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- Arriving Soon$49,263MSRP $49,263
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Tampa Bay (878 mi away)(66)
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Located in Tampa, FL / 878 miles away from Saint Charles, MO
Accessory Package,Lexus Sunshade (Windshield),Rear Bumper Applique,Quick Charge Cables-Mobile,Lane Keeping Assist,Keyless Start,Rear Spoiler,Cooled Fr...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B29S5087720
Stock: S5087720 - Arriving Soon$49,713MSRP $49,713
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Tampa Bay (878 mi away)(66)
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Located in Tampa, FL / 878 miles away from Saint Charles, MO
Illuminated Trunk Sills,Accessory Package,Lexus Sunshade (Windshield),Rear Bumper Applique,Quick Charge Cables-Mobile,Lane Keeping Assist,Keyless Star...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B25S5087908
Stock: S5087908 - $45,288MSRP $45,288
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Black leatheretteBlack leatherette
- 21 City / 31 Hwy MPG
- Lexus of Tampa Bay (878 mi away)(66)
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Located in Tampa, FL / 878 miles away from Saint Charles, MO
Comfort Package,Intuitive Park Assist W/Rear Cross-Traffic Braking,Sun/Moonroof,Premium Paint,Accessory Package,Quick Charge Cables-Mobile,Lane Keepin...
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHCA1D23S5134369
Stock: S5134369
Listed since: 04-16-2025 - Arriving Soon$68,633MSRP $68,633
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 17 City / 25 Hwy MPG
- Lexus of Tampa Bay (878 mi away)(66)
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Located in Tampa, FL / 878 miles away from Saint Charles, MO
Sun/Moonroof,Accessory Package,Lexus Sunshade (Windshield),Rear Bumper Applique,Quick Charge Cables-Mobile,Lane Keeping Assist,Keyless Start,Rear Spoi...
Features and Specs:
20 Combined MPG (17 City/25 Highway)
Listing Information:
VIN: JTHAP1D24S5007667
Stock: S5007667 - Arriving Soon$52,778MSRP $52,778
- Exterior color: InfraredInfrared
- Interior color: White leatheretteWhite leatherette
- 20 City / 28 Hwy MPG
- Lexus of Tampa Bay (878 mi away)(66)
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Located in Tampa, FL / 878 miles away from Saint Charles, MO
Navigation Package,Navigation System,Illuminated Trunk Sills,Accessory Package,Lexus Sunshade (Windshield),Rear Bumper Applique,Quick Charge Cables-Mo...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B23S5087728
Stock: S5087728 - Arriving Soon$49,763MSRP $49,763
- Exterior color: Ultra WhiteUltra White
- Interior color: White leatheretteWhite leatherette
- 20 City / 28 Hwy MPG
- Lexus of Tampa Bay (878 mi away)(66)
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Located in Tampa, FL / 878 miles away from Saint Charles, MO
Accessory Package,Lexus Sunshade (Windshield),Rear Bumper Applique,Quick Charge Cables-Mobile,Lane Keeping Assist,Keyless Start,Rear Spoiler,Cooled Fr...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B26S5087657
Stock: S5087657 - Arriving Soon$49,623MSRP $49,623
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Lexus of Tampa Bay (878 mi away)(66)
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Located in Tampa, FL / 878 miles away from Saint Charles, MO
Illuminated Trunk Sills,Accessory Package,Lexus Sunshade (Windshield),Quick Charge Cables-Mobile,Lane Keeping Assist,Keyless Start,Rear Spoiler,Cooled...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B26S5087500
Stock: S5087500 - $53,813MSRP $53,813
- Exterior color: IridiumIridium
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Ray Catena Lexus of Monmouth (880 mi away)
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Located in Oakhurst, NJ / 880 miles away from Saint Charles, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E20S5040006
Stock: 251003
Listed since: 05-02-2025 - New Listing$51,553MSRP $51,553
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Ray Catena Lexus of Monmouth (880 mi away)
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Located in Oakhurst, NJ / 880 miles away from Saint Charles, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22S5040413
Stock: 251062
Listed since: 05-17-2025 - New Listing$52,143MSRP $52,143
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Ray Catena Lexus of Monmouth (880 mi away)
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Located in Oakhurst, NJ / 880 miles away from Saint Charles, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E20S5040488
Stock: 251096
Listed since: 05-22-2025 - $52,043MSRP $52,043
- Exterior color: CaviarCaviar
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (882 mi away)
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Located in Brooklyn, NY / 882 miles away from Saint Charles, MO
Black 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD, White Nuluxe Artificial Leather.19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E20S5039664
Stock: 250905
Listed since: 03-27-2025 - $56,673MSRP $56,673
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (882 mi away)
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Located in Brooklyn, NY / 882 miles away from Saint Charles, MO
Ultra White 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD, Circuit Red Nul Artificial Leather.19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E25S5038817
Stock: 250702
Listed since: 02-24-2025 - $56,733MSRP $56,733
- Exterior color: IridiumIridium
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (882 mi away)
