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676 listings
- Arriving Soon$56,070MSRP $56,820
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (864 mi away)(174)
- Five Star Dealer
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Located in Brookfield, WI / 864 miles away from Picayune, MS
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21S5042489
Stock: 042489
Listed since: 09-13-2025 - Arriving Soon$56,570MSRP $57,320
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (864 mi away)(174)
- Five Star Dealer
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Located in Brookfield, WI / 864 miles away from Picayune, MS
FALL SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provides...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27S5042108
Stock: 042108
Listed since: 09-02-2025 - Arriving Soon$49,675MSRP $50,425
- Exterior color: Ultra WhiteUltra White
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Milwaukee (871 mi away)
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Located in Milwaukee, WI / 871 miles away from Picayune, MS
The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provides an exhilarating and smooth ri...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E2XS5042629
Stock: S136CM38
Listed since: 09-07-2025 - $49,675MSRP $50,425
- Exterior color: Ultra WhiteUltra White
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Milwaukee (871 mi away)
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Located in Milwaukee, WI / 871 miles away from Picayune, MS
SUMMER SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E2XS5041996
Stock: L21185
Listed since: 09-12-2025 - $55,825MSRP $56,575
- Exterior color: IncognitoIncognito
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Milwaukee (871 mi away)
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Located in Milwaukee, WI / 871 miles away from Picayune, MS
SUMMER SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E25S5041281
Stock: S126DB07
Listed since: 06-22-2025 - Arriving Soon$55,648MSRP $56,398
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Milwaukee (871 mi away)
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Located in Milwaukee, WI / 871 miles away from Picayune, MS
SUMMER SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28S5041968
Stock: S131CN44
Listed since: 08-15-2025 - $58,668MSRP $58,668
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Classic Lexus (888 mi away)
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Located in Willoughby Hills, OH / 888 miles away from Picayune, MS
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E24S5041790
Stock: 9031947
Listed since: 09-06-2025 - $68,869MSRP
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 17 City / 25 Hwy MPG
- Ourisman Lexus of Rockville (921 mi away)
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Located in Rockville, MD / 921 miles away from Picayune, MS
Features and Specs:
20 Combined MPG (17 City/25 Highway)
Listing Information:
VIN: JTHAP1D20S5007469
Stock: S5007469
Listed since: 03-12-2025 - Arriving Soon$51,863MSRP
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (921 mi away)
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Located in Rockville, MD / 921 miles away from Picayune, MS
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E23S5042042
Stock: S5042042
Listed since: 08-03-2025 - $61,483MSRP
- Exterior color: InfraredInfrared
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (921 mi away)
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Located in Rockville, MD / 921 miles away from Picayune, MS
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XS5039137
Stock: S5039137
Listed since: 08-06-2025 - $55,863MSRP
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (921 mi away)
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Located in Rockville, MD / 921 miles away from Picayune, MS
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E24S5040655
Stock: S5040655
Listed since: 04-19-2025 - $56,223MSRP
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (921 mi away)
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Located in Rockville, MD / 921 miles away from Picayune, MS
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22S5040069
Stock: S5040069
Listed since: 03-12-2025 - $60,865MSRP
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (921 mi away)
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Located in Rockville, MD / 921 miles away from Picayune, MS
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E23S5040520
Stock: S5040520
Listed since: 04-05-2025 - $52,288MSRP $52,288
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Len Stoler Lexus (950 mi away)(55)
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Located in Owings Mills, MD / 950 miles away from Picayune, MS
2025 Lexus IS 350 F SPORT Caviar AWD 3.5L V6 DOHC Dual VVT-i 24V 6-Speed AutomaticAWD, Circuit Red Artificial Leather.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E27S5041850
Stock: L2655 - $49,818MSRP $49,818
