Skip to main content
Skip to Filters
814 listings
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Black leatheretteBlack leatherette
    • 20 City / 28 Hwy MPG
    • Flow Lexus of Greensboro (178 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Greensboro, NC / 178 miles away from Murrells Inlet, SC

    This vehicle won't be on the lot long! You'll appreciate its safety and convenience features! Lexus prioritized practicality, efficiency, and style by...

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHBZ1B28S5088237
    Stock: 6786
    Listed since: 06-20-2025

  • Arriving Soon
    • Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
    • Interior color: Black leatheretteBlack leatherette
    • 20 City / 28 Hwy MPG
    • Flow Lexus of Greensboro (178 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Greensboro, NC / 178 miles away from Murrells Inlet, SC

    Check out this 2025! The more time you spend in this vehicle, the more you'll appreciate the engineering that went into it. Lexus infused the interior...

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHBZ1B29S5088392
    Stock: 088392
    Listed since: 06-30-2025

  • $47,313
    MSRP $47,313
    • Exterior color: Eminent White PearlEminent White Pearl
    • Interior color: Black leatheretteBlack leatherette
    • 21 City / 31 Hwy MPG
    • Flow Lexus of Greensboro (178 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Greensboro, NC / 178 miles away from Murrells Inlet, SC

    This vehicle won't be on the lot long! Luxury, power and finesse propel this vehicle ahead of the pack. The engine breathes better thanks to a turboch...

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHDA1D27S5134671
    Stock: 6512
    Listed since: 04-28-2025

  • $45,218
    MSRP $45,218
    • Exterior color: Matador Red MicaMatador Red Mica
    • Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
    • 21 City / 31 Hwy MPG
    • Flow Lexus of Greensboro (178 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Greensboro, NC / 178 miles away from Murrells Inlet, SC

    This Lexus won't be on the lot long! It comes equipped with all the standard amenities for your driving enjoyment. A turbocharger is also included as ...

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHCA1D23S5134453
    Stock: 6406
    Listed since: 04-02-2025

  • Arriving Soon
    • Exterior color: IncognitoIncognito
    • Interior color: Black leatheretteBlack leatherette
    • 20 City / 28 Hwy MPG
    • Flow Lexus of Winston Salem (187 mi away)
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    • Keyless Entry/Start
    Close

    Located in Winston Salem, NC / 187 miles away from Murrells Inlet, SC

    This Lexus won't be on the lot long! You'll appreciate its safety and convenience features! Lexus prioritized handling and performance with features s...

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B26S5088422
    Stock: S122FC05
    Listed since: 06-27-2025

  • $47,188
    MSRP $47,188
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Rioja Red leatheretteRioja Red leatherette
    • 21 City / 31 Hwy MPG
    • Flow Lexus of Winston Salem (187 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Winston Salem, NC / 187 miles away from Murrells Inlet, SC

    This Lexus won't be on the lot long! This is an excellent vehicle at an affordable price! A turbocharger is also included as an economical means of in...

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHDA1D26S5134497
    Stock: 38722
    Listed since: 04-15-2025

    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: White leatheretteWhite leatherette
    • 19 City / 26 Hwy MPG
    • Flow Lexus of Winston Salem (187 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Navigation
    • Sunroof/Moonroof
    Close

    Located in Winston Salem, NC / 187 miles away from Murrells Inlet, SC

    You won't want to miss this excellent value! A great car and a great value! All of the premium features expected of a Lexus are offered, including: he...

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E2XS5040417
    Stock: 39122
    Listed since: 06-26-2025

  • $45,578
    MSRP $45,578
    • Exterior color: IridiumIridium
    • Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
    • 21 City / 31 Hwy MPG
    • Flow Lexus of Winston Salem (187 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Winston Salem, NC / 187 miles away from Murrells Inlet, SC

    This Lexus won't be on the lot long! Both practical and stylish! A turbocharger further enhances performance, while also preserving fuel economy. All ...

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHCA1D29S5134070
    Stock: 38609
    Listed since: 02-17-2025

  • Stock photo**
    $47,098
    MSRP $47,098
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Rioja Red leatheretteRioja Red leatherette
    • 21 City / 31 Hwy MPG
    • Lexus of Orange Park (282 mi away)5 out of 5 stars(7)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Jacksonville, FL / 282 miles away from Murrells Inlet, SC

    This Lexus IS has a dependable Intercooled Turbo Premium Unleaded I-4 2.0 L/122 engine powering this Automatic transmission. Window Grid Diversity Ant...

