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682 listings
- Arriving Soon$51,484MSRP $51,484
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Reliable Lexus (499 mi away)
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Located in Springfield, MO / 499 miles away from Picayune, MS
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E29S5042007
Stock: 042007
Listed since: 09-04-2025 - New Listing$46,528MSRP $46,528
- Exterior color: IncognitoIncognito
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 20 City / 28 Hwy MPG
- North Park Lexus At Dominion (538 mi away)(1)
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Located in San Antonio, TX / 538 miles away from Picayune, MS
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B24S5090003
Stock: BD090003
Listed since: 08-29-2025 - Arriving Soon$47,058MSRP $47,058
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 20 City / 28 Hwy MPG
- North Park Lexus At Dominion (538 mi away)(1)
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Located in San Antonio, TX / 538 miles away from Picayune, MS
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B2XS5089924
Stock: S130DL97
Listed since: 07-23-2025 - Arriving Soon$46,684MSRP $46,684
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- North Park Lexus At Dominion (538 mi away)(1)
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Located in San Antonio, TX / 538 miles away from Picayune, MS
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B25S5090334
Stock: S131CW47
Listed since: 08-15-2025 - $47,188MSRP $47,188
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 21 City / 31 Hwy MPG
- Lexus of Fort Myers (550 mi away)
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Located in Fort Myers, FL / 550 miles away from Picayune, MS
Sunroof, Heated Seats, iPod/MP3 Input, Satellite Radio, Back-Up Camera, Turbo, ACCESSORY PACKAGE 2, PREMIUM PACKAGE, INTUITIVE PARK ASSIST W/REAR CROS...
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D27S5134749
Stock: S5134749
Listed since: 05-21-2025 - Arriving Soon$47,598MSRP $47,598
- Exterior color: Ultra WhiteUltra White
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 20 City / 28 Hwy MPG
- Lexus of Fort Myers (550 mi away)
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Located in Fort Myers, FL / 550 miles away from Picayune, MS
Sunroof, Heated Seats, iPod/MP3 Input, Satellite Radio, Back-Up Camera, Alloy Wheels, ACCESSORY PACKAGE 2, MOONROOF, Premium Sound System. Ultra White...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B27S5090304
Stock: S5090304
Listed since: 09-11-2025 - Arriving Soon$47,243MSRP $47,243
- Exterior color: Matador Red MicaMatador Red Mica
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 21 City / 31 Hwy MPG
- Lexus of Fort Myers (550 mi away)
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Located in Fort Myers, FL / 550 miles away from Picayune, MS
Moonroof, Heated Seats, iPod/MP3 Input, Satellite Radio, Back-Up Camera, Turbo Charged Engine, ACCESSORY PACKAGE, PREMIUM PACKAGE, INTUITIVE PARK ASSI...
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D25S5135298
Stock: S5135298
Listed since: 09-11-2025 - $47,598MSRP $47,598
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Fort Myers (550 mi away)
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Located in Fort Myers, FL / 550 miles away from Picayune, MS
Sunroof, Heated Seats, iPod/MP3 Input, Satellite Radio, Back-Up Camera, Alloy Wheels, ACCESSORY PACKAGE 2, MOONROOF, Premium Sound System. Ultra White...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B23S5089828
Stock: S5089828
Listed since: 08-29-2025 - $47,098MSRP $47,098
- Exterior color: CaviarCaviar
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 20 City / 28 Hwy MPG
- Lexus of Fort Myers (550 mi away)
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Located in Fort Myers, FL / 550 miles away from Picayune, MS
Moonroof, Heated Seats, iPod/MP3 Input, Satellite Radio, Back-Up Camera, Aluminum Wheels, ACCESSORY PACKAGE 2, MOONROOF, Premium Sound System. Caviar ...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B28S5089694
Stock: S5089694
Listed since: 09-04-2025 - New Listing$47,508MSRP $47,508
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Fort Myers (550 mi away)
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Located in Fort Myers, FL / 550 miles away from Picayune, MS
Moonroof, Heated Seats, iPod/MP3 Input, Satellite Radio, Back-Up Camera, Aluminum Wheels, ACCESSORY PACKAGE, MOONROOF, Premium Sound System. Ultra Whi...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B25S5090172
Stock: S5090172
Listed since: 09-09-2025 - Arriving Soon$53,668MSRP $53,668
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (555 mi away)(8)
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Located in Manchester, MO / 555 miles away from Picayune, MS
Caviar 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V 19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21S5042010
Stock: 35618
Listed since: 08-02-2025 - $47,598MSRP $47,598
- Exterior color: IridiumIridium
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 20 City / 28 Hwy MPG
- Germain Lexus of Naples (562 mi away)(73)
- Five Star Dealer
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Located in Naples, FL / 562 miles away from Picayune, MS
Iridium 2025 Lexus IS 350 F SPORT Design RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V Glazed Caramel Artificial Leather. Recent Arrival! 20/28 Ci...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B29S5090157
Stock: L251709
Listed since: 09-04-2025 - Arriving Soon$47,333MSRP $47,333
- Exterior color: CaviarCaviar
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 21 City / 31 Hwy MPG
- Germain Lexus of Naples (562 mi away)(73)
- Five Star Dealer
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Located in Naples, FL / 562 miles away from Picayune, MS
Caviar 2025 Lexus IS 300 RWD 8-Speed Automatic 2.0L I4 Turbocharged Glazed Caramel Artificial Leather. 21/31 City/Highway MPG