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Len Stoler Lexus (950 mi away)(55)
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Located in Owings Mills, MD / 950 miles away from Picayune, MS
2025 Lexus IS 350 F SPORT Design Ultrasonic Blue Mica 2.0 AWD 3.5L V6 DOHC Dual VVT-i 24V 6-Speed AutomaticAWD, Glazed Caramel Artificial Leather.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E26S5042143
Stock: L2742 - $54,283MSRP $54,283
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Len Stoler Lexus (950 mi away)(55)
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Located in Owings Mills, MD / 950 miles away from Picayune, MS
2025 Lexus IS 350 F SPORT Cloudburst Gray AWD 3.5L V6 DOHC Dual VVT-i 24V 6-Speed AutomaticAWD, White W/Black Artificial Leather.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22S5042324
Stock: L2848 - $52,363MSRP $52,363
- Exterior color: IridiumIridium
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Len Stoler Lexus (950 mi away)(55)
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Located in Owings Mills, MD / 950 miles away from Picayune, MS
2025 Lexus IS 350 F SPORT Iridium AWD 3.5L V6 DOHC Dual VVT-i 24V 6-Speed AutomaticAWD, White W/Black Artificial Leather.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E28S5041453
Stock: L2609
Listed since: 08-22-2025 - $53,783MSRP $53,783
- Exterior color: IncognitoIncognito
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Len Stoler Lexus (950 mi away)(55)
Close
Located in Owings Mills, MD / 950 miles away from Picayune, MS
2025 Lexus IS 350 F SPORT Incognito AWD 3.5L V6 DOHC Dual VVT-i 24V 6-Speed AutomaticAWD, Circuit Red Artificial Leather.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E26S5042326
Stock: L2853 - $52,788MSRP $52,788
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Len Stoler Lexus (950 mi away)(55)
Close
Located in Owings Mills, MD / 950 miles away from Picayune, MS
Recent Arrival! 2025 Lexus IS 350 F SPORT Ultra White AWD 3.5L V6 DOHC Dual VVT-i 24V 6-Speed AutomaticAWD, Circuit Red Artificial Leather.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22S5041643
Stock: L2614
Listed since: 09-12-2025 - $49,223MSRP $49,223
- Exterior color: CaviarCaviar
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Len Stoler Lexus (950 mi away)(55)
Close
Located in Owings Mills, MD / 950 miles away from Picayune, MS
2025 Lexus IS 350 F SPORT Design Caviar AWD 3.5L V6 DOHC Dual VVT-i 24V 6-Speed AutomaticAWD, Rioja Red Artificial Leather.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E24S5041864
Stock: L2646 - $54,033MSRP $54,033
- Exterior color: Ultra WhiteUltra White
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Len Stoler Lexus (950 mi away)(55)
Close
Located in Owings Mills, MD / 950 miles away from Picayune, MS
2025 Lexus IS 350 F SPORT Ultra White AWD 3.5L V6 DOHC Dual VVT-i 24V 6-Speed AutomaticAWD, White W/Black Artificial Leather.
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22S5041965
Stock: L2735
Showing 358 - 378 out of 676 listings
Consumer Reviews for the Lexus IS
Read recent reviews for the Lexus IS
The last of the V8's
HJP, 01/10/2024
2024 Lexus IS 500 F SPORT Performance Premium 4dr Sedan (5.0L 8cyl 8A)
Just purchased a 2024 IS500 vector blue as soon as I saw it at the dealer. Happy to pay MSRP as this will be a classic. The car is fast and fun to drive and unlike a hard core M3 or AMG it is actually very comfortable as a daily driver, and that V8 sound is SPECTACULAR! This is probably the best looking sports sedan in the market. Some reviews complain about a dated interior, however I … find it comfortable and very high quality, in fact that is one of the reasons Lexus and Toyotas are so reliable, they are not constantly making drastic changes every year but constantly improving on what is already a top notch fit and finish. If you live in an area with winter snow and ice this might not be a good year round car and the only other possible issue is the rear seat is tight so if you transport big and tall people keep the ride short.
| Trim | MPG | Engine | Starting Price |
|---|---|---|---|
| 2025 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $51,863 |
| 2025 Lexus IS 350 F SPORT Design 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $49,223 |
| 2025 Lexus IS 500 F SPORT Performance 4dr Sedan (5.0L 8cyl 8A) | 17 - 25 | 8-cylinders (gas) | $68,869 |
More about the Lexus IS
Edmunds has 676 New Lexus ISes for sale near you, including a 2025 IS 350 F SPORT Design Sedan and a 2025 IS 500 F SPORT Performance Sedan ranging in price from $49,223 to $68,869.
How much is a new 2025 Lexus IS in Picayune, MS?
- A new 2025 Lexus IS starts at $49,223 (including destination charge) in Picayune, MS. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus IS Sedan cost in Picayune, MS?
- A new 2025 Lexus IS Sedan starts at $49,223 in Picayune, MS. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.Other versions include:
2025 Lexus IS 500 F SPORT which starts at $68,869.
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