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHDA1D21S5134911
    Stock: LS5134911
    Listed since: 06-24-2025

  • Stock photo**
    • Exterior color: Cloudburst GrayCloudburst Gray
    • Interior color: Black leatheretteBlack leatherette
    • 20 City / 28 Hwy MPG
    • Lexus of Orange Park (282 mi away)5 out of 5 stars(7)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Jacksonville, FL / 282 miles away from Murrells Inlet, SC

    This Lexus IS has a powerful Premium Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Window Grid Diversity Antenna, Wi-Fi Connect ...

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B2XS5087600
    Stock: LS5087600
    Listed since: 06-10-2025

  • New Listing
    Stock photo**
    • Exterior color: Ultra WhiteUltra White
    • Interior color: Black leatheretteBlack leatherette
    • 20 City / 28 Hwy MPG
    • Lexus of Orange Park (282 mi away)5 out of 5 stars(7)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Jacksonville, FL / 282 miles away from Murrells Inlet, SC

    This Lexus IS has a powerful Premium Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Window Grid Diversity Antenna, Wi-Fi Connect ...

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHBZ1B2XS5088448
    Stock: LS5088448
    Listed since: 05-31-2025

  • New Listing
    • Exterior color: CaviarCaviar
    • Interior color: Black leatheretteBlack leatherette
    • 20 City / 28 Hwy MPG
    • Nalley Lexus Smyrna (315 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Smyrna, GA / 315 miles away from Murrells Inlet, SC

    Caviar 2025 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VRecent Arrival! 20/28 City/Highway MPG

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B27S5088235
    Stock: NLS256555
    Listed since: 07-02-2025

  • New Listing
    Stock photo**
    • Exterior color: Ultra WhiteUltra White
    • Interior color: Black leatheretteBlack leatherette
    • 20 City / 28 Hwy MPG
    • Butler Lexus of South Atlanta (317 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Union City, GA / 317 miles away from Murrells Inlet, SC

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHBZ1B29S5084553
    Stock: S103DH13
    Listed since: 07-03-2025

  • New Listing
    Stock photo**
    • Exterior color: Ultra WhiteUltra White
    • Interior color: Rioja Red leatheretteRioja Red leatherette
    • 19 City / 26 Hwy MPG
    • Butler Lexus of South Atlanta (317 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Union City, GA / 317 miles away from Murrells Inlet, SC

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHBZ1E25S5040870
    Stock: S120EU79
    Listed since: 07-02-2025

    • Exterior color: CaviarCaviar
    • Interior color: Black leatheretteBlack leatherette
    • 20 City / 28 Hwy MPG
    • Lexus of Knoxville (332 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Knoxville, TN / 332 miles away from Murrells Inlet, SC

    Caviar 2025 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V **FULLY SERVICED BY A FACTORY TRAINED TECHNICIAN.Recent Arrival! 20...

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B28S5087823
    Stock: 2370
    Listed since: 06-22-2025

    • Exterior color: CaviarCaviar
    • Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
    • 21 City / 31 Hwy MPG
    • Lexus of Knoxville (332 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Knoxville, TN / 332 miles away from Murrells Inlet, SC

    Caviar 2025 Lexus IS 300 RWD 8-Speed Automatic 2.0L I4 Turbocharged **FULLY SERVICED BY A FACTORY TRAINED TECHNICIAN.21/31 City/Highway MPG

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHDA1D22S5134805
    Stock: 2279
    Listed since: 05-25-2025

    • Exterior color: CaviarCaviar
    • Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
    • 21 City / 31 Hwy MPG
    • Lexus of Knoxville (332 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Knoxville, TN / 332 miles away from Murrells Inlet, SC

    Caviar 2025 Lexus IS 300 RWD 8-Speed Automatic 2.0L I4 Turbocharged **FULLY SERVICED BY A FACTORY TRAINED TECHNICIAN.21/31 City/Highway MPG

    Features and Specs:

    25 Combined MPG (21 City/31 Highway)

    Listing Information:

    VIN: JTHDA1D20S5134544
    Stock: 2128
    Listed since: 04-19-2025

  • Arriving Soon
    Stock photo**
    • Exterior color: CaviarCaviar
    • Interior color: Black leatheretteBlack leatherette
    • 20 City / 28 Hwy MPG
    • Lexus of Knoxville (332 mi away)
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    • Blind Spot Monitorin...
    Close

    Located in Knoxville, TN / 332 miles away from Murrells Inlet, SC

    Caviar 2025 Lexus IS 350 F SPORT RWD 8-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V **FULLY SERVICED BY A FACTORY TRAINED TECHNICIAN.20/28 City/Highway...

