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  • Stock photo**
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wichita (324 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wichita, KS / 324 miles away from West Des Moines, IA

    Delivers 28 Highway MPG and 21 City MPG! This Lexus RX boasts a 2.4L I4 Turbo engine powering this Automatic transmission. Front And Rear Anti-Roll Ba...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA4SC120793
    Stock: 54L1516N
    Listed since: 09-22-2025

    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Black leatherBlack leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wichita (324 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wichita, KS / 324 miles away from West Des Moines, IA

    Boasts 28 Highway MPG and 21 City MPG! This Lexus RX boasts a 2.4L I4 Turbo engine powering this Automatic transmission. Front And Rear Anti-Roll Bars...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7SC115460
    Stock: 54L1540N
    Listed since: 09-22-2025

  • New Listing
    Stock photo**
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Palomino leatherPalomino leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wichita (324 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wichita, KS / 324 miles away from West Des Moines, IA

    Boasts 28 Highway MPG and 21 City MPG! This Lexus RX delivers a 2.4L I4 Turbo engine powering this Automatic transmission. Front And Rear Anti-Roll Ba...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC120011
    Stock: 54L1588N
    Listed since: 09-16-2025

  • Stock photo**
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wichita (324 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Wichita, KS / 324 miles away from West Des Moines, IA

    Boasts 28 Highway MPG and 21 City MPG! This Lexus RX boasts a 2.4L I4 Turbo engine powering this Automatic transmission. Front And Rear Anti-Roll Bars...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCAXSC119924
    Stock: 54L1587N
    Listed since: 09-14-2025

  • New Listing
    Stock photo**
    • Exterior color: Nightfall MicaNightfall Mica
    • Interior color: Palomino leatherPalomino leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Wichita (324 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wichita, KS / 324 miles away from West Des Moines, IA

    Delivers 34 Highway MPG and 37 City MPG! This Lexus RX boasts a 2.5L I4 DOHC 16V engine powering this Variable transmission. Front And Rear Anti-Roll ...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA7SC101068
    Stock: 54L1590N
    Listed since: 09-16-2025

  • Stock photo**
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Macadamia premium leatherMacadamia premium leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Wichita (324 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Wichita, KS / 324 miles away from West Des Moines, IA

    Boasts 28 Highway MPG and 21 City MPG! This Lexus RX delivers a 2.4L I4 Turbo engine powering this Automatic transmission. Front And Rear Anti-Roll Ba...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7SC120657
    Stock: 54L1598N
    Listed since: 09-19-2025

    • Exterior color: CaviarCaviar
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    0223 2025 Lexus RX 350 Premium AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA1SC120511
    Stock: LM0670
    Listed since: 09-10-2025

  • New Listing
    Stock photo**
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatherBlack leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    0085 2025 Lexus RX 350h Premium Plus AWD CVT 2.5L I4 DOHC 16VRecent Arrival! 37/34 City/Highway MPG

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA1SC103172
    Stock: LM0697
    Listed since: 09-19-2025

    • Exterior color: CaviarCaviar
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    0223 2025 Lexus RX 350 Premium AWD 8-Speed Automatic 2.4L I4 Turbo21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7SC113689
    Stock: LM0560
    Listed since: 07-12-2025

  • New Listing
    Stock photo**
    • Exterior color: Copper CrestCopper Crest
    • Interior color: Black leatherBlack leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    04y5 2025 Lexus RX 350 Premium Plus AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA1SC122534
    Stock: LM0692
    Listed since: 09-19-2025

  • Arriving Soon
    Stock photo**
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Birch leatherBirch leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    0085 2025 Lexus RX AWD CVT 2.5L I4 DOHC 16VRecent Arrival! 37/34 City/Highway MPG

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA9SC103243
    Stock: LX1119
    Listed since: 09-18-2025

  • New Listing
    Stock photo**
    • Exterior color: IridiumIridium
    • Interior color: Palomino leatherPalomino leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    01l2 2025 Lexus RX 350 Premium Plus AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA0SC122220
    Stock: LM0689
    Listed since: 09-17-2025

    • Exterior color: IridiumIridium
    • Interior color: Black premium leatherBlack premium leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    01l2 2025 Lexus RX 350 Luxury AWD 8-Speed Automatic 2.4L I4 Turbo21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC118959
    Stock: LM0655
    Listed since: 08-27-2025

  • Stock photo**
    • Exterior color: IridiumIridium
    • Interior color: Macadamia premium leatherMacadamia premium leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    01l2 2025 Lexus RX 350 Luxury AWD 8-Speed Automatic 2.4L I4 Turbo21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC116962
    Stock: LM0619
    Listed since: 08-14-2025

  • Stock photo**
    • Exterior color: Copper CrestCopper Crest
    • Interior color: Macadamia leatherMacadamia leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    04y5 2025 Lexus RX AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC122073
    Stock: LM0685
    Listed since: 09-18-2025

  • Stock photo**
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    0085 2025 Lexus RX 350 Premium AWD 8-Speed Automatic 2.4L I4 TurboRecent Arrival! 21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC120761
    Stock: LM0674
    Listed since: 09-10-2025

  • New Listing
    Stock photo**
    • Exterior color: Copper CrestCopper Crest
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    04y5 2025 Lexus RX 350h Premium AWD CVT 2.5L I4 DOHC 16VRecent Arrival! 37/34 City/Highway MPG

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA6SC103474
    Stock: LM0698
    Listed since: 09-20-2025

    • Exterior color: CaviarCaviar
    • Interior color: Black leatherBlack leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    0223 2025 Lexus RX AWD CVT 2.5L I4 DOHC 16V37/34 City/Highway MPG

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA3SC100905
    Stock: LM0665
    Listed since: 09-05-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    0085 2025 Lexus RX 350 Premium AWD 8-Speed Automatic 2.4L I4 Turbo21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA5SC114789
    Stock: LM0597
    Listed since: 07-30-2025

    • Exterior color: Copper CrestCopper Crest
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    04y5 2025 Lexus RX 350 Premium AWD 8-Speed Automatic 2.4L I4 Turbo21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC118721
    Stock: LM0654
    Listed since: 08-27-2025

  • New Listing
    Stock photo**
    • Exterior color: CaviarCaviar
    • Interior color: Black premium leatherBlack premium leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Merrillville (330 mi away)5 out of 5 stars(2)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Merrillville, IN / 330 miles away from West Des Moines, IA

    0223 2025 Lexus RX 350h Luxury AWD CVT 2.5L I4 DOHC 16VRecent Arrival! 37/34 City/Highway MPG

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA7SC103242
    Stock: LM0694
    Listed since: 09-19-2025

Showing 337 - 357 out of 3,778 listings
TrimMPGEngineStarting Price
2025 Lexus RX 350 Premium 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$57,600
2025 Lexus RX 350 Premium Plus 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$61,610
2025 Lexus RX 350h Premium Plus 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$62,714
2025 Lexus RX 350 Luxury 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$67,535
2025 Lexus RX 350h Premium 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$58,954
2025 Lexus RX 350h Luxury 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$68,639

More about the Lexus RX

Edmunds has 3,778 New Lexus RXes for sale near you, including a 2025 RX 350 Premium SUV and a 2025 RX 350h Luxury SUV ranging in price from $57,600 to $68,639.

How much is a new 2025 Lexus RX in West Des Moines, IA?

A new 2025 Lexus RX starts at $57,600 (including destination charge) in West Des Moines, IA. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Lexus RX SUV cost in West Des Moines, IA?

A new 2025 Lexus RX SUV starts at $57,600 in West Des Moines, IA. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
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