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850 listings
- New Listing$52,888MSRP $52,888
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Wayzata (233 mi away)
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Located in Wayzata, MN / 233 miles away from Des Moines, IA
03t5 2025 Lexus IS 4D Sedan 350 F SPORT Design AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VAWD, Black Artificial Leather.This IS is well equi...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E29S5040810
Stock: L241548
Listed since: 06-21-2025 - Arriving Soon$59,394MSRP $59,394
- Exterior color: IncognitoIncognito
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Wayzata (233 mi away)
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Located in Wayzata, MN / 233 miles away from Des Moines, IA
Recent Arrival! 01l8 2025 Lexus IS 4D Sedan 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VAWD, Circuit Red Artificial Leather.This ...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E20S5040961
Stock: 040961
Listed since: 06-14-2025 - Arriving Soon$49,562MSRP $50,573
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Maplewood (238 mi away)
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Located in Maplewood, MN / 238 miles away from Des Moines, IA
Recent Arrival! 01l1 2025 Lexus IS 4D Sedan 350 F SPORT Design AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VAWD, Rioja Red Artificial Leather.This...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E2XS5040959
Stock: 040959
Listed since: 06-14-2025 Selling or trading in?
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- $49,191MSRP $50,195
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Maplewood (238 mi away)
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Located in Maplewood, MN / 238 miles away from Des Moines, IA
Recent Arrival! Red 2025 Lexus IS 4D Sedan 350 F SPORT Design AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VAWD, Black Nuluxe An Artificial Leather...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E28S5039907
Stock: DL310933
Listed since: 06-10-2025 - Arriving Soon$49,919MSRP $50,938
- Exterior color: Ultra WhiteUltra White
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Maplewood (238 mi away)
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Located in Maplewood, MN / 238 miles away from Des Moines, IA
0083 2025 Lexus IS 4D Sedan 350 F SPORT Design AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VAWD, Glazed Caramel Artificial Leather.This IS is well...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E20S5040856
Stock: 040856
Listed since: 06-04-2025 - Arriving Soon$55,586MSRP $56,720
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Maplewood (238 mi away)
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Located in Maplewood, MN / 238 miles away from Des Moines, IA
Recent Arrival! 0223 2025 Lexus IS 4D Sedan 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24VAWD, Black Artificial Leather.This IS is well...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29S5041042
Stock: 041042
Listed since: 06-20-2025 - Arriving Soon$50,483MSRP $50,483
- Exterior color: InfraredInfrared
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (265 mi away)(8)
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Located in Manchester, MO / 265 miles away from Des Moines, IA
Infrared 2025 Lexus IS 350 F SPORT Design AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V 19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E24S5040973
Stock: 35423
Listed since: 05-27-2025 - Arriving Soon$56,638MSRP $56,638
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Mungenast Lexus of St Louis (265 mi away)(8)
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Located in Manchester, MO / 265 miles away from Des Moines, IA
Caviar 2025 Lexus IS 350 F SPORT AWD 6-Speed Automatic 3.5L V6 DOHC Dual VVT-i 24V 19/26 City/Highway MPG
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22S5040962
Stock: 35424
Listed since: 05-27-2025 - $51,023MSRP $51,208
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Woodfield Lexus (286 mi away)(38)
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Located in Schaumburg, IL / 286 miles away from Des Moines, IA
F SPORT DESIGN PACKAGE|-INC: STD EQUIP.|ACCESSORY PACKAGE|CARGO NET|REAR BUMPER APPLIQUE|KEY GLOVES|CARPET TRUNK MAT|WHEEL LOCKS|DOOR EDGE FILM BY 3M|...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E2XS5040881
Stock: 251039
Listed since: 06-05-2025 - $56,810MSRP $56,810
- Exterior color: IncognitoIncognito
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (290 mi away)(2)
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Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
2025 Lexus IS 350 F SPORTAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury vehicles. ...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29S5040747
Stock: AL3960
Listed since: 05-29-2025 - Arriving Soon$50,035MSRP $50,035
- Exterior color: IncognitoIncognito
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (290 mi away)(2)
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Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E28S5040958
Stock: AL4026
Listed since: 06-10-2025 - Arriving Soon$50,655MSRP $50,655
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (290 mi away)(2)
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Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E26S5041090
Stock: 3586
Listed since: 06-06-2025 - Arriving Soon$56,785MSRP $56,785
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (290 mi away)(2)
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Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
2025 Lexus IS 350 F SPORTAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury vehicles. ...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21S5040998
Stock: AL4069
Listed since: 06-17-2025 - Arriving Soon$50,655MSRP $50,655
- Exterior color: IridiumIridium
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Arlington (290 mi away)(2)
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Located in Arlington Heights, IL / 290 miles away from Des Moines, IA
2025 Lexus IS 350 F SPORT DesignAt Lexus of Arlington, it’s our mission to provide the drivers of Arlington Heights, IL with prestigious, luxury veh...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E2XS5041075
Stock: 3607
Listed since: 06-05-2025 - Arriving Soon$54,120MSRP $54,870
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (295 mi away)(180)
- Five Star Dealer
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Located in Brookfield, WI / 295 miles away from Des Moines, IA
SUMMER SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E26S5040933
Stock: 040933
Listed since: 06-10-2025 - $56,350MSRP $57,100
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (295 mi away)(180)
- Five Star Dealer
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Located in Brookfield, WI / 295 miles away from Des Moines, IA
SUMMER SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22S5040766
Stock: 28410
Listed since: 06-12-2025 - Arriving Soon$49,100MSRP $49,850
- Exterior color: CaviarCaviar
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Brookfield (295 mi away)(180)
- Five Star Dealer
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Located in Brookfield, WI / 295 miles away from Des Moines, IA
SUMMER SALES EVENT GOING ON NOW!!!The perfect blend of sport and comfort. You deserve to drive something fun and comfortable. The Lexus IS 350 provid...
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E27S5041051
Stock: 041051
Listed since: 06-16-2025 - $50,428MSRP
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Orland (298 mi away)(2)
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Located in Orland Park, IL / 298 miles away from Des Moines, IA
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E23S5040706
Stock: LX0712
Listed since: 06-11-2025 - $50,428MSRP
- Exterior color: CaviarCaviar
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Orland (298 mi away)(2)
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Located in Orland Park, IL / 298 miles away from Des Moines, IA
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E25S5040724
Stock: LX0716
Listed since: 05-16-2025 - $57,310MSRP
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Lexus of Orland (298 mi away)(2)
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Located in Orland Park, IL / 298 miles away from Des Moines, IA
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E2XS5040952
Stock: LX0824
Listed since: 06-13-2025 - $51,113MSRP
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 19 City / 26 Hwy MPG
- Lexus of Orland (298 mi away)(2)
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Located in Orland Park, IL / 298 miles away from Des Moines, IA
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHBZ1E21S5040851
Stock: LX0804
Listed since: 06-17-2025
Showing 1 - 21 out of 850 listings
Consumer Reviews for the Lexus IS
Read recent reviews for the Lexus IS
The last of the V8's
HJP, 01/10/2024
2024 Lexus IS 500 F SPORT Performance Premium 4dr Sedan (5.0L 8cyl 8A)
Just purchased a 2024 IS500 vector blue as soon as I saw it at the dealer. Happy to pay MSRP as this will be a classic. The car is fast and fun to drive and unlike a hard core M3 or AMG it is actually very comfortable as a daily driver, and that V8 sound is SPECTACULAR! This is probably the best looking sports sedan in the market. Some reviews complain about a dated interior, however I … find it comfortable and very high quality, in fact that is one of the reasons Lexus and Toyotas are so reliable, they are not constantly making drastic changes every year but constantly improving on what is already a top notch fit and finish. If you live in an area with winter snow and ice this might not be a good year round car and the only other possible issue is the rear seat is tight so if you transport big and tall people keep the ride short.
| Trim | MPG | Engine | Starting Price |
|---|---|---|---|
| 2025 Lexus IS 350 F SPORT Design 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $49,850 |
| 2025 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $54,870 |
More about the Lexus IS
Edmunds has 850 New Lexus ISes for sale near you, including a 2025 IS 350 F SPORT Design Sedan and a 2025 IS 350 F SPORT Sedan ranging in price from $49,850 to $59,394.
How much is a new 2025 Lexus IS in Des Moines, IA?
- A new 2025 Lexus IS starts at $49,850 (including destination charge) in Des Moines, IA. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus IS Sedan cost in Des Moines, IA?
- A new 2025 Lexus IS Sedan starts at $49,850 in Des Moines, IA. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
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