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    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of St Louis (126 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Saint Louis, MO / 126 miles away from Sikeston, MO

    Moonlight White 2025 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This Vehicle Includes the Following Features:, 4.0L V8, 4MA...

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB0SA338233
    Stock: C26042
    Listed since: 01-23-2026

    • Exterior color: BlackBlack
    • Interior color: Carmine Red/Black premium leatherCarmine Red/Black premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Music City (168 mi away)3 out of 5 stars(2)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Nashville, TN / 168 miles away from Sikeston, MO

    2026 S-Class S 580 Black 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Red Leather.Burmester®: “Burmester is a registered trademark o...

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB8TA367173
    Stock: N367173
    Listed since: 01-11-2026

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Music City (168 mi away)3 out of 5 stars(2)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Nashville, TN / 168 miles away from Sikeston, MO

    2026 S-Class S 580 Black 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Black Leather.Burmester®: “Burmester is a registered trademark...

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB4TA352590
    Stock: N352590
    Listed since: 09-23-2025

    • Exterior color: Nautical Blue MetallicNautical Blue Metallic
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Music City (168 mi away)3 out of 5 stars(2)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Nashville, TN / 168 miles away from Sikeston, MO

    2026 S-Class S 580 Blue 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Brown Leather.Burmester®: “Burmester is a registered trademark ...

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB8TA367075
    Stock: N367075
    Listed since: 01-07-2026

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Music City (168 mi away)3 out of 5 stars(2)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Nashville, TN / 168 miles away from Sikeston, MO

    2026 S-Class S 580 Black 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Beige Leather.Burmester®: “Burmester is a registered trademark...

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GBXTA357762
    Stock: N357762
    Listed since: 10-02-2025

    • Exterior color: Sonoran Brown MetallicSonoran Brown Metallic
    • Interior color: Macchiato Beige/Magma Grey premium leatherMacchiato Beige/Magma Grey premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Music City (168 mi away)3 out of 5 stars(2)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Nashville, TN / 168 miles away from Sikeston, MO

    2026 S-Class S 580 Brown 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Beige Leather.Burmester®: “Burmester is a registered trademark...

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB6TA370413
    Stock: N370413
    Listed since: 02-09-2026

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Music City (168 mi away)3 out of 5 stars(2)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Nashville, TN / 168 miles away from Sikeston, MO

    2026 S-Class S 63 E AMG® Black 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 4.0L V8, 4MATIC®, Black Leather.Burmester®: “Burmester is a registered tra...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB3TA370140
    Stock: N370140
    Listed since: 01-28-2026

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 25 Hwy MPG
    • Mercedes-Benz of Columbia (209 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbia, MO / 209 miles away from Sikeston, MO

    Features and Specs:

    20 Combined MPG (17 City/25 Highway)

    Listing Information:

    VIN: W1K6G7GB3SA331227
    Stock: M5933

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Columbia (209 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbia, MO / 209 miles away from Sikeston, MO

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB2TA371204
    Stock: M6261

    • Exterior color: MANUFAKTUR Moonlight White MetallicMANUFAKTUR Moonlight White Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Columbia (209 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbia, MO / 209 miles away from Sikeston, MO

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB0TA370858
    Stock: M6256

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Columbia (209 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbia, MO / 209 miles away from Sikeston, MO

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB2TA358677
    Stock: M6144

  • New Listing
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Columbia (209 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbia, MO / 209 miles away from Sikeston, MO

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB2TA371381
    Stock: M6270

    • Exterior color: GrayGray
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Columbia (209 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbia, MO / 209 miles away from Sikeston, MO

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB7TA358898
    Stock: M6136

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Columbia (209 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbia, MO / 209 miles away from Sikeston, MO

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB7TA361039
    Stock: M6247

  • New Listing
    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Silver Grey/Black premium leatherSilver Grey/Black premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Columbia (209 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbia, MO / 209 miles away from Sikeston, MO

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB7TA371151
    Stock: M6272

  • New Listing
    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Columbia (209 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbia, MO / 209 miles away from Sikeston, MO

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB9TA370871
    Stock: M6268

    • Interior color: Black premium leatherBlack premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Columbia (209 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Columbia, MO / 209 miles away from Sikeston, MO

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB8TA370798
    Stock: M6257

    • Exterior color: BlackBlack
    • Interior color: MANUFAKTUR Signature Nut Brown/Black premium leatherMANUFAKTUR Signature Nut Brown/Black premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Huntsville (219 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 219 miles away from Sikeston, MO

    Black 2025 Mercedes-Benz S-Class S 63 E AMG® 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®, MANUFAK...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB8SA321367
    Stock: S0199
    Listed since: 12-02-2024

    • Exterior color: Cirrus Silver MetallicCirrus Silver Metallic
    • Interior color: Sienna Brown/Black premium leatherSienna Brown/Black premium leather
    • 17 City / 27 Hwy MPG
    • Mercedes-Benz of Huntsville (219 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 219 miles away from Sikeston, MO

    Cirrus Silver 2026 Mercedes-Benz S-Class S 580 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®, Sienn...

