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  • Arriving Soon
    Photos not available
    $59,244
    MSRP $59,244
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Lexus of Fort Myers (672 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Fort Myers, FL / 672 miles away from Natchez, MS

    Navigation, Sunroof, Heated Leather Seats, Rear Air, Turbo Charged, Alloy Wheels, ACCESSORY PACKAGE (Z1), Power Liftgate. FUEL EFFICIENT 29 MPG Hwy/22...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: JTJCHMAA9S2033118
    Stock: S2033118
    Listed since: 09-19-2025

  • Stock photo**
    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Black leatherBlack leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Lexus of Fort Myers (672 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Fort Myers, FL / 672 miles away from Natchez, MS

    Navigation, Sunroof, Heated Leather Seats, Rear Air, All Wheel Drive, Turbo Charged, Alloy Wheels, TECHNOLOGY PACKAGE, CONVENIENCE PACKAGE. FUEL EFFIC...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCAXSC118711
    Stock: SC118711
    Listed since: 09-03-2025

  • Arriving Soon
    Stock photo**
    $58,649
    MSRP $58,649
    • Exterior color: Matador Red MicaMatador Red Mica
    • 5 Seats, 22 City / 29 Hwy MPG
    • Lexus of Fort Myers (672 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Fort Myers, FL / 672 miles away from Natchez, MS

    Nav System, Moonroof, Heated Leather Seats, Rear Air, Turbo Charged Engine, Aluminum Wheels, ACCESSORY PACKAGE (Z1), Power Liftgate. Matador Red Mica ...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: JTJCHMAA0S2032956
    Stock: S2032956
    Listed since: 09-19-2025

  • New Listing
    Stock photo**
    • Exterior color: Nightfall MicaNightfall Mica
    • Interior color: Birch leatherBirch leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Lexus of Fort Myers (672 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Fort Myers, FL / 672 miles away from Natchez, MS

    Heated Leather Seats, NAV, Sunroof, Rear Air, All Wheel Drive, Alloy Wheels, ACCESSORY PACKAGE (Z1), TECHNOLOGY PACKAGE, PANORAMA GLASS ROOF, CONVENIE...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA7SC101782
    Stock: SC101782
    Listed since: 09-18-2025

  • Arriving Soon
    Stock photo**
    $56,764
    MSRP $56,764
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Lexus of Fort Myers (672 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Fort Myers, FL / 672 miles away from Natchez, MS

    Heated/Cooled Seats, Navigation, Sunroof, Rear Air, Turbo Charged, Alloy Wheels, RADIO: LEXUS INTERFACE W/14 HD TOUCHSCREEN DISPLAY, ACCESSORY PACKAGE...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: JTJCHMAA1S2033002
    Stock: S2033002
    Listed since: 09-18-2025

  • Stock photo**
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Lexus of Fort Myers (672 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Fort Myers, FL / 672 miles away from Natchez, MS

    Heated/Cooled Seats, Navigation, Moonroof, Rear Air, Turbo Charged, Aluminum Wheels, RADIO: LEXUS INTERFACE W/14 HD TOUCHSCREEN DISPLAY, ACCESSORY PAC...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: JTJCHMAA3S2032269
    Stock: S2032269
    Listed since: 09-06-2025

  • New Listing
    Stock photo**
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Black premium leatherBlack premium leather
    • 5 Seats
    • Lexus of Fort Myers (672 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Fort Myers, FL / 672 miles away from Natchez, MS

    Heated Leather Seats, NAV, Sunroof, Power Liftgate, Panoramic Roof, Turbo, Alloy Wheels, ACCESSORY PACKAGE (Z1), TECHNOLOGY PACKAGE, ADVANCED PARK, RA...

    Features and Specs:

    Listing Information:

    VIN: JTJCJMGA1S2035098
    Stock: S2035098
    Listed since: 09-15-2025

  • Stock photo**
    $51,410
    MSRP $51,410
    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Lexus of Fort Myers (672 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Fort Myers, FL / 672 miles away from Natchez, MS

    Nav System, Heated Seats, Back-Up Camera, Power Liftgate, Turbo Charged Engine, Aluminum Wheels, TECHNOLOGY PACKAGE, Rear Air. Matador Red Mica exteri...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA5SC067975
    Stock: SC067975
    Listed since: 09-11-2025

  • Stock photo**
    $51,015
    MSRP $51,015
    • Exterior color: CaviarCaviar
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Caviar 2025 Lexus RX 350 FWD 8-Speed Automatic 2.4L I4 Turbo Palomino Nuluxe Artificial Leather. 22/29 City/Highway MPG

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA2SC067657
    Stock: L251674
    Listed since: 09-01-2025

  • New Listing
    Stock photo**
    • Exterior color: CaviarCaviar
    • Interior color: Black premium leatherBlack premium leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Caviar 2025 Lexus RX 350h Luxury AWD CVT 2.5L I4 DOHC 16V 2.5L I4 DOHC 16V, AWD, Black Semi Anil Leather. Recent Arrival! 37/34 City/Highway MPG

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCAXSC101405
    Stock: L251738
    Listed since: 09-15-2025

  • Arriving Soon
    Stock photo**
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Gray 2025 Lexus RX 350h Premium AWD CVT 2.5L I4 DOHC 16V 2.5L I4 DOHC 16V, AWD, Birch Nuluxe Artificial Leather. Recent Arrival! 37/34 City/Highway MP...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA8SC099959
    Stock: L251751
    Listed since: 09-08-2025