    Features and Specs:

    23 Combined MPG (20 City/28 Highway)

    Listing Information:

    VIN: JTHGZ1B29S5088365
    Stock: 2433
    Listed since: 05-28-2025

  • Stock photo**
    • Exterior color: Ultra WhiteUltra White
    • Interior color: Black leatheretteBlack leatherette
    • 17 City / 25 Hwy MPG
    • Ourisman Lexus of Rockville (395 mi away)
    • Back-up camera
    • Bluetooth
    • Sunroof/Moonroof
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Rockville, MD / 395 miles away from Murrells Inlet, SC

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: JTHAP1D20S5007469
    Stock: S5007469
    Listed since: 03-12-2025

    • Exterior color: IridiumIridium
    • Interior color: Circuit Red leatheretteCircuit Red leatherette
    • 19 City / 26 Hwy MPG
    • Ourisman Lexus of Rockville (395 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Rockville, MD / 395 miles away from Murrells Inlet, SC

    Come See Our New 2025 Lexus IS 350 F Sport AWD! Comes Equipped w/Power Tilt and Slide Moonroof, Navigation PKG, F Sport Bolstered Heated and Ventilate...

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E25S5039398
    Stock: S5039398
    Listed since: 03-25-2025

    • Exterior color: CaviarCaviar
    • Interior color: White leatheretteWhite leatherette
    • 19 City / 26 Hwy MPG
    • Ourisman Lexus of Rockville (395 mi away)
    • AWD/4WD
    • Back-up camera
    • Bluetooth
    • Keyless Entry/Start
    • Upgraded Headlights
    Close

    Located in Rockville, MD / 395 miles away from Murrells Inlet, SC

    Features and Specs:

    22 Combined MPG (19 City/26 Highway)

    Listing Information:

    VIN: JTHGZ1E21S5040449
    Stock: S5040449
    Listed since: 05-23-2025

Showing 43 - 63 out of 814 listings

Consumer Reviews for the Lexus IS

Read recent reviews for the Lexus IS
Overall Consumer Rating
4.4 out of 5 stars13 Reviews
Write a vehicle reviewSee all 13 reviews
  • 5 star
    (77%)
  • 4 star
    (8%)
  • 3 star
    (0%)
  • 2 star
    (8%)
  • 1 star
    (8%)
5 out of 5 stars

The last of the V8's

HJP, 01/10/2024
2024 Lexus IS 500 F SPORT Performance Premium 4dr Sedan (5.0L 8cyl 8A)
Just purchased a 2024 IS500 vector blue as soon as I saw it at the dealer. Happy to pay MSRP as this will be a classic. The car is fast and fun to drive and unlike a hard core M3 or AMG it is actually very comfortable as a daily driver, and that V8 sound is SPECTACULAR! This is probably the best looking sports sedan in the market. Some reviews complain about a dated interior, however I … find it comfortable and very high quality, in fact that is one of the reasons Lexus and Toyotas are so reliable, they are not constantly making drastic changes every year but constantly improving on what is already a top notch fit and finish. If you live in an area with winter snow and ice this might not be a good year round car and the only other possible issue is the rear seat is tight so if you transport big and tall people keep the ride short.
Report abuse
TrimMPGEngineStarting Price
2025 Lexus IS 350 F SPORT Design 4dr Sedan (3.5L 6cyl 8A)20 - 286-cylinders (gas)$47,048
2025 Lexus IS 300 4dr Sedan (2.0L 4cyl Turbo 8A)21 - 314-cylinders (gas)$45,218
2025 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A)20 - 286-cylinders (gas)$51,513
2025 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A)19 - 266-cylinders (gas)$53,350
2025 Lexus IS 350 F SPORT Design 4dr Sedan AWD (3.5L 6cyl 6A)19 - 266-cylinders (gas)$50,508
2025 Lexus IS 500 F SPORT Performance 4dr Sedan (5.0L 8cyl 8A)17 - 258-cylinders (gas)$68,869

More about the Lexus IS

Edmunds has 814 New Lexus ISes for sale near you, including a 2025 IS 300 Sedan and a 2025 IS 500 F SPORT Performance Sedan ranging in price from $45,218 to $68,869.

How much is a new 2025 Lexus IS in Murrells Inlet, SC?

A new 2025 Lexus IS starts at $45,218 (including destination charge) in Murrells Inlet, SC. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2025 Lexus IS Sedan cost in Murrells Inlet, SC?

A new 2025 Lexus IS Sedan starts at $45,218 in Murrells Inlet, SC. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2025 Lexus IS 500 F SPORT which starts at $68,869.
Filters
Skip to Results

Applied Filters3Active

Location

Search radiusNationwide
Search radius

Make & Model

Year

New / Used

Price & Payments

Price Rating

Trim

Engine & Drivetrain

Exterior Color

Interior Color

Total Seating

Edmunds Review

Features

Options & Packages

MPG

Listing Details