    Features and Specs:

    20 Combined MPG (17 City/27 Highway)

    Listing Information:

    VIN: W1K6G7GB1TA362882
    Stock: T0195
    Listed since: 12-01-2025

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Huntsville (219 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 219 miles away from Sikeston, MO

    Obsidian Black 2026 Mercedes-Benz S-Class S 63 E AMG® 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CBXTA371141
    Stock: T0299
    Listed since: 02-24-2026

    • Exterior color: Obsidian Black MetallicObsidian Black Metallic
    • Interior color: Black premium leatherBlack premium leather
    • 16 mi est. electric range
    • 15 City / 23 Hwy MPG
    • Mercedes-Benz of Huntsville (219 mi away)
    • AWD/4WD
    • Bluetooth
    • Navigation
    • Leather Seats
    • Sunroof/Moonroof
    Close

    Located in Huntsville, AL / 219 miles away from Sikeston, MO

    Obsidian Black 2026 Mercedes-Benz S-Class S 63 E AMG® 4MATIC® 4MATIC® 9-Speed Automatic 4.0L V8 This vehicle is nicely equipped with, 4.0L V8, 4MATIC®...

    Features and Specs:

    18 Combined MPG (15 City/23 Highway)

    Listing Information:

    VIN: W1K6G8CB7TA349873
    Stock: T0055
    Listed since: 09-08-2025

Showing 1 - 21 out of 920 listings

Consumer Reviews for the Mercedes-Benz S-Class

Read recent reviews for the Mercedes-Benz S-Class
Overall Consumer Rating
3.8 out of 5 stars20 Reviews
Write a vehicle reviewSee all 20 reviews
  • 5 star
    (60%)
  • 4 star
    (5%)
  • 3 star
    (10%)
  • 2 star
    (10%)
  • 1 star
    (15%)
3 out of 5 stars

Beautiful looking but beware of quirks.....

sport sedan owner, 05/14/2023
2023 Mercedes-Benz S-Class S 500 4MATIC 4dr Sedan AWD (3.0L 6cyl Twincharger gas/electric mild hybrid 9A)
The car drives great when working. Its looks great and still turn heads, but in 5 months of ownership, it has been in service 3 times. The engine light has gone on with no answer as to what the problem is. The mechanism for the door to open, broke and we were unable to open the door. Lots of quirks to the software and even key to open the doors is suspect. I hope Mercedes learns to be … reliable.
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TrimMPGEngineStarting Price
2025 Mercedes-Benz S-Class S 580 4MATIC 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric mild hybrid 9A)17 - 258-cylinders (mild hybrid)$139,980
2026 Mercedes-Benz S-Class S 580 4MATIC 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric mild hybrid 9A)17 - 278-cylinders (mild hybrid)$61,935
2026 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)15 - 238-cylinders (plug-in hybrid)$191,050
2025 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE 4dr Sedan AWD (4.0L 8cyl Turbo gas/electric plug-in hybrid 9A)15 - 238-cylinders (plug-in hybrid)$210,405

More about the Mercedes-Benz S-Class

Edmunds has 920 New Mercedes-Benz S-Classes for sale near you, including a 2026 S-Class S 580 4MATIC Sedan and a 2026 S-Class AMG S 63 E PERFORMANCE Sedan ranging in price from $61,935 to $213,700.

How much is a new 2026 Mercedes-Benz S-Class in Sikeston, MO?

A new 2026 Mercedes-Benz S-Class starts at $61,935 (including destination charge) in Sikeston, MO. Prices will go up based on the trim level you choose and any options you add. Keep in mind that prices can also vary from one state to another and even from one dealership to the next.

How much does a 2026 Mercedes-Benz S-Class Sedan cost in Sikeston, MO?

A new 2026 Mercedes-Benz S-Class Sedan starts at $61,935 in Sikeston, MO. Prices will vary depending on what trim level you choose. Each state may have different pricing, so make sure you enter your correct ZIP code on Edmunds.
Other versions include:
2026 Mercedes-Benz S-Class AMG S 63 E PERFORMANCE which starts at $191,050.
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