  • New Listing
    Stock photo**
    • Exterior color: Ultra WhiteUltra White
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Ultra White 2025 Lexus RX 350 F Sport AWD 8-Speed Automatic 2.4L I4 Turbo AWD, Birch Nuluxe Artificial Leather. Recent Arrival! 21/28 City/Highway MPG

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA6SC120391
    Stock: L251735
    Listed since: 09-15-2025

  • Stock photo**
    • Exterior color: Nori Green PearlNori Green Pearl
    • Interior color: Birch leatherBirch leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Green Pearl 2025 Lexus RX 350h Premium Plus AWD CVT 2.5L I4 DOHC 16V 2.5L I4 DOHC 16V, AWD, Birch Leather. Recent Arrival! 37/34 City/Highway MPG

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA6SC100655
    Stock: L251707
    Listed since: 09-09-2025

  • New Listing
    Stock photo**
    • Exterior color: IridiumIridium
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Iridium 2025 Lexus RX 350h Premium AWD CVT 2.5L I4 DOHC 16V 2.5L I4 DOHC 16V, AWD, Palomino Nuluxe Artificial Leather. Recent Arrival! 37/34 City/High...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA2SC101690
    Stock: L251747
    Listed since: 09-17-2025

  • Stock photo**
    $51,015
    MSRP $51,015
    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Matador Red Mica 2025 Lexus RX 350 FWD 8-Speed Automatic 2.4L I4 Turbo Black Nuluxe Artificial Leather. 22/29 City/Highway MPG

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA1SC067682
    Stock: L251677
    Listed since: 09-03-2025

  • Arriving Soon
    Stock photo**
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatherBlack leather
    • 5 Seats, 22 City / 29 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Pear 2025 Lexus RX 350 Premium Plus FWD 8-Speed Automatic 2.4L I4 Turbo Black Leather. 22/29 City/Highway MPG

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: JTJCHMAA4S2031289
    Stock: L251640
    Listed since: 08-21-2025

  • New Listing
    Stock photo**
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Gray 2025 Lexus RX 350h AWD CVT 2.5L I4 DOHC 16V 2.5L I4 DOHC 16V, AWD, Birch Nuluxe Artificial Leather. Recent Arrival! 37/34 City/Highway MPG

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA5SC101795
    Stock: L251749
    Listed since: 09-17-2025

  • Arriving Soon
    Stock photo**
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Gray 2025 Lexus RX 350 Premium FWD 8-Speed Automatic 2.4L I4 Turbo Palomino Nuluxe Artificial Leather. Recent Arrival! 22/29 City/Highway MPG

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: JTJCHMAA1S2032786
    Stock: L251722
    Listed since: 09-08-2025

  • Arriving Soon
    Stock photo**
    $51,364
    MSRP $51,364
    • Exterior color: Nightfall MicaNightfall Mica
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Mica 2025 Lexus RX 350 FWD 8-Speed Automatic 2.4L I4 Turbo Palomino Nuluxe Artificial Leather. Recent Arrival! 22/29 City/Highway MPG

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA9SC068188
    Stock: L251739
    Listed since: 09-16-2025

  • Arriving Soon
    Stock photo**
    • Exterior color: Nori Green PearlNori Green Pearl
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Green Pearl 2025 Lexus RX 350 Premium FWD 8-Speed Automatic 2.4L I4 Turbo Black Nuluxe Artificial Leather. Recent Arrival! 22/29 City/Highway MPG

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA8SC067775
    Stock: L251687
    Listed since: 09-04-2025

  • Arriving Soon
    Stock photo**
    • Exterior color: Nori Green PearlNori Green Pearl
    • Interior color: Palomino leatherettePalomino leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Germain Lexus of Naples (685 mi away)4.97 out of 5 stars(74)
    • Five Star Dealer
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Naples, FL / 685 miles away from Natchez, MS

    Green Pearl 2025 Lexus RX 350h Premium AWD CVT 2.5L I4 DOHC 16V 2.5L I4 DOHC 16V, AWD, Palomino Nuluxe Artificial Leather. Recent Arrival! 37/34 City/...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA6SC101076
    Stock: L251724
    Listed since: 09-12-2025

Showing 610 - 630 out of 3,527 listings
TrimMPGEngineStarting Price
2025 Lexus RX 350 4dr SUV (2.4L 4cyl Turbo 8A)22 - 294-cylinders (gas)$51,015
2025 Lexus RX 350 Premium Plus 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$61,110
2025 Lexus RX 350h Premium Plus 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$62,310
2025 Lexus RX 350 Premium 4dr SUV (2.4L 4cyl Turbo 8A)22 - 294-cylinders (gas)$56,854
2025 Lexus RX 450h+ Luxury 4dr SUV AWD (2.5L 4cyl gas/electric plug-in hybrid CVT)N/A4-cylinders (plug-in hybrid)$78,174
2025 Lexus RX 350h Luxury 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$69,213
2025 Lexus RX 350h Premium 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$57,963
2025 Lexus RX 350 F SPORT Design 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$61,404
2025 Lexus RX 350h 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$58,463
2025 Lexus RX 350 Premium Plus 4dr SUV (2.4L 4cyl Turbo 8A)22 - 294-cylinders (gas)$59,239

More about the Lexus RX

Edmunds has 3,527 New Lexus RXes for sale near you, including a 2025 RX 350 SUV and a 2025 RX 450h+ Luxury SUV ranging in price from $51,015 to $78,174.

How much is a new 2025 Lexus RX in Natchez, MS?

A new 2025 Lexus RX starts at $51,015 (including destination charge) in Natchez, MS. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Lexus RX SUV cost in Natchez, MS?

A new 2025 Lexus RX SUV starts at $51,015 in Natchez, MS. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Lexus RX Hybrid which starts at $57,963.
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