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D27S5135190
Stock: L251644
Listed since: 08-22-2025 - $47,613MSRP $47,613
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 21 City / 31 Hwy MPG
- Germain Lexus of Naples (562 mi away)(73)
- Five Star Dealer
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Located in Naples, FL / 562 miles away from Picayune, MS
Gray 2025 Lexus IS 300 RWD 8-Speed Automatic 2.0L I4 Turbocharged Rioja Red Nulux Artificial Leather. 21/31 City/Highway MPG
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D29S5134882
Stock: L251358
Listed since: 06-17-2025 - Arriving Soon$47,098MSRP $47,098
- Exterior color: CaviarCaviar
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 20 City / 28 Hwy MPG
- Germain Lexus of Naples (562 mi away)(73)
- Five Star Dealer
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Located in Naples, FL / 562 miles away from Picayune, MS
Caviar 2025 Lexus IS 350 F SPORT Design RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V Rioja Red Nulux Artificial Leather. 20/28 City/Highway MPG
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B20S5089625
Stock: L251645
Listed since: 08-22-2025 - New Listing$50,663MSRP $50,663
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Germain Lexus of Naples (562 mi away)(73)
- Five Star Dealer
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Located in Naples, FL / 562 miles away from Picayune, MS
Gray 2025 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V Black Nuluxe An Artificial Leather. Recent Arrival! 20/28 City/Highwa...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B29S5089810
Stock: L251743
Listed since: 09-11-2025 - New Listing$53,228MSRP $53,228
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Germain Lexus of Naples (562 mi away)(73)
- Five Star Dealer
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Located in Naples, FL / 562 miles away from Picayune, MS
Infra Red 2025 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V Black Nuluxe Artificial Leather. Recent Arrival! 20/28 City/High...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B20S5089999
Stock: L251710
Listed since: 09-08-2025 - $47,113MSRP $47,113
- Exterior color: CaviarCaviar
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 21 City / 31 Hwy MPG
- Germain Lexus of Naples (562 mi away)(73)
- Five Star Dealer
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Located in Naples, FL / 562 miles away from Picayune, MS
Caviar 2025 Lexus IS 300 RWD 8-Speed Automatic 2.0L I4 Turbocharged Rioja Red Nulux Artificial Leather. 21/31 City/Highway MPG
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHDA1D23S5134778
Stock: L251282
Listed since: 05-30-2025 - New Listing$52,611MSRP $50,169
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Jim Hudson Lexus (564 mi away)(16)
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Located in Columbia, SC / 564 miles away from Picayune, MS
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B29S5089824
Stock: C35991
Listed since: 09-07-2025 - Arriving Soon$54,200MSRP $51,758
- Exterior color: IncognitoIncognito
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 20 City / 28 Hwy MPG
- Jim Hudson Lexus (564 mi away)(16)
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Located in Columbia, SC / 564 miles away from Picayune, MS
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B26S5090283
Stock: C35971
Listed since: 07-31-2025 - New Listing$49,611MSRP $47,169
- Exterior color: Ultra WhiteUltra White
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 20 City / 28 Hwy MPG
- Jim Hudson Lexus (564 mi away)(16)
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Located in Columbia, SC / 564 miles away from Picayune, MS
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B26S5091251
Stock: 091251
Listed since: 09-10-2025
Showing 85 - 105 out of 682 listings
Consumer Reviews for the Lexus IS
Read recent reviews for the Lexus IS
The last of the V8's
HJP, 01/10/2024
2024 Lexus IS 500 F SPORT Performance Premium 4dr Sedan (5.0L 8cyl 8A)
Just purchased a 2024 IS500 vector blue as soon as I saw it at the dealer. Happy to pay MSRP as this will be a classic. The car is fast and fun to drive and unlike a hard core M3 or AMG it is actually very comfortable as a daily driver, and that V8 sound is SPECTACULAR! This is probably the best looking sports sedan in the market. Some reviews complain about a dated interior, however I … find it comfortable and very high quality, in fact that is one of the reasons Lexus and Toyotas are so reliable, they are not constantly making drastic changes every year but constantly improving on what is already a top notch fit and finish. If you live in an area with winter snow and ice this might not be a good year round car and the only other possible issue is the rear seat is tight so if you transport big and tall people keep the ride short.
| Trim | MPG | Engine | Starting Price |
|---|---|---|---|
| 2025 Lexus IS 350 F SPORT Design 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $51,484 |
| 2025 Lexus IS 350 F SPORT Design 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $46,528 |
| 2025 Lexus IS 300 4dr Sedan (2.0L 4cyl Turbo 8A) | 21 - 31 | 4-cylinders (gas) | $47,113 |
| 2025 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $53,668 |
| 2025 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $50,169 |
More about the Lexus IS
Edmunds has 682 New Lexus ISes for sale near you, including a 2025 IS 350 F SPORT Design Sedan and a 2025 IS 350 F SPORT Sedan ranging in price from $46,528 to $53,668.
How much is a new 2025 Lexus IS in Picayune, MS?
- A new 2025 Lexus IS starts at $46,528 (including destination charge) in Picayune, MS. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus IS Sedan cost in Picayune, MS?
- A new 2025 Lexus IS Sedan starts at $46,528 in Picayune, MS. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
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