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  • Arriving Soon
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Macadamia premium leatherMacadamia premium leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Greensboro (170 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
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    Located in Greensboro, NC / 170 miles away from Myrtle Beach, SC

    Check out this great low mileage vehicle! Both practical and stylish! Turbocharger technology provides forced air induction, enhancing performance whi...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC121238
    Stock: SC37C247
    Listed since: 09-09-2025

  • Arriving Soon
    • Exterior color: IridiumIridium
    • Interior color: Macadamia leatherMacadamia leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Greensboro (170 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
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    Located in Greensboro, NC / 170 miles away from Myrtle Beach, SC

    This Lexus won't be on the lot long! Injecting the driving experience with world class power, precision and modern style! Turbocharger technology prov...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA3SC122129
    Stock: SC38B551
    Listed since: 09-16-2025

  • $51,015
    MSRP $51,015
    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Flow Lexus of Greensboro (170 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Greensboro, NC / 170 miles away from Myrtle Beach, SC

    Looking for a new car at an affordable price? This Lexus won't be on the lot long! Packed with features and truly a pleasure to drive! Turbocharger te...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA5SC066552
    Stock: 6842
    Listed since: 07-09-2025

  • Arriving Soon
    • Exterior color: IridiumIridium
    • Interior color: Macadamia leatherMacadamia leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Greensboro (170 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Greensboro, NC / 170 miles away from Myrtle Beach, SC

    This vehicle won't be on the lot long! You'll appreciate its safety and convenience features! A turbocharger is also included as an economical means o...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC121912
    Stock: SC38C277
    Listed since: 09-13-2025

  • Arriving Soon
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Macadamia premium leatherMacadamia premium leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Greensboro (170 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Greensboro, NC / 170 miles away from Myrtle Beach, SC

    This Lexus won't be on the lot long! A great vehicle and a great value! Turbocharger technology provides forced air induction, enhancing performance w...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA5SC122097
    Stock: SC38C131
    Listed since: 09-16-2025

    • Exterior color: IridiumIridium
    • Interior color: Palomino leatherPalomino leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Greensboro (170 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Greensboro, NC / 170 miles away from Myrtle Beach, SC

    Check out this 2025! It comes equipped with all the standard amenities for your driving enjoyment. The engine breathes better thanks to a turbocharger...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA6SC120052
    Stock: 7003
    Listed since: 08-29-2025

  • $52,044
    MSRP $52,044
    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    This Lexus won't be on the lot long! Injecting the driving experience with world class power, precision and modern style! A turbocharger further enhan...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA1SC066306
    Stock: 38998
    Listed since: 07-04-2025

  • Arriving Soon
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Macadamia premium leatherMacadamia premium leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    Check out this 2025! You'll be impressed by a spectacular blend of technology, style and refinement. All of the premium features expected of a Lexus a...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA0SC102076
    Stock: SC37D052
    Listed since: 09-09-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Palomino leatherPalomino leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    Check out this 2025! A great vehicle and a great value! Turbocharger technology provides forced air induction, enhancing performance while preserving ...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA8SC118920
    Stock: 39209
    Listed since: 08-21-2025

  • New Listing
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Birch leatherBirch leather
    • 5 Seats, 37 City / 34 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    Check out this 2025! Distinctive design and opulent equipment are standard. Lexus prioritized handling and performance with features such as: an autom...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA5SC101280
    Stock: 39286
    Listed since: 09-02-2025

    • Exterior color: Nori Green PearlNori Green Pearl
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    Your satisfaction is our business! This Lexus won't be on the lot long! Both practical and stylish! Top features include power front seats, heated and...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA3SC099643
    Stock: 39403
    Listed since: 09-05-2025

  • $51,015
    MSRP $51,015
    • Exterior color: Nightfall MicaNightfall Mica
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 22 City / 29 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    Don't miss this great Lexus! Distinctive design and opulent equipment are standard. A turbocharger further enhances performance, while also preserving...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBAXSC067597
    Stock: 39204
    Listed since: 08-16-2025

    • Exterior color: IridiumIridium
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    You won't want to miss this excellent value! First and foremost is the striking exterior. All of the premium features expected of a Lexus are offered,...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCA9SC099145
    Stock: 39397
    Listed since: 08-28-2025

  • Arriving Soon
    • Exterior color: Ultra WhiteUltra White
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    This vehicle won't be on the lot long! You'll appreciate its safety and technology features! Turbocharger technology provides forced air induction, en...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA0SC122699
    Stock: SC38B630
    Listed since: 09-19-2025

  • Arriving Soon
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatherBlack leather
    • 5 Seats, 22 City / 29 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    What a great deal on this 2025 Lexus! Breathtaking performance, sumptuous accommodations and jaw dropping good looks! A turbocharger is also included ...