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Located in Brooklyn, NY / 882 miles away from Saint Charles, MO
Gray 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD, White Nuluxe Artificial Leather.19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29S5039100
Stock: 250796
Listed since: 03-12-2025 - $54,398MSRP $54,398
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (882 mi away)
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Located in Brooklyn, NY / 882 miles away from Saint Charles, MO
Blue 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD, Circuit Red Nul Artificial Leather.19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E26S5039443
Stock: 250919
Listed since: 03-31-2025 - $56,483MSRP $56,483
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (882 mi away)
Close
Located in Brooklyn, NY / 882 miles away from Saint Charles, MO
Black 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD, Circuit Red Nul Artificial Leather.Recent Arrival! 19/26 City/H...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E26S5040317
Stock: 251127
Listed since: 05-09-2025 - $54,443MSRP $54,443
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (882 mi away)
Close
Located in Brooklyn, NY / 882 miles away from Saint Charles, MO
White 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD, Circuit Red Nul Artificial Leather.Recent Arrival! 19/26 City/H...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E24S5040297
Stock: 251162
Listed since: 05-15-2025 - $56,733MSRP $56,733
- Exterior color: Ultra WhiteUltra White
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (882 mi away)
Close
Located in Brooklyn, NY / 882 miles away from Saint Charles, MO
Ultra White 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD, White Nuluxe Artificial Leather.19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E20S5039051
Stock: 250795
Listed since: 03-12-2025 - $54,443MSRP $54,443
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (882 mi away)
Close
Located in Brooklyn, NY / 882 miles away from Saint Charles, MO
White 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD, Black Nuluxe Artificial Leather.19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21S5040001
Stock: 251089
Listed since: 05-01-2025 - $53,973MSRP $53,973
- Exterior color: InfraredInfrared
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (882 mi away)
Close
Located in Brooklyn, NY / 882 miles away from Saint Charles, MO
Red 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD, White Nuluxe Artificial Leather.19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22S5039519
Stock: 250929
Listed since: 04-01-2025 - $49,458MSRP $49,458
- Exterior color: Ultra WhiteUltra White
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brooklyn (882 mi away)
Close
Located in Brooklyn, NY / 882 miles away from Saint Charles, MO
White 2025 Lexus IS 350 F SPORT Design AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V AWD, Glazed Caramel Artificial Leather.19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E24S5039872
Stock: 251000
Listed since: 04-16-2025 - $58,449MSRP $58,449
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Santa Fe (883 mi away)
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Located in Santa Fe, NM / 883 miles away from Saint Charles, MO
Heated/Cooled Seats, Navigation, Moonroof, Satellite Radio, All Wheel Drive, Aluminum Wheels, MOONROOF, NAVIGATION PACKAGE, TRIPLE-BEAM LED HEADLAMPS,...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21S5040547
Stock: S5040547
Listed since: 05-01-2025
Showing 253 - 273 out of 888 listings
Consumer Reviews for the Lexus IS
Read recent reviews for the Lexus IS
The last of the V8's
HJP, 01/10/2024
2024 Lexus IS 500 F SPORT Performance Premium 4dr Sedan (5.0L 8cyl 8A)
Just purchased a 2024 IS500 vector blue as soon as I saw it at the dealer. Happy to pay MSRP as this will be a classic. The car is fast and fun to drive and unlike a hard core M3 or AMG it is actually very comfortable as a daily driver, and that V8 sound is SPECTACULAR! This is probably the best looking sports sedan in the market. Some reviews complain about a dated interior, however I … find it comfortable and very high quality, in fact that is one of the reasons Lexus and Toyotas are so reliable, they are not constantly making drastic changes every year but constantly improving on what is already a top notch fit and finish. If you live in an area with winter snow and ice this might not be a good year round car and the only other possible issue is the rear seat is tight so if you transport big and tall people keep the ride short.
| Trim | MPG | Engine | Starting Price |
|---|---|---|---|
| 2025 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $49,263 |
| 2025 Lexus IS 300 4dr Sedan (2.0L 4cyl Turbo 8A) | 21 - 31 | 4-cylinders (gas) | $45,288 |
| 2025 Lexus IS 500 F SPORT Performance 4dr Sedan (5.0L 8cyl 8A) | 17 - 25 | 8-cylinders (gas) | $68,633 |
| 2025 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $51,553 |
| 2025 Lexus IS 350 F SPORT Design 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $49,458 |
More about the Lexus IS
Edmunds has 888 New Lexus ISes for sale near you, including a 2025 IS 300 Sedan and a 2025 IS 500 F SPORT Performance Sedan ranging in price from $45,288 to $68,633.
How much is a new 2025 Lexus IS in Saint Charles, MO?
- A new 2025 Lexus IS starts at $45,288 (including destination charge) in Saint Charles, MO. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus IS Sedan cost in Saint Charles, MO?
- A new 2025 Lexus IS Sedan starts at $45,288 in Saint Charles, MO. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
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