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23 listings
- $50,414MSRP
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus El Cajon (4 mi away)
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Located in El Cajon, CA / 4 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B28S5087370
Stock: 4250829
Listed since: 05-15-2025 - $44,413MSRP
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 21 City / 31 Hwy MPG
- Lexus El Cajon (4 mi away)
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Located in El Cajon, CA / 4 miles away from Santee, CA
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHBA1D24S5134795
Stock: 4250835
Listed since: 05-15-2025 - $55,358MSRP
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus El Cajon (4 mi away)
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Located in El Cajon, CA / 4 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B29S5087443
Stock: 4250831
Listed since: 05-15-2025 
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- $52,623MSRP
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Lexus El Cajon (4 mi away)
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Located in El Cajon, CA / 4 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22S5084593
Stock: S103CN18
Listed since: 01-24-2025 - $55,653MSRP
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus El Cajon (4 mi away)
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Located in El Cajon, CA / 4 miles away from Santee, CA
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XS5040742
Stock: S117DI14
Listed since: 04-27-2025 - New Listing$55,208MSRP
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Lexus El Cajon (4 mi away)
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Located in El Cajon, CA / 4 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B27S5087974
Stock: S120EN24
Listed since: 05-13-2025 - $53,578MSRP $56,950
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus San Diego (6 mi away)
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Located in San Diego, CA / 6 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B27S5087537
Stock: 99988
Listed since: 05-07-2025 - $42,235MSRP $44,888
- Exterior color: Ultra WhiteUltra White
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 21 City / 31 Hwy MPG
- Lexus San Diego (6 mi away)
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Located in San Diego, CA / 6 miles away from Santee, CA
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHBA1D21S5134804
Stock: 99986
Listed since: 05-09-2025 - New Listing$53,413MSRP $54,413
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus Escondido (19 mi away)
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Located in Escondido, CA / 19 miles away from Santee, CA
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XS5040529
Stock: E23250
Listed since: 05-08-2025 - Arriving Soon$44,080MSRP $44,080
- Exterior color: Ultra WhiteUltra White
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 21 City / 31 Hwy MPG
- Lexus Carlsbad (27 mi away)
- Home delivery*
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Located in Carlsbad, CA / 27 miles away from Santee, CA
This vehicle won't be on the lot long! Assembled with the most discerning driver in mind. A turbocharger is also included as an economical means of in...
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHBA1D23S5134786
Stock: L34208
Listed since: 05-13-2025 - $53,983MSRP $53,983
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Temecula Valley Lexus (47 mi away)
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Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B20S120EN64
Stock: 20EN64
Listed since: 05-13-2025 - $49,424MSRP $49,424
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Temecula Valley Lexus (47 mi away)
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Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B2XS5086799
Stock: 254258L
Listed since: 04-30-2025 - Arriving Soon$51,543MSRP $51,543
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Temecula Valley Lexus (47 mi away)
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Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B20S5087699
Stock: 254218L
Listed since: 04-23-2025 - $49,395MSRP $49,395
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Temecula Valley Lexus (47 mi away)
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Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B25S5086774
Stock: 253981L
Listed since: 03-20-2025 - $49,749MSRP $49,749
- Exterior color: IridiumIridium
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Temecula Valley Lexus (47 mi away)
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Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22S120EN48
Stock: 20EN48
Listed since: 05-14-2025 - New Listing$49,125MSRP $49,125
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Temecula Valley Lexus (47 mi away)
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Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B29S5088012
Stock: 254294L
Listed since: 05-14-2025 - Arriving Soon$44,425MSRP $44,425
- Exterior color: CaviarCaviar
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 21 City / 31 Hwy MPG
- Temecula Valley Lexus (47 mi away)
Close
Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHBA1D25S5134871
Stock: 254231L
Listed since: 04-26-2025 - Arriving Soon$49,478MSRP $49,478
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Temecula Valley Lexus (47 mi away)
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Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22S5087865
Stock: 087865
Listed since: 05-08-2025 - $49,993MSRP $49,993
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Temecula Valley Lexus (47 mi away)
Close
Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B2XS5087287
Stock: 254135L
Listed since: 04-04-2025 - $49,898MSRP $49,898
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Temecula Valley Lexus (47 mi away)
Close
Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B23S5087437
Stock: 254132L
Listed since: 04-10-2025 - Arriving Soon$53,540MSRP $53,540
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Temecula Valley Lexus (47 mi away)
Close
Located in Temecula, CA / 47 miles away from Santee, CA
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B27S5087635
Stock: 254140L
Listed since: 04-19-2025
Showing 1 - 21 out of 23 listings
Consumer Reviews for the Lexus IS
Read recent reviews for the Lexus IS
The last of the V8's
HJP, 01/10/2024
2024 Lexus IS 500 F SPORT Performance Premium 4dr Sedan (5.0L 8cyl 8A)
Just purchased a 2024 IS500 vector blue as soon as I saw it at the dealer. Happy to pay MSRP as this will be a classic. The car is fast and fun to drive and unlike a hard core M3 or AMG it is actually very comfortable as a daily driver, and that V8 sound is SPECTACULAR! This is probably the best looking sports sedan in the market. Some reviews complain about a dated interior, however I … find it comfortable and very high quality, in fact that is one of the reasons Lexus and Toyotas are so reliable, they are not constantly making drastic changes every year but constantly improving on what is already a top notch fit and finish. If you live in an area with winter snow and ice this might not be a good year round car and the only other possible issue is the rear seat is tight so if you transport big and tall people keep the ride short.
| Trim | MPG | Engine | Starting Price |
|---|---|---|---|
| 2025 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $49,125 |
| 2025 Lexus IS 300 F SPORT Design 4dr Sedan (2.0L 4cyl Turbo 8A) | 21 - 31 | 4-cylinders (gas) | $44,080 |
| 2025 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $54,413 |
More about the Lexus IS
Edmunds has 23 New Lexus ISes for sale near you, including a 2025 IS 300 F SPORT Design Sedan and a 2025 IS 350 F SPORT Sedan ranging in price from $44,080 to $56,950.
How much is a new 2025 Lexus IS in Santee, CA?
- A new 2025 Lexus IS starts at $44,080 (including destination charge) in Santee, CA. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus IS Sedan cost in Santee, CA?
- A new 2025 Lexus IS Sedan starts at $44,080 in Santee, CA. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
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* Delivery of any kind does not apply to Alaska and Hawaii. Contact the dealer for delivery details, restrictions and costs.