    Features and Specs:

    25 Combined MPG (22 City/29 Highway)

    Listing Information:

    VIN: 2T2BAMBA9SC068773
    Stock: SC38D216
    Listed since: 09-17-2025

  • Arriving Soon
    • Exterior color: IridiumIridium
    • Interior color: Black leatherBlack leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    This Lexus won't be on the lot long! Packed with features and truly a pleasure to drive! The engine breathes better thanks to a turbocharger, improvin...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA0SC122718
    Stock: SC38C105
    Listed since: 09-19-2025

    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatheretteBlack leatherette
    • 5 Seats, 37 City / 34 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    This vehicle won't be on the lot long! Feature-packed and decked out! It includes power seats, a built-in garage door transmitter, automatic dimming d...

    Features and Specs:

    36 Combined MPG (37 City/34 Highway)

    Listing Information:

    VIN: 2T2BBMCAXSC100528
    Stock: 39215
    Listed since: 08-26-2025

  • Arriving Soon
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Palomino leatherPalomino leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    You won't want to miss this excellent value! First and foremost is the striking exterior. A turbocharger is also included as an economical means of in...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC121909
    Stock: SC38C194
    Listed since: 09-12-2025

  • Arriving Soon
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Macadamia premium leatherMacadamia premium leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    This Lexus won't be on the lot long! From front to rear, this model exhibits grace and agility. Turbocharger technology provides forced air induction,...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA7SC121985
    Stock: SC38C314
    Listed since: 09-13-2025

  • Arriving Soon
    • Exterior color: IridiumIridium
    • Interior color: Macadamia leatherMacadamia leather
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    Check out this 2025! It'll satisfy drivers and passengers seeking the ultimate in comfort and refinement. The engine breathes better thanks to a turbo...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA9SC121552
    Stock: SC37D199
    Listed since: 09-10-2025

  • Arriving Soon
    • Exterior color: Ultra WhiteUltra White
    • Interior color: Birch leatheretteBirch leatherette
    • 5 Seats, 21 City / 28 Hwy MPG
    • Flow Lexus of Winston Salem (182 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Winston Salem, NC / 182 miles away from Myrtle Beach, SC

    Check out this 2025! This classically-rendered vehicle is a triumph, continuing to deliver top-notch execution in the luxury segment! A turbocharger i...

    Features and Specs:

    24 Combined MPG (21 City/28 Highway)

    Listing Information:

    VIN: 2T2BAMCA2SC121182
    Stock: SC37C796
    Listed since: 09-09-2025

Showing 127 - 147 out of 3,870 listings
TrimMPGEngineStarting Price
2025 Lexus RX 350 Luxury 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$68,483
2025 Lexus RX 350 Premium Plus 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$61,700
2025 Lexus RX 350 4dr SUV (2.4L 4cyl Turbo 8A)22 - 294-cylinders (gas)$51,015
2025 Lexus RX 350h Luxury 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$69,243
2025 Lexus RX 350h Premium Plus 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$63,648
2025 Lexus RX 350h Premium 4dr SUV AWD (2.5L 4cyl gas/electric hybrid CVT)37 - 344-cylinders (hybrid)$56,655
2025 Lexus RX 350 F SPORT Design 4dr SUV AWD (2.4L 4cyl Turbo 8A)21 - 284-cylinders (gas)$60,615
2025 Lexus RX 350 Premium Plus 4dr SUV (2.4L 4cyl Turbo 8A)22 - 294-cylinders (gas)$61,294

More about the Lexus RX

Edmunds has 3,870 New Lexus RXes for sale near you, including a 2025 RX 350 SUV and a 2025 RX 350 Luxury SUV ranging in price from $51,015 to $69,309.

How much is a new 2025 Lexus RX in Myrtle Beach, SC?

A new 2025 Lexus RX starts at $51,015 (including destination charge) in Myrtle Beach, SC. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Lexus RX SUV cost in Myrtle Beach, SC?

A new 2025 Lexus RX SUV starts at $51,015 in Myrtle Beach, SC. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Lexus RX Hybrid which starts at $56,655.
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