- $47,603MSRP $47,603
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 21 City / 31 Hwy MPG
- Lexus of Jacksonville (313 mi away)(15)
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Located in Jacksonville, FL / 313 miles away from Seneca, SC
This Lexus IS has a strong Intercooled Turbo Premium Unleaded I-4 2.0 L/122 engine powering this Automatic transmission. Window Grid Diversity Antenna...
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D21S5135346
Stock: JS5135346
Listed since: 09-15-2025 - $47,493MSRP $47,493
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 21 City / 31 Hwy MPG
- Lexus of Jacksonville (313 mi away)(15)
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Located in Jacksonville, FL / 313 miles away from Seneca, SC
This Lexus IS has a strong Intercooled Turbo Premium Unleaded I-4 2.0 L/122 engine powering this Automatic transmission. Window Grid Diversity Antenna...
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D22S5135159
Stock: JS5135159
Listed since: 07-04-2025 - $52,343MSRP $52,343
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Jacksonville (313 mi away)(15)
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Located in Jacksonville, FL / 313 miles away from Seneca, SC
This Lexus IS has a strong Premium Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Window Grid Diversity Antenna, Wi-Fi Connect (c...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B29S5090066
Stock: JS5090066
Listed since: 09-11-2025 - $46,733MSRP $46,733
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Jacksonville (313 mi away)(15)
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Located in Jacksonville, FL / 313 miles away from Seneca, SC
This Lexus IS has a dependable Premium Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Wireless Phone Connectivity, Window Grid Di...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B24S5090647
Stock: JS5090647
Listed since: 08-21-2025 - $51,953MSRP $51,953
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Jacksonville (313 mi away)(15)
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Located in Jacksonville, FL / 313 miles away from Seneca, SC
This Lexus IS has a dependable Premium Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Wireless Phone Connectivity, Window Grid Di...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B24S5090508
Stock: JS5090508
Listed since: 09-15-2025 - $51,953MSRP $51,953
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Lexus of Jacksonville (313 mi away)(15)
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Located in Jacksonville, FL / 313 miles away from Seneca, SC
This Lexus IS has a powerful Premium Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Wireless Phone Connectivity, Window Grid Dive...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22S5090569
Stock: JS5090569
Listed since: 08-09-2025 - $52,343MSRP $52,343
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Lexus of Orange Park (317 mi away)(7)
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Located in Jacksonville, FL / 317 miles away from Seneca, SC
This Lexus IS has a powerful Premium Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Wireless Phone Connectivity, Window Grid Dive...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B27S5090308
Stock: LS5090308
Listed since: 09-16-2025 - $51,743MSRP $50,748
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Germain Lexus of Easton (371 mi away)(21)
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Located in Columbus, OH / 371 miles away from Seneca, SC
This New 2025 Lexus IS IS 350 F SPORT Design, is Caviar in color with an Black Nuluxe An interior. Stock Number S127DJ94. You can connect with ...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E28S5041401
Stock: S127DJ94
Listed since: 07-03-2025 - $57,865MSRP
- Exterior color: IridiumIridium
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Germain Lexus of Easton (371 mi away)(21)
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Located in Columbus, OH / 371 miles away from Seneca, SC
This New 2025 Lexus IS IS 350 F SPORT, is Iridium in color with an White Nuluxe An interior. Stock Number S138CZ98. You can connect with us by ...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E25S5042818
Stock: S138CZ98
Listed since: 09-18-2025 - $55,294MSRP $54,858
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Germain Lexus of Easton (371 mi away)(21)
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Located in Columbus, OH / 371 miles away from Seneca, SC
This New 2025 Lexus IS IS 350 F SPORT, is Caviar in color with an Black Nuluxe An interior. Stock Number S130DB48. You can connect with us by c...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E24S5041837
Stock: S130DB48
Listed since: 07-25-2025 - $55,502MSRP $55,068
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Germain Lexus of Easton (371 mi away)(21)
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Located in Columbus, OH / 371 miles away from Seneca, SC
This New 2025 Lexus IS IS 350 F SPORT, is Cloudburst Gray in color with an Black Nuluxe An interior. Stock Number S136CM60. You can connect wit...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27S5042660
Stock: S136CM60
Listed since: 09-09-2025 - $51,059MSRP $51,373
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Germain Lexus of Easton (371 mi away)(21)
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Located in Columbus, OH / 371 miles away from Seneca, SC
This New 2025 Lexus IS IS 350 F SPORT Design, is Cloudburst Gray in color with an Glazed Caramel interior. Stock Number 51016. You can connect ...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E22S5040504
Stock: 51016
Listed since: 05-16-2025 - $51,249MSRP $51,568
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Germain Lexus of Easton (371 mi away)(21)
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Located in Columbus, OH / 371 miles away from Seneca, SC
This New 2025 Lexus IS IS 350 F SPORT Design, is Cloudburst Gray in color with an Rioja Red Nulux interior. Stock Number S134CU73. You can conn...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E29S5042301
Stock: S134CU73
Listed since: 08-23-2025 - $50,352MSRP $50,648
- Exterior color: IncognitoIncognito
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Germain Lexus of Easton (371 mi away)(21)
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Located in Columbus, OH / 371 miles away from Seneca, SC
This New 2025 Lexus IS IS 350 F SPORT Design, is Incognito in color with an Rioja Red Nulux interior. Stock Number S132CT77. You can connect wi...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E28S5042242
Stock: S132CT77
Listed since: 08-21-2025 - $50,748MSRP $50,748
- Exterior color: IncognitoIncognito
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Germain Lexus of Dublin (374 mi away)(8)
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Located in Dublin, OH / 374 miles away from Seneca, SC
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E20S5041425
Stock: 55094
Listed since: 09-15-2025 - $51,943MSRP $51,943
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Germain Lexus of Dublin (374 mi away)(8)
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Located in Dublin, OH / 374 miles away from Seneca, SC
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22S5041271
Stock: 55019
Listed since: 08-12-2025 - $69,508MSRP $69,508
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 17 City / 25 Hwy MPG
- Germain Lexus of Dublin (374 mi away)(8)
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Located in Dublin, OH / 374 miles away from Seneca, SC
Features and Specs:
20 Combined MPG (17 City/25 Highway)
Listing Information:
VIN: JTHAP1D29S5008068
Stock: 55150
Listed since: 09-18-2025 - $68,644MSRP $68,644
- Exterior color: InfraredInfrared
- Interior color: White leatheretteWhite leatherette
- 17 City / 25 Hwy MPG
- Rohrich Lexus (414 mi away)
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Located in Canonsburg, PA / 414 miles away from Seneca, SC
Features and Specs:
20 Combined MPG (17 City/25 Highway)
Listing Information:
VIN: JTHAP1D27S5008182
Stock: L251326
Listed since: 09-13-2025 - $51,873MSRP $51,873
- Exterior color: IridiumIridium
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Rohrich Lexus (414 mi away)
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Located in Canonsburg, PA / 414 miles away from Seneca, SC
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E24S5041675
Stock: L251306
Listed since: 09-09-2025 - $54,663MSRP $54,663
- Exterior color: IridiumIridium
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Rohrich Lexus (414 mi away)
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Located in Canonsburg, PA / 414 miles away from Seneca, SC
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E25S5041636
Stock: L251315
Listed since: 09-11-2025 - $53,368MSRP $53,368
- Exterior color: IridiumIridium
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Rohrich Lexus (414 mi away)
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Located in Canonsburg, PA / 414 miles away from Seneca, SC
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E25S5041443
Stock: L251190
Listed since: 08-14-2025
Consumer Reviews for the Lexus IS
The last of the V8's
Trim | MPG | Engine | Starting Price |
---|---|---|---|
2025 Lexus IS 300 4dr Sedan (2.0L 4cyl Turbo 8A) | 21 - 31 | 4-cylinders (gas) | $47,493 |
2025 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $51,953 |
2025 Lexus IS 350 F SPORT Design 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $46,733 |
2025 Lexus IS 350 F SPORT Design 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $50,648 |
2025 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $51,873 |
2025 Lexus IS 500 F SPORT Performance 4dr Sedan (5.0L 8cyl 8A) | 17 - 25 | 8-cylinders (gas) | $68,644 |
More about the Lexus IS
Edmunds has 669 New Lexus ISes for sale near you, including a 2025 IS 350 F SPORT Design Sedan and a 2025 IS 500 F SPORT Performance Sedan ranging in price from $46,733 to $69,508.
How much is a new 2025 Lexus IS in Seneca, SC?
- A new 2025 Lexus IS starts at $46,733 (including destination charge) in Seneca, SC. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus IS Sedan cost in Seneca, SC?
- A new 2025 Lexus IS Sedan starts at $46,733 in Seneca, SC. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.