Sedan starts at $48,778 in O Fallon, MO. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
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