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    • Exterior color: Nightfall MicaNightfall Mica
    • Interior color: Macadamia leatherMacadamia leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Mica AWD Automatic 2.5L I4 DOHC 16VRecent Arrival! 37/34 City/Highway MPG2025 Lexus RX 350h Premium Plus

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA6SC102339
    Stock: 51587
    Listed since: 09-10-2025

    • Exterior color: CaviarCaviar
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Caviar AWD Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG2025 Lexus RX 350 Premium

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA6SC111691
    Stock: 51584
    Listed since: 09-09-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Pear AWD Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG2025 Lexus RX 350 Premium

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7SC121209
    Stock: 51579
    Listed since: 09-11-2025

    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Gray AWD Automatic 2.4L I4 Turbo21/28 City/Highway MPG2025 Lexus RX 350 Premium

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA5SC117353
    Stock: 51424
    Listed since: 08-13-2025

    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Black premium leatherBlack premium leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Gray AWD Automatic 2.4L I4 Turbo21/28 City/Highway MPG2025 Lexus RX 350 Luxury

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA9SC119946
    Stock: 51548
    Listed since: 09-03-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Pear AWD Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG2025 Lexus RX 350 Premium

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7SC120660
    Stock: 51557
    Listed since: 09-08-2025

    • Exterior color: Copper CrestCopper Crest
    • Interior color: Black premium leatherBlack premium leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Copper AWD Automatic 2.4L I4 Turbo21/28 City/Highway MPG2025 Lexus RX 350 Luxury

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA6SC119435
    Stock: 51525
    Listed since: 08-30-2025

    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Mica AWD Automatic 2.4L I4 Turbo21/28 City/Highway MPG2025 Lexus RX 350 Premium

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA6SC116700
    Stock: 51611
    Listed since: 08-28-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Pear AWD Automatic 2.4L I4 Turbo21/28 City/Highway MPG2025 Lexus RX 350 Premium

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCAXSC120331
    Stock: 51549
    Listed since: 09-04-2025

    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Palomino leatherPalomino leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Matador Red Mica AWD Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG2025 Lexus RX 350 Premium Plus

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA1SC119391
    Stock: 51612
    Listed since: 09-09-2025

    • Exterior color: CaviarCaviar
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Caviar AWD Automatic 2.4L I4 Turbo21/28 City/Highway MPG2025 Lexus RX 350 Premium

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA5SC108815
    Stock: 51173
    Listed since: 06-14-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black premium leatherBlack premium leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Pear AWD Automatic 2.5L I4 DOHC 16V37/34 City/Highway MPG2025 Lexus RX 350h Luxury

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA5SC101294
    Stock: 51554
    Listed since: 09-05-2025

    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Gray AWD Automatic 2.4L I4 Turbo21/28 City/Highway MPG2025 Lexus RX 350 Premium

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC119201
    Stock: 51512
    Listed since: 08-22-2025

    • Exterior color: Nightfall MicaNightfall Mica
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Mica AWD Automatic 2.4L I4 Turbo21/28 City/Highway MPG2025 Lexus RX 350 Premium

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA9SC120336
    Stock: 51550
    Listed since: 09-04-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Pear AWD Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG2025 Lexus RX 350 Premium

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC121109
    Stock: 51600
    Listed since: 09-15-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black premium leatherBlack premium leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Pear AWD Automatic 2.5L I4 DOHC 16VRecent Arrival! 37/34 City/Highway MPG2025 Lexus RX 350h Luxury

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA6SC102695
    Stock: 51616
    Listed since: 09-19-2025

    • Exterior color: IridiumIridium
    • Interior color: Rioja Red leatherRioja Red leather
    • 5 Seats, 27 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Iridium AWD Automatic 2.4L I4 PDI Hybrid Turbocharged DOHC 16V LEV3-SULEV30 274hpRecent Arrival! 27/28 City/Highway MPG2025 Lexus RX 500h F SPORT Perf...

    Features and Specs:

    27 Combined MPG (27 City/28 Highway)

    Listing Information:

    VIN: 2T2BCMEA1SC022750
    Stock: 51613
    Listed since: 09-15-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Birch leatherBirch leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Easton (576 mi away)4.95 out of 5 stars(21)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbus, OH / 576 miles away from West Des Moines, IA

    Pear AWD Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG2025 Lexus RX 350 Premium Plus

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCAXSC121141
    Stock: 51580
    Listed since: 09-11-2025

  • Stock photo**
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Lexus of Greenwood Village (600 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Greenwood Village, CO / 600 miles away from West Des Moines, IA

    Pear 2025 Lexus RX 350 Premium FWD 8-Speed Automatic 2.4L I4 TurboEach L/Certified by Lexus vehicle undergoes a comprehensive inspection including: ...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: JTJCHMAA7S2031139
    Stock: S2031139
    Listed since: 09-04-2025

  • Stock photo**
    • Exterior color: CaviarCaviar
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Lexus of Greenwood Village (600 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Greenwood Village, CO / 600 miles away from West Des Moines, IA

    Caviar 2025 Lexus RX 350 Premium FWD 8-Speed Automatic 2.4L I4 TurboEach L/Certified by Lexus vehicle undergoes a comprehensive inspection including...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: JTJCHMAA0S2031144
    Stock: S2031144
    Listed since: 09-03-2025

  • Stock photo**
    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Macadamia leatherMacadamia leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Greenwood Village (600 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Greenwood Village, CO / 600 miles away from West Des Moines, IA

    Matador Red Mica 2025 Lexus RX 350h Premium Plus AWD CVT 2.5L I4 DOHC 16VEach L/Certified by Lexus vehicle undergoes a comprehensive inspection incl...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA2SC100149
    Stock: SC100149
    Listed since: 09-09-2025

Showing 400 - 420 out of 3,757 listings
TrimMPGEngineStarting Price
2025 Lexus RX 350h Premium Plus 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$61,995
2025 Lexus RX 350 Premium 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$58,424
2025 Lexus RX 350 Luxury 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$67,015
2025 Lexus RX 350 Premium Plus 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$61,270
2025 Lexus RX 350h Luxury 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$69,769
2025 Lexus RX 500h F SPORT Performance 4dr SUV AWD (2.4L 4cyl Turbo gas/electric hybrid 6A)27 - 284-cylinders (hybrid)$73,000
2025 Lexus RX 350 Premium 4dr SUV (2.4L 4cyl Turbo 8A)22 - 294-cylinders (gas)$55,954

More about the Lexus RX

Edmunds has 3,757 New Lexus RXes for sale near you, including a 2025 RX 350 Premium SUV and a 2025 RX 500h F SPORT Performance SUV ranging in price from $55,954 to $73,000.

How much is a new 2025 Lexus RX in West Des Moines, IA?

A new 2025 Lexus RX starts at $55,954 (including destination charge) in West Des Moines, IA. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Lexus RX Hybrid cost in West Des Moines, IA?

A new 2025 Lexus RX Hybrid starts at $61,995 in West Des Moines, IA. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Lexus RX SUV which starts at $55,954.
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