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925 listings
- $45,578MSRP $45,578
- Exterior color: IridiumIridium
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 21 City / 31 Hwy MPG
- Flow Lexus of Winston Salem (599 mi away)
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Located in Winston Salem, NC / 599 miles away from O Fallon, MO
This Lexus won't be on the lot long! Both practical and stylish! A turbocharger further enhances performance, while also preserving fuel economy. All ...
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHCA1D29S5134070
Stock: 38609
Listed since: 02-17-2025 - $47,288MSRP $47,288
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Flow Lexus of Winston Salem (599 mi away)
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Located in Winston Salem, NC / 599 miles away from O Fallon, MO
The car you've always wanted! Don't miss this great Lexus! Both practical and stylish! Lexus prioritized handling and performance with features such a...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B29S5086965
Stock: 38951
Listed since: 05-12-2025 - Arriving Soon$51,448MSRP $51,448
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Flow Lexus of Winston Salem (599 mi away)
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Located in Winston Salem, NC / 599 miles away from O Fallon, MO
This vehicle won't be on the lot long! Assembled with the most discerning driver in mind. Lexus infused the interior with top shelf amenities, such as...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B24S5087267
Stock: 38911
Listed since: 05-06-2025 - $52,463MSRP $52,463
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Flow Lexus of Greensboro (624 mi away)
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Located in Greensboro, NC / 624 miles away from O Fallon, MO
This vehicle won't be on the lot long! Feature-packed and decked out! Lexus prioritized practicality, efficiency, and style by including: speed sensit...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B24S5086989
Stock: 6488
Listed since: 04-24-2025 - $47,174MSRP $47,174
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 21 City / 31 Hwy MPG
- Flow Lexus of Greensboro (624 mi away)
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Located in Greensboro, NC / 624 miles away from O Fallon, MO
Here is the opportunity you've been waiting for! You won't want to miss this excellent value! Packed with features and truly a pleasure to drive! Turb...
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D23S5133338
Stock: 6035
Listed since: 12-16-2024 - $46,094MSRP $46,094
- Exterior color: CaviarCaviar
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 20 City / 28 Hwy MPG
- Flow Lexus of Greensboro (624 mi away)
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Located in Greensboro, NC / 624 miles away from O Fallon, MO
If you've been looking for just the right vehicle, then stop your search right here. This Lexus won't be on the lot long! It delivers style and power ...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B29S5086755
Stock: 6478
Listed since: 04-22-2025 - $48,985MSRP $48,985
- Exterior color: Ultra WhiteUltra White
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 20 City / 28 Hwy MPG
- Flow Lexus of Greensboro (624 mi away)
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Located in Greensboro, NC / 624 miles away from O Fallon, MO
How about this great vehicle! From front to rear, this model exhibits grace and agility. Lexus infused the interior with top shelf amenities, such as:...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B22S5086869
Stock: 6487
Listed since: 04-24-2025 - $47,313MSRP $47,313
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Black leatheretteBlack leatherette
- 21 City / 31 Hwy MPG
- Flow Lexus of Greensboro (624 mi away)
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Located in Greensboro, NC / 624 miles away from O Fallon, MO
This vehicle won't be on the lot long! Luxury, power and finesse propel this vehicle ahead of the pack. The engine breathes better thanks to a turboch...
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D27S5134671
Stock: 6512
Listed since: 04-28-2025 - Arriving Soon$45,218MSRP $45,218
- Exterior color: Matador Red MicaMatador Red Mica
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 21 City / 31 Hwy MPG
- Flow Lexus of Greensboro (624 mi away)
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Located in Greensboro, NC / 624 miles away from O Fallon, MO
This Lexus won't be on the lot long! It comes equipped with all the standard amenities for your driving enjoyment. A turbocharger is also included as ...
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHCA1D23S5134453
Stock: 134453
Listed since: 04-02-2025 - $49,630MSRP $47,188
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 21 City / 31 Hwy MPG
- Jim Hudson Lexus (629 mi away)(16)
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Located in Columbia, SC / 629 miles away from O Fallon, MO
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D24S5134756
Stock: C35537
Listed since: 04-05-2025 - $49,630MSRP $47,188
- Exterior color: IridiumIridium
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 21 City / 31 Hwy MPG
- Jim Hudson Lexus (629 mi away)(16)
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Located in Columbia, SC / 629 miles away from O Fallon, MO
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D2XS5134650
Stock: C35461
Listed since: 03-23-2025 - $49,630MSRP $47,188
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 21 City / 31 Hwy MPG
- Jim Hudson Lexus (629 mi away)(16)
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Located in Columbia, SC / 629 miles away from O Fallon, MO
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D2XS5134728
Stock: C35481
Listed since: 03-30-2025 - $54,480MSRP $52,038
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Jim Hudson Lexus (629 mi away)(16)
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Located in Columbia, SC / 629 miles away from O Fallon, MO
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22S5087512
Stock: C35538
Listed since: 04-15-2025 - $49,370MSRP $46,928
- Exterior color: Ultra WhiteUltra White
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 20 City / 28 Hwy MPG
- Jim Hudson Lexus (629 mi away)(16)
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Located in Columbia, SC / 629 miles away from O Fallon, MO
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B2XS5087817
Stock: C35583
Listed since: 04-27-2025 - $49,130MSRP $46,688
- Exterior color: CaviarCaviar
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 21 City / 31 Hwy MPG
- Jim Hudson Lexus (629 mi away)(16)
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Located in Columbia, SC / 629 miles away from O Fallon, MO
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D29S5134722
Stock: C35482
Listed since: 03-29-2025 - $48,807MSRP $46,365
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Jim Hudson Lexus (629 mi away)(16)
Close
Located in Columbia, SC / 629 miles away from O Fallon, MO
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B24S5086517
Stock: L35157
Listed since: 05-07-2025 - New Listing$49,370MSRP $46,928
- Exterior color: Ultra WhiteUltra White
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 20 City / 28 Hwy MPG
- Jim Hudson Lexus (629 mi away)(16)
Close
Located in Columbia, SC / 629 miles away from O Fallon, MO
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B29S5088134
Stock: C35618
Listed since: 05-18-2025 - $47,667MSRP $47,168
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 20 City / 28 Hwy MPG
- Johnson Lexus of Durham (675 mi away)
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Located in Durham, NC / 675 miles away from O Fallon, MO
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B21S5086507
Stock: D12334 - $47,667MSRP $47,168
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Johnson Lexus of Durham (675 mi away)
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Located in Durham, NC / 675 miles away from O Fallon, MO
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B23S5087125
Stock: D12341 - New Listing$53,057MSRP $52,558
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: White leatheretteWhite leatherette
- 20 City / 28 Hwy MPG
- Johnson Lexus of Durham (675 mi away)
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Located in Durham, NC / 675 miles away from O Fallon, MO
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B25S5087004
Stock: D12344T - $48,442MSRP $47,943
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 21 City / 31 Hwy MPG
- Johnson Lexus of Durham (675 mi away)
Close
Located in Durham, NC / 675 miles away from O Fallon, MO
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D22S5134478
Stock: D12326
Showing 64 - 84 out of 925 listings
Consumer Reviews for the Lexus IS
Read recent reviews for the Lexus IS
The last of the V8's
HJP, 01/10/2024
2024 Lexus IS 500 F SPORT Performance Premium 4dr Sedan (5.0L 8cyl 8A)
Just purchased a 2024 IS500 vector blue as soon as I saw it at the dealer. Happy to pay MSRP as this will be a classic. The car is fast and fun to drive and unlike a hard core M3 or AMG it is actually very comfortable as a daily driver, and that V8 sound is SPECTACULAR! This is probably the best looking sports sedan in the market. Some reviews complain about a dated interior, however I … find it comfortable and very high quality, in fact that is one of the reasons Lexus and Toyotas are so reliable, they are not constantly making drastic changes every year but constantly improving on what is already a top notch fit and finish. If you live in an area with winter snow and ice this might not be a good year round car and the only other possible issue is the rear seat is tight so if you transport big and tall people keep the ride short.
| Trim | MPG | Engine | Starting Price |
|---|---|---|---|
| 2025 Lexus IS 300 4dr Sedan (2.0L 4cyl Turbo 8A) | 21 - 31 | 4-cylinders (gas) | $45,218 |
| 2025 Lexus IS 350 F SPORT Design 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $46,094 |
| 2025 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $51,448 |
More about the Lexus IS
Edmunds has 925 New Lexus ISes for sale near you, including a 2025 IS 300 Sedan and a 2025 IS 350 F SPORT Sedan ranging in price from $45,218 to $52,558.
How much is a new 2025 Lexus IS in O Fallon, MO?
- A new 2025 Lexus IS starts at $45,218 (including destination charge) in O Fallon, MO. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus IS Sedan cost in O Fallon, MO?
- A new 2025 Lexus IS Sedan starts at $45,218 in O Fallon, MO. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
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