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786 listings
- $52,123MSRP $52,123
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Orange Park (667 mi away)(7)
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Located in Jacksonville, FL / 667 miles away from Cape Girardeau, MO
This Lexus IS has a powerful Premium Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Window Grid Diversity Antenna, Wi-Fi Connect ...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B2XS5087600
Stock: LS5087600
Listed since: 06-10-2025 - $47,053MSRP $47,053
- Exterior color: Ultrasonic Blue Mica 2.0Ultrasonic Blue Mica 2.0
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Jacksonville (669 mi away)(14)
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Located in Jacksonville, FL / 669 miles away from Cape Girardeau, MO
This Lexus IS has a strong Premium Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Window Grid Diversity Antenna, Wi-Fi Connect (c...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B22S5088766
Stock: JS5088766
Listed since: 07-21-2025 - Arriving Soon$47,133MSRP $47,133
- Exterior color: Ultra WhiteUltra White
- Interior color: Glazed Caramel leatheretteGlazed Caramel leatherette
- 20 City / 28 Hwy MPG
- Lexus of Jacksonville (669 mi away)(14)
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Located in Jacksonville, FL / 669 miles away from Cape Girardeau, MO
This Lexus IS has a powerful Premium Unleaded V-6 3.5 L/211 engine powering this Automatic transmission. Window Grid Diversity Antenna, Wi-Fi Connect ...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B22S5089318
Stock: JS5089318
Listed since: 07-02-2025 - Arriving Soon$68,143MSRP $68,143
- Exterior color: IncognitoIncognito
- Interior color: White leatheretteWhite leatherette
- 17 City / 25 Hwy MPG
- Lexus of Jacksonville (669 mi away)(14)
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Located in Jacksonville, FL / 669 miles away from Cape Girardeau, MO
This Lexus IS has a dependable Premium Unleaded V-8 5.0 L/303 engine powering this Automatic transmission. Window Grid Diversity Antenna, Wi-Fi Connec...
Features and Specs:
20 Combined MPG (17 City/25 Highway)
Listing Information:
VIN: JTHAP1D23S5007899
Stock: JS5007899
Listed since: 06-28-2025 - $56,113MSRP $56,113
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Lakeway (677 mi away)
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Located in Lakeway, TX / 677 miles away from Cape Girardeau, MO
Blk Nuluxe Artificial Leather, 10 Speakers, 4-Wheel Disc Brakes, ABS brakes, Air Conditioning, Alloy wheels, AM/FM radio: SiriusXM, Apple CarPlay/Andr...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B22S5089230
Stock: S126DL59
Listed since: 07-19-2025 - $52,293MSRP $52,293
- Exterior color: CaviarCaviar
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Lakeway (677 mi away)
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Located in Lakeway, TX / 677 miles away from Cape Girardeau, MO
Blk Nuluxe Artificial Leather, 10 Speakers, 4-Wheel Disc Brakes, ABS brakes, Air Conditioning, All-Weather Floor Mats w/All-Weather Trunk Tray, Alloy ...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHGZ1B27S5088977
Stock: S125DK59
Listed since: 07-15-2025 - Arriving Soon$47,184MSRP $47,184
- Exterior color: IncognitoIncognito
- Interior color: Black leatheretteBlack leatherette
- 20 City / 28 Hwy MPG
- Lexus of Lakeway (677 mi away)
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Located in Lakeway, TX / 677 miles away from Cape Girardeau, MO
Blk Perforated Nuluxe Artificial Leather, 10 Speakers, 4-Wheel Disc Brakes, ABS brakes, Air Conditioning, All-Weather Floor Mats w/All-Weather Trunk T...
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B24S5089482
Stock: S127DS00
Listed since: 07-23-2025 - $60,865MSRP
- Exterior color: CaviarCaviar
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (688 mi away)
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Located in Rockville, MD / 688 miles away from Cape Girardeau, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21S5040449
Stock: S5040449
Listed since: 05-23-2025 - $68,869MSRP
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 17 City / 25 Hwy MPG
- Ourisman Lexus of Rockville (688 mi away)
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Located in Rockville, MD / 688 miles away from Cape Girardeau, MO
Features and Specs:
20 Combined MPG (17 City/25 Highway)
Listing Information:
VIN: JTHAP1D20S5007469
Stock: S5007469
Listed since: 03-12-2025 - Arriving Soon$61,235MSRP
- Exterior color: Ultra WhiteUltra White
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (688 mi away)
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Located in Rockville, MD / 688 miles away from Cape Girardeau, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E21S5041309
Stock: S5041309
Listed since: 06-26-2025 - New Listing$53,150MSRP
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (688 mi away)
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Located in Rockville, MD / 688 miles away from Cape Girardeau, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E25S5041085
Stock: S5041085
Listed since: 07-26-2025 - Arriving Soon$53,368MSRP
- Exterior color: CaviarCaviar
- Interior color: White leatheretteWhite leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (688 mi away)
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Located in Rockville, MD / 688 miles away from Cape Girardeau, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E29S5041140
Stock: S5041140
Listed since: 06-11-2025 - $60,865MSRP
- Exterior color: CaviarCaviar
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (688 mi away)
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Located in Rockville, MD / 688 miles away from Cape Girardeau, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E23S5040520
Stock: S5040520
Listed since: 04-05-2025 - $56,223MSRP
- Exterior color: Cloudburst GrayCloudburst Gray
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (688 mi away)
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Located in Rockville, MD / 688 miles away from Cape Girardeau, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E22S5040069
Stock: S5040069
Listed since: 03-12-2025 - $55,863MSRP
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Ourisman Lexus of Rockville (688 mi away)
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Located in Rockville, MD / 688 miles away from Cape Girardeau, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E24S5040655
Stock: S5040655
Listed since: 04-19-2025 - $68,558MSRP
- Exterior color: Ultra WhiteUltra White
- Interior color: Black leatheretteBlack leatherette
- 17 City / 25 Hwy MPG
- Ourisman Lexus of Rockville (688 mi away)
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Located in Rockville, MD / 688 miles away from Cape Girardeau, MO
Features and Specs:
20 Combined MPG (17 City/25 Highway)
Listing Information:
VIN: JTHAP1D21S5007819
Stock: S5007819
Listed since: 07-28-2025 - $51,773MSRP $53,273
- Exterior color: IridiumIridium
- Interior color: Black leatheretteBlack leatherette
- 19 City / 26 Hwy MPG
- Lexus of Towson (719 mi away)(15)
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Located in Towson, MD / 719 miles away from Cape Girardeau, MO
Features and Specs:
22 Combined MPG (19 City/26 Highway)
Listing Information:
VIN: JTHGZ1E23S5040436
Stock: T3019
Listed since: 05-16-2025 - New Listing$68,158MSRP $69,658
- Exterior color: Ultra WhiteUltra White
- Interior color: White leatheretteWhite leatherette
- 17 City / 25 Hwy MPG
- Lexus of Towson (719 mi away)(15)
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Located in Towson, MD / 719 miles away from Cape Girardeau, MO
2025 Lexus IS 500 F SPORT Performance 0083 RWD 5.0L V8 DOHC 32V 8-Speed AutomaticWhite/Black W/Satin Chrome Trim Artificial Leather.
Features and Specs:
20 Combined MPG (17 City/25 Highway)
Listing Information:
VIN: JTHAP1D24S5007930
Stock: T3430
Listed since: 07-26-2025 - $67,228MSRP $68,728
- Exterior color: IncognitoIncognito
- Interior color: Circuit Red leatheretteCircuit Red leatherette
- 17 City / 25 Hwy MPG
- Lexus of Towson (719 mi away)(15)
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Located in Towson, MD / 719 miles away from Cape Girardeau, MO
Features and Specs:
20 Combined MPG (17 City/25 Highway)
Listing Information:
VIN: JTHAP1D28S5007882
Stock: T3292
Listed since: 06-26-2025 - New Listing$45,293MSRP
- Exterior color: Eminent White PearlEminent White Pearl
- Interior color: Black leatheretteBlack leatherette
- 21 City / 31 Hwy MPG
- North Park Lexus At Dominion (741 mi away)(1)
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Located in San Antonio, TX / 741 miles away from Cape Girardeau, MO
Features and Specs:
25 Combined MPG (21 City/31 Highway)
Listing Information:
VIN: JTHCA1D27S5134441
Stock: 9D134441
Listed since: 07-23-2025 - Arriving Soon$47,604MSRP
- Exterior color: Ultra WhiteUltra White
- Interior color: Rioja Red leatheretteRioja Red leatherette
- 20 City / 28 Hwy MPG
- North Park Lexus of San Antonio (742 mi away)(65)
- Five Star Dealer
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Located in San Antonio, TX / 742 miles away from Cape Girardeau, MO
Features and Specs:
23 Combined MPG (20 City/28 Highway)
Listing Information:
VIN: JTHBZ1B25S5088387
Stock: B5088387
Listed since: 07-07-2025
Showing 106 - 126 out of 786 listings
Consumer Reviews for the Lexus IS
Read recent reviews for the Lexus IS
The last of the V8's
HJP, 01/10/2024
2024 Lexus IS 500 F SPORT Performance Premium 4dr Sedan (5.0L 8cyl 8A)
Just purchased a 2024 IS500 vector blue as soon as I saw it at the dealer. Happy to pay MSRP as this will be a classic. The car is fast and fun to drive and unlike a hard core M3 or AMG it is actually very comfortable as a daily driver, and that V8 sound is SPECTACULAR! This is probably the best looking sports sedan in the market. Some reviews complain about a dated interior, however I … find it comfortable and very high quality, in fact that is one of the reasons Lexus and Toyotas are so reliable, they are not constantly making drastic changes every year but constantly improving on what is already a top notch fit and finish. If you live in an area with winter snow and ice this might not be a good year round car and the only other possible issue is the rear seat is tight so if you transport big and tall people keep the ride short.
| Trim | MPG | Engine | Starting Price |
|---|---|---|---|
| 2025 Lexus IS 350 F SPORT 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $52,123 |
| 2025 Lexus IS 350 F SPORT Design 4dr Sedan (3.5L 6cyl 8A) | 20 - 28 | 6-cylinders (gas) | $47,053 |
| 2025 Lexus IS 500 F SPORT Performance 4dr Sedan (5.0L 8cyl 8A) | 17 - 25 | 8-cylinders (gas) | $68,143 |
| 2025 Lexus IS 350 F SPORT 4dr Sedan AWD (3.5L 6cyl 6A) | 19 - 26 | 6-cylinders (gas) | $53,150 |
| 2025 Lexus IS 300 4dr Sedan (2.0L 4cyl Turbo 8A) | 21 - 31 | 4-cylinders (gas) | $45,293 |
More about the Lexus IS
Edmunds has 786 New Lexus ISes for sale near you, including a 2025 IS 300 Sedan and a 2025 IS 500 F SPORT Performance Sedan ranging in price from $45,293 to $69,658.
How much is a new 2025 Lexus IS in Cape Girardeau, MO?
- A new 2025 Lexus IS starts at $45,293 (including destination charge) in Cape Girardeau, MO. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.
How much does a 2025 Lexus IS Sedan cost in Cape Girardeau, MO?
- A new 2025 Lexus IS Sedan starts at $45,293 in Cape Girardeau, MO. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.Other versions include:
2025 Lexus IS 500 F SPORT which starts at $68